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Clinical Medicine Insights. Gastroenterology

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https://www.readbyqxmd.com/read/30305797/impact-of-video-aid-on-quality-of-bowel-preparation-among-patients-undergoing-outpatient-screening-colonoscopy
#1
Sanna Fatima, Deepanshu Jain, Christopher Hibbard
Aim: To investigate the effect of video aid on quality of bowel preparation. Study: A retrospective study was done on patients undergoing outpatient screening colonoscopy. All subjects received educational video prior to colonoscopy in addition to the standard counseling. Patient charts were reviewed to collect data regarding quality of bowel preparation (adequate or inadequate). The study population was stratified into four groups according to viewing status: Group I 0% (control group), Group II <50%, Group III >50% to <75%, and Group IV watched ⩾75% of the video...
2018: Clinical Medicine Insights. Gastroenterology
https://www.readbyqxmd.com/read/30262989/pancreatic-extramedullary-plasmacytoma-presenting-as-a-pancreatic-mass
#2
Michelle Le, Balarama Krishna Surapaneni, Vardhmaan Jain, Rakesh Vinayek, Sudhir K Dutta
Extramedullary plasmacytomas (EMP) are a subcategory of plasma cell neoplasm that involves organs outside the bone marrow. Involvement of the pancreas is relatively rare, reported in only 2.3% of autopsies. Radiologic findings in plasmacytoma are nonspecific, but endoscopic ultrasound fine-needle aspiration is a fast and reliable technique to acquire a histologic sample for initial diagnosis. Recently, the use of fluorine-18 fluorodeoxyglucose PET/CT has been recommended in patients with active multiple myeloma and solitary plasmacytoma...
2018: Clinical Medicine Insights. Gastroenterology
https://www.readbyqxmd.com/read/30083065/plasma-free-amino-acid-profiles-in-crohn-s-disease-relationship-with-the-crohn-disease-activity-index
#3
Toshimi Chiba, Kazuyuki Suzuki, Takayuki Matsumoto
We aimed to clarify the relationship between plasma-free amino acid (PFAA) profiles and the Crohn's disease (CD) activity index (CDAI) in patients with CD. Methods: We measured fasting PFAA concentrations in 29 patients with CD and their correlation with disease activity. Results: In all patients, significant correlations were noted between CDAI and concentrations of valine, methionine, leucine, histidine, tryptophan, alanine, tyrosine, total amino acids (TAAs), nonessential amino acids (NEAAs), essential amino acids (EAAs), and branched-chain amino acids (BCAAs)...
2018: Clinical Medicine Insights. Gastroenterology
https://www.readbyqxmd.com/read/30083064/esophageal-adenocarcinoma-opportunities-for-targeted-prevention-in-ohio
#4
Julie A Stephens, James L Fisher, Jessica L Krok-Schoen, Ryan D Baltic, Holly L Sobotka, Electra D Paskett
Objective: The incidence of esophageal adenocarcinoma, one of the most lethal gastroenterological diseases, has been increasing since the 1960s. Prevention of esophageal adenocarcinoma is important because no early detection screening programs have been shown to reduce mortality. Obesity, gastroesophageal reflux disease, and tobacco smoking are risk factors for esophageal adenocarcinoma. Due to the high prevalence in Ohio of obesity (32.6%) and cigarette smoking (21.0%), this study sought to identify trends and patterns of these risk factors and esophageal adenocarcinoma in Ohio as compared with the United States...
2018: Clinical Medicine Insights. Gastroenterology
https://www.readbyqxmd.com/read/30083063/gastroduodenal-tuberculosis-a-case-series-and-review-of-literature
#5
Suhas Udgirkar, Ravindra Surude, Vinay Zanwar, Sanjay Chandnani, Qais Contractor, Pravin Rathi
Gastroduodenal tuberculosis is infrequently seen in day-to-day clinical practice with few cases reported in the literature. It is usually associated with features of gastric outlet obstruction. This is a case series of 4 patients with 2 of them having associated lower gastrointestinal involvement. One of them resembled a growth in the cardia of the stomach which responded to antitubercular drugs. Another had duodenal erosions with portal lymph node enlargement which responded to antitubercular drug treatment...
