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Case Reports in Transplantation

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https://www.readbyqxmd.com/read/30002942/inadvertent-traumatic-fracture-of-central-venous-catheter-during-procurement-transmitted-through-solid-organ-transplant
#1
Thaer Obaid, Corinne Cricco, Ani Simka, Richard Fine, Saravanan Ramamoorthy, Radi Zaki
Central venous catheters play a pivotal role in the perioperative support of critically ill patients. They are used for administration of fluids, vasopressors, blood products, and various medications; however, their use may be associated with serious complications, such as catheter fracture and embolization. While most data on catheter fracture embolization consist of isolated case reports, only a few studies have examined patients with central venous catheter embolism. We report a traumatic inadvertent transection of central venous catheter that migrated through a donor transplanted liver and was found to be lodged in the recipient's right ventricle...
2018: Case Reports in Transplantation
https://www.readbyqxmd.com/read/29977640/nerve-surgery-to-treat-intractable-genitofemoral-neuropathic-pain-following-laparoscopic-live-kidney-donation
#2
K Ramdhani, M J A Malessy, M J G Simon, V A L Huurman
To date live laparoscopic donor nephrectomies (LLDN) are frequently performed. The most common complications entail bleeding, wound infection, and incisional hernia. Here we discuss a 50-year-old patient with a severe less known complication, namely, postoperative persistent neuropathic pain in the scrotum and left upper leg. Satisfactory pain control could not be obtained in 3 years of postoperative pain treatment which consisted of neuroleptic drugs, blocks of the L1/L2 dorsal roots with local anaesthetics, and pulsed radiofrequency lesioning...
2018: Case Reports in Transplantation
https://www.readbyqxmd.com/read/29955411/de-novo-postinfectious-glomerulonephritis-secondary-to-nephritogenic-streptococci-as-the-cause-of-transplant-acute-kidney-injury-a-case-report-and-review-of-the-literature
#3
Alexander Bullen, Mita M Shah
Acute kidney injury is common among kidney transplant recipients. Postinfectious glomerulonephritis secondary to nephritogenic streptococci is one of the oldest known etiologies of acute kidney injury in native kidneys but rarely reported among kidney transplant recipients. This report is of a biopsy-proven case of acute kidney injury in a renal allograft recipient caused by de novo poststreptococcal glomerulonephritis.
2018: Case Reports in Transplantation
https://www.readbyqxmd.com/read/29888023/absence-of-rejection-in-a-facial-allograft-recipient-with-a-positive-flow-crossmatch-24-months-after-induction-with-rabbit-anti-thymocyte-globulin-and-anti-cd20-monoclonal-antibody
#4
Bruce E Gelb, J Rodrigo Diaz-Siso, Natalie M Plana, Adam Jacoby, William J Rifkin, Kimberly S Khouri, Daniel J Ceradini, Eduardo D Rodriguez
Background: Donor-specific antibodies (DSA) to human leukocyte antigen increase the risk of accelerated rejection and allograft damage and reduce the likelihood of successful transplantation. Patients with full-thickness facial burns may benefit from facial allotransplantation. However, they are at a high risk of developing DSA due to standard features of their acute care. Case Presentation: A 41-year-old male with severe disfigurement from facial burns consented to facial allotransplantation in 2014; panel reactive antibody score was 0%...
2018: Case Reports in Transplantation
https://www.readbyqxmd.com/read/29854547/neutropenic-enterocolitis-in-a-pediatric-heart-transplant-recipient-on-multiple-immunosuppressants
#5
Emily E Miller, Leigh Christopher Reardon
Neutropenic enterocolitis (NE) historically primarily affects pediatric patients with leukemia who are undergoing chemotherapy or who have recently received bone marrow transplants. Although a few case reports have shown NE occurring outside of this typical population, to our knowledge, this is the first published case of NE occurring in the setting of pediatric heart transplant. This patient was diagnosed several months after pediatric heart transplant, with radiographs showing evidence of pneumatosis intestinalis...
