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International Journal of Biomedical Science: IJBS

Mojtaba Ahmadinejad, Koorosh Ahmadi, Izadmehr Ahmadinejad, Amir Masoud Hashemian, Peyman Khademhoseini
BACKGROUND AND OBJECTIVES: Pilonidal sinus is a disease in the sacrococcygeal region diagnosed through the purulent discharges of the above-said region. Although the exact pathology and etiology of those suffering from pilonidal is not clear yet, the presence of hair seemingly plays a major role in the process of infection and the granulation tissue. Several techniques have been identified for pilonidal surgery. These techniques primarily fall within two categories: Primary repair and Lay open...
December 2016: International Journal of Biomedical Science: IJBS
Adel Johari Moghadam, Saied Azizinejad
INTRODUCTION: Although cardiac rehabilitation is known as a tool to reduce the overall risk of cardiovascular complications, its specific role in the reduction of hs-CRP as a marker of inflammation and a proven marker of cardiovascular risk needs further investigation. AIM: The present study aims at elucidating the effects of a full course of conventional cardiac rehabilitation program for the period of eight weeks, on the levels of hs-CRP in patients who underwent isolated coronary artery bypass surgery...
December 2016: International Journal of Biomedical Science: IJBS
Hilal S Mohammed, Sumeet Singh, Prasad A Hari, G S Amarnath, Vinaya Kundapur, Naveed Pasha, M Anand
BACKGROUND AND OBJECTIVE: Chemical cleansing by denture cleansers is first choice for denture plaque control. The most common problems while using denture cleansers are hardening, porosity, odor sorption, water sorption, solubility, and colour change, bacterial and fungal growth. Chemical cleansing procedures have been found to have an effect on the physical and mechanical properties of denture liners. Thus, this study was conducted to evaluate the effect of commercially available denture cleansers on surface hardness and roughness of acrylic and silicon based denture liners at various time interval...
December 2016: International Journal of Biomedical Science: IJBS
Mahmood Akbaryan, Farideh Darabi, Zahra Soltani
Dermatomyositis is an idiopathic inflammatory myopathy that cause skin and muscle complications. The ethiology is not understood well yet. Released cytokines including interferon and interleukins are suggested to make inflammatory responses in the skin or muscle. Muscle weakness and skin lesions including heliotrope rash, shawl sign and Gottron's papules are the most common symptoms. A biopsy (muscle or skin) is always the most reliable method for diagnosis. Corticosteroids in association with immunosuppressive agents are used as standard treatment...
December 2016: International Journal of Biomedical Science: IJBS
Azamsadat Mousavi, Mojgan Karimi-Zarchi, Nadere Behtash, Mitra Modares-Gilani, Mahnaz Mokhtari-Gorgani, Nili Mehrdad, Mitra Rouhi, Pouria Yazdian Anari
BACKGROUND: Epithelial ovarian cancer is the leading cause of death from gynecology malignancy. The aim of this study was to assess the role of intraperitoneal chemotherapy with carboplatin, as a consolidative treatment, in reducing relapse and increasing survival of patients in advanced epithelial ovarian cancers, as well as evaluation of its toxicity. METHODS: This clinical trial was conducted on 30 patients with epithelial ovarian cancer in stages II-IV in Gynecology oncology department in Valiasr University Hospital, Tehran during 2005-2010...
December 2016: International Journal of Biomedical Science: IJBS
Motahare Pilevarzadeh
Breast cancer is the most prevalent cancer among Iranian women. Early diagnosis of the disease is vitally important in successful treating of it and reducing its mortality and care-cost burden. In our country, the major causes of mortality and other unfavorable complications of the disease are due to late referring of women. Breast Self -Examination (BSE) is a low-cost, low-risk, self-performed screening, which, according to the evidence from the literature improves the prospects for women's survival. A content analysis with a qualitative approach was conducted in depth on women through semi-structured (individual and group) interviews...
September 2016: International Journal of Biomedical Science: IJBS
Ehsan Bolvardi, Seyyed Mohsen Pouryaghobi, Roohye Farzane, Niaz Mohamad Jafari Chokan, Koorosh Ahmadi, Hamidreza Reihani
Cardiopulmonary arrest is the final result of many diseases and therefore, need for a careful implementation of cardiopulmonary resuscitation (CPR) protocols in these cases is undeniably important. The introduction of ultrasound into the emergency department has potentially allowed the addition of an extra data point in the decision about when to cease cardiopulmonary resuscitation (CPR). The aim of this study is to evaluate the ability of cardiac ultrasonography performed by emergency physicians to predict resuscitation outcome in adult cardiac arrest patients...
