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Nature and Science of Sleep

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https://www.readbyqxmd.com/read/30349414/inpatient-phase-advance-therapy-for-delayed-sleep-wake-phase-disorder-a-retrospective-study
#1
Masahiro Takeshima, Tetsuo Shimizu, Masaru Echizenya, Hiroyasu Ishikawa, Takashi Kanbayashi
Purpose: The efficacy of inpatient phase-advance therapy among patients with delayed sleep-wake phase disorder (DSWPD) has not been adequately investigated because response rates are considered low. We aimed to examine the efficacy of such treatment in this patient population. Patients and methods: The present retrospective study included data from 66 patients with DSWPD who had been admitted to Akita University Hospital for inpatient phase-advance therapy between September 1, 2005, and April 30, 2018...
2018: Nature and Science of Sleep
https://www.readbyqxmd.com/read/30349413/sleep-related-hypermotor-epilepsy-prevalence-impact-and-management-strategies
#2
REVIEW
Veronica Menghi, Francesca Bisulli, Paolo Tinuper, Lino Nobili
Sleep-related hypermotor epilepsy (SHE), previously called nocturnal frontal lobe epilepsy (NFLE), is a focal epilepsy characterized by asymmetric tonic/dystonic posturing and/or complex hyperkinetic seizures occurring mostly during sleep. SHE fulfills the definition of rare disease with an estimated minimum prevalence of 1.8/100,000 individuals, and it represents about 10% of drug-resistant surgical cases. Although SHE and autosomal-dominant SHE (ADSHE) have been considered benign epileptic conditions for a long time, emerging data have shed light on the severity of this disorder and some peculiar features can impact negatively on the quality of life of SHE patients...
2018: Nature and Science of Sleep
https://www.readbyqxmd.com/read/30323695/comment-on-use-of-blood-biomarkers-to-screen-for-obstructive-sleep-apnea
#3
COMMENT
Burton Abrams
No abstract text is available yet for this article.
2018: Nature and Science of Sleep
https://www.readbyqxmd.com/read/30310337/exploration-of-potential-objective-and-subjective-daily-indicators-of-sleep-health-in-normal-sleepers
#4
Sarah F Allen, Greg J Elder, Laura F Longstaff, Zoe M Gotts, Rachel Sharman, Umair Akram, Jason G Ellis
Purpose: While the concept of "sleep health" has only recently been defined, how it relates to both subjective and objective sleep parameters is yet to be determined. The current study aimed to identify potential indicators of poorer sleep health, from subjective and objective daily sleep characteristics, in normal sleepers. Participants and methods: Eighty-three individuals aged 18-65 years with no history of sleep disorders, chronic physical or psychiatric illnesses, or substance misuse were recruited from the North of England...
2018: Nature and Science of Sleep
https://www.readbyqxmd.com/read/30288132/criteria-for-self-reported-quantitative-sleep-characteristics-of-individuals-who-sought-medical-help-for-disturbed-sleep-a-survey-of-a-representative-sample-of-the-swedish-population
#5
Anna Miley-Åkerstedt, Jerker Hetta, Torbjörn Åkerstedt
Background: The public often seeks rule-of-thumb criteria for good or poor sleep, with a particular emphasis on sleep duration, sleep latency, and the number of awakenings each night. However, very few criteria are available. Aim: The present study sought to identify such criteria. Methods: Whether or not a person has sought medical help for sleep problems was selected as an indicator of poor sleep. The group that was studied constituted a representative sample of the general Swedish population (N=1,128), with a response rate of 72...
2018: Nature and Science of Sleep
https://www.readbyqxmd.com/read/30254502/obstructive-sleep-apnea-in-patients-with-down-syndrome-current-perspectives
#6
REVIEW
Ryne Simpson, Anthony A Oyekan, Zarmina Ehsan, David G Ingram
For individuals with Down syndrome (DS), obstructive sleep apnea (OSA) is a complex disorder with significant clinical consequences. OSA is seen frequently in DS, and when present, it tends to be more severe. This increased prevalence is likely related to common anatomic abnormalities and a greater risk of additional comorbidities such as hypotonia and obesity. Because signs and symptoms do not often correlate with disease, all children and adults with DS should receive routine screening for OSA. Similar to the general population, polysomnography remains the gold standard for diagnosis...
