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Pakistan Journal of Medical Sciences Quarterly

Onur Ozturk, Fatih Ileri
Submission to journals takes a lot of time and format related submission requirements vary greatly from one journal to another. Lack of time and motivation in academia reduces scientific outputs and demotivates researchers. Author-based journal selection system (ABJSS) is a platform for pooling manuscripts conceived to minimize the time spent for manuscript submission and to increase scientific output. The system will provide two types of account: "Author" and "Journal Administrator". Each account type will have its own abilities and permissions...
January 2018: Pakistan Journal of Medical Sciences Quarterly
Syed Farrukh Umair, Imrana Amin, Ata Urrehman
The use of hair dye has been emerging worldwide however usage of Paraphenylenediamine (PPD) in making hair dye is generally restricted to underdeveloped and developing countries. In particular, prevalence of accidental and suicidal ingestion is more in low socioeconomic areas. The spectra of hair dye toxicity is wide, however, it presents more commonly with severe angioedema of face and neck leading to respiratory failure, rhabdomyolysis complicating into acute kidney injury, myocarditis and acute liver injury...
January 2018: Pakistan Journal of Medical Sciences Quarterly
Saba Zulfiqar, Fatma Hussain, Amer Jamil, Nisar Ahmed
Objectives: Type-2 diabetes mellitus (T2DM) is an endocrine disease having a significant genetic component. Polymorphisms of many genes may affect hereditary vulnerability of the disease that is characterized by insulin resistance and islet disorder. As the genetic basis of T2DM can vary between ethnic groups, it is important to investigate the genetic link of T2DM in Pakistani populace. This study was aimed to assess the association of receptor for advanced glycation end product (RAGE) gene polymorphism (-429T>C) with Type-2 diabetes mellitus within local populace...
January 2018: Pakistan Journal of Medical Sciences Quarterly
Syed Muhammad Faisal, Muhammad Ali Tahir, Alyscia Miriam Cheema, Muhammad Ijaz Anjum
Objective: To compare the success in patients having vitreous hemorrhage undergoing pars plana vitrectomy with or without preoperative intravitreal injection of Bevacizumab. Methods: This Randomized controlled trial was conducted at Department of Ophthalmology, Jinnah Postgraduate Medical Centre. Karachi. Duration of study was six months from January 2010 to June 2010. In this study 56 patients of advanced diabetic eye disease were divided into two groups. Patients in Group-A underwent three ports pars plana vitrectomy with preoperative intravitreal injection of Bevacizumab (Avastin) 1...
January 2018: Pakistan Journal of Medical Sciences Quarterly
Weidong Wang, Guanglei Li, Hongming Yang
Objective: Hypertrophic scar is common in burn patients, but treating result could not meet the expectation of the patients and doctors. We have found that certain concentration level of lipopolysaccharide (LPS) stimulated normal fibroblast cells have statistically similar with fibroblast cells from hypertrophic scar on the phenotype level, and with this work we are trying to figure out which Mitogen-Activated Protein Kinase (MAPK) is affected and how it is affected. Methods: Experiments were conducted in May, 2017 at the first affiliated hospital of the Chinese PLA General Hospital, Beijing, China...
January 2018: Pakistan Journal of Medical Sciences Quarterly
Uzma Raza, Mahay Rookh Asif, Asif Bin Rehman, Aminuddin Sheikh
Objective: The study was designed to determine the hyperlipidemia in breast cancer of patients at disease presentation, without any treatment and to correlate these variations with disease stage. Methods: This cross sectional study was conducted at Liaquat National teaching hospital in Karachi from 2006 to 2011, Age and family history of 208 breast cancer patients with infiltrating Ductal Carcinoma were compared with 176 matched control subjects. Married females were selected, with children and short breast feeding period...