2018: Clinical Medicine Insights. Gastroenterology
https://www.readbyqxmd.com/read/30057447/a-case-of-acute-severe-hepatotoxicity-and-mild-constriction-of-common-bile-duct-associated-with-ingestion-of-green-tea-extract-a-clinical-challenge
#6
Balarama Krishna Surapaneni, Michelle Le, Julian Jakobovits, Rakesh Vinayek, Sudhir Dutta
Consumption of herbal and dietary supplements (HDS) has increased worldwide as potential treatment for weight reduction and metabolic enhancement. However, it has been reported that HDS can cause liver injury which accounts for 20% of hepatotoxicity in the United States. Prevention of HDS induced liver injury remains a challenge due to difficulties in identifying the hepatotoxins in these preparations and lack of federal regulations for dietary supplements. We report a case of acute severe hepatic necrosis presumably due to consumption of nutritional supplement advertised to boost vitality and stem cells in human body...
2018: Clinical Medicine Insights. Gastroenterology
https://www.readbyqxmd.com/read/30013416/an-evidence-based-review-of-statin-use-in-patients-with-nonalcoholic-fatty-liver-disease
#7
REVIEW
Meredith A Sigler, Lee Congdon, Krystal L Edwards
Background: Nonalcoholic fatty liver disease (NAFLD) is a common complication in patients with metabolic syndrome. The role of statin therapy specifically for the treatment of NAFLD remains unknown. The aim of this review is to discuss outcomes of recent articles analyzing statin therapy in patients with NAFLD. Findings: A total of 12 trials met the inclusion criteria. Statins were not found to increase the prevalence of NAFLD once confounding variables were considered...
2018: Clinical Medicine Insights. Gastroenterology
https://www.readbyqxmd.com/read/30013415/successful-endoscopic-treatment-of-post-esophagectomy-refractory-reflux-using-overstitch-the-first-clinical-case
#8
Hirotsugu Nagase, Makoto Yamasaki, Yoshitomo Yanagimoto, Takashi Kanemura, Shigeyoshi Higashi, Kota Momose, Ryo Kato, Yasuhiro Miyazaki, Tomoki Makino, Tsuyoshi Takahashi, Yukinori Kurokawa, Hiroshi Miyata, Shuji Takiguchi, Masaki Mori, Yuichiro Doki, Kiyokazu Nakajima
Aims: The reflux of duodeno-gastric contents into the remnant esophagus (gastric tube-esophageal reflux: GTER) is a significant issues in long-term esophageal cancer survivors after radical esophagectomy. We attempted endoscopic valve (funnel) creation for prevention for GTER using OverStitch endoscopic suturing system. Methods: The OverStitch was mounted onto a standard double-channel endoscope. Under general anesthesia, the funnel creation was attempted by placing semi-full thickness sutures on the gastric wall, at 3 cm distal to the primary esophago-gastric anastomosis...
2018: Clinical Medicine Insights. Gastroenterology
https://www.readbyqxmd.com/read/29795991/gastrointestinal-lesions-in-african-american-patients-with-iron-deficiency-anemia
#9
Hassan Brim, Anahita Shahnazi, Mehdi Nouraie, Dilhana Badurdeen, Adeyinka O Laiyemo, Tahmineh Haidary, Ali Afsari, Hassan Ashktorab
Background: Iron deficiency anemia (IDA) is a frequent disorder that is associated with many serious diseases. However, the findings of an evaluation of IDA-associated gastrointestinal disorders are lacking among African American patients. Aim: To determine the most prevalent gastrointestinal lesions among African American patients with IDA especially in young men. Methods: We reviewed medical records (n = 422) of patients referred for evaluation of IDA from 2008 to 2012...
