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JAMA Psychiatry

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https://www.readbyqxmd.com/read/28813562/polygenic-scores-for-major-depressive-disorder-and-risk-of-alcohol-dependence
#1
Allan M Andersen, Robert H Pietrzak, Henry R Kranzler, Li Ma, Hang Zhou, Xiaoming Liu, John Kramer, Samuel Kuperman, Howard J Edenberg, John I Nurnberger, John P Rice, Jay A Tischfield, Alison Goate, Tatiana M Foroud, Jacquelyn L Meyers, Bernice Porjesz, Danielle M Dick, Victor Hesselbrock, Eric Boerwinkle, Steven M Southwick, John H Krystal, Myrna M Weissman, Douglas F Levinson, James B Potash, Joel Gelernter, Shizhong Han
Importance: Major depressive disorder (MDD) and alcohol dependence (AD) are heritable disorders with significant public health burdens, and they are frequently comorbid. Common genetic factors that influence the co-occurrence of MDD and AD have been sought in family, twin, and adoption studies, and results to date have been promising but inconclusive. Objective: To examine whether AD and MDD overlap genetically, using a polygenic score approach. Design, Settings, and Participants: Association analyses were conducted between MDD polygenic risk score (PRS) and AD case-control status in European ancestry samples from 4 independent genome-wide association study (GWAS) data sets: the Collaborative Study on the Genetics of Alcoholism (COGA); the Study of Addiction, Genetics, and Environment (SAGE); the Yale-Penn genetic study of substance dependence; and the National Health and Resilience in Veterans Study (NHRVS)...
August 16, 2017: JAMA Psychiatry
https://www.readbyqxmd.com/read/28813554/association-between-purpose-in-life-and-objective-measures-of-physical-function-in-older-adults
#2
Eric S Kim, Ichiro Kawachi, Ying Chen, Laura D Kubzansky
Importance: Higher purpose in life is hypothesized to reduce the likelihood of developing weak grip strength and slow walking speed because purpose has been linked with a range of positive health behaviors and biological processes that are potentially protective against declining physical function. However, the association between purpose in life and objective physical function has not been examined. Objective: To assess whether higher purpose in life among adequately functioning older adults is associated with lower risk of developing weak grip strength and slow walking speed over time...
August 16, 2017: JAMA Psychiatry
https://www.readbyqxmd.com/read/28813553/the-benefits-of-purposeful-life-engagement-on-later-life-physical-function
#3
Carol D Ryff
No abstract text is available yet for this article.
August 16, 2017: JAMA Psychiatry
https://www.readbyqxmd.com/read/28793148/ineffective-policies-to-address-the-opioid-epidemic-reply
#4
Bertha K Madras
No abstract text is available yet for this article.
August 9, 2017: JAMA Psychiatry
https://www.readbyqxmd.com/read/28793147/comparing-public-safety-outcomes-for-traditional-probation-vs-specialty-mental-health-probation
#5
Jennifer L Skeem, Sarah Manchak, Lina Montoya
Importance: Probation is a cornerstone of efforts to reduce mass incarceration. Although it is understudied, specialty probation could improve outcomes for the overrepresented group of people with mental illness. Objective: To test whether specialty probation yields better public safety outcomes than traditional probation. Design, Setting, and Participants: A longitudinal observational study with group matching on age, sex, race/ethnicity, probation time, and offense at 2 urban agencies that exemplify specialty and traditional probation...
August 9, 2017: JAMA Psychiatry
https://www.readbyqxmd.com/read/28793142/remarkable-increases-in-alcohol-use-disorders
#6
Marc A Schuckit
No abstract text is available yet for this article.
