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JAMA Ophthalmology

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https://www.readbyqxmd.com/read/28334414/association-of-a-haplotype-in-the-nr3c2-gene-encoding-the-mineralocorticoid-receptor-with-chronic-central-serous-chorioretinopathy
#1
Elon H C van Dijk, Rosa L Schellevis, Maaike G J M van Bergen, Myrte B Breukink, Lebriz Altay, Paula Scholz, Sascha Fauser, Onno C Meijer, Carel B Hoyng, Anneke I den Hollander, Camiel J F Boon, Eiko K de Jong
Importance: Chronic central serous chorioretinopathy (cCSC) is a chorioretinal disease with unknown disease etiology. The glucocorticoid receptor and the mineralocorticoid receptor, 2 glucocorticoid-binding receptors, might be involved in the pathogenesis of cCSC. Objective: To assess the association of functional variants and haplotypes in the glucocorticoid receptor (NR3C1) and mineralocorticoid receptor (NR3C2) genes with cCSC. Design, Setting, and Participants: In this case-control genetic association study, 336 patients with cCSC and 1314 unaffected controls, collected at 3 university medical centers from September 1, 2009, to May 1, 2016, underwent KASP genotyping for selected variants in NR3C1 (rs56149945, rs41423247, and rs6198) and NR3C2 (rs2070951 and rs5522)...
March 23, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28334364/cerebral-autosomal-dominant-arteriopathy-with-subcortical-infarcts-and-leukoencephalopathy-presenting-with-unilateral-purtscherlike-retinopathy
#2
Irina De la Huerta, Bozho Todorich, Aristomenis Thanos, Sandeep Randhawa
No abstract text is available yet for this article.
March 23, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28334336/ophthalmic-screening-patterns-among-youths-with-diabetes-enrolled-in-a-large-us-managed-care-network
#3
Sophia Y Wang, Chris A Andrews, Thomas W Gardner, Michael Wood, Kanakadurga Singer, Joshua D Stein
Importance: Ophthalmic screening to check for diabetic retinopathy (DR) is important to prevent vision loss in persons with diabetes. The American Academy of Ophthalmology recommends that ophthalmic screening for DR occur beginning at 5 years after initial diabetes diagnosis for youths with type 1 diabetes; the American Diabetes Association recommends screening of youths with type 2 diabetes at the time of initial diagnosis. To our knowledge, it is unknown to what extent youths with diabetes obtain eye examinations in accordance with these guidelines...
March 23, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28334307/an-unusual-corneal-degeneration
#4
Catherine J Choi, Han-Ying Peggy Chang, Nahyoung Grace Lee
No abstract text is available yet for this article.
March 23, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28334299/diabetic-retinopathy-screening-with-telemedicine-a-potential-strategy-to-engage-our-youth
#5
Seema Garg
No abstract text is available yet for this article.
March 23, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28301661/treatment-of-ocular-pyogenic-granuloma-with-topical-timolol
#6
Isdin Oke, Maan Alkharashi, Robert A Petersen, Alena Ashenberg, Ankoor S Shah
Importance: Pyogenic granulomas, acquired vascular lesions, form on the ocular or palpebral surface related to inflammation from chalazia, trauma, or surgery. They can be unsightly, spontaneously bleed, and cause irritation to patients. Observations: A case series is presented of 4 consecutive children with acquired ocular surface pyogenic granulomas treated at Boston Children's Hospital from 2014 to 2016 with only topical timolol, 0.5%, twice daily for a minimum of 21 days...
March 16, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28301651/quantification-of-retinal-microvascular-density-in-optical-coherence-tomographic-angiography-images-in-diabetic-retinopathy
#7
Mary K Durbin, Lin An, Nathan D Shemonski, Mário Soares, Torcato Santos, Marta Lopes, Catarina Neves, Jose Cunha-Vaz
Importance: Quantitative measurements based on optical coherence tomographic angiography (OCTA) may have value in managing diabetic retinopathy (DR), but there is limited information on the ability of OCTA to distinguish eyes with DR. Objective: To evaluate the ability of measurements of retinal microvasculature using OCTA to distinguish healthy eyes from eyes with DR. Design, Setting, and Participants: In this prospective cross-sectional study, OCTA was used to examine the eyes of participants with type 2 diabetes with or without DR and the eyes of participants without diabetes from September 17, 2015, to April 6, 2016...