2018: Clinical Medicine Insights. Gastroenterology
https://www.readbyqxmd.com/read/29686488/the-morbidity-and-mortality-of-laparoscopic-appendectomy-in-patients-with-cirrhosis
#10
Yasir Al-Azzawi, Yasir Al-Abboodi, Matthew Fasullo, Tarek Najuib
Introduction: The perioperative mortality is significantly higher in patients with cirrhosis undergoing certain surgical procedures. In this study, we examined the inpatient perioperative mortality and morbidities in cirrhotic people who underwent laparoscopic appendectomy. Methods: We performed a retrospective analysis using the National Inpatient Sample database for 2010. Inclusion criteria were all race and sex who are 18 years or older. Those who have laparoscopic appendectomy and have a history of liver cirrhosis were assigned to case group...
2018: Clinical Medicine Insights. Gastroenterology
https://www.readbyqxmd.com/read/29497344/orbital-inflammatory-complications-of-crohn-s-disease-a-rare-case-series
#11
Tanya M Monaghan, Giorgio Albanese, Philip Kaye, James D Thomas, Lorraine C Abercrombie, Gordon W Moran
Orbital inflammatory disease is a rare ophthalmic manifestation of Crohn's disease. Inflammation is characteristically nonspecific, involving one or multiple structures of the orbit. Mechanisms of disease and optimal methods of treatment are poorly understood. The aim of this report is to present 3 cases of orbital involvement in Crohn's disease. A retrospective case note review of patients with orbital inflammatory disease and Crohn's disease was performed at our academic center to determine the clinical, imaging, and histopathologic features of this condition and its relationship to intestinal Crohn's disease...
2018: Clinical Medicine Insights. Gastroenterology
https://www.readbyqxmd.com/read/29449779/-saccharomyces-boulardii-cncm-i-745-improves-intestinal-enzyme-function-a-trophic-effects-review
#12
REVIEW
Margret I Moré, Yvan Vandenplas
Several properties of the probiotic medicinal yeast Saccharomyces boulardii CNCM I-745 contribute to its efficacy to prevent or treat diarrhoea. Besides immunologic effects, pathogen-binding and anti-toxin effects, as well as positive effects on the microbiota, S boulardii CNCM I-745 also has pronounced effects on digestive enzymes of the brush border membrane, known as trophic effects. The latter are the focus of this review. Literature has been reviewed after searching Medline and PMC databases. All relevant non-clinical and clinical studies are summarized...
2018: Clinical Medicine Insights. Gastroenterology
https://www.readbyqxmd.com/read/29398926/a-randomized-controlled-trial-comparing-the-depth-of-maximal-insertion-between-anterograde-single-balloon-versus-spiral-enteroscopy
#13
Robert A Moran, Sindhu Barola, Joanna K Law, Stuart K Amateau, Daniil Rolshud, Erin Corless, Vandhana Kiswani, Vikesh K Singh, Anthony N Kalloo, Mouen A Khashab, Anne Marie Lennon, Patrick I Okolo, Vivek Kumbhari
Background: Three device-assisted deep endoscopic platforms presently exist and are available for clinical use: double-balloon enteroscopy, single-balloon enteroscopy (SBE), and spiral enteroscopy (SE). In a retrospective study, SE was associated with a greater depth of maximal insertion (DMI) with similar diagnostic yields and procedure time as compared with SBE. Aims: This was a prospective, randomized comparison of SE and SBE with respect to DMI, diagnostic yield, procedure time, and rate of adverse events...
2018: Clinical Medicine Insights. Gastroenterology
https://www.readbyqxmd.com/read/29662332/corrigendum
#14
(no author information available yet)
[This corrects the article DOI: 10.1177/1179552217711430.].
2017: Clinical Medicine Insights. Gastroenterology
https://www.readbyqxmd.com/read/29308020/a-case-of-gastric-ulcer-with-mucosal-bridge
#15
Tomoyuki Kitagawa, Ryo Masaoka, Yasumi Katayama, Masaya Tamano
Endoscopic images of the mucosal bridge with gastric ulcer are unusual. The mucosal bridge is presumed to have changed to a special form based on repeated development of gastric ulcer. The clinical course of mucosal bridge is unclear.
