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JAMA Ophthalmology

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https://www.readbyqxmd.com/read/28983576/image-averaging-a-powerful-tool-in-optical-coherence-tomography-and-oct-angiography
#1
Nadia K Waheed, Jay S Duker
No abstract text is available yet for this article.
October 5, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28983573/risk-of-intraocular-bleeding-and-the-new-anticoagulants-not-such-a-big-effect
#2
Richard Wormald, Jennifer Evans
No abstract text is available yet for this article.
October 5, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28983572/risk-of-intraocular-bleeding-and-the-new-anticoagulants-not-such-a-big-effect-reply
#3
Michelle T Sun, Christopher X Wong
No abstract text is available yet for this article.
October 5, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28983569/retina-folds-and-subretinal-fluid-after-bell-palsy
#4
Thanos D Papakostas, Giannis A Moustafa, Demetrios G Vavvas
No abstract text is available yet for this article.
October 5, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28983568/ischemic-retinal-vascular-disease-in-an-infant-with-hemophagocytic-lymphohistiocytosis
#5
Avni P Finn, Philip Roehrs, Sara F Grace, Lejla Vajzovic
No abstract text is available yet for this article.
October 5, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28983558/association-between-opioid-prescribing-patterns-and-abuse-in-ophthalmology
#6
Shriji Patel, Paul Sternberg
Importance: Drug overdoses have become the number 1 cause of mortality in American adults 50 years and younger. Prescription opioid abuse is a growing concern that has garnered widespread attention among policymakers and the general public. Objective: To determine the opioid prescribing patterns among ophthalmologists and elucidate their role in the prescription opioid abuse epidemic. Design, Setting, and Participants: In this observational cohort study, beneficiaries and their physicians were analyzed using 2013 to 2015 Medicare Part D Prescriber Data...
October 5, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28983556/efficacy-and-safety-of-ranibizumab-with-or-without-verteporfin-photodynamic-therapy-for-polypoidal-choroidal-vasculopathy-a-randomized-clinical-trial
#7
Adrian Koh, Timothy Y Y Lai, Kanji Takahashi, Tien Y Wong, Lee-Jen Chen, Paisan Ruamviboonsuk, Colin S Tan, Chrystel Feller, Philippe Margaron, Tock H Lim, Won Ki Lee
Importance: Polypoidal choroidal vasculopathy (PCV) is a common subtype of exudative age-related macular degeneration among Asian individuals. To our knowledge, there are no large randomized clinical trials to evaluate intravitreal ranibizumab, with and without verteporfin photodynamic therapy (vPDT), for the treatment of PCV. Objective: To compare the efficacy and safety of combination therapy of ranibizumab and vPDT with ranibizumab monotherapy in PCV. Design, Setting, and Participants: A double-masked, multicenter randomized clinical trial of 322 Asian participants with symptomatic macular PCV confirmed by the Central Reading Center using indocyanine green angiography was conducted between August 7, 2013, and March 2, 2017...
October 5, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28983554/adopting-the-results-of-everest-ii-into-practice-a-clearer-view-from-a-higher-level-study
#8
David J Browning
No abstract text is available yet for this article.
October 5, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28983552/choriocapillaris-imaging-using-multiple-en-face-optical-coherence-tomography-angiography-image-averaging
#9
Akihito Uji, Siva Balasubramanian, Jianqin Lei, Elmira Baghdasaryan, Mayss Al-Sheikh, SriniVas R Sadda
Importance: Imaging of the choriocapillaris in vivo is challenging with existing technology. Optical coherence tomography angiography (OCTA), if optimized, could make the imaging less challenging. Objective: To investigate multiple en face image averaging on OCTA images of the choriocapillaris. Design, Setting, and Participants: Observational, cross-sectional case series at a referral institutional practice in Los Angeles, California. From the original cohort of 21 healthy individuals, 17 normal eyes of 17 participants were included in the study...
October 5, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28973538/choroidal-features-of-acute-macular-neuroretinopathy-via-optical-coherence-tomography-angiography-and-correlation-with-serial-multimodal-imaging
#10
Sun Young Lee, Justine L Cheng, Karen M Gehrs, James C Folk, Elliott H Sohn, Stephen R Russell, Zhihui Guo, Michael D Abràmoff, Ian C Han
Importance: Acute macular neuroretinopathy (AMN) is a rare, idiopathic condition resembling other acute maculopathies such as paracentral acute middle maculopathy. The pathophysiology of AMN is not well understood, and the role of the choroid in the pathogenesis of AMN remains controversial. Objective: To describe initial and serial multimodal imaging findings in AMN, with attention to choroidal vascular changes. Design, Setting, and Participants: Retrospective case series at a single institution, tertiary referral center...
September 28, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28973295/surveillance-surveys-for-reemergent-trachoma-in-formerly-endemic-districts-in-nepal-from-2-to-10-years-after-mass-drug-administration-cessation
#11
Sheila K West, Andrea I Zambrano, Shekhar Sharma, Sailesh K Mishra, Beatriz E Muñoz, Laura Dize, Kathryn Crowley, Charlotte A Gaydos, Lisa A Rotondo
Importance: To verify districts for elimination of blinding trachoma, the World Health Organization requires a population-based surveillance survey for follicular trachoma (TF) and trachomatous trichiasis (TT) 2 years after mass drug administration (MDA) activities have ceased. However, it is unknown if 2 years provides enough time to discover reemergence. Objective: To determine the prevalence of trachoma from surveys among 4 districts in Nepal (Dailekh, Dang, Surkhet, and Kanchanpur) that had surveillance intervals of 2, 4, 8, and 10 years, respectively, after cessation of MDA...