2018: Case Reports in Transplantation
https://www.readbyqxmd.com/read/29850365/combination-of-modified-bentall-procedure-and-orthotopic-liver-transplantation
#6
Philipp C Seppelt, Rebecca von Haken, Jens Werner, Klaus Kallenbach
Indication for combined cardiac surgery and orthotopic liver transplantation is rare and patients are at high risks. Individual surgical strategy must be developed since a general standard of such procedure does not exist. We report the case of a 45-year-old woman who underwent simultaneously modified Bentall procedure and orthotopic liver transplantation. Underlying diseases were end-stage polycystic liver, aneurysm of the ascending aorta, and severe aortic regurgitation. To avoid prolonged bypass times, both teams worked simultaneously...
2018: Case Reports in Transplantation
https://www.readbyqxmd.com/read/29850364/hepatic-epithelioid-hemangioendothelioma-presenting-as-an-enlarging-vascular-lesion-within-the-spleen
#7
Juliet A Emamaullee, Klaudia Nowak, Marla Beach, Julinor Bacani, A M James Shapiro
Epithelioid hemangioendothelioma (EHE) is a rare vascular neoplasm with variable malignant potential that most often presents within the liver. Many patients present with bilobar or extrahepatic disease, and the current treatment paradigm involves liver transplantation, with favorable long term results. Up to 25% of patients are diagnosed incidentally following imaging for other indications, and confirmation of diagnosis requires histologic analysis, as there are no classical imaging features to distinguish hepatic EHE (HEHE) from other solid hepatic lesions...
2018: Case Reports in Transplantation
https://www.readbyqxmd.com/read/29725551/domino-liver-transplantation-from-a-child-with-propionic-acidemia-to-a-child-with-idiopathic-fulminant-hepatic-failure
#8
Marina Moguilevitch, Ellise Delphin
Domino liver transplant has emerged as a viable strategy to increase the number of grafts available for transplantation. In the domino transplant organs explanted from one patient are transplanted into another patient. The first successful domino liver transplant was performed in Portugal in 1995. Since then this innovative concept has been applied to several genetic or biochemical disorders that are treated by liver transplantation. An important consideration during this operation is that such livers can pose a risk of the de novo development of the disease in the recipient...
2018: Case Reports in Transplantation
https://www.readbyqxmd.com/read/29721346/hsct-gave-as-a-manifestation-of-chronic-graft-versus-host-disease-a-case-report-and-review-of-the-existing-literature
#9
Michael J Grant, Mitchell E Horwitz
Gastric antral vascular ectasia or "watermelon stomach" is a significant cause of nonvariceal upper GI bleeding and is characterized by red, tortuous ectatic vessels along longitudinal folds in the gastric antrum. The existing literature links GAVE to patients with cirrhosis, scleroderma, bone marrow transplantation, and chronic renal failure among other associations, but its pathophysiology remains ill-defined. Over 30 cases of hematopoietic stem cell transplant-related GAVE (HSCT-GAVE) have been reported in the literature to date and there are likely many more that go undiagnosed or are attributed to another cause of upper gastrointestinal bleeding...
2018: Case Reports in Transplantation
https://www.readbyqxmd.com/read/29568659/primary-nocardia-infection-causing-a-fluorodeoxyglucose-avid-right-renal-mass-in-a-redo-lung-transplant-recipient
#10
Sreeja Biswas Roy, Mitchell D Ross, Pradnya D Patil, Richard Trepeta, Ross M Bremner, Tanmay S Panchabhai
Immunosuppression after lung transplantation may increase susceptibility to opportunistic infection and is associated with early and delayed deaths in lung transplant recipients. Factors that may predispose lung transplant recipients to opportunistic bacterial and fungal infections include prolonged corticosteroid use, renal impairment, treatment of acute rejection, and post-transplant diabetes mellitus. We present a unique case of a 63-year-old woman with diabetes mellitus who underwent redo lung transplantation...
