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https://www.readbyqxmd.com/read/27917361/il28b-genotype-is-associated-with-cirrhosis-or-transition-to-cirrhosis-in-treatment-naive-patients-with-chronic-hcv-genotype-1-infection-the-international-observational-gen-c-study
#1
Alessandra Mangia, Victor De Ledinghen, François Bailly, Javier Brahm, Jazeps Keiss, Jonas Valantinas, Nele Rasmann, Diethelm Messinger, Fernando Tatsch, Georgios Bakalos, Graham R Foster
BACKGROUND AND PURPOSE: Contradictory data exist on the association between host interleukin-28B (IL28B) rs12979860 genotype and liver fibrosis in patients with chronic hepatitis C (CHC). This large, international, observational study (NCT01675427/MV25600) investigated relationships between IL28B rs12979860 genotype and liver fibrosis stage in CHC patients. METHODS: A total of 3003 adult, treatment-naive CHC patients were enrolled into the study. Patients made one study visit to provide a blood sample for genotyping; other data were obtained from medical records...
2016: SpringerPlus
https://www.readbyqxmd.com/read/27917360/load-balancing-prediction-method-of-cloud-storage-based-on-analytic-hierarchy-process-and-hybrid-hierarchical-genetic-algorithm
#2
Xiuze Zhou, Fan Lin, Lvqing Yang, Jing Nie, Qian Tan, Wenhua Zeng, Nian Zhang
With the continuous expansion of the cloud computing platform scale and rapid growth of users and applications, how to efficiently use system resources to improve the overall performance of cloud computing has become a crucial issue. To address this issue, this paper proposes a method that uses an analytic hierarchy process group decision (AHPGD) to evaluate the load state of server nodes. Training was carried out by using a hybrid hierarchical genetic algorithm (HHGA) for optimizing a radial basis function neural network (RBFNN)...
2016: SpringerPlus
https://www.readbyqxmd.com/read/27917359/protective-roles-of-intra-arterial-mild-hypothermia-and-arterial-thrombolysis-in-acute-cerebral-infarction
#3
Xiaoxiang Peng, Yue Wan, Wenjun Liu, Bitang Dan, Li Lin, Zhouping Tang
OBJECTIVE: Herein, we evaluated the efficacy and safety of intra-arterial mild hypothermia in combination with arterial thrombolysis to treat acute cerebral infarction due to middle cerebral artery occlusion. METHODS: A total of 26 patients with acute middle cerebral artery occlusion were divided into a normothermia group (n = 15) and a mild hypothermia group (n = 11). The infarct volumes at 24 h and 7 days after the operation were compared between the normothermia group and the mild hypothermia group...
2016: SpringerPlus
https://www.readbyqxmd.com/read/27917358/rigorous-solution-for-1-d-consolidation-of-a-clay-layer-under-haversine-cyclic-loading-with-rest-period
#4
Nina Müthing, Sabah S Razouki, Maria Datcheva, Tom Schanz
Presented in this paper is a rigorous solution of the conventional Terzaghi one-dimensional consolidation under haversine cyclic loading with any rest period. The clay deposit is either permeable at both top and bottom or permeable at the top and impermeable at the bottom. This exact analytical solution was achieved using Fourier harmonic analysis for the periodic function representing the rate of imposition of excess pore water pressure. The double Fourier series in the rigorous solution was found to be rapidly convergent...
2016: SpringerPlus
https://www.readbyqxmd.com/read/27917357/enhancing-rock-phosphate-integration-rate-for-fast-bio-transformation-of-cow-dung-waste-paper-mixtures-to-organic-fertilizer
#5
F O Unuofin, M Siswana, E N Cishe
Rock phosphate (RP) addition in cow-dung waste-paper mixtures at rates above 2% P has been reported to increase the rate of bio-transformation and humification of organic waste mixtures during vermicomposting to produce organic fertilizer for organic farming. However, the optimization of RP for vermicomposting was not established. The objective of this study was to determine the optimal amount of RP integration rates for effective bio-transformation of cow-dung waste-paper mixtures. Arrays of RP integration degrees (0, 0...