September 28, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28973285/a-neonate-with-acute-dacryocystitis
#12
Nicholas A Moore, Rao V Chundury
No abstract text is available yet for this article.
September 28, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28973143/the-role-of-macular-pigment-density-measures-in-future-clinical-studies-of-age-related-macular-degeneration
#13
Anne S Lindblad
No abstract text is available yet for this article.
September 28, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28973097/association-between-fungal-contamination-and-eye-bank-prepared-endothelial-keratoplasty-tissue-temperature-dependent-risk-factors-and-antifungal-supplementation-of-optisol-gentamicin-and-streptomycin
#14
Kimberly M Brothers, Robert M Q Shanks, Susan Hurlbert, Regis P Kowalski, Elmer Y Tu
Importance: Fungal contamination and infection from donor tissues processed for endothelial keratoplasty is a growing concern, prompting analysis of donor tissues after processing. Objective: To determine whether eyebank-processed endothelial keratoplasty tissue is at higher risk of contamination than unprocessed tissue and to model eyebank processing with regard to room temperature exposure on Candida growth in optisol-gentamicin and streptomycin (GS) with and without antifungal supplementation...
September 28, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28973096/automated-grading-of-age-related-macular-degeneration-from-color-fundus-images-using-deep-convolutional-neural-networks
#15
Philippe M Burlina, Neil Joshi, Michael Pekala, Katia D Pacheco, David E Freund, Neil M Bressler
Importance: Age-related macular degeneration (AMD) affects millions of people throughout the world. The intermediate stage may go undetected, as it typically is asymptomatic. However, the preferred practice patterns for AMD recommend identifying individuals with this stage of the disease to educate how to monitor for the early detection of the choroidal neovascular stage before substantial vision loss has occurred and to consider dietary supplements that might reduce the risk of the disease progressing from the intermediate to the advanced stage...
September 28, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28973076/effect-of-dietary-supplementation-with-lutein-zeaxanthin-and-%C3%AF-3-on-macular-pigment-a-randomized-clinical-trial
#16
Jean-François Korobelnik, Marie-Bénédicte Rougier, Marie-Noëlle Delyfer, Alain Bron, Bénédicte M J Merle, Hélène Savel, Geneviève Chêne, Cécile Delcourt, Catherine Creuzot-Garcher
Importance: Nutritional uptake of lutein, zeaxanthin, and ω-3 polyunsaturated fatty acids may increase macular pigment optical density (MPOD) and thereby protect against the development of age-related macular degeneration (AMD). Objectives: To estimate the efficiency of dietary supplementation containing lutein, zeaxanthin, ω-3 polyunsaturated fatty acids, and vitamins to increase the density of macular pigment in first-generation offspring of parents with neovascular AMD...
September 28, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28975281/genotype-phenotype-associations-of-il6-and-prg4-with-conjunctival-fibrosis-after-glaucoma-surgery
#17
Cynthia Yu-Wai-Man, Aristides D Tagalakis, Jinhong Meng, Yann Bouremel, Richard M H Lee, Alex Virasami, Stephen L Hart, Peng T Khaw
Importance: Postsurgical fibrosis is a critical determinant of the long-term success of glaucoma surgery, but no reliable biomarkers are currently available to stratify the risk of scarring. Objective: To compare the clinical phenotype of patients with conjunctival fibrosis after glaucoma surgery with candidate gene expression tissue biomarkers of fibrosis. Design, Setting, and Participants: In this cross-sectional study, 42 patients were recruited at the time of glaucoma surgery at the Moorfields Eye Hospital from September 1, 2014, to September 1, 2016...
September 21, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28975251/melanoma-associated-retinopathy-28-years-after-diagnosis
#18
Jack J Tian, Stuart Coupland, Rustum Karanjia, Alfredo A Sadun
No abstract text is available yet for this article.
September 21, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28975236/gene-expression-profiling-and-heterogeneity-of-nonspecific-orbital-inflammation-affecting-the-lacrimal-gland
#19
James T Rosenbaum, Dongseok Choi, Christina A Harrington, David J Wilson, Hans E Grossniklaus, Cailin H Sibley, Sherveen S Salek, John D Ng, Roger A Dailey, Eric A Steele, Brent Hayek, Caroline M Craven, Deepak P Edward, Azza M Y Maktabi, Hailah Al Hussain, Valerie A White, Peter J Dolman, Craig N Czyz, Jill A Foster, Gerald J Harris, Youn-Shen Bee, David T Tse, Chrisfouad R Alabiad, Sander R Dubovy, Michael Kazim, Dinesh Selva, R Patrick Yeatts, Bobby S Korn, Don O Kikkawa, Rona Z Silkiss, Jennifer A Sivak-Callcott, Patrick Stauffer, Stephen R Planck
Importance: Although a variety of well-characterized diseases, such as sarcoidosis and granulomatosis with polyangiitis, affect the lacrimal gland, many patients with dacryoadenitis are diagnosed as having nonspecific orbital inflammation (NSOI) on the basis of histology and systemic disease evaluation. The ability to further classify the disease in these patients should facilitate selection of effective therapies. Objective: To test the a priori hypothesis that gene expression profiles would complement clinical and histopathologic evaluations in identifying well-characterized diseases and in subdividing NSOI into clinically relevant groups...
September 21, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28975233/metallic-filament-embolization-of-the-retinal-artery
#20
Hossein Nazari, Mai Kim-Binh, Sushma Yalamanchili, Emmanuel Chang
No abstract text is available yet for this article.
September 21, 2017: JAMA Ophthalmology
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