Kirtan Joshi, Tejas Katam, Akshata Hegde, Jianlin Cheng, Randall S Prather, Kristin Whitworth, Kevin Wells, Jeffrey N Bryan, Timothy Hoffman, Bhanu P Telugu, Jussuf T Kaifi, Satyanarayana Rachagani
Pigs are playing an increasingly vital role as translational biomedical models for studying human pathophysiology. The annotation of the pig genome was a huge step forward in translatability of pigs as a biomedical model for various human diseases. Similarities between humans and pigs in terms of anatomy, physiology, genetics, and immunology have allowed pigs to become a comprehensive preclinical model for human diseases. With a diverse range, from craniofacial and ophthalmology to reproduction, wound healing, musculoskeletal, and cancer, pigs have provided a seminal understanding of human pathophysiology...
April 2024: World Journal of Oncology