2016: SpringerPlus
https://www.readbyqxmd.com/read/27917356/response-and-recovery-measures-for-two-floods-in-north-china-during-the-nineteenth-century-a-comparative-study
#6
Yu Ye, Xiuqi Fang, Fan Li
BACKGROUND: The process of human response to natural disasters and its mechanisms as revealed by historical events still has a broad significance for modern society. This study analyzed the disaster relief process and the social response for two floods in China: the Yongding River flood in 1801 and the Yellow River flood in 1841. These two floods reflect the different response processes between the national and provincial capitals during a stage of climate cooling and social transition in the Qing dynasty...
2016: SpringerPlus
https://www.readbyqxmd.com/read/27917355/effect-of-climate-change-on-stormwater-runoff-characteristics-and-treatment-efficiencies-of-stormwater-retention-ponds-a-case-study-from-denmark-using-tss-and-cu-as-indicator-pollutants
#7
Anitha Kumari Sharma, Luca Vezzaro, Heidi Birch, Karsten Arnbjerg-Nielsen, Peter Steen Mikkelsen
This study investigated the potential effect of climate changes on stormwater pollution runoff characteristics and the treatment efficiency of a stormwater retention pond in a 95 ha catchment in Denmark. An integrated dynamic stormwater runoff quality and treatment model was used to simulate two scenarios: one representing the current climate and another representing a future climate scenario with increased intensity of extreme rainfall events and longer dry weather periods. 100-year long high-resolution rainfall time series downscaled from regional climate model projections were used as input...
2016: SpringerPlus
https://www.readbyqxmd.com/read/27917354/results-of-a-hydroxyapatite-coated-femoral-stem-corail-in-chinese-a-minimum-10-year-follow-up
#8
Jianda Xu, Zikang Xie, Jianning Zhao, Yi Gao, Hong Zhao, Libo Peng, Yuxing Qu
BACKGROUND: Due to the adverse effects of cemented hip arthroplasty, uncemented stems with hydroxyapatite (HA) coating reduces these risks and enhanced integration. The concept of an extensive HA coating for the fixation of a tapered femoral stem (Corail(®)) was introduced, which can achieve durable biological fixation and preserve normal periprosthetic bone activity. Here we describe the clinical and radiological outcome in patients with the Corail(®) stem. METHODS: 92 total hip replacements in 81 patients using the Corail(®) stem were followed-up...
2016: SpringerPlus
https://www.readbyqxmd.com/read/27917353/application-of-the-mike21c-model-to-simulate-flow-in-the-lower-mekong-river-basin
#9
Truong An Dang, Tuan Hoang Tran
Numerical models are useful tools that play an important role in many research projects. Mike21C is one of the most well-established models for simulating a variety of processes, including bank erosion, bed level variations, aggradation, and degradation. Such processes are caused by a variety of activities, such as construction and dredging, as well as seasonal flow fluctuations. Mike21C based on an orthogonal curvilinear grid, which enables a computational speed that is faster than that of other grids. The hydrodynamic part of the model is based on solving the Saint-Venant equations...
2016: SpringerPlus
https://www.readbyqxmd.com/read/27917352/interval-valued-fuzzy-formula-see-text-tolerance-competition-graphs
#10
Tarasankar Pramanik, Sovan Samanta, Madhumangal Pal, Sukumar Mondal, Biswajit Sarkar
This paper develops an interval-valued fuzzy [Formula: see text]-tolerance competition graphs which is the extension of basic fuzzy graphs and [Formula: see text] is any real valued function. Interval-valued fuzzy [Formula: see text]-tolerance competition graph is constructed by taking all the fuzzy sets of a fuzzy [Formula: see text]-tolerance competition graph as interval-valued fuzzy sets. Product of two IVFPTCGs and relations between them are defined. Here, some hereditary properties of products of interval-valued fuzzy [Formula: see text]-tolerance competition graphs are represented...
