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International Journal of Biomedical Science: IJBS

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https://www.readbyqxmd.com/read/28533736/telescopic-overdenture-a-case-report
#1
C S Shruthi, R Poojya, Swati Ram, Anupama
PATIENT: This report describes the case of a 68 year old female patient who presented with the chief complaint of difficulty in chewing and poor aesthetics due to missing teeth. The patient was interested in saving the remaining natural teeth and desired minimal tissue coverage from the prosthesis. After consideration of all the factors involved, it was deemed advisable to resort to a palate free maxillary telescopic complete denture and a mandibular removable partial denture. DISCUSSION: Considering the age of the patient and the cost involved, implant supported prosthesis was ruled out as a treatment option for the patient...
March 2017: International Journal of Biomedical Science: IJBS
https://www.readbyqxmd.com/read/28533735/esm-1-sirna-knockdown-decreased-migration-and-expression-of-cxcl3-in-prostate-cancer-cells
#2
Juan Rebollo, Jan Geliebter, Niradiz Reyes
Endothelial cell-specific molecule-1 (ESM-1), also known as endocan, is a soluble proteoglycan expressed by the vascular endothelium, which also circulates in the bloodstream. Inflammatory cytokines and proangiogenic growth factors increase its expression, and increased serum levels have been reported in several cancer types and immunocompetent patients with sepsis. The aim of this study was to analyze the expression profile of CXC-chemokines and the effects of ESM-1 gene knockdown in proliferation, migration and CXC-chemokine expression in highly metastatic human prostate PC-3 cells...
March 2017: International Journal of Biomedical Science: IJBS
https://www.readbyqxmd.com/read/28533734/gene-expression-profiling-associated-with-hepatoxicity-in-pregnant-rats-treated-with-ubi-gadong-dioscorea-hispida-extract
#3
Ezarul Faradianna Lokman, Hussin Muhammad, Norizah Awang, Maizatul Hasyima Omar, Fazliana Mansor, Fatin Saparuddin
Dioscorea hispida (D.hispida) is the most well-known starchy tuber in Malaysia and called 'ubi gadong'. Despite concerns over toxicity effects, the tuber is known to possess therapeutic values due to the presence of bioactive compounds such as saponins. This study was performed to identify the changes in gene expression profiles associated with hepatoxicity in pregnant rat treated with D.hispida using RT² Profiler PCR Array. The identification of steroidal saponins from D.hispida was carried out by UHPLC/MS method...
March 2017: International Journal of Biomedical Science: IJBS
https://www.readbyqxmd.com/read/28533733/tobacco-smoke-exposure-reduces-paraoxonase-activity-in-a-murine-model
#4
Robert M Reed, Saif M Borgan, Michael Eberlein, Monica Goldklang, Joshua Lewis, Michael Miller, Mohamad Navab, Bo S Kim
AIM: To demonstrate a direct inhibitory effect of cigarette smoke exposure on paraoxonase 1 activity in a murine in vivo model. METHODS: At 8 weeks old, we randomized 10 C57/bl6 mice to an environment consisting of either filtered air or cigarette smoke for 6 months. Smoke exposure (7 hours per day, 5 days per week) was standardized using a model TE-10 smoking machine and adjusted to maintain constant sidestream and mainstream smoke. After 6 months of exposure, we assessed differences in lung air space, cholesterol, lipid, and lipoprotein profiles, as well as paraoxonase activity in mice exposed to cigarette smoke extract compared to unexposed control mice...
March 2017: International Journal of Biomedical Science: IJBS
https://www.readbyqxmd.com/read/28533732/e-cadherin-and-fgfr1-expression-in-mouse-osteoblastogenesis-in-normoxic-cultures
#5
Osama Al-Amer
E-cadherin is a cell surface adhesion molecules that play an important role in tissue differentiation. FGFR1 is expressed in the developing and mature skeleton in patterns suggestive of both unique and redundant function. Expression levels of E-cadherin and FGFR1 during osteoblastogenesis unclear. In this study primary calvarial mouse osteoblasts were differentiated to mature osteoblasts in osteogenic medium. Alkaline phosphatase (ALP) activity, alizarin red staining, gene expression (Runt-related transcription factor 2 (Runx2), collagen 1 (COL1A2), osteocalcin, E-cadherin and FGFR1) and protein expression (E-cadherin and FGFR1) of osteogenic-cultured primary mouse osteoblast were analysed in this study...