2018: Nature and Science of Sleep
https://www.readbyqxmd.com/read/30233265/obstructive-sleep-apnea-focus-on-myofunctional-therapy
#7
REVIEW
Cláudia Maria de Felício, Franciele Voltarelli da Silva Dias, Luciana Vitaliano Voi Trawitzki
Purpose: Orofacial myofunctional therapy (OMT) is a modality of treatment for children and adults with obstructive sleep apnea (OSA) to promote changes in the musculature of the upper airways. This review summarizes and discusses the effects of OMT on OSA, the therapeutic programs employed, and their possible mechanisms of action. Methods: We conducted an online literature search using the databases MEDLINE/PubMed, EMBASE, and Web of Science. Search terms were "obstructive sleep apnea" in combination with "myofunctional therapy" OR "oropharyngeal exercises" OR "speech therapy"...
2018: Nature and Science of Sleep
https://www.readbyqxmd.com/read/30214331/role-of-normal-sleep-and-sleep-apnea-in-human-memory-processing
#8
REVIEW
Shilpi Ahuja, Rebecca K Chen, Korey Kam, Ward D Pettibone, Ricardo S Osorio, Andrew W Varga
A fundamental problem in the field of obstructive sleep apnea (OSA) and memory is that it has historically minimized the basic neurobiology of sleep's role in memory. Memory formation has been classically divided into phases of encoding, processing/consolidation, and retrieval. An abundance of evidence suggests that sleep plays a critical role specifically in the processing/consolidation phase, but may do so differentially for memories that were encoded using particular brain circuits. In this review, we discuss some of the more established evidence for sleep's function in the processing of declarative, spatial navigational, emotional, and motor/procedural memories and more emerging evidence highlighting sleep's importance in higher order functions such as probabilistic learning, transitive inference, and category/gist learning...
2018: Nature and Science of Sleep
https://www.readbyqxmd.com/read/30197545/from-pillow-to-podium-a-review-on-understanding-sleep-for-elite-athletes
#9
REVIEW
Shannon O'Donnell, Christopher M Beaven, Matthew W Driller
Sleep is considered vital to human health and well-being, and is critical to physiological and cognitive functioning. Elite athletes experience high training and competition demands, and are often exposed to various factors, situations, and environments that can cause sleep impairments. Previous research has shown that athletes commonly experience sleep loss in the lead up to and following competition, which could have significant impacts on their preparation, performance, and recovery. In particular, the results from previous research show significant reductions in total sleep time (~1:40 h:min) and significant increases in sleep latency (~45 minutes) following evening competition...
2018: Nature and Science of Sleep
https://www.readbyqxmd.com/read/30174467/blood-pressure-variability-in-patients-with-obstructive-sleep-apnea-current-perspectives
#10
REVIEW
Oreste Marrone, Maria R Bonsignore
Obstructive sleep apnea (OSA) is often associated with hypertension and other cardiovascular diseases. Blood pressure (BP) variability is part of the assessment of cardiovascular risk. In OSA, BP variability has been studied mainly as very short-term (beat-by-beat) and short-term (24-hour BP profile) variability. BP measured on consecutive heartbeats has been demonstrated to be highly variable, due to repeated peaks during sleep, so that an accurate assessment of nocturnal BP levels in OSA may require peculiar methodologies...
2018: Nature and Science of Sleep
https://www.readbyqxmd.com/read/30123016/sleep-disturbance-after-pediatric-traumatic-brain-injury-critical-knowledge-gaps-remain-for-the-critically-injured
#11
EDITORIAL
Cydni N Williams, Miranda M Lim, Steven A Shea
No abstract text is available yet for this article.