September 2016: International Journal of Biomedical Science: IJBS
M Karimi-Zarchi, M Zaid Abadinezhad, B Bonyadpour, S Kabyrpour-Ashkezar, A M Abhaji
BACKGROUND AND AIM: Abnormal uterine bleeding is one of the most common debilitating menstrual problems. The first therapeutic strategy for abnormal uterine bleeding is drug treatment. This study was, therefore, designed to determine the efficacy of megestrol, medroxyprogesterone, GnRh agonist, Levonorgestrol IUD and endometrial ablation on bleeding and also to evaluate the side effects of each methods in patients with menorrhagia who were admitted to the Shahid Sadoughi clinic of Yazd University of Medical Sciences...
September 2016: International Journal of Biomedical Science: IJBS
Ashraf Galal, Fatina I Fadel, Enas Mokhtar, Manal F Elshamaa, Eman A Elghoroury, Solaf Kamel, Gamila S M Elsaeed, Eman H Thabet
BACKGROUND AND OBJECTIVES: Data concerning the concentration of matrix metalloproteinase-9 (MMP-9) and its functional polymorphisms in chronic kidney diseases (CKD) are conflicting. The present study aimed to evaluate the levels of MMP-9in children with end stage renal diseases (ESRD) on hemodialysis (HD) and to explore its association with MMP-9 polymorphism and vitamin D levels as an important risk factors for cardiovascular diseases (CVD). METHODS: We studied 55 children with ESRD on hemodialysis and 18 healthy children served as controls...
September 2016: International Journal of Biomedical Science: IJBS
Mahsa Asheghan, Mohammad Taghi Hollisaz, Abbas Shahabi Aghdam, Amidoddin Khatibiaghda
The aim of conducting this study was to determine the prevalence of PTS among patients with carpal tunnel syndrome. The study was conducted from March 2014 to April 2015 in the EDX ward and clinic of physical medicine and rehabilitation at the university hospital; Baqiytallah, a large referral practice and research center in Tehran. We included patients with clinical symptoms and signs of CTS. Clinical assessments were aimed to the diagnosis of CTS and PTS. At the next stage, ultrasound study was performed for the participants with suspected CTS...
September 2016: International Journal of Biomedical Science: IJBS
Brandon Li
Clostridium difficile is a major cause of nosocomial antibiotic-associated infectious diarrhea and pseudomembranous colitis. Detection of C. difficile by anaerobic bacterial culture and/or cytotoxicity assays has been largely replaced by rapid enzyme immunoassays (EIA). However, due to the lack of sensitivity of stool EIA, we developed a multiplex real-time PCR assay targeting the C. difficile toxin genes tcdB. stool samples from hospitalized pediatric patients suspected of having C. difficile-associated disease were prospectively collected...
September 2016: International Journal of Biomedical Science: IJBS
Killol V Pandya, ShivPrasad Kosta
Biomedical research is contributing significant role in the field of biomedical engineering and applied science. It brings research and innovations to a different level. This study investigated artificial human blood -synthetic plasma liquid as conductive medium. Keeping in mind the conductivity of synthetic plasma, astable multivibrator as well as differential amplifier circuit were demonstrated. The circuits were given normal input voltages at regular temperature and ideal conditions. The result shows desired response which supports the novel concept...
September 2016: International Journal of Biomedical Science: IJBS
L S El-Hosseiny, N N Alqurashy, S A Sheweita
Clinical studies have shown that several classes of antibiotics are evidenced in drug induced liver injury. The combination of amoxicillin with clavulanic acid is commonly cited in such cases. Accordingly, the present study investigated the potential hepatoprotective and in vivo antioxidant efficacy of sage essential oil in Co-amoxiclav induced hepatotoxicity in rats. Sage essential oil was hydrodistilled from the aerial parts of Salvia officinalis L. and its compositional analysis was characterized by Gas chromatography-Mass spectroscopy...