January 2018: Pakistan Journal of Medical Sciences Quarterly
Khalida Iqbal, Najmul Islam, Iqbal Azam, Naseema Mehboobali, Mohammad Perwaiz Iqbal
Objective: To investigate the relationship of statins (drug given to reduce serum levels of LDL-cholesterol) on vitamin D levels of Pakistani type 2 diabetes mellitus (DM) patients in a hospital in Karachi. Methods: In a cross-sectional survey, 312 consecutive patients with type 2 DM (219 males and 93 females, age 22-70 years) were recruited with informed consent. A questionnaire was administered to find out whether they were statin users or non-users. Serum was analyzed for concentrations of 25(OH) vitamin D [25(OH)D] and other related biomarkers such as serum cholesterol, triglycerides, HDL-cholesterol, LDL-cholesterol, phosphate and calcium using kit methods...
January 2018: Pakistan Journal of Medical Sciences Quarterly
Murat Calbiyik
Objective: To present our experience on intramedullary nailing device Sonoma Wrx (Sonoma Orthopedic Products Inc., Santa Rosa, CA, USA) used for internal fixation of extra-articular or simple intra-articular distal radius fractures in adult population. Methods: This study was conducted from February 2011 to October 2016. A total of 48 patients (mean age 47.3±5.6 years, 35.4% females) with distal radius fracture, who underwent intramedullary distal radius fixation by using Sonoma Wrx were included in this retrospective study...
January 2018: Pakistan Journal of Medical Sciences Quarterly
Imran Altaf, Shahzad Shams, Anjum Habib Vohra
Objective: Chronic subdural hematoma is one of the most common clinical entities encountered in daily neurosurgical practice. Considerable recurrence rates have been reported for chronic subdural hematoma following surgical evacuation. Many studies have suggested various radiological factors that may be associated with the recurrence of CSDH. However, the results are inconsistent. This study focuses on determining the radiological factors predictive of chronic subdural hematoma recurrence...
January 2018: Pakistan Journal of Medical Sciences Quarterly
Yuqing He, Liping Wei, Wenbo Li
Objective: To analyze and compare the values of computed tomography (CT) and magnetic resonance imaging (MRI) in the diagnosis of early lacunar infarction. Methods: Eighty-eight patients with early lacunar infarction who were admitted to the hospital were selected as research subjects, and all of them underwent MRI and CT. The study was conducted at our hospital between May 2015 to July 2016. Results: Four hundred and forty-one lesions were detected by MRI, and 145 were detected by CT...
January 2018: Pakistan Journal of Medical Sciences Quarterly
Arsalan Manzoor Mughal, Sirajul Haque Shaikh
Objective: Collaborative Problem Solving Empirical Progressions from the Assessment and Teaching of 21st Century Skills (ATC21S) framework were used to determine the level of collaborative problem solving skills (CPS) in first, second and third year MBBS students at Ziauddin College of Medicine during Problem-Based Learning (PBL) sessions. Variations based on gender and roles were studied. Methods: It is an analytical comparative cross-sectional study in which seven PBL groups were selected per year by non-probability convenient sampling...
January 2018: Pakistan Journal of Medical Sciences Quarterly
Pimkhwan Bunjitpimol, Ramesh Kumar, Ratana Somrongthong
Objectives: To evaluate the effect of case based cultural competency level and its factors affecting on nurse job in two private hospitals of Bangkok, Thailand. Methods: This was a quasi-experimental study implemented the cased-based cultural competent intervention in two private hospitals of Thailand in 2015. One hundred sixty six nurses from two control and intervention private hospitals through simple random selection method were selected for this study. Data was collected at the beginning of study (pre-test), immediately after the intervention and after two months of intervention (post-test)...
January 2018: Pakistan Journal of Medical Sciences Quarterly
Noureen Shaukat, Farhat Jaleel, Masood Jawaid, Imrana Zulfiqar
Background & Objective: Chronic pain occurs in 20-30% of patients after hernia surgery. As a consequence of this chronic pain, almost one third of patients have limitations in daily activities. Frequency and severity of this pain varies with different techniques of hernia repair. The objective of this study was to compare polypropylene suture and skin staples for securing mesh in uncomplicated ventral hernioplasty in terms of acute and chronic postoperative pain and to compare the time taken for mesh fixation between polypropylene sutures and skin stapler in ventral hernioplasty...
