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Journal of Neonatal-perinatal Medicine

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https://www.readbyqxmd.com/read/27834786/use-of-naloxone-to-minimize-extubation-failure-after-premedication-for-insure-procedure-in-preterm-neonates
#1
A Elmekkawi, D Abdelgadir, J Van Dyk, J Choudhury, M Dunn
OBJECTIVES: A new guideline for the early respiratory management of preterm infants was recently introduced in our NICU. This case series describes the clinical courses of a group of preterm infants managed according to this guideline, and reports the rates of successful extubation within 30 minutes of surfactant administration with and without the use of naloxone and adverse events encountered. STUDY DESIGN: Descriptive case series of all preterm babies admitted to our unit who were candidates for INSURE procedure with premedication from August 2012 to August 2013...
November 9, 2016: Journal of Neonatal-perinatal Medicine
https://www.readbyqxmd.com/read/27834785/physiological-effects-of-a%C3%A2-single-chest-physiotherapy-session-in-mechanically-ventilated-and-extubated-preterm-neonates
#2
Y Mehta, J Shetye, R Nanavati, A Mehta
OBJECTIVE: To assess the changes on various physiological cardio-respiratory parameters with a single chest physiotherapy session in mechanically ventilated and extubated preterm neonates with respiratory distress syndrome. STUDY DESIGN: This is a prospective observational study in neonatal intensive care unit setting. Sixty preterm neonates with respiratory distress syndrome, thirty mechanically ventilated and thirty extubated preterm neonates requiring chest physiotherapy were enrolled in the study...
November 9, 2016: Journal of Neonatal-perinatal Medicine
https://www.readbyqxmd.com/read/27834784/lost-in-explanation-lessons-learned-from-audio-recordings-and-surveys-of-the-antenatal-consultation
#3
E M Studer, K L Marc-Aurele
OBJECTIVE: Determine content of antenatal prematurity consultations and identify factors associated with satisfaction. DESIGN: This is an observational study of consultations for possible preterm delivery. Consultations were audio-recorded and analyzed. Parents and physicians were surveyed post-consultation. RESULTS: We analyzed 17 audio-recordings. Mean gestation was 28 weeks. Frequency of topics discussed were: antenatal steroids 82%, intubation 82%, breast milk 76%, time in NICU 65%, development 59%, and survival 53%...
November 9, 2016: Journal of Neonatal-perinatal Medicine
https://www.readbyqxmd.com/read/27834783/neonatal-beh%C3%A3-et-s-disease-with-raynaud-phenomenon
#4
J R Fernández-Fructuoso, S Gil-Sánchez, E Gómez-Santos, J M Lloreda-García, S Sevilla-Denia, J L Leante-Castellanos
We report a new clinical manifestation of neonatal Behcet's disease. A newborn from a mother with active Behcet's disease during pregnancy, who develops vasomotor phenomena (Raynaud) with oral ulcerations in the second day of life. Neonatal mucocutaneous lesions have been reported previously in few newborns of pregnant women with active Behçet disease. Although neonatal disease is a very infrequent situation, with a mostly transient and favorable course, clinicians should be aware of serious potential complications associated with this entity...
November 9, 2016: Journal of Neonatal-perinatal Medicine
https://www.readbyqxmd.com/read/27834782/alarms-oxygen-saturations-and-spo2-averaging-time-in-the-nicu
#5
C McClure, S Young Jang, K Fairchild
BACKGROUND: Alarm overload is a significant concern in the Neonatal Intensive Care Unit (NICU). Selecting a longer oxygen saturation (SpO2) averaging time will reduce the number of alarms but may mask fluctuations in oxygenation. OBJECTIVE: Characterize bedside monitor alarms in the NICU and estimate the impact of longer SpO2 averaging time and alarm delay. METHODS: All bedside monitor alarms were analyzed over a 12-month period in the University of Virginia NICU, using the default averaging time (8 seconds) and SpO2 alarm limits set at 88-95% for infants on supplemental oxygen...