March 2017: International Journal of Biomedical Science: IJBS
https://www.readbyqxmd.com/read/28533731/effect-of-loss-of-teeth-and-its-association-with-general-quality-of-life-using-geriatric-oral-health-assessment-index-gohai-among-older-individuals-residing-in-rural-areas
#6
Vinaya Kundapur, Rakshith Hegde, Manoj Shetty, Sunil Mankar, Mohammed Hilal, Hari Prasad A
The development of measures for assessing oral health status is essential to the evolution and maturation of a scientific knowledge based in geriatric dentistry. Their development as branches of clinical care depends in part as ability to demonstrate an effective grasp of the problems of elderly and their solutions. Any strategy for altering the health status of elderly requires a technology for first assessing that health status and then detecting increments of progress. Development of geriatric oral health assessment index (GOHAI) is a self reported measure designed to assess the oral health problems of older individuals...
March 2017: International Journal of Biomedical Science: IJBS
https://www.readbyqxmd.com/read/28533730/forensic-odontology-the-new-dimension-in-dental-analysis
#7
K P Divakar
Forensic Odontology a branch of Forensic sciences uses the skill of the dentist in personal identification during mass calamities, sexual assault and child abuse to name a few. This branch not stranger to many has been growing tenfold in its potential and its ability to bring the forlorn to justice where a dental remains is the only available evidence. It's role and importance in the judiciary is fast growing and hence in depth knowledge in this field seems more than justified.
March 2017: International Journal of Biomedical Science: IJBS
https://www.readbyqxmd.com/read/28190985/a-comparison-between-the-tie-over-and-closed-suction-drainage-therapeutic-strategies-in-patients-suffering-from-sacral-pilonidal-sinus
#8
Mojtaba Ahmadinejad, Koorosh Ahmadi, Izadmehr Ahmadinejad, Amir Masoud Hashemian, Peyman Khademhoseini
BACKGROUND AND OBJECTIVES: Pilonidal sinus is a disease in the sacrococcygeal region diagnosed through the purulent discharges of the above-said region. Although the exact pathology and etiology of those suffering from pilonidal is not clear yet, the presence of hair seemingly plays a major role in the process of infection and the granulation tissue. Several techniques have been identified for pilonidal surgery. These techniques primarily fall within two categories: Primary repair and Lay open...
December 2016: International Journal of Biomedical Science: IJBS
https://www.readbyqxmd.com/read/28190984/study-of-high-sensitive-c-reactive-protein-hs-crp-after-cardiac-rehabilitation-program-in-patients-undergoing-isolated-cabg
#9
Adel Johari Moghadam, Saied Azizinejad
INTRODUCTION: Although cardiac rehabilitation is known as a tool to reduce the overall risk of cardiovascular complications, its specific role in the reduction of hs-CRP as a marker of inflammation and a proven marker of cardiovascular risk needs further investigation. AIM: The present study aims at elucidating the effects of a full course of conventional cardiac rehabilitation program for the period of eight weeks, on the levels of hs-CRP in patients who underwent isolated coronary artery bypass surgery...
December 2016: International Journal of Biomedical Science: IJBS
https://www.readbyqxmd.com/read/28190983/evaluate-the-effect-of-commercially-available-denture-cleansers-on-surface-hardness-and-roughness-of-denture-liners-at-various-time-intervals
#10
Hilal S Mohammed, Sumeet Singh, Prasad A Hari, G S Amarnath, Vinaya Kundapur, Naveed Pasha, M Anand
BACKGROUND AND OBJECTIVE: Chemical cleansing by denture cleansers is first choice for denture plaque control. The most common problems while using denture cleansers are hardening, porosity, odor sorption, water sorption, solubility, and colour change, bacterial and fungal growth. Chemical cleansing procedures have been found to have an effect on the physical and mechanical properties of denture liners. Thus, this study was conducted to evaluate the effect of commercially available denture cleansers on surface hardness and roughness of acrylic and silicon based denture liners at various time interval...
