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Journal of Undergraduate Neuroscience Education: JUNE: a Publication of FUN, Faculty for Undergraduate Neuroscience

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https://www.readbyqxmd.com/read/30057514/introduction-to-the-hypothalamic-pituitary-adrenal-axis-healthy-and-dysregulated-stress-responses-developmental-stress-and-neurodegeneration
#1
Catherine J Dunlavey
Neurohormone systems, which regulate the maintenance of homeostasis and allostasis during stress, are a fundamental subject in the understanding of neuroendocrine function. One neuroendocrine system, the hypothalamic-pituitary-adrenal axis (HPA), is crucial for stress management. Study of the HPA-axis illustrates a mélange of interactions between different physiological systems to ensure survival, longevity, development and homeostatic maintenance. While some stress is important for healthy development, chronic stress has pathological consequences...
2018: Journal of Undergraduate Neuroscience Education: JUNE: a Publication of FUN, Faculty for Undergraduate Neuroscience
https://www.readbyqxmd.com/read/30057513/faces-in-the-brain-the-discovery-of-a-neuronal-subpopulation-selective-for-face-recognition
#2
James Febery
Facial recognition is a fundamental feature of primate social interaction. However, the location and number of neurons that are solely dedicated to the recognition of faces and facial features are not well known. The following mini review describes a paper by Perrett and colleagues that identifies and describes a subpopulation of neurons in the superior temporal sulcus that appear to be strongly tuned to faces and facial features. This paper holds great value for undergraduate teaching, as it is a foundational paper within the literature of face recognition...
2018: Journal of Undergraduate Neuroscience Education: JUNE: a Publication of FUN, Faculty for Undergraduate Neuroscience
https://www.readbyqxmd.com/read/30057512/reviewing-the-diverse-effects-of-protein-phosphorylation-in-neural-signaling-transduction
#3
Abby K Scurfield
Signaling transduction pathways are now known to be foundational mechanisms for a wide variety of biological function. Nobel laureate Paul Greengard dedicated his early career to the exploration of how these molecular cascades are triggered by neurotransmitters, hence applying a general phenomenon to the nervous system. A review by Hemmings, Nairn, McGuinness, Huganir, and Greengard published in the FASEB journal in 1989 identifies three different effects of protein phosphorylation, namely vesicle release, modulation of receptor sensitivity, and initiation of positive or negative feedback systems...
2018: Journal of Undergraduate Neuroscience Education: JUNE: a Publication of FUN, Faculty for Undergraduate Neuroscience
https://www.readbyqxmd.com/read/30057511/the-grasshopper-mouse-and-bark-scorpion-evolutionary-biology-meets-pain-modulation-and-selective-receptor-inactivation
#4
Benjamin M Thompson
Pain, however unpleasant, is a vital part of survival, providing a motivating response to noxious stimuli that helps move us away from danger. In medicine, adequate pain control can be maintained using analgesics, many of which produce unwanted and complicating side effects, most notably opioid analgesics. Here, I review a study which explored the unique predator/prey relationship between the Southern grasshopper mouse ( Onychomys torridus ) and its natural prey, the Arizona bark scorpion (C entruroides sculpturatus )...
2018: Journal of Undergraduate Neuroscience Education: JUNE: a Publication of FUN, Faculty for Undergraduate Neuroscience
https://www.readbyqxmd.com/read/30057510/one-brain-two-minds-many-questions
#5
Victoria Rosen
For several decades, split-brain research has provided valuable insight into the fields of psychology and neuroscience. These studies have progressed our knowledge of hemispheric specialization, language processing, the role of the corpus callosum, cognition, and even human consciousness. Following a recent empirical paper by Pinto et al. (2017a) and review by Volz and Gazzaniga (2017), a debate has ensued about the nature of conscious perception of visual stimuli in split-brain patients. This exchange is an ideal platform for generating discussion about both the implications of recent findings and the interpretation of results from split-brain studies in general...
2018: Journal of Undergraduate Neuroscience Education: JUNE: a Publication of FUN, Faculty for Undergraduate Neuroscience
https://www.readbyqxmd.com/read/30057509/constructing-an-inexpensive-elevated-plus-maze
#6
Grant A Fox, Eugene Torigoe, Greg Q Butcher
Introducing students to the challenges and rewards of legitimate experimentation has become an essential part of many undergraduate lab courses. However, this objective can be difficult to achieve if the students find the topic uninteresting and therefore do not take ownership of the project. Additionally, the budgets of most undergraduate courses do not allow for the purchase of new equipment for student-generated projects. Here we describe a lab project where students engaged in the process of designing and building their own inexpensive apparatus...
2018: Journal of Undergraduate Neuroscience Education: JUNE: a Publication of FUN, Faculty for Undergraduate Neuroscience
https://www.readbyqxmd.com/read/30057508/characteristics-emergent-properties-and-functions-of-somato-dendritic-t-and-l-type-calcium-channels
#7
Corey L Cleland
The primary literature, as an adjunct to textbooks, lectures, problem sets, and laboratories, has become integral to most undergraduate neuroscience courses by extending learning to topics outside the scope of introductory textbooks, providing insight into experimental methods and design, and offering a platform for critical thinking, independent learning, and student presentations. While introductory and intermediate textbooks cover "Hodgkin-Huxley" (H-H) Na and K channels thoroughly, the characteristics of diverse calcium, chloride, and other sodium and potassium channels, and especially the resulting emergent cellular properties and their functional consequences, receive far less coverage...
