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JAMA Ophthalmology

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https://www.readbyqxmd.com/read/28426883/challenges-in-the-management-of-fungal-keratitis
#1
Bennie H Jeng
No abstract text is available yet for this article.
April 20, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28426858/improving-more-than-just-vision-in-noninfectious-uveitis
#2
Bryn M Burkholder, Pradeep Y Ramulu
No abstract text is available yet for this article.
April 20, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28426857/spectacle-wear-among-children-in-a-school-based-program-for-ready-made-vs-custom-made-spectacles-in-india-a-randomized-clinical-trial
#3
Priya Morjaria, Jenifer Evans, Kaushik Murali, Clare Gilbert
Importance: Uncorrected refractive errors are the most common cause of visual impairment in children despite correction being highly cost-effective. Objective: To determine whether less expensive ready-made spectacles produce rates of spectacle wear at 3 to 4 months comparable to those of more expensive custom-made spectacles among eligible school-aged children. Design, Setting, and Participants: This noninferiority, double-masked, randomized clinical trial recruited children aged 11 to 15 years from January 12 through July 31, 2015, from government schools in urban and periurban areas surrounding Bangalore, India...
April 20, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28426856/adjunctive-oral-voriconazole-treatment-of-fusarium-keratitis-a-secondary-analysis-from-the-mycotic-ulcer-treatment-trial-ii
#4
N Venkatesh Prajna, Tiruvengada Krishnan, Revathi Rajaraman, Sushila Patel, Ranjeet Shah, Muthiah Srinivasan, Lumbini Devi, Manoranjan Das, Kathryn J Ray, Kieran S O'Brien, Catherine E Oldenburg, Stephen D McLeod, Michael E Zegans, Nisha R Acharya, Thomas M Lietman, Jennifer Rose-Nussbaumer
Importance: Fusarium keratitis is common and often results in poor outcomes. No new treatments since natamycin have become available. Objective: To explore the role of adjuvant oral voriconazole on clinical outcomes in Fusarium keratitis. Design, Setting, and Participants: In this prespecified subgroup analysis of a multicenter, double-masked, placebo-controlled randomized clinical trial, 240 patients from the Aravind Eye Care System in India, the Lumbini Eye Hospital and Bharatpur Eye Hospital in Nepal, and the University of California, San Francisco, who had culture-positive fungal ulcer and baseline visual acuity of 20/400 or worse were randomized to receive oral voriconazole vs placebo...
April 20, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28426852/an-outbreak-of-endogenous-fungal-endophthalmitis-among-intravenous-drug-abusers-in-new-england
#5
Aubrey R Tirpack, Jay S Duker, Caroline R Baumal
Importance: Intravenous drug abuse (IVDA) is a known risk factor for endogenous fungal endophthalmitis (EFE), a severe intraocular infection caused by hematogenous seeding of mycotic organisms to the eye. Reporting significant increases in heroin-related deaths since 2014, the New England region is in the midst of an opioid crisis that has led to a substantial increase in patients at risk for this vision-threatening disease. Objective: To present an update on characteristics, management, and visual outcomes in patients with EFE...
April 20, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28426849/effect-of-adalimumab-on-visual-functioning-in-patients-with-noninfectious-intermediate-uveitis-posterior-uveitis-and-panuveitis-in-the-visual-1-and-visual-2-trials
#6
John Sheppard, Avani Joshi, Keith A Betts, Stacie Hudgens, Samir Tari, Naijun Chen, Martha Skup, Andrew D Dick
Importance: Adalimumab was recently approved for the treatment of noninfectious intermediate uveitis, posterior uveitis, and panuveitis. Objective: To assess the effect of adalimumab on the visual functioning and quality of life in patients with corticosteroid-dependent noninfectious intermediate uveitis, posterior uveitis, and panuveitis. Design: A post hoc analysis of clinical trials of adults with active (VISUAL-1) and inactive (VISUAL-2) noninfectious intermediate uveitis, posterior uveitis, and panuveitis was conducted in the United States, Canada, Europe, Israel, Australia, Latin America, and Japan...
April 20, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28426841/bilateral-retinal-whitening-in-a-hospitalized-patient
#7
Ferhina S Ali, Ehsan Rahimy
No abstract text is available yet for this article.
April 20, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28418539/ophthalmic-manifestations-of-congenital-zika-syndrome-in-colombia-and-venezuela
#8
Juan B Yepez, Felipe A Murati, Michele Pettito, Carlos F Peñaranda, Jazmin de Yepez, Gladys Maestre, J Fernando Arevalo
Importance: The ocular manifestations and sequelae of Zika virus infection are not well known. Recently, the World Health Organization changed the declaration of Zika as a public health emergency and designated the viral outbreak and related microcephaly clusters as a long-term program of work. This change indicates the urgent need to evaluate and document ophthalmic manifestations in patients for timely management of this disease. In addition, confirmation whether the public health problem in Brazil extends to other regions in South America is needed...
April 13, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28418505/acute-and-painless-monocular-vision-loss-in-a-human-immunodeficiency-virus-positive-man
#9
Vinay Kansal, Michael Dollin
No abstract text is available yet for this article.