August 9, 2017: JAMA Psychiatry
https://www.readbyqxmd.com/read/28793133/prevalence-of-12-month-alcohol-use-high-risk-drinking-and-dsm-iv-alcohol-use-disorder-in-the-united-states-2001-2002-to-2012-2013-results-from-the-national-epidemiologic-survey-on-alcohol-and-related-conditions
#7
Bridget F Grant, S Patricia Chou, Tulshi D Saha, Roger P Pickering, Bradley T Kerridge, W June Ruan, Boji Huang, Jeesun Jung, Haitao Zhang, Amy Fan, Deborah S Hasin
Importance: Lack of current and comprehensive trend data derived from a uniform, reliable, and valid source on alcohol use, high-risk drinking, and DSM-IV alcohol use disorder (AUD) represents a major gap in public health information. Objective: To present nationally representative data on changes in the prevalences of 12-month alcohol use, 12-month high-risk drinking, 12-month DSM-IV AUD, 12-month DSM-IV AUD among 12-month alcohol users, and 12-month DSM-IV AUD among 12-month high-risk drinkers between 2001-2002 and 2012-2013...
August 9, 2017: JAMA Psychiatry
https://www.readbyqxmd.com/read/28793132/errors-in-results-and-tables
#8
(no author information available yet)
No abstract text is available yet for this article.
August 9, 2017: JAMA Psychiatry
https://www.readbyqxmd.com/read/28793131/ineffective-policies-to-address-the-opioid-epidemic
#9
William B Weeks, Christine M Goertz
No abstract text is available yet for this article.
August 9, 2017: JAMA Psychiatry
https://www.readbyqxmd.com/read/28768336/transdiagnostic-cognitive-behavioral-therapy-and-the-return-of-the-repressed
#10
Peter Roy-Byrne
No abstract text is available yet for this article.
August 2, 2017: JAMA Psychiatry
https://www.readbyqxmd.com/read/28768334/effect-of-internet-based-guided-self-help-vs-individual-face-to-face-treatment-on-full-or-subsyndromal-binge-eating-disorder-in-overweight-or-obese-patients-the-interbed-randomized-clinical-trial
#11
Martina de Zwaan, Stephan Herpertz, Stephan Zipfel, Jennifer Svaldi, Hans-Christoph Friederich, Frauke Schmidt, Andreas Mayr, Tony Lam, Carmen Schade-Brittinger, Anja Hilbert
Importance: Although cognitive behavioral therapy (CBT) represents the criterion standard for treatment of binge eating disorder (BED), most individuals do not have access to this specialized treatment. Objective: To evaluate the efficacy of internet-based guided self-help (GSH-I) compared with traditional, individual face-to-face CBT. Design, Setting, and Participants: The Internet and Binge Eating Disorder (INTERBED) study is a prospective, multicenter, randomized, noninferiority clinical trial (treatment duration, 4 months; follow-ups, 6 months and 1...
August 2, 2017: JAMA Psychiatry
https://www.readbyqxmd.com/read/28768327/the-unified-protocol-for-transdiagnostic-treatment-of-emotional-disorders-compared-with-diagnosis-specific-protocols-for-anxiety-disorders-a-randomized-clinical-trial
#12
David H Barlow, Todd J Farchione, Jacqueline R Bullis, Matthew W Gallagher, Heather Murray-Latin, Shannon Sauer-Zavala, Kate H Bentley, Johanna Thompson-Hollands, Laren R Conklin, James F Boswell, Amantia Ametaj, Jenna R Carl, Hannah T Boettcher, Clair Cassiello-Robbins
Importance: Transdiagnostic interventions have been developed to address barriers to the dissemination of evidence-based psychological treatments, but only a few preliminary studies have compared these approaches with existing evidence-based psychological treatments. Objective: To determine whether the Unified Protocol for Transdiagnostic Treatment of Emotional Disorders (UP) is at least as efficacious as single-disorder protocols (SDPs) in the treatment of anxiety disorders...
August 2, 2017: JAMA Psychiatry
https://www.readbyqxmd.com/read/28768326/the-importance-of-a-valid-comparison-group
#13
Natalie Mota, Jessica Enns, Laurence Y Katz
No abstract text is available yet for this article.
August 2, 2017: JAMA Psychiatry
https://www.readbyqxmd.com/read/28768323/the-importance-of-a-valid-comparison-group-reply
#14
Florian Walter, Carsten B Pedersen, Roger T Webb
No abstract text is available yet for this article.