November 9, 2016: Journal of Neonatal-perinatal Medicine
https://www.readbyqxmd.com/read/27589555/anterior-placenta-previa-is-associated-with-increased-umbilical-cord-blood-hematocrit-concenrations
#6
K Daglar, A Tokmak, A Kirbas, O Kara, E Biberoglu, D Uygur, N Danisman
OBJECTIVE: We aimed to evaluate the umbilical cord blood (CB) hematocrit (Hct) levels in women with anterior located placenta previa (PP). METHODS: This is a prospective case-control study performed in a tertiary level maternity hospital. Thirty seven pregnant women diagnosed with anterior PP (study group) and 37 women without PP (control group) included into the study. Groups were matched with regard to age, gestational age, and fetal gender. All women underwent Cesarean section...
September 16, 2016: Journal of Neonatal-perinatal Medicine
https://www.readbyqxmd.com/read/27589554/morbidity-and-mortality-associated-with%C3%A2-rewarming-hypothermic-very-low-birth%C3%A2-weight%C3%A2-infants
#7
A Feldman, B De Benedictis, Gad Alpan, E F La Gamma, J Kase
OBJECTIVES: In very low birthweight (VLBW) infants, hypothermia is associated with poor outcomes. The goal of this study is to assess the relationship between the rate of rewarming these babies and their outcomes. METHODS: This is a retrospective cohort study of 98 inborn VLBW infants who were hypothermic (<36°C rectally) upon admission to the NICU. A logistic regression model was used to examine the relationship between the rates of rewarming and time to achieve euthermia and the following outcomes: death, intraventricular hemorrhage, severe intraventricular hemorrhage, bronchopulmonary dysplasia, necrotizing enterocolitis and retinopathy of prematurity...
September 16, 2016: Journal of Neonatal-perinatal Medicine
https://www.readbyqxmd.com/read/27589553/neonatal-care-what-do-mothers-in-a-rural-nigerian-community-know-and-practice
#8
C C Nnebue, C B Duru, K A Uwakwe, C O Ifeadike, B C Anyanwu, K M Adinnu, P O Nwaneri, I J Ufoh
BACKGROUND: Nigeria ranks among developing countries with poor neonatal health indices. This underscores the need for households and healthcare providers to understand the concept of newborn care and react appropriately and timely too. OBJECTIVE: To determine the knowledge and practices of mothers in the Elele community regarding neonatal care. MATERIALS AND METHODS: This was a community-based descriptive cross sectional study of 380 mothers who had a neonate...
September 16, 2016: Journal of Neonatal-perinatal Medicine
https://www.readbyqxmd.com/read/27589552/maternal-variables-associated-with-physiologic-stress-and-perinatal-complications-in-preterm-infants
#9
Tamara R Dietze, F F Rose, T A Moore
OBJECTIVE: Complications of prematurity may be related to dysregulation of the hypothalamic-pituitary-adrenal axis in preterm infants. Increased intrauterine exposure to cortisol may be responsible for adverse prenatal programming and subsequent dysfunction of the infant's hypothalamic-pituitary-adrenal axis. The aim of the study was to describe maternal social variables and their association with infant cortisol levels and complications of prematurity. METHODS: Preterm infants <32 weeks' gestation were recruited...
September 16, 2016: Journal of Neonatal-perinatal Medicine
https://www.readbyqxmd.com/read/27589551/an-international-survey-on-persistent-pulmonary-hypertension-of-the-newborn-a-need-for-an-evidence-based-management
#10
N Nakwan, P Chaiwiriyawong
OBJECTIVE: To assess the current practice preferences in diagnosis and management of persistent hypertension of the newborn (PPHN) of neonatologists or pediatricians with expertise in neonatal care. STUDY DESIGN: Investigators identified potential participants worldwide through a literature search. They were emailed the URL of an online 25-item questionnaire through the web survey site SurveyMonkey®. Additional respondents were also acquired through a professional online discussion group...