January 2018: Pakistan Journal of Medical Sciences Quarterly
Cuma Mertoglu, Aliseydi Bozkurt, Ercüment Keskin, Murat Gunay
Objective: To investigate the effect of retrograde intra-renal surgery (RIRS) on kidneys using the myo-inositol oxygenase (MIOX) enzyme. MIOX is a renal tubular-specific novel marker for the early diagnosis of acute kidney injury. Methods: A total of twenty seven individuals that had undergone RIRS to treat kidney stones were included in the study. Biochemical tests were performed on serum samples collected immediately before RIRS (hour 0) and at the 6th and 24th hours after the surgery...
January 2018: Pakistan Journal of Medical Sciences Quarterly
Madiha Sajjad, Rehan Ahmed Khan, Rahila Yasmeen
Objective: To develop a tool to evaluate faculty perceptions of assessment quality in an undergraduate medical program. Methods: The Assessment Implementation Measure (AIM) tool was developed by a mixed method approach. A preliminary questionnaire developed through literature review was submitted to a panel of 10 medical education experts for a three-round 'Modified Delphi technique'. Panel agreement of > 75% was considered the criterion for inclusion of items in the questionnaire...
January 2018: Pakistan Journal of Medical Sciences Quarterly
Supin Liu, Wenlong Wang, Linlin Yin, Yitang Zhu
Objective: To investigate the relationship between serum level of Apelin-13 and bone mineral density (BMD) as well as other parameters, and determine the influence of Apelin-13 on osteoporosis in patients with Type-2 diabetes mellitus. Methods: Seventy-six patients with Type-2 diabetes mellitus were recruited from Department of Endocrinology of our hospital between January 2013 and July2017. The clinical data, including age, gender, height, weight, body mass index (BMI) and disease duration were recorded for all patients...
January 2018: Pakistan Journal of Medical Sciences Quarterly
Asma Chaudhry, Kaleem Ullah Toori, Javaria Ilyas Shaikh
Objective: To identify correlation between biochemical parameters of nutritional status with disease severity in HCV related liver cirrhosis in patients attending tertiary care hospital. Methods: Total 259 HCV related liver cirrhosis patients who attended the outpatient department of KRL Hospital, Islamabad from June 2016 to January 2018 were included in this cross-sectional study. HCV status was confirmed with PCR. Cirrhosis was pre-established by ultrasound, while cirrhosis severity was gauged by CTP score...
January 2018: Pakistan Journal of Medical Sciences Quarterly
Selda Karaveli Cakir, Turkan Ozbayir
Objective: The objective of the study was to determine the effect of preoperative stoma site marking on the health- related quality of life (HRQOL). Methods: A nonrandomized, quasi-experimental design was used for the study performed from June 2013 to August 2014. The study sample (n:60) included patients for whom a stoma was opened after a planned colorectal surgery. The City of Hope Quality of Life-Ostomy Questionnaire (COHQOL-OQ) was used to measure HRQOL. Results: The mean age of the participants in the experimental group was 53...
January 2018: Pakistan Journal of Medical Sciences Quarterly
Riffat Farooqui, Talea Hoor, Nasim Karim, Mehtab Muneer
Objective: To identify and evaluate the frequency, severity, mechanism and common pairs of drug-drug interactions (DDIs) in prescriptions by consultants in medicine outpatient department. Methods: This cross sectional descriptive study was done by Pharmacology department of Bahria University Medical & Dental College (BUMDC) in medicine outpatient department (OPD) of a private hospital in Karachi from December 2015 to January 2016. A total of 220 prescriptions written by consultants were collected...
January 2018: Pakistan Journal of Medical Sciences Quarterly
Aneela Rasul, Amir Rashid, Palvasha Waheed, Saleem Ahmed Khan
Objectives: To study expression of glyoxalase I in patients of diabetic retinopathy. Methods: This cross-sectional comparative study was conducted at Centre for Research in Experimental and Applied Medicine (CREAM), Department of Biochemistry and Molecular Biology, Army Medical College, Rawalpindi in collaboration with Armed Forces Institute of Ophthalmology (AFIO) from January 2015 to November 2015. Sampling technique was non- probability purposive sampling. Total 60 subjects were enrolled in two groups...
January 2018: Pakistan Journal of Medical Sciences Quarterly
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