2018: Nature and Science of Sleep
https://www.readbyqxmd.com/read/30123015/the-prevalence-and-awareness-of-sleep-apnea-in-patients-suffering-chronic-pain-an-assessment-using-the-stop-bang-sleep-apnea-questionnaire
#12
Gregory S Tentindo, Scott M Fishman, Chin-Shang Li, Qinlu Wang, Steven D Brass
Purpose: Some patient subsets are at higher risk of sleep apnea, including patients with chronic pain. However, it is unclear whether patients and their caregivers are aware of the possibly increased risk of sleep apnea in this population. Chronic pain is often treated with opioids which may decrease both the central respiratory drive and the patency of the upper airway, potentially contributing to this sleep disorder. Using a self-reporting questionnaire approach in the chronic pain population, this study surveyed patient and caregiver awareness surrounding the risk of sleep apnea...
2018: Nature and Science of Sleep
https://www.readbyqxmd.com/read/30046256/chronic-treatment-with-dexamethasone-alters-clock-gene-expression-and-melatonin-synthesis-in-rat-pineal-gland-at-night
#13
Daniela Meneses-Santos, Daniella do Carmo Buonfiglio, Rodrigo Antonio Peliciari-Garcia, Angela Maria Ramos-Lobo, Divanízia do Nascimento Souza, Angelo Rafael Carpinelli, Carla Roberta de Oliveira Carvalho, Rogério Antônio Laurato Sertie, Sandra Andreotti, Fabio Bessa Lima, Solange Castro Afeche, Emerson Ticona Fioretto, José Cipolla-Neto, Anderson Carlos Marçal
Background: Melatonin is a neuroendocrine hormone that regulates many functions involving energy metabolism and behavior in mammals throughout the light/dark cycle. It is considered an output signal of the central circadian clock, located in the suprachiasmatic nucleus of the hypothalamus. Melatonin synthesis can be influenced by other hormones, such as insulin and glucocorticoids in pathological conditions or during stress. Furthermore, glucocorticoids appear to modulate circadian clock genes in peripheral tissues and are associated with the onset of metabolic diseases...
2018: Nature and Science of Sleep
https://www.readbyqxmd.com/read/30046255/hyperarousal-and-sleep-reactivity-in-insomnia-current-insights
#14
REVIEW
David A Kalmbach, Andrea S Cuamatzi-Castelan, Christine V Tonnu, Kieulinh Michelle Tran, Jason R Anderson, Thomas Roth, Christopher L Drake
Hyperarousal is a key component in all modern etiological models of insomnia disorder. Overall patterns in the literature suggest that over-active neurobiological and psychological systems contribute to difficulty sleeping. Even so, mixed results regarding the specific mechanisms linking hyperarousal to sleep disturbance limit current etiological conceptualizations. Similar basal arousal profiles between individuals with high vs low risk for insomnia in the absence of stress exposure suggest that dysregulated stress "response" rather than general hyperarousal may be a more pertinent marker of risk...
2018: Nature and Science of Sleep
https://www.readbyqxmd.com/read/29950910/larks-owls-swifts-and-woodcocks-among-fruit-flies-differential-responses-of-four-heritable-chronotypes-to-long-and-hot-summer-days
#15
Lyudmila P Zakharenko, Dmitrii V Petrovskii, Arcady A Putilov
Purpose: Drosophila melanogaster and our own species share ( Homo sapiens ) the history of relatively rapid out-of-Africa dispersal. In Eurasia, they had faced a novel adaptive problem of adjustment of their circadian rhythmicity and night sleep episode to seasonal variation in day length and air temperature. Both species usually respond to heat and a short duration of night by reduction of the amount of night sleep and prolongation of "siesta". To further explore similarities between the two species in the ways of adjustment of their sleep-wake behavior to extreme environmental factors, this study examined the possibility to distinguish four extreme chronotypes among fruit flies and the possibility of the differential response of such chronotypes to light and heat stressors...