August 2, 2017: JAMA Psychiatry
https://www.readbyqxmd.com/read/28768322/state-dependent-cross-brain-information-flow-in-borderline-personality-disorder
#15
Edda Bilek, Gabriela Stößel, Axel Schäfer, Laura Clement, Matthias Ruf, Lydia Robnik, Corinne Neukel, Heike Tost, Peter Kirsch, Andreas Meyer-Lindenberg
Importance: Although borderline personality disorder (BPD)-one of the most common, burdensome, and costly psychiatric conditions-is characterized by repeated interpersonal conflict and instable relationships, the neurobiological mechanism of social interactive deficits remains poorly understood. Objective: To apply recent advancements in the investigation of 2-person human social interaction to investigate interaction difficulties among people with BPD. Design, Setting, and Participants: Cross-brain information flow in BPD was examined from May 25, 2012, to December 4, 2015, in pairs of participants studied in 2 linked functional magnetic resonance imaging scanners in a university setting...
August 2, 2017: JAMA Psychiatry
https://www.readbyqxmd.com/read/28768316/interactional-dysfunction-of-the-social-brain-in-a-paradigmatic-relational-disorder-from-one-island-to-another
#16
Michael J Minzenberg
No abstract text is available yet for this article.
August 2, 2017: JAMA Psychiatry
https://www.readbyqxmd.com/read/28768312/association-of-white-matter-with-core-cognitive-deficits-in-patients-with-schizophrenia
#17
Peter Kochunov, Thomas R Coyle, Laura M Rowland, Neda Jahanshad, Paul M Thompson, Sinead Kelly, Xiaoming Du, Hemalatha Sampath, Heather Bruce, Joshua Chiappelli, Meghann Ryan, Feven Fisseha, Anya Savransky, Bhim Adhikari, Shuo Chen, Sara A Paciga, Christopher D Whelan, Zhiyong Xie, Craig L Hyde, Xing Chen, Christian R Schubert, Patricio O'Donnell, L Elliot Hong
Importance: Efforts to remediate the multiple cognitive function impairments in schizophrenia should consider white matter as one of the underlying neural mechanisms. Objective: To determine whether altered structural brain connectivity is responsible for 2 of the core cognitive deficits in schizophrenia- reduced information processing speed and impaired working memory. Design, Setting, and Participants: This cross-sectional study design took place in outpatient clinics from August 1, 2004, to August 31, 2015...
August 2, 2017: JAMA Psychiatry
https://www.readbyqxmd.com/read/28746720/clinical-care-across-cultures-what-helps-what-hinders-what-to-do
#18
Margarita Alegría, Kiara Alvarez, Irene Falgas-Bague
No abstract text is available yet for this article.
July 26, 2017: JAMA Psychiatry
https://www.readbyqxmd.com/read/28746715/identification-of-genetic-loci-jointly-influencing-schizophrenia-risk-and-the-cognitive-traits-of-verbal-numerical-reasoning-reaction-time-and-general-cognitive-function
#19
Olav B Smeland, Oleksandr Frei, Karolina Kauppi, W David Hill, Wen Li, Yunpeng Wang, Florian Krull, Francesco Bettella, Jon A Eriksen, Aree Witoelar, Gail Davies, Chun C Fan, Wesley K Thompson, Max Lam, Todd Lencz, Chi-Hua Chen, Torill Ueland, Erik G Jönsson, Srdjan Djurovic, Ian J Deary, Anders M Dale, Ole A Andreassen
Importance: Schizophrenia is associated with widespread cognitive impairments. Although cognitive deficits are one of the factors most strongly associated with functional outcome in schizophrenia, current treatment strategies largely fail to ameliorate these impairments. To develop more efficient treatment strategies in patients with schizophrenia, a better understanding of the pathogenesis of these cognitive deficits is needed. Accumulating evidence indicates that genetic risk of schizophrenia may contribute to cognitive dysfunction...
July 26, 2017: JAMA Psychiatry
https://www.readbyqxmd.com/read/28746711/suicidal-behaviors-within-army-units-contagion-and-implications-for-public-health-interventions
#20
Charles W Hoge, Christopher G Ivany, Amy B Adler
No abstract text is available yet for this article.
July 26, 2017: JAMA Psychiatry
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