2018: Journal of Undergraduate Neuroscience Education: JUNE: a Publication of FUN, Faculty for Undergraduate Neuroscience
https://www.readbyqxmd.com/read/30057507/using-a-model-to-understand-the-symptoms-of-ophthalmoplegia
#8
Alexander J Wood, Manisha R Dayal
When the term muscular paralysis is used, most people will think of large muscle groups such as the upper and lower limbs or life-dependent muscles such as the diaphragm. However, the extrinsic extraocular muscles can also succumb to paralysis (whether partial or otherwise). Ophthalmoplegia can arise from a number of neural conditions, and in conjunction with the complex anatomy of the ocular orbit, it can be difficult to teach such syndromes. The range of existing physical models for the eye are limited in their functional ability, prohibiting the understanding of the structure and its function especially with regards to muscles...
2018: Journal of Undergraduate Neuroscience Education: JUNE: a Publication of FUN, Faculty for Undergraduate Neuroscience
https://www.readbyqxmd.com/read/30057506/on-the-application-of-multivariate-statistical-and-data-mining-analyses-to-data-in-neuroscience
#9
REVIEW
Paul F Smith
Research in neuroscience, whether at the level of genes, proteins, neurons or behavior, almost always involves the interaction of multiple variables, and yet many areas of neuroscience employ univariate statistical analyses almost exclusively. Since multiple variables often work together to produce a neuronal or behavioral effect, the use of univariate statistical procedures, analyzing one variable at a time, limits the ability of studies to reveal how interactions between different variables may determine a particular outcome...
2018: Journal of Undergraduate Neuroscience Education: JUNE: a Publication of FUN, Faculty for Undergraduate Neuroscience
https://www.readbyqxmd.com/read/30057505/active-learning-for-students-and-faculty
#10
EDITORIAL
Bruce R Johnson
No abstract text is available yet for this article.
2018: Journal of Undergraduate Neuroscience Education: JUNE: a Publication of FUN, Faculty for Undergraduate Neuroscience
https://www.readbyqxmd.com/read/30057504/teaching-neuroanatomy-through-a-historical-context
#11
Lorenz S Neuwirth, Teddy F Dacius, B Runi Mukherji
No abstract text is available yet for this article.
2018: Journal of Undergraduate Neuroscience Education: JUNE: a Publication of FUN, Faculty for Undergraduate Neuroscience
https://www.readbyqxmd.com/read/30057503/the-new-statistics-for-neuroscience-majors-thinking-in-effect-sizes
#12
Robert J Calin-Jageman
An ongoing reform in statistical practice is to report and interpret effect sizes. This paper provides a short tutorial on effect sizes and some tips on how to help your students think in terms of effect sizes when analyzing data. An effect size is just a quantitative answer to a research question. Effect sizes should always be accompanied by a confidence interval or some other means of expressing uncertainty in generalizing from the sample to the population. Effect sizes are best interpreted in raw scores, but can also be expressed in standardized terms; several popular standardized effect score measures are explained and compared...
2018: Journal of Undergraduate Neuroscience Education: JUNE: a Publication of FUN, Faculty for Undergraduate Neuroscience
https://www.readbyqxmd.com/read/30057502/epilepsy-and-the-action-potential-using-case-based-instruction-and-primary-literature-in-a-neurobiology-course
#13
Nikki T Sawyer, Kristen E Frenzel
Epilepsy and seizure generation are at the center of this case study narrative. By exploring the nature of genetic mutations in voltage-gated sodium channels students will solidify fundamental concepts involving action potential generation and roles for excitatory and inhibitory neurons in the central nervous system. Students will wrestle with primary data, developing analytical and quantitative skills, and generate evidence-based hypotheses and predictions. As written here, the case is used in an upper-level undergraduate course, but because the case focuses on basic fundamental neuroscience concepts, the narrative could be easily adapted for uses in introductory neuroscience courses or potentially first-year graduate courses...
2018: Journal of Undergraduate Neuroscience Education: JUNE: a Publication of FUN, Faculty for Undergraduate Neuroscience
https://www.readbyqxmd.com/read/30057501/using-imagej-to-assess-neurite-outgrowth-in-mammalian-cell-cultures-research-data-quantification-exercises-in-undergraduate-neuroscience-lab
#14
Kyle Pemberton, Brittany Mersman, Fenglian Xu
Brain functions rely critically upon the proper development of neuronal processes (axons and dendrites) and the formation of functional networks. Any genetic factors or environmental compounds that alter the morphological features of neurons may render the nervous system dysfunctional and result in neuronal disorders. In vitro cell culture is an important technique in assessing the effect of chemicals on neurite formation and growth of individual neurons in desired brain regions and has been fundamental in advancing our understanding of the nervous system development and functioning...
