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JAMA Ophthalmology

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https://www.readbyqxmd.com/read/30419128/association-of-long-term-ambient-black-carbon-exposure-and-oxidative-stress-allelic-variants-with-intraocular-pressure-in-older-men
#1
Jamaji C Nwanaji-Enwerem, Weiye Wang, Onyemaechi Nwanaji-Enwerem, Pantel Vokonas, Andrea Baccarelli, Marc Weisskopf, Leon W Herndon, Janey L Wiggs, Sung Kyun Park, Joel Schwartz
Importance: Elevated intraocular pressure is a major risk factor for glaucoma, a leading cause of irreversible blindness worldwide. Environmental air pollution has been suggested as a potential contributor to elevated intraocular pressure; however, no studies have demonstrated such an association to date. Objective: To investigate the association of long-term ambient black carbon exposure with intraocular pressure in community-dwelling older adults. Design, Setting, and Participants: This population-based analysis, conducted from October 18, 2017, through March 22, 2018, used data from the all-male, New England-based Normative Aging Study of the US Department of Veterans Affairs...
November 8, 2018: JAMA Ophthalmology
https://www.readbyqxmd.com/read/30419089/a-potential-link-between-ambient-air-pollution-and-intraocular-pressure
#2
Sahil Thakur, Ching-Yu Cheng
No abstract text is available yet for this article.
November 8, 2018: JAMA Ophthalmology
https://www.readbyqxmd.com/read/30419086/association-of-blepharitis-and-ectropion-with-tumor-necrosis-factor-%C3%AE-inhibitor-treatment-in-crohn-disease
#3
Honeylen Maryl Tiu Teo, Francesca de Sá Freire, Hakan Demirci
No abstract text is available yet for this article.
November 8, 2018: JAMA Ophthalmology
https://www.readbyqxmd.com/read/30419084/association-of-macular-visual-field-measurements-with-glaucoma-staging-systems
#4
Carlos Gustavo De Moraes, Ashley Sun, Ravivarn Jarukasetphon, Rashmi Rajshekhar, Lynn Shi, Dana M Blumberg, Jeffrey M Liebmann, Robert Ritch, Donald C Hood
Importance: Macular function is important for daily activities but is underestimated when tested with 24-2 visual fields, which are often used to classify glaucoma severity. Objective: To test the hypothesis that current glaucoma staging systems underestimate glaucoma severity by not detecting macular damage. Design, Setting, and Participants: This cross-sectional study was carried out in a glaucoma referral practice. The eyes of participants with manifest glaucoma and 24-2 mean deviation (MD) better than -6 dB were included...
November 8, 2018: JAMA Ophthalmology
https://www.readbyqxmd.com/read/30419083/idiopathic-retinal-vasculitis-aneurysms-and-neuroretinitis-irvan-in-a-patient-without-irvan-history
#5
Chandrakumar Balaratnasingam, Lawrence A Yannuzzi, Maria Franchina, K Bailey Freund
No abstract text is available yet for this article.
November 8, 2018: JAMA Ophthalmology
https://www.readbyqxmd.com/read/30419082/comparative-evaluation-of-5-validated-symptom-questionnaires-as-screening-instruments-for-dry-eye-disease
#6
Michael T M Wang, Ally L Xue, Jennifer P Craig
No abstract text is available yet for this article.
November 8, 2018: JAMA Ophthalmology
https://www.readbyqxmd.com/read/30418474/error-in-figure
#7
(no author information available yet)
No abstract text is available yet for this article.
November 8, 2018: JAMA Ophthalmology
https://www.readbyqxmd.com/read/30418470/middle-aged-man-with-bilateral-subretinal-fluid
#8
Kareem Moussa, Michael Bradbury, David M Wu
No abstract text is available yet for this article.
November 8, 2018: JAMA Ophthalmology
https://www.readbyqxmd.com/read/30383168/a-2-year-history-of-diplopia-optic-disc-edema-and-amaurosis
#9
Devon A Cohen, John J Chen, Jacqueline A Leavitt
No abstract text is available yet for this article.
November 1, 2018: JAMA Ophthalmology
https://www.readbyqxmd.com/read/30383166/correction-for-discussion-section
#10
(no author information available yet)
No abstract text is available yet for this article.
November 1, 2018: JAMA Ophthalmology
https://www.readbyqxmd.com/read/30383158/association-of-intravitreal-injections-with-blood-pressure-increase-the-following-excitement-and-anxiety-response-under-intravitreal-injection-study
#11
Vanessa Berger, Marion R Munk, Friedrich Lersch, Sebastian Wolf, Andreas Ebneter, Martin S Zinkernagel
Importance: Despite the unquestionable effectiveness of anti-vascular endothelial growth factor therapy (VEGF), there is ongoing controversy about potential systemic adverse effects. Besides the direct adverse effects of anti-VEGF agents, other factors associated with the injection itself, such as perioperative blood pressure fluctuations, may contribute to adverse events. Objective: To determine blood pressure fluctuations during intravitreal injections. Design, Setting, and Participants: Prospective observational study at a tertiary referral center (Department of Ophthalmology, University Hospital Bern, Bern, Switzerland)...