December 2016: International Journal of Biomedical Science: IJBS
https://www.readbyqxmd.com/read/28190982/dermatomyositis-leading-to-necrotizing-vasculitis-a-perfect-response-to-applied-therapy
#11
Mahmood Akbaryan, Farideh Darabi, Zahra Soltani
Dermatomyositis is an idiopathic inflammatory myopathy that cause skin and muscle complications. The ethiology is not understood well yet. Released cytokines including interferon and interleukins are suggested to make inflammatory responses in the skin or muscle. Muscle weakness and skin lesions including heliotrope rash, shawl sign and Gottron's papules are the most common symptoms. A biopsy (muscle or skin) is always the most reliable method for diagnosis. Corticosteroids in association with immunosuppressive agents are used as standard treatment...
December 2016: International Journal of Biomedical Science: IJBS
https://www.readbyqxmd.com/read/28190981/the-role-of-intraperitoneal-carboplatin-as-consalidation-chemotherapy-in-women-with-ovarian-carcinoma-report-of-our-experience-and-systematic-review
#12
Azamsadat Mousavi, Mojgan Karimi-Zarchi, Nadere Behtash, Mitra Modares-Gilani, Mahnaz Mokhtari-Gorgani, Nili Mehrdad, Mitra Rouhi, Pouria Yazdian Anari
BACKGROUND: Epithelial ovarian cancer is the leading cause of death from gynecology malignancy. The aim of this study was to assess the role of intraperitoneal chemotherapy with carboplatin, as a consolidative treatment, in reducing relapse and increasing survival of patients in advanced epithelial ovarian cancers, as well as evaluation of its toxicity. METHODS: This clinical trial was conducted on 30 patients with epithelial ovarian cancer in stages II-IV in Gynecology oncology department in Valiasr University Hospital, Tehran during 2005-2010...
December 2016: International Journal of Biomedical Science: IJBS
https://www.readbyqxmd.com/read/27829828/women-s-perspective-of-breast-self-examination
#13
Motahare Pilevarzadeh
Breast cancer is the most prevalent cancer among Iranian women. Early diagnosis of the disease is vitally important in successful treating of it and reducing its mortality and care-cost burden. In our country, the major causes of mortality and other unfavorable complications of the disease are due to late referring of women. Breast Self -Examination (BSE) is a low-cost, low-risk, self-performed screening, which, according to the evidence from the literature improves the prospects for women's survival. A content analysis with a qualitative approach was conducted in depth on women through semi-structured (individual and group) interviews...
September 2016: International Journal of Biomedical Science: IJBS
https://www.readbyqxmd.com/read/27829827/the-prognostic-value-of-using-ultrasonography-in-cardiac-resuscitation-of-patients-with-cardiac-arrest
#14
Ehsan Bolvardi, Seyyed Mohsen Pouryaghobi, Roohye Farzane, Niaz Mohamad Jafari Chokan, Koorosh Ahmadi, Hamidreza Reihani
Cardiopulmonary arrest is the final result of many diseases and therefore, need for a careful implementation of cardiopulmonary resuscitation (CPR) protocols in these cases is undeniably important. The introduction of ultrasound into the emergency department has potentially allowed the addition of an extra data point in the decision about when to cease cardiopulmonary resuscitation (CPR). The aim of this study is to evaluate the ability of cardiac ultrasonography performed by emergency physicians to predict resuscitation outcome in adult cardiac arrest patients...
September 2016: International Journal of Biomedical Science: IJBS
https://www.readbyqxmd.com/read/27829826/evaluate-the-effectiveness-of-conservative-treatment-for-menorrhagia-in-women-who-were-admitted-to-the-shahid-sadoughi-hospital-of-yazd-iran-in-2014-2015
#15
M Karimi-Zarchi, M Zaid Abadinezhad, B Bonyadpour, S Kabyrpour-Ashkezar, A M Abhaji
BACKGROUND AND AIM: Abnormal uterine bleeding is one of the most common debilitating menstrual problems. The first therapeutic strategy for abnormal uterine bleeding is drug treatment. This study was, therefore, designed to determine the efficacy of megestrol, medroxyprogesterone, GnRh agonist, Levonorgestrol IUD and endometrial ablation on bleeding and also to evaluate the side effects of each methods in patients with menorrhagia who were admitted to the Shahid Sadoughi clinic of Yazd University of Medical Sciences...