2016: SpringerPlus
https://www.readbyqxmd.com/read/27917351/the-distribution-of-some-extremum-on-the-risk-process-whose-income-depend-on-the-current-reserve
#11
Jingmin He, Zaiming Liu, Wei Zhang
This paper considers the distribution of some extremum on the risk process whose income depend on the current reserve. We first construct the defective renewal sequence and obtain the density function of them. By the presented renewal measure and the strong Markov property, the distribution of the first hitting time is obtained explicitly. Then, the ruin probability and the probability that the surplus process less than x is obtained. Furthermore, the distribution of supreme profits before ruin, the joint distributions of the supreme profit and the deficit before the time of the surplus process first up-crossing level zero after ruin, and the joint distributions of the supreme profit and the deficit before the surplus process leave zero ultimately are derived...
2016: SpringerPlus
https://www.readbyqxmd.com/read/27917350/completeness-and-regularity-of-generalized-fuzzy-graphs
#12
Sovan Samanta, Biswajit Sarkar, Dongmin Shin, Madhumangal Pal
Fuzzy graphs are the backbone of many real systems like networks, image, scheduling, etc. But, due to some restriction on edges, fuzzy graphs are limited to represent for some systems. Generalized fuzzy graphs are appropriate to avoid such restrictions. In this study generalized fuzzy graphs are introduced. In this study, matrix representation of generalized fuzzy graphs is described. Completeness and regularity are two important parameters of graph theory. Here, regular and complete generalized fuzzy graphs are introduced...
2016: SpringerPlus
https://www.readbyqxmd.com/read/27917349/effect-of-acute-salinity-stress-on-ion-homeostasis-na-k-atpase-and-histological-structure-in-sea-cucumber-apostichopus-japonicus
#13
Chenfan Geng, Yi Tian, Yanpeng Shang, Liqiang Wang, Yanan Jiang, Yaqing Chang
BACKGROUND: Sea cucumbers (Apostichopus japonicus) are an imperiled fauna exposed to a variety of environmental condition such as salinity and studies are urgently needed to assess their effects to guide aquaculture efforts. The effects of acute salinity stress on coelomic fluid osmotic pressure, ion concentrations, the activity of Na(+)/K(+)-ATPase in respiratory trees and the histological variations were measured to evaluate the salinity tolerance of sea cucumbers. RESULTS: Significant correlations in osmotic pressure were observed between coelomic fluid and ambient environmental salinity...
2016: SpringerPlus
https://www.readbyqxmd.com/read/27917348/resolution-of-constipation-anal-stricture-and-iron-deficiency-anemia-after-iron-infusion-an-analogy-with-plummer-vinson-syndrome
#14
Vijaypal Arya, Shikha Singh, Shashank Agarwal, Arjun Ohri
BACKGROUND: Anal stricture is a disabling condition which is often unresponsive to conservative medical management. The complications of surgical procedures such as dilatations and anoplasty make it a formidable treatment challenge. Through this case, we report and explore a new medical treatment for ano-rectal strictures with an analogy to Plummer Vinson syndrome. A 69-year-old male presented with chronic constipation, rectal pain, and easy fatigability. The physical exam was negative for anal fissure and a digital rectal examination could not be completed because an index finger could not be advanced through the narrowed anus...
2016: SpringerPlus
https://www.readbyqxmd.com/read/27917347/identification-of-lumbar-disc-disease-hallmarks-a-large-cross-sectional-study
#15
Jun Zhang, Fei Zhao, Feng-Liang Wang, Yong-Feng Yang, Chen Zhang, Yue Cao, You-Lin Wang, Xiao-Juan Shi, Yi Wan, Min Zhang, Meng-Qiao Liu, Chun-Guang Zuo, Hai-Qiang Wang
BACKGROUND: Lumbar disc disease has a disabling impact on global people with heavy burden on society, mainly consisting of lumbar disc degeneration (LDD) and lumbar disc herniation (LDH). The recently released lumbar disc nomenclature version 2.0 deepens our understandings on the diseases. Consequently, there is an urgent need to clarify the occurrence and distribution features of LDD and LDH in a large-scale sample in terms of the novel version. QUESTION/PURPOSES: We asked: (1) Is there a difference in the occurrence and distribution hallmarks of LDD and LDH in a population-based large-scale sample? (2) Does the novel nomenclature version bring novel vision on lumbar disc disease? METHODS: Five thousand two hundred eighty-eight consecutive cases (26,440 lumbar discs) undergoing lumbar spine MRI were retrospectively included from Jan 2008 to Dec 2010 in a territory university hospital...