March 16, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28301650/a-young-woman-with-headaches-and-blurry-vision
#8
Nathan L Scott, Tomasz P Stryjewski, Joseph F Rizzo
No abstract text is available yet for this article.
March 16, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28301649/consensus-on-optical-coherence-tomographic-angiography-nomenclature-do-we-need-to-develop-and-learn-a-new-language
#9
Amani A Fawzi
No abstract text is available yet for this article.
March 16, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28301648/corrections-for-the-abstract-author-affiliations-text-and-a-table
#10
(no author information available yet)
No abstract text is available yet for this article.
March 16, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28301641/uncertainties-in-big-data-when-using-internet-surveillance-tools-and-social-media-for-determining-patterns-in-disease-incidence-reply
#11
Michael S Deiner, Thomas M Lietman, Travis C Porco
No abstract text is available yet for this article.
March 16, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28301640/anti-vegf-injections-and-glaucoma-surgery
#12
Rajendra S Apte, Mae Gordon, Michael A Kass
No abstract text is available yet for this article.
March 16, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28301639/association-of-repeated-intravitreous-bevacizumab-injections-with-risk-for-glaucoma-surgery
#13
Brennan D Eadie, Mahyar Etminan, Bruce C Carleton, David A Maberley, Frederick S Mikelberg
Importance: Intravitreous injections of anti-vascular endothelial growth factor (VEGF) agents are associated with a sustained increase in intraocular pressure. This sustained elevated intraocular pressure could lead to higher rates of glaucoma surgery to lower this pressure. Objective: To determine the risk of glaucoma surgery following repeated intravitreous bevacizumab injections. Design, Setting, Participants: This nested, case-control study acquired and analyzed data from large, population-based, linked health databases supported by the British Columbia Ministry of Health in Canada...
March 16, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28301633/uncertainties-in-big-data-when-using-internet-surveillance-tools-and-social-media-for-determining-patterns-in-disease-incidence
#14
Kurt K Benke
No abstract text is available yet for this article.
March 16, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28278340/corrections-for-text
#15
(no author information available yet)
No abstract text is available yet for this article.
March 9, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28278336/human-leukocyte-antigen-class-i-genes-associated-with-stevens-johnson-syndrome-and-severe-ocular-complications-following-use-of-cold-medicine-in-a-brazilian-population
#16
Tais H Wakamatsu, Mayumi Ueta, Katsushi Tokunaga, Yukinori Okada, Renata R Loureiro, Karita A Costa, Juliana Maria F Sallum, José Arthur Milhomens, Chikara Inoue, Chie Sotozono, José Álvaro P Gomes, Shigeru Kinoshita
Importance: Describing the association with human leukocyte antigen (HLA) alleles could facilitate the understanding of increased risk factors for development of Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) in patients with severe ocular complications (SOCs). Objective: To investigate the association between HLA class I genes and cold medicine (CM)-associated SJS/TEN with SOCs. Design, Setting, and Participants: This case-control study was conducted between February 8, 2013, and August 29, 2014...
March 9, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28278334/retinal-vascular-changes-in-a-young-woman
#17
Ashvini K Reddy
No abstract text is available yet for this article.
March 9, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28278327/chorioretinal-lesions-presumed-secondary-to-zika-virus-infection-in-an-immunocompromised-adult
#18
Christopher R Henry, Luma Al-Attar, Alexis M Cruz-Chacón, Janet L Davis
Importance: Zika virus has spread rapidly throughout the Americas since 2015. The public health implications of Zika virus infection lend special importance to identifying the virus in unsuspected hosts. Objective: To describe relevant imaging studies and clinical features of chorioretinal lesions that are presumably associated with Zika virus and that share analogous features with chorioretinal lesions reported in cases of Dengue fever and West Nile virus. Design, Setting, and Participants: This is a case report from an academic referral center in Miami, Florida, of a woman in her 60s from Guaynabo, Puerto Rico, who presented with reduced visual acuity and bilateral diffuse, subretinal, confluent, placoid, and multifocal chorioretinal lesions...
March 9, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28278325/quantitative-fundus-autofluorescence
#19
Janet R Sparrow
No abstract text is available yet for this article.
March 9, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28278323/quantitative-fundus-autofluorescence-reply
#20
R Theodore Smith
No abstract text is available yet for this article.
March 9, 2017: JAMA Ophthalmology
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