2018: Case Reports in Transplantation
https://www.readbyqxmd.com/read/29487756/liver-transplant-for-unusually-large-polycystic-liver-disease-challenges-and-pitfalls
#11
Pablo Serrano Rodriguez, Alfred Sidney Barritt, David Allen Gerber, Chirag Sureshchandra Desai
Patients with polycystic liver disease are described in the literature as both recipient and donor for liver transplant. Due to well-preserved liver function, it is often difficult for these patients to receive an organ. Livers of these patients are often large and heavier than a normal organ. We describe two cases who had exceedingly large livers, weighing 14 and 19 kg. To the best of our knowledge and search, these are some of the heaviest explanted livers, and one of the patients incidentally received a liver from a donor with ADPKD...
2018: Case Reports in Transplantation
https://www.readbyqxmd.com/read/29445563/eculizumab-for-thrombotic-microangiopathy-associated-with-antibody-mediated-rejection-after-abo-incompatible-kidney-transplantation
#12
Luca Lanfranco, Melanie Joly, Arnaud Del Bello, Laure Esposito, Noelle Cognard, Peggy Perrin, Bruno Moulin, Nassim Kamar, Sophie Caillard
Thrombotic microangiopathy is a form of antibody-mediated rejection (ABMR): it is the main complication of ABO-incompatible (ABOi) kidney transplantation (KT). Herein, we report on two cases of ABMR with biological and histological features of thrombotic microangiopathy (TMA) that were treated by eculizumab after ABOi KT. The first patient presented with features of TMA at postoperative day (POD) 13. Because of worsening biological parameters and no recovery of kidney function, despite seven sessions of immunoadsorption, a salvage therapy of eculizumab was started on POD 23...
2017: Case Reports in Transplantation
https://www.readbyqxmd.com/read/29391965/unusual-case-of-severe-lactic-acidosis-in-a-liver-transplant-patient
#13
Shweta Yemul Golhar, Michael S Green, Stephen Guy
Lactic acidosis is a standard indicator for oxygen debt and some other very significant causes. We describe a case of liver transplant patient presenting with vague abdominal pain and lactic acidosis without any liver dysfunction/failure/ischemia/rejection or sepsis. The imaging studies showed vague bowel edema and normal hepatic perfusion. The patient continued to deteriorate with rising lactic acidosis when a repeat CT abdomen eventually showed signs of lymphomatosis peritonei. Biopsy revealed the unusual diagnosis of posttransplant lymphoproliferative disorder...
2017: Case Reports in Transplantation
https://www.readbyqxmd.com/read/29348962/primary-cytomegalovirus-infection-causing-guillain-barr%C3%A3-syndrome-in-a-living-renal-allograft-recipient
#14
Massini Merzkani, Ezra Israel, Mala Sachdeva
Guillain-Barré Syndrome (GBS) is a common acute autoimmune polyneuropathy in adults. There have been few reported cases of Guillain-Barré Syndrome associated with active cytomegalovirus (CMV) infection in renal transplant recipients. Here we present a case of active CMV viremia inducing Guillain-Barré Syndrome in a renal transplant recipient. We discuss the treatment regimen utilized. Furthermore, we performed a review of the literature and discuss the cases of CMV induced GBS in renal transplant recipients...
2017: Case Reports in Transplantation
https://www.readbyqxmd.com/read/29230343/unusual-pathology-in-a-kidney-from-a-heart-transplant-patient
#15
Marie Larcher, Audey Delas, Clément Delmas, Olivier Cointault, Camille Dambrin, Arnaud Del Bello, Nassim Kamar
Acute kidney injury (AKI) is often observed after heart transplantation. In this setting, acute tubular necrosis is the main histological finding on kidneys. We report the unusual pathology found in a kidney from a heart-transplant patient. The patient experienced several hemodynamic insults, massive transfusion, and implantation of a mechanical circulatory-support device before heart transplantation: there was prolonged AKI after transplantation. A kidney biopsy revealed acute tubular necrosis and renal hemosiderosis, which was probably related to the transfusion and to mechanical circulatory-support device-induced intravascular hemolysis...