2017: Clinical Medicine Insights. Gastroenterology
https://www.readbyqxmd.com/read/29276421/adaptive-returns-of-deficient-systemic-plasma-immunoglobulin-g-levels-as-rehabilitation-biomarker-after-emergency-colectomy-for-fulminant-ulcerative-colitis
#16
Alexander T Hawkins, Jun W Um, Amosy E M'Koma
Restorative proctocolectomy (RPC) with ileal pouch-anal anastomosis (IPAA) is the standard surgical treatment for ulcerative colitis (UC). Emergency colectomies are performed for fulminant colitis (ie, toxic megacolon, profuse bleeding, perforation, or sepsis). The RPC and IPAA involve manipulation of the proximal ileum, which may influence the essential physiological function of gut-associated lymphoid tissues. Circulating plasma immunoglobulin G (p-IgG) deficiency is observed in patients with fulminant UC...
2017: Clinical Medicine Insights. Gastroenterology
https://www.readbyqxmd.com/read/28912636/should-emergency-endoscopy-be-performed-in-all-patients-with-suspected-colonic-diverticular-hemorrhage
#17
Takeshi Uehara, Satohiro Matsumoto, Hiroyuki Miyatani, Hirosato Mashima
OBJECTIVE: We attempted to develop a scoring system for facilitating decision making regarding the performance of emergency endoscopy in patients with colonic diverticular hemorrhage. METHODS: This study involved analysis of the data of 178 patients who presented with hematochezia and were diagnosed as having colonic diverticular hemorrhage by colonoscopy. The patients were divided into 2 groups depending on whether the bleeding source was identified or not at the initial endoscopy (source-identified and source-not-identified groups), and on the basis of the results obtained, we established a scoring system for predicting successful identification of the bleeding source...
2017: Clinical Medicine Insights. Gastroenterology
https://www.readbyqxmd.com/read/28894394/normative-values-for-colonic-transit-time-and-patient-assessment-of-constipation-in-adults-with-functional-constipation-systematic-review-with-meta-analysis
#18
REVIEW
Larry E Miller, Alvin Ibarra, Arthur C Ouwehand
Availability of normative patient outcome data may assist in designing experiments and estimating sample sizes. The purpose of this review was to determine normative ranges for colonic transit time (CTT), Patient Assessment of Constipation-Symptoms (PAC-SYM), and Patient Assessment of Constipation-Quality of Life (PAC-QOL) in adults diagnosed with functional constipation per Rome III guidelines. Pooled estimates were derived from random-effects meta-analysis. Meta-regression was used to explore sources of heterogeneity among studies...
2017: Clinical Medicine Insights. Gastroenterology
https://www.readbyqxmd.com/read/28894393/review-of-rifaximin-latest-treatment-frontier-for-irritable-bowel-syndrome-mechanism-of-action-and-clinical-profile
#19
Kamesh Gupta, Harparam Singh Ghuman, Shivani Vijay Handa
BACKGROUND: Irritable bowel syndrome is classified as a functional gastrointestinal disorder with the primary symptom of abdominal pain in conjunction with bloating and bowel movement disorder. It affects up to 15% of the world's population. Among its subtypes, the most common is diarrhoea predominant. However, the current treatment options for diarrhoea-predominant irritable bowel syndrome have had not very promising results; most, such as antispasmodics, only provide partial symptomatic relief...
2017: Clinical Medicine Insights. Gastroenterology
https://www.readbyqxmd.com/read/28634431/the-aftermath-of-a-hepatic-artery-aneurysm-a-rare-etiology-of-biliary-obstruction
#20
Catherine Linzay, Abhishek Seth, Kunal Suryawala, Ankur Sheth, Moheb Boktor, John Bienvenu, Robby Rahim, Guillermo P Sangster, Paul A Jordan
BACKGROUND: Hepatic artery aneurysms (HAAs) constitute 14% to 20% of visceral artery aneurysms. Most HAAs are asymptomatic. Although rare, obstructive jaundice due to external bile duct compression or rupture of the HAA into the biliary tree with occlusion of the lumen from blood clots has been reported. CASE PRESENTATION: A 56-year-old white man presented to an outside hospital with symptoms of obstructive jaundice, including abdominal pain and yellowing of the skin...
2017: Clinical Medicine Insights. Gastroenterology
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