2016: SpringerPlus
https://www.readbyqxmd.com/read/27917346/neonatal-bacterial-meningitis-in-tikur-anbessa-specialized-hospital-ethiopia-a-10-year-retrospective-review
#16
Melese Abate Reta, Tamrat Abebe Zeleke
BACKGROUND: Bacterial meningitis is still a major public health threat in developing countries. It is an overwhelming infection with a high morbidity and mortality rate, especially in neonates. The aim of this study was to determine the prevalence and etiological agents that cause bacterial neonatal meningitis at Tikur Anbessa Specialized Hospital (TASH). METHODS: This is a retrospective analysis of 1189 cerebrospinal fluid (CSF) specimens submitted to the bacteriology laboratory of TASH for culture from 2001 to 2010...
2016: SpringerPlus
https://www.readbyqxmd.com/read/27917345/cholecystectomy-and-duodenogastric-reflux-interacting-effects-over-the-gastric-mucosa
#17
Erdinc Mercan, Ugur Duman, Deniz Tihan, Evren Dilektasli, Kazim Senol
AIMS: To evaluate association between duodenogastric reflux and early gastric mucosal changes before and after the cholecystectomy procedure. MATERIALS AND METHODS: Patients were evaluated with preoperative and postoperative endoscopy and endoscopic biopsy. Demographic and clinical characteristics, histological parameters, presence of duodenogastric reflux, and Updated Sydney scores were noted. RESULTS: A total of fifty patients who obeyed the follow-up were enrolled into the study...
2016: SpringerPlus
https://www.readbyqxmd.com/read/27917344/research-on-early-warning-index-of-the-spatial-temperature-field-in-concrete-dams
#18
Guang Yang, Chongshi Gu, Tengfei Bao, Zhenming Cui, Kan Kan
Warning indicators of the dam body's temperature are required for the real-time monitoring of the service conditions of concrete dams to ensure safety and normal operations. Warnings theories are traditionally targeted at a single point which have limitations, and the scientific warning theories on global behavior of the temperature field are non-existent. In this paper, first, in 3D space, the behavior of temperature field has regional dissimilarity. Through the Ward spatial clustering method, the temperature field was divided into regions...
2016: SpringerPlus
https://www.readbyqxmd.com/read/27917343/a-new-bioinformatic-insight-into-the-associated-proteins-in-psychiatric-disorders
#19
Wenlong Zhao, Wenjing Yang, Shuanglin Zheng, Qiong Hu, Ping Qiu, Xinghua Huang, Xiaoqian Hong, Fenghua Lan
BACKGROUND: Psychiatric diseases severely affect the quality of patients' lives and bring huge economic pressure to their families. Also, the great phenotypic variability among these patients makes it difficult to investigate the pathogenesis. Nowadays, bioinformatics is hopeful to be used as an effective tool for the diagnosis of psychiatric disorders, which can identify sensitive biomarkers and explore associated signaling pathways. METHODS: In this study, we performed an integrated bioinformatic analysis on 1945 mental-associated proteins including 91 secreted proteins and 593 membrane proteins, which were screened from the Universal Protein Resource (Uniport) database...
2016: SpringerPlus
https://www.readbyqxmd.com/read/27917342/genomic-studies-of-envelope-gene-sequences-from-mosquito-and-human-samples-from-bangkok-thailand
#20
Pannamthip Pitaksajjakul, Surachet Benjathummarak, Hyun Ngoc Son, Supatra Thongrungkiat, Pongrama Ramasoota
Dengue virus (DENV) is an RNA virus showing a high degree of genetic variation as a consequence of its proofreading inability. This variation plays an important role in virus evolution and pathogenesis. Although levels of within-host genetic variation are similar following equilibrium, variation among different hosts is frequently different. To identify dengue quasispecies present among two hosts, we collected patient samples from six acute DENV cases and two pools of Aedes aegypti mosquitoes and analyzed the genetic variation of regions of the viral envelope gene...
2016: SpringerPlus
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