September 16, 2016: Journal of Neonatal-perinatal Medicine
https://www.readbyqxmd.com/read/27589550/cord-blood-lead-level-in-an-urban-inner-city-hospital
#11
S Chawla, F Elbakoush, G Natarajan, M Dwaihy, A Berry, Y Ravindranath, K Bhambhani, S B Narayan
Lead levels were measured by inductively coupled plasma mass spectrometry (ICP-MS) in umbilical cord blood samples of 150 neonates in an urban inner-city hospital. The mean (SD) gestation and birth weight of our cohort were 38.8 (1.7) weeks and 3,217 (519) grams. There were 89% African-Americans, 53% males and 79% were born via vaginal delivery. Mean (SD) maternal age was 24.5 (5.8) years. History of drug abuse and smoking was reported in 8.7% and 10.7% respectively, with only 1 mother reporting a history of high lead level in childhood...
September 16, 2016: Journal of Neonatal-perinatal Medicine
https://www.readbyqxmd.com/read/27589549/necrotizing-enterocolitis-in-premature-infants-and-newborns
#12
M J Mϋller, T Paul, S Seeliger
Necrotizing enterocolitis (NEC) is the most common acquired disease of the gastrointestinal tract (GIT) in premature infants and newborns. It is defined as an ulcerative inflammation of the intestinal wall. The clinical signs of incipient NEC are often very discrete, and range from localized intestinal symptoms to generalized signs of sepsis. NEC is classified depending on its severity into disease states according to the modified Bell's Classification. Treatment of NEC ranges, depending on its severity, from a conservative therapeutic approach to surgery with resection of the affected parts of the intestine...
September 16, 2016: Journal of Neonatal-perinatal Medicine
https://www.readbyqxmd.com/read/27589548/preterm-infant-body-composition-cannot-be-accurately-determined-by-weight-and-length
#13
J R Kiger, S N Taylor, C L Wagner, C Finch, L Katikaneni
BACKGROUND: Body composition is a key metric for assessing nutrition in preterm infants. In many neonatal intensive care units body composition is estimated using anthropometric indices which mathematically combine body weight and length. However, the accuracy of these indices is unknown in preterm infants. In contrast, air-displacement plethysmography (ADP) has been shown to accurately measure neonatal fat mass, but it is not widely available. OBJECTIVE: The aim was to determine which anthropometric index is most correlated to infant fat mass, as determined by ADP...
September 16, 2016: Journal of Neonatal-perinatal Medicine
https://www.readbyqxmd.com/read/27589547/hemodynamic-consequences-of-a-restrictive-ductus-arteriosus-and-foramen-ovale-in-fetal-transposition-of-the-great-arteries
#14
L Talemal, M T Donofrio
D-transposition of the great arteries (D-TGA) is the most commonly diagnosed cyanotic congenital heart disease presenting in the neonatal period. The survival after an arterial switch operation, with freedom from adverse cardiovascular events, has been reported to be as high as 93% at 25 years. However, despite excellent surgical outcomes, there continues to be significant preoperative morbidity and potential mortality due to compromise in the delivery room from foramen ovale closure requiring urgent balloon atrial septostomy for stabilization in the first minutes of life...
September 16, 2016: Journal of Neonatal-perinatal Medicine
https://www.readbyqxmd.com/read/27589546/neonatal-listeriosis-uncommon-or%C3%A2-misdiagnosed
#15
R I Kylat, A Bartholomew, N Cramer, M Y Bader
The incidence of perinatal and neonatal Listeriosis is underestimated due undiagnosed stillbirths, misdiagnosis of NL and underreporting of single case reports. Recent outbreaks reinforce the need for better surveillance and targeted health education in certain population groups especially during pregnancy.