November 1, 2018: JAMA Ophthalmology
https://www.readbyqxmd.com/read/30383154/association-of-cancer-immunotherapy-with-acute-macular-neuroretinopathy-and-diffuse-retinal-venulitis
#12
Leisha A Emens, S Lindsey Davis, Scott C N Oliver, Christopher H Lieu, Ashvini Reddy, Sharon Solomon, Lingmin He, Roland Morley, Marcella Fassò, Andrea Pirzkall, Hina Patel, Carol O'Hear, Daniela Ferrara
Importance: Checkpoint inhibition in cancer immunotherapy related to T-cell-driven mechanisms of action associated with acute macular neuroretinopathy (AMN) and diffuse retinal venulitis, an adverse event not previously described, is reported here. Objective: To describe 2 patients who developed ophthalmologic events after treatment with the programmed death 1 axis inhibitor, atezolizumab. Design, Setting, and Participants: Retrospective review of 2 patients treated with atezolizumab for metastatic breast cancer and colon cancer, respectively, who presented with AMN and diffuse retinal venulitis conducted at 2 tertiary medical centers...
November 1, 2018: JAMA Ophthalmology
https://www.readbyqxmd.com/read/30422157/donor-recipient-and-operative-factors-associated-with-increased-endothelial-cell-loss-in-the-cornea-preservation-time-study
#13
Jonathan H Lass, Beth Ann Benetz, Sanjay V Patel, Loretta B Szczotka-Flynn, Robert O'Brien, Allison R Ayala, Maureen G Maguire, Yassine J Daoud, Mark A Greiner, Sadeer B Hannush, W Barry Lee, Thomas F Mauger, Harry J Menegay, Mark D Mifflin, Michael B Raizman, Jennifer Rose-Nussbaumer, Robert L Schultze, Gregory A Schmidt, Alan Sugar, Mark A Terry, David D Verdier
Importance: Determining factors associated with endothelial cell loss after Descemet stripping automated endothelial keratoplasty (DSAEK) could improve long-term graft survival. Objective: To evaluate the associations of donor, recipient, and operative factors with endothelial cell density (ECD) 3 years after DSAEK in the Cornea Preservation Time Study. Design, Setting, and Participants: This cohort study was a secondary analysis of data collected in a multicenter, double-masked, randomized clinical trial...
October 26, 2018: JAMA Ophthalmology
https://www.readbyqxmd.com/read/30422231/programming-error-led-to-underestimate-of-effect-sizes-in-study-of-association-of-maternal-preeclampsia-and-risk-of-infant-retinopathy-of-prematurity
#14
Tom Greene, M Elizabeth Hartnett
No abstract text is available yet for this article.
October 25, 2018: JAMA Ophthalmology
https://www.readbyqxmd.com/read/30422230/clinical-features-metastasis-and-survival-in-patients-younger-than-21-years-with-posterior-uveal-melanoma
#15
Matthew V Fry, James J Augsburger, Zélia M Corrêa
Importance: Given the rarity of posterior uveal melanoma in patients younger than 21 years, reporting clinical experience in this area has relevance. Objective: To describe the baseline clinical features, treatment, and clinical course of a group of patients younger than 21 years who have primary posterior uveal melanoma. Design, Setting, and Participants: This retrospective descriptive case series of patients younger than 21 years who have a primary choroidal or ciliochoroidal melanoma was conducted at a single-center subspecialty referral practice...
October 25, 2018: JAMA Ophthalmology
https://www.readbyqxmd.com/read/30422225/association-of-cognitive-impairment-and-dementia-with-receipt-of-cataract-surgery-among-community-dwelling-medicare-beneficiaries
#16
Brian C Stagg, Joshua R Ehrlich, HwaJung Choi, Deborah A Levine
No abstract text is available yet for this article.
October 25, 2018: JAMA Ophthalmology
https://www.readbyqxmd.com/read/30422220/pervasive-errors-in-the-key-points-abstract-results-discussion-table-3-and-etable-in-the-supplement
#17
(no author information available yet)
No abstract text is available yet for this article.
October 25, 2018: JAMA Ophthalmology
https://www.readbyqxmd.com/read/30422218/bilateral-optic-atrophy-in-an-adolescent-male-patient
#18
Priya Sivakumar, Jivitesh Singh, Rajesh Vedachalam
No abstract text is available yet for this article.
October 25, 2018: JAMA Ophthalmology
https://www.readbyqxmd.com/read/30422215/association-of-somatic-gnaq-mutation-with-capillary-malformations-in-a-case-of-choroidal-hemangioma
#19
Colette A Bichsel, Jeremy Goss, Mohammed Alomari, Sanda Alexandrescu, Richard Robb, Lois E Smith, Marcelo Hochman, Arin Greene, Joyce Bischoff
Importance: Choroidal hemangiomas are defined by a thickened choroid owing to vessel overgrowth, which may increase the intraocular pressure and lead to glaucoma. Choroidal hemangioma and glaucoma often co-occur in patients with Sturge-Weber syndrome, a rare neurocutaneous disorder characterized by capillary malformations. Objective: To determine whether the mutation found in most capillary malformations, GNAQ R183Q (c.548G>A), was present in the choroidal hemangioma of a patient with Sturge-Weber syndrome...
October 25, 2018: JAMA Ophthalmology
https://www.readbyqxmd.com/read/30347105/comparison-of-early-treatment-diabetic-retinopathy-study-standard-7-field-imaging-with-ultrawide-field-imaging-for-determining-severity-of-diabetic-retinopathy
#20
Lloyd Paul Aiello, Isoken Odia, Adam R Glassman, Michele Melia, Lee M Jampol, Neil M Bressler, Szilard Kiss, Paolo S Silva, Charles C Wykoff, Jennifer K Sun
Importance: Moderate to substantial agreement between Early Treatment Diabetic Retinopathy Study (ETDRS) 7-field imaging and ultrawide-field (UWF) imaging has been suggested in single-center studies. Comparing images obtained by multiple centers could increase confidence that UWF images can be used reliably in place of ETDRS imaging in future clinical trials. Objective: To compare diabetic retinopathy (DR) severity from modified ETDRS 7-field imaging and UWF imaging...
October 18, 2018: JAMA Ophthalmology
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