April 13, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28418500/risk-of-uveitis-among-people-with-psoriasis-a-nationwide-cohort-study
#10
Ching-Chi Chi, Tao-Hsin Tung, Jui Wang, Yu-Sheng Lin, Yu-Fen Chen, Tsui-Kan Hsu, Shu-Hui Wang
Importance: Uveitis has been associated with psoriatic arthritis, but to our knowledge, the relationship between uveitis and psoriasis is unsettled among researchers. Objective: To evaluate the risk of incident uveitis among people with psoriasis. Design, Setting, and Participants: This nationwide, retrospective cohort study conducted in Taiwan from January 1, 2000, to December 31, 2012 included 147 954 people with psoriasis (including 10 107 with concomitant psoriatic arthritis and 137 847 without psoriatic arthritis) and 147 954 nonpsoriatic controls...
April 13, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28418450/the-draw-backs-of-big-data
#11
John A Gonzales, Thomas M Lietman, Nisha R Acharya
No abstract text is available yet for this article.
April 13, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28384778/a-64-year-old-man-with-swollen-blistered-eyelids
#12
Natalie Wolkow, Michael J Yaremchuk, Suzanne K Freitag
No abstract text is available yet for this article.
April 6, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28384676/microscope-integrated-optical-coherence-tomography-angiography-in-the-operating-room-in-young-children-with-retinal-vascular-disease
#13
Xi Chen, Christian Viehland, Oscar M Carrasco-Zevallos, Brenton Keller, Lejla Vajzovic, Joseph A Izatt, Cynthia A Toth
Importance: Intraoperative optical coherence tomography (OCT) has gained traction as an important adjunct for clinical decision making during vitreoretinal surgery, and OCT angiography (OCTA) has provided novel insights in clinical evaluation of retinal diseases. To date, these two technologies have not been applied in combination to evaluate retinal vascular disease in the operating suite. Objective: To conduct microscope-integrated, swept-source OCTA (MIOCTA) in children with retinal vascular disease...
April 6, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28384675/vascular-safety-of-ranibizumab-in-patients-with-diabetic-macular-edema-a-pooled-analysis-of-patient-level-data-from-randomized-clinical-trials
#14
Marco A Zarbin, Cornelia Dunger-Baldauf, Zdenka Haskova, Prashil Koovejee, Marie-Catherine Mousseau, Philippe Margaron, Howard Snow, Paul E Beaumont, Giovanni Staurenghi, Steven Francom
Importance: Patients with diabetic macular edema (DME) are at high risk of vascular complications, including stroke and myocardial infarction (MI). Concerns have been raised that intravitreal dosing of vascular endothelial growth factor inhibitors in DME could be associated with an increase in cardiovascular and cerebrovascular adverse events. Objective: To evaluate the cardiovascular and cerebrovascular safety of ranibizumab, 0.5 mg and 0.3 mg, compared with sham with and without laser in DME...
April 6, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28384671/acute-zonal-cone-photoreceptor-outer-segment-loss
#15
Tomas S Aleman, Harpal S Sandhu, Leona W Serrano, Anastasia Traband, Marisa K Lau, Grazyna Adamus, Robert A Avery
Importance: The diagnostic path presented narrows down the cause of acute vision loss to the cone photoreceptor outer segment and will refocus the search for the cause of similar currently idiopathic conditions. Objective: To describe the structural and functional associations found in a patient with acute zonal occult photoreceptor loss. Design, Setting, and Participants: A case report of an adolescent boy with acute visual field loss despite a normal fundus examination performed at a university teaching hospital...
April 6, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28384654/regression-of-subretinal-lymphoma-after-diagnostic-vitrectomy
#16
Amirreza Pakdel, Zaid Mammo, Hussein Hollands, Farzin Forooghian
No abstract text is available yet for this article.
April 6, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28358967/acute-bilateral-photoreceptor-degeneration-in-an-infant-after-vaccination-against-measles-and-rubella
#17
Kazuki Kuniyoshi, Yoshikazu Hatsukawai, Sadami Kimura, Takahiro Fujino, Hiroshi Ohguro, Rie Nakai, Kenta Sunami, So-Ichiro Mishima, Tomoko Sato, Shunji Kusaka, Yasuhiro Suzuki, Yoshikazu Shimomura
Importance: Ocular inflammation is occasionally observed after vaccinations, and most of them resolve without permanent visual disturbances. However, there are some rare cases of severe ocular complications following vaccinations. Objective: To report the findings in an infant boy who developed an acute loss of vision bilaterally after Haemophilus influenzae type b, Pneumococcal conjugate vaccination, and measles and rubella vaccination. His vision did not recover...
March 30, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28358965/ethnic-differences-in-self-reported-visual-function-among-patients-with-age-related-macular-degeneration-implications-for-care
#18
Lisa Keay
No abstract text is available yet for this article.
March 30, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28358964/treatment-of-previously-refractory-ocular-surface-squamous-neoplasia-with-topical-cidofovir
#19
Matthew H Ip, Minas T Coroneo
No abstract text is available yet for this article.
March 30, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28358963/determining-the-value-of-home-monitoring-of-patients-with-age-related-macular-degeneration
#20
Suzann Pershing, Joshua D Stein
No abstract text is available yet for this article.
March 30, 2017: JAMA Ophthalmology
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