September 16, 2016: Journal of Neonatal-perinatal Medicine
https://www.readbyqxmd.com/read/27589545/extensive-use-of-vasodilator-agents-and-functional-echocardiography-to-monitor-extremely-low-birth-weight-infants-in-japan
#16
M Miyata, K Toyoshima, H Yoda, M Murase, H Kawato, K Yamamoto, K Tanaka, M Kotani, M Kobayashi
National surveys were conducted in Japan to assess the current practices for circulatory management of extremely-low-birth-weight infants (ELBWIs) in acute phases. Approximately 80 and 100 institutions were surveyed in 2006 and 2011, respectively. Echocardiography was identified as an important diagnostic tool at 95% of the surveyed institutions. Furthermore, 74% of the institutions survey in 2011 used vasodilator agents. In 2011, the mean velocity of circumferential fiber shortening (mVcfc) and left ventricular end-systolic wall stress (ESWS) were used by 60% of the surveyed institutions to evaluate the relationship between afterload of the left ventricle and left ventricular contractility...
September 16, 2016: Journal of Neonatal-perinatal Medicine
https://www.readbyqxmd.com/read/27589544/use-of-uterine-artery-embolization-to%C3%A2-prevent-peripartum-hemorrhage-of-placental-abruption-with-fetal-demise-severe-dic
#17
E Latif, S Adam, B Rungruang, A Al-Hendy, M P Diamond, E Rotem, J Cannell, P C Browne
Uterine artery embolization (UAE) is typically not indicated in the pre-operative management of pregnancies with a live fetus, because risk of fetal death from reduced uteroplacental blood flow. However, pre-operative UAE in pregnancies with a fetal demise poses no fetal risk, and may offer maternal benefits. Patients with placental abruption resulting in fetal demise are at high-risk for developing disseminated intravascular coagulation (DIC), which could have devastating complications such as peri-operative hemorrhage and death...
September 16, 2016: Journal of Neonatal-perinatal Medicine
https://www.readbyqxmd.com/read/27589543/retained-surfactant-catheter-and%C3%A2-pneumothorax-in-a-premature-neonate
#18
J M Ismawan, C Abdallah
Surfactant catheters are used to administer exogenous surfactant as a preventive and therapeutic measure for surfactant deficiency in premature neonates. We describe the case of a retained surfactant catheter in a 700 g premature neonate with associated pneumothorax.
September 16, 2016: Journal of Neonatal-perinatal Medicine
https://www.readbyqxmd.com/read/27589542/effect-of-early-adjunctive-use-of-oral-sildenafil-and-inhaled-nitric-oxide-on-the-outcome-of-pulmonary-hypertension-in-newborn-infants-a-feasibility-study
#19
S Al Omar, H Salama, M Al Hail, H Al Rifai, M Bunahia, W El Kasem, F J Siddiqui, M Dilawar, H Yassin, F Masud, A Mohamed, A Mansour
INTRODUCTION: Inhaled nitric oxide (iNO) is the standard therapy for infants with persistent pulmonary hypertension of the newborn (PPHN). Recently, sildenafil has been evaluated as an alternative or adjunctive pulmonary vasodilator. OBJECTIVE: To assess the effectiveness of adding sildenafil as an early adjunctive therapy together with iNO when treating newborns with PPHN and/or hypoxemic respiratory failure. METHODS: This is a randomized placebo trial on newborns with gestational age > 34 weeks, postnatal age < 48 hours, and diagnosed with PPHN (oxygen index (OI) ≥ 20)...
September 16, 2016: Journal of Neonatal-perinatal Medicine
https://www.readbyqxmd.com/read/27341282/effects-of-parenteral-phosphorus-dose-restriction-in-preterm-infants
#20
K McNelis, S Viswanathan
BACKGROUND: In response to a national shortage of parenteral phosphorus solutions (2013), a hospital-wide phosphorus dose restriction strategies was implemented which included judicious use of phosphorus in preterm infants <1250 g birth weight and no parenteral phosphorus in preterm infants >1250 g birth weight unless they have a critically low phosphorus level. OBJECTIVE: To study the effect of parenteral phosphorus dose restriction in preterm infants admitted to the neonatal intensive care unit...
June 22, 2016: Journal of Neonatal-perinatal Medicine
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