2018: Nature and Science of Sleep
https://www.readbyqxmd.com/read/29942169/sleeping-tongue-current-perspectives-of-genioglossus-control-in-healthy-individuals-and-patients-with-obstructive-sleep-apnea
#16
REVIEW
Jennifer M Cori, Fergal J O'Donoghue, Amy S Jordan
The focus of this review was on the genioglossus (GG) muscle and its role in maintaining upper airway patency in both healthy individuals and obstructive sleep apnea (OSA) patients. This review provided an overview of GG anatomy and GG control and function during both wakefulness and sleep in healthy individuals and in those with OSA. We reviewed evidence for the role of the GG in OSA pathogenesis and also highlighted abnormalities in GG morphology, responsiveness, tissue movement patterns and neurogenic control that may contribute to or result from OSA...
2018: Nature and Science of Sleep
https://www.readbyqxmd.com/read/29942168/use-of-blood-biomarkers-to-screen-for-obstructive-sleep-apnea
#17
Wesley Elon Fleming, Jon-Erik C Holty, Richard K Bogan, Dennis Hwang, Aliya S Ferouz-Colborn, Rohit Budhiraja, Susan Redline, Edith Mensah-Osman, Nadir Ishag Osman, Qing Li, Armaghan Azad, Susann Podolak, Michael K Samoszuk, Amabelle B Cruz, Yang Bai, Jiuliu Lu, John S Riley, Paula C Southwick
Purpose: Obstructive sleep apnea (OSA) is a highly prevalent disorder associated with increased risk for cardiovascular disease, diabetes, and other chronic conditions. Unfortunately, up to 90% of individuals with OSA remain without a diagnosis or therapy. We assess the relationship between OSA and blood biomarkers, and test the hypothesis that combinations of markers provide a characteristic OSA signature with diagnostic screening value. This validation study was conducted in an independent cohort in order to replicate findings from a prior feasibility study...
2018: Nature and Science of Sleep
https://www.readbyqxmd.com/read/29881316/relevance-of-deprivation-studies-in-understanding-rapid-eye-movement-sleep
#18
REVIEW
Rachna Mehta, Shafa Khan, Birendra N Mallick
Rapid eye movement sleep (REMS) is a unique phenomenon essential for maintaining normal physiological processes and is expressed at least in species higher in the evolution. The basic scaffold of the neuronal network responsible for REMS regulation is present in the brainstem, which may be directly or indirectly influenced by most other physiological processes. It is regulated by the neurons in the brainstem. Various manipulations including chemical, elec-trophysiological, lesion, stimulation, behavioral, ontogenic and deprivation studies have been designed to understand REMS genesis, maintenance, physiology and functional significance...
2018: Nature and Science of Sleep
https://www.readbyqxmd.com/read/29750062/mask-humidity-during-cpap-influence-of-ambient-temperature-heated-humidification-and-heated-tubing
#19
Georg Nilius, Ulrike Domanski, Maik Schroeder, Holger Woehrle, Andrea Graml, Karl-Josef Franke
Purpose: Mucosal drying during continuous positive airway pressure (CPAP) therapy is problematic for many patients. This study assessed the influence of ambient relative humidity (rH) and air temperature (T) in winter and summer on mask humidity during CPAP, with and without mask leak, and with or without heated humidification ± heated tubing. Methods: CPAP (8 and 12 cmH2 O) without humidification (no humidity [nH]), with heated humidification controlled by ambient temperature and humidity (heated humidity [HH]) and HH plus heated tubing climate line (CL), with and without leakage, were compared in 18 subjects with OSA during summer and winter...
2018: Nature and Science of Sleep
https://www.readbyqxmd.com/read/29731671/the-level-of-observed-physical-movement-accompanying-periodic-limb-movements-measured-in-a-clinical-sleep-population
#20
Robert G Hooper
Study objectives: Periodic limb movements (PLMs) are routinely measured during polysomnogram (PSG) testing. During the early years of sleep testing, physical movements were identified and over time, consensus ultimately led to the current definitions of movement disorders including criteria used to measure PLMs on PSG testing. There has been considerable debate about the clinical importance of the PLMs measured during PSG testing. Over the last decade, the author has observed significant variations in the actual visible physical movements observed with a PLM event...
2018: Nature and Science of Sleep
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