2017: Case Reports in Transplantation
https://www.readbyqxmd.com/read/29201486/gallstone-pancreatitis-a-common-but-often-overlooked-cause-of-abdominal-pain-in-post-liver-transplant-patients
#16
Napatt Kanjanahattakij, Kamolyut Lapumnuaypol, Sanna Fatima, Eyob Feyssa
Introduction: In general population, gallstone pancreatitis is the most common cause of pancreatitis. However, there are very few literatures that address this topic in post-liver-transplant patients. Clinical Case: A 69-year-old female who had a liver transplant in 2015 due to hepatocellular carcinoma and nonalcoholic steatohepatitis (NASH) cirrhosis. She had a recent episode of acute cellular rejection that was treated with high dose methylprednisolone 1 week prior to admission...
2017: Case Reports in Transplantation
https://www.readbyqxmd.com/read/29158940/posttransplant-lymphoproliferative-disease-presenting-as-an-extracranial-mass
#17
Reuben J Arasaratnam, Alejandro Restrepo
Posttransplant lymphoproliferative disease is a serious complication following stem cell and solid organ transplantation. Early recognition of the disease is important in facilitating timely therapy and improving long-term outcomes. We report a renal transplant recipient presenting with an extracranial frontoparietal soft tissue mass that was subsequently diagnosed as a B-cell lymphoma. The patient was treated successfully with immunosuppression reduction, anti-CD20 monoclonal antibody therapy, and cytotoxic chemotherapy...
2017: Case Reports in Transplantation
https://www.readbyqxmd.com/read/29130016/incidental-eosinophilic-chromophobe-renal-cell-carcinoma-in-renal-allograft
#18
Abdullah Alharbi, Maram S Al Turki, Noura Aloudah, Khaled O Alsaad
The incidence of renal cell carcinoma (RCC) in renal allograft in transplant recipients is 0.22-0.25%. De novo clear cell, papillary, and chromophobe RCCs and RCCs with sarcomatoid differentiation originating in renal allograft have been reported. Routine surveillance for graft tumours is not routinely practiced and these tumours are commonly asymptomatic and incidentally discovered. We describe a case of incidental, eosinophilic chromophobe RCC in a 31-year-old, long-term renal transplant male recipient, who presented with acute gastroenteritis 11 years after transplantation...
2017: Case Reports in Transplantation
https://www.readbyqxmd.com/read/29123936/reconstruction-of-a-damaged-lower-polar-artery-for-kidney-transplantation-using-tubularised-donor-aorta
#19
A J Vicéns-Morton, C Callaghan, J Olsburgh
Introduction: Live donors, extended donor criteria, and the maximum usage of organs with anatomical variants are some of the mechanisms used to increase the number of organs available. Case: We present the case of a kidney transplant, in which the organ had an iatrogenic injury to a lower pole arterial branch during retrieval. The donor was a 35-year-old male (DCD, Maastricht III). The right kidney was accepted; it had three veins in a single cava patch and three renal arteries, the main artery with aorta patch that is 8 cm long...
2017: Case Reports in Transplantation
https://www.readbyqxmd.com/read/29085699/unusual-manifestations-of-acute-cytomegalovirus-infection-in-solid-organ-transplant-hosts-a-report-of-two-cases
#20
Alfredo Mena Lora, Justin Khine, Nadia Khosrodad, Vijay Yeldandi
Cytomegalovirus (CMV) infection is a common cause of morbidity and mortality in immunocompromised hosts. Tissue-invasive CMV disease causing ulcerative skin disease or esophageal necrosis is rare. We herein describe two cases: a 47-year-old renal and pancreas transplant recipient who presented with skin ulcerations on his elbow and a 50-year-old renal transplant recipient who presented with acute esophageal necrosis. In both, tissue biopsy revealed CMV inclusion bodies by immunohistochemical staining of infected endothelial and mucosal cells...
2017: Case Reports in Transplantation
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