2018: Journal of Undergraduate Neuroscience Education: JUNE: a Publication of FUN, Faculty for Undergraduate Neuroscience
https://www.readbyqxmd.com/read/30057500/aversive-and-appetitive-learning-in-drosophila-larvae-a-simple-and-powerful-suite-of-laboratory-modules-for-classroom-or-open-ended-research-projects
#15
Austin Pavin, Kevin Fain, Allison DeHart, Divya Sitaraman
A key element of laboratory courses introducing students to neuroscience includes behavioral exercises. Associative learning experiments often conducted in research laboratories are difficult to perform and time consuming. Commonly, these experiments cannot be performed without extensive instrumentation or animal care facilities. Here, we describe three distinct laboratory modules that build on simple chemosensory and memory assays in Drosophila larvae. Additionally, we describe open-ended research projects using these assays that can be developed into semester long independent research experiences...
2018: Journal of Undergraduate Neuroscience Education: JUNE: a Publication of FUN, Faculty for Undergraduate Neuroscience
https://www.readbyqxmd.com/read/30057499/the-olfactory-proboscis-extension-response-in-the-honey-bee-a-laboratory-exercise-in-classical-conditioning
#16
Byron N Van Nest
The beginning neuroscience or psychology student does not often have the opportunity to experiment with classical conditioning. Here I present an inexpensive, easy-to-implement classical conditioning experiment taking advantage of the proboscis extension response to train honey bees to learn an appetitive olfactory association. If an apiary is available, this exercise can be implemented in large scale (training many animals simultaneously) with no specialized equipment so that students can train insects to recognize and respond to a specific odor within the time constraints of a single laboratory classroom session...
2018: Journal of Undergraduate Neuroscience Education: JUNE: a Publication of FUN, Faculty for Undergraduate Neuroscience
https://www.readbyqxmd.com/read/30057498/partnerships-in-neuroscience-research-between-small-colleges-and-large-institutions-a-case-study
#17
John G McCoy, Heather J Yu, Margaret Niznikiewicz, James T McKenna, Robert E Strecker
There are advantages and limitations associated with a science, technology, engineering and math (STEM) education at small, liberal arts colleges relative to larger universities. While there may be increased opportunity for personal attention and access to faculty, students at liberal arts colleges may not always have the opportunity to gain experience with state-of-the-art equipment and technology. Herein, we describe a case study of an inter-institutional partnership between Stonehill College and two neuroscience research laboratories which are part of the Veterans Affairs Boston Healthcare System (VABHS)...
2018: Journal of Undergraduate Neuroscience Education: JUNE: a Publication of FUN, Faculty for Undergraduate Neuroscience
https://www.readbyqxmd.com/read/30057497/using-optogenetics-to-understand-neuronal-mechanisms-underlying-behavior-in-c-elegans
#18
Navin Pokala, Elizabeth E Glater
Approaches for inhibiting and activating neurons are essential for understanding how neurons and neuronal circuits produce behavior. Optogenetics is a recently-developed technique which uses light to manipulate neuronal activity with temporal precision in behaving animals and is widely-used by neuroscience researchers . Optogenetics is also an excellent method to incorporate into an undergraduate neuroscience laboratory module because students can learn to conduct and analyze quantitative behavioral assays, reinforce their understanding of synaptic transmission, and investigate the genetic and neuronal basis of behavior...
2018: Journal of Undergraduate Neuroscience Education: JUNE: a Publication of FUN, Faculty for Undergraduate Neuroscience
https://www.readbyqxmd.com/read/30057496/a-low-cost-morris-water-maze-for-undergraduate-research-construction-and-demonstration-in-a-rat-model-of-obesity-induced-diabetes
#19
Lester Maxwell Gallivan, Neil Schmitzer-Torbert
The Morris Water Maze (MWM) is a standard task for assessing hippocampal-dependent learning and memory, but the cost of commercial versions of the task may be prohibitive for some undergraduate research projects. We describe the construction of a low-cost MWM for use with rodents and demonstrate the effectiveness of the MWM in a study of the effect of diet-induced obesity on cognitive function in rats. Previous studies have described an impairment in MWM performance in rats fed a high-fat diet combined with streptozotocin injection (to model Type 2 diabetes)...
2018: Journal of Undergraduate Neuroscience Education: JUNE: a Publication of FUN, Faculty for Undergraduate Neuroscience
https://www.readbyqxmd.com/read/30057495/the-design-implementation-and-assessment-of-an-undergraduate-neurobiology-course-using-a-project-based-approach
#20
Melissa Zwick
Project-based learning (PBL) is a student-centered approach that allows students to build on prior knowledge and address relevant problems while working on challenging projects. PBL is well-suited to undergraduate neuroscience courses because students are often interested in learning about diseased states of the nervous system, but can be discouraged by having to learn the chemical and cellular mechanisms underlying pathologies in a lecture-based learning environment. PBL provides students with a significant learning experience that excites them and can help them learn challenging content...
2018: Journal of Undergraduate Neuroscience Education: JUNE: a Publication of FUN, Faculty for Undergraduate Neuroscience
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