September 2016: International Journal of Biomedical Science: IJBS
https://www.readbyqxmd.com/read/27829825/matrix-metalloproteinase-mmp-9-levels-in-children-on-hemodialysis-association-with-mmp-9-c-1562-t-gene-polymorphism-and-vitamin-d-levels
#16
Ashraf Galal, Fatina I Fadel, Enas Mokhtar, Manal F Elshamaa, Eman A Elghoroury, Solaf Kamel, Gamila S M Elsaeed, Eman H Thabet
BACKGROUND AND OBJECTIVES: Data concerning the concentration of matrix metalloproteinase-9 (MMP-9) and its functional polymorphisms in chronic kidney diseases (CKD) are conflicting. The present study aimed to evaluate the levels of MMP-9in children with end stage renal diseases (ESRD) on hemodialysis (HD) and to explore its association with MMP-9 polymorphism and vitamin D levels as an important risk factors for cardiovascular diseases (CVD). METHODS: We studied 55 children with ESRD on hemodialysis and 18 healthy children served as controls...
September 2016: International Journal of Biomedical Science: IJBS
https://www.readbyqxmd.com/read/27829824/the-prevalence-of-pronator-teres-among-patients-with-carpal-tunnel-syndrome-cross-sectional-study
#17
Mahsa Asheghan, Mohammad Taghi Hollisaz, Abbas Shahabi Aghdam, Amidoddin Khatibiaghda
The aim of conducting this study was to determine the prevalence of PTS among patients with carpal tunnel syndrome. The study was conducted from March 2014 to April 2015 in the EDX ward and clinic of physical medicine and rehabilitation at the university hospital; Baqiytallah, a large referral practice and research center in Tehran. We included patients with clinical symptoms and signs of CTS. Clinical assessments were aimed to the diagnosis of CTS and PTS. At the next stage, ultrasound study was performed for the participants with suspected CTS...
September 2016: International Journal of Biomedical Science: IJBS
https://www.readbyqxmd.com/read/27829823/a-new-lab-developed-real-time-pcr-assay-for-direct-detection-of-c-difficle-from-stool-sample-without-dna-extraction
#18
Brandon Li
Clostridium difficile is a major cause of nosocomial antibiotic-associated infectious diarrhea and pseudomembranous colitis. Detection of C. difficile by anaerobic bacterial culture and/or cytotoxicity assays has been largely replaced by rapid enzyme immunoassays (EIA). However, due to the lack of sensitivity of stool EIA, we developed a multiplex real-time PCR assay targeting the C. difficile toxin genes tcdB. stool samples from hospitalized pediatric patients suspected of having C. difficile-associated disease were prospectively collected...
September 2016: International Journal of Biomedical Science: IJBS
https://www.readbyqxmd.com/read/27829822/synthetic-plasma-liquid-based-electronic-circuits-realization-a-novel-concept
#19
Killol V Pandya, ShivPrasad Kosta
Biomedical research is contributing significant role in the field of biomedical engineering and applied science. It brings research and innovations to a different level. This study investigated artificial human blood -synthetic plasma liquid as conductive medium. Keeping in mind the conductivity of synthetic plasma, astable multivibrator as well as differential amplifier circuit were demonstrated. The circuits were given normal input voltages at regular temperature and ideal conditions. The result shows desired response which supports the novel concept...
September 2016: International Journal of Biomedical Science: IJBS
https://www.readbyqxmd.com/read/27493593/oxidative-stress-alleviation-by-sage-essential-oil-in-co-amoxiclav-induced-hepatotoxicity-in-rats
#20
L S El-Hosseiny, N N Alqurashy, S A Sheweita
Clinical studies have shown that several classes of antibiotics are evidenced in drug induced liver injury. The combination of amoxicillin with clavulanic acid is commonly cited in such cases. Accordingly, the present study investigated the potential hepatoprotective and in vivo antioxidant efficacy of sage essential oil in Co-amoxiclav induced hepatotoxicity in rats. Sage essential oil was hydrodistilled from the aerial parts of Salvia officinalis L. and its compositional analysis was characterized by Gas chromatography-Mass spectroscopy...
June 2016: International Journal of Biomedical Science: IJBS
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