June 2016: International Journal of Biomedical Science: IJBS
Abolfazl Mohammadbeigi, Farzaneh Valizadeh, Seyede Roqaie Mirshojaee, Robabeh Ahmadli, Mohsen Mokhtari, Ebrahim Ghaderi, Ali Ahmadi, Heshmatollah Rezaei, Hossein Ansari
INTRODUCTION: Self-rated health is a brief measure for general health. It is a comprehensive and sensitive index for prediction of health in future. Due to the high internet usage in medical students, the current study designed to evaluate the self-rated health (SRH) in relationship with internet addiction risk factors in medical students. METHODS: This cross sectional study conducted on 254 students of Qom University of Medical Sciences 2014. Participants selected by two stage sampling method including stratified and simple random sampling...
June 2016: International Journal of Biomedical Science: IJBS
Shamir O Cawich, Michael T Gardner, Ramnanand Shetty, Neil W Pearce, Vijay Naraynsingh
INTRODUCTION: There have been no previous reports on the anatomic variations that exist on inferior surface of the liver in Caribbean populations. This information is important to optimize radiology and hepatobiliary surgical services in the region. METHODS: Two investigators independently observed 69 cadaveric dissections over five years and described the variations in surface anatomy. RESULTS: In this population 88% of cadaveric livers had conventional hepatic surface anatomy...
June 2016: International Journal of Biomedical Science: IJBS
Eda Guadalupe Ramirez-Valles, Verónica Dayali Gutierrez-Martinez, Maribel Cervantes-Flores, Estela Ruiz-Baca, Cosme Alvarado-Esquivel
T cells are components of adaptive immunity and are involved in the resolution of respiratory infections, which are a major cause of morbidity and mortality in young children worldwide. Activation and differentiation of T cells is given mostly by the cytokine IL-2. This study aimed to determine the phenotype of T cells and IL-2 expression in children suffering from upper respiratory tract infection with Streptococcus pyogenes (S. pyogenes). For this purpose, IL-2 expression at its gene and protein levels and quantitation of CD4(+) and CD8(+) T lymphocytes were assessed in children aged 0-5 years old suffering from upper respiratory tract infection with S...
June 2016: International Journal of Biomedical Science: IJBS
Cosme Alvarado-Esquivel, Luis Francisco Sánchez-Anguiano, Jesús Hernández-Tinoco, Agar Ramos-Nevárez, Sandra Margarita Cerrillo-Soto, Carlos Alberto Guido-Arreola
The seroepidemiology of Leptospira infection in patients suffering from liver disease has been poorly studied. Information about risk factors associated with infection in liver disease patients may help in the optimal planning of preventive measures. We sought to determine the association of Leptospira IgG seroprevalence and patients with liver diseases, and to determine the characteristics of the patients with Leptospira exposure. We performed a case-control study of 75 patients suffering from liver diseases and 150 age- and gender-matched control subjects...
June 2016: International Journal of Biomedical Science: IJBS
Samir M Abdel-Mageed, Ehab I Mohamed
Determining basal metabolic rate (BMR) is important for estimating total energy needs in the human being yet, concerns have been raised regarding the suitability of sex-specific equations based on age and weight for its calculation on an individual or population basis. It has been shown that body cell mass (BCM) is the body compartment responsible for BMR. The objectives of this study were to investigate the relationship between total body capacitance (TBC), which is considered as an expression for BCM, and BMR and to develop a formula for calculating BMR in comparison with widely used equations...
March 2016: International Journal of Biomedical Science: IJBS
Cosme Alvarado-Esquivel, Antonio Sifuentes-Alvarez, Carlos Salas-Martinez
Depression during pregnancy has been scantily studied in Mexican women. We aimed to determine the prevalence and correlates of depression in adult pregnant women attending a public hospital in the northern Mexican city of Durango, Mexico. Through a cross-sectional study design, we assessed depression in 270 adult pregnant women attended for prenatal care in a public hospital using a validated Mexican version of the Edinburg Postnatal Depression Scale in pregnancy and further confirmation by a psychiatric evaluation using the DSM-IV criteria for depression...
March 2016: International Journal of Biomedical Science: IJBS
Debipriya Banerjee, Sahana Mazumder, Asru Kumar Sinha
Platelet aggregation by different aggregating agonists is essential in the normal blood coagulation process, the excess of which caused acute coronary syndrome (ACS). In all cases, the activation of arachidonic acid by cycloxygenase was needed for the synthesis of thromboxane A2 (TXA2) but the mechanism of arachidonic acid release in platelets remains obscure. Studies were conducted to determine the role of nitric oxide (NO), if any, on the release of arachidonic acid in platelets. The cytosolic Ca(2+) was visualized and quantitated by fluorescent spectroscopy by using QUIN-2...
March 2016: International Journal of Biomedical Science: IJBS
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