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JAMA Neurology

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https://www.readbyqxmd.com/read/29049812/mild-traumatic-brain-injury-and-mental-health-reply
#1
Christine L Mac Donald, Jesse R Fann, Nancy R Temkin
No abstract text is available yet for this article.
October 16, 2017: JAMA Neurology
https://www.readbyqxmd.com/read/29049519/association-of-bone-mineral-density-with-the-risk-of-intracranial-aneurysm
#2
Yong-Won Shin, Kyung-Il Park, Jangsup Moon, Soon-Tae Lee, Kon Chu, Sang Kun Lee, Jae-Kyu Roh, Keun-Hwa Jung
Importance: Disruption of extracellular matrix integrity is critically involved in both intracranial aneurysm and bone fragility. Furthermore, both intracranial aneurysm and osteoporosis have a female predominance, and sex hormones are considered to affect this discrepancy. Objective: To evaluate the association between bone mineral density and intracranial aneurysm. Design, Setting, and Participants: A cross-sectional study conducted with 14 328 patients who underwent brain magnetic resonance angiography and bone mineral densitometry as a part of a health examination at a specialized center for comprehensive health examination in Seoul, the largest metropolitan area in the Republic of Korea, between December 2004 and November 2015...
October 16, 2017: JAMA Neurology
https://www.readbyqxmd.com/read/29049480/interpreting-biomarker-results-in-individual-patients-with-mild-cognitive-impairment-in-the-alzheimer-s-biomarkers-in-daily-practice-abide-project
#3
Ingrid S van Maurik, Marissa D Zwan, Betty M Tijms, Femke H Bouwman, Charlotte E Teunissen, Philip Scheltens, Mike P Wattjes, Frederik Barkhof, Johannes Berkhof, Wiesje M van der Flier
Importance: Biomarkers do not determine conversion to Alzheimer disease (AD) perfectly, and criteria do not specify how to take patient characteristics into account. Consequently, biomarker use may be challenging for clinicians, especially in patients with mild cognitive impairment (MCI). Objective: To construct biomarker-based prognostic models that enable determination of future AD dementia in patients with MCI. Design, Setting, and Participants: This study is part of the Alzheimer's Biomarkers in Daily Practice (ABIDE) project...
October 16, 2017: JAMA Neurology
https://www.readbyqxmd.com/read/29049479/dual-task-gait-and-incident-dementia-a-step-forward-but-not-there-yet-reply
#4
Manuel Montero-Odasso, Richard Camicioli, Susan W Muir-Hunter
No abstract text is available yet for this article.
October 16, 2017: JAMA Neurology
https://www.readbyqxmd.com/read/29049464/clustering-of-neuropsychiatric-disease-in-first-degree-and-second-degree-relatives-of-patients-with-amyotrophic-lateral-sclerosis
#5
Margaret O'Brien, Tom Burke, Mark Heverin, Alice Vajda, Russell McLaughlin, John Gibbons, Susan Byrne, Marta Pinto-Grau, Marwa Elamin, Niall Pender, Orla Hardiman
Importance: Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative condition primarily involving the motor system. There is increasing epidemiologic evidence of an association between ALS and a wider spectrum of neurodegenerative and neuropsychiatric disorders among family members, including schizophrenia and psychotic illness and suicidal behavior. Objective: To examine the frequency and range of neuropsychiatric conditions that occur within individual first-degree and second-degree relatives of patients with ALS...
October 16, 2017: JAMA Neurology
https://www.readbyqxmd.com/read/29049460/mild-traumatic-brain-injury-and-mental-health
#6
Lt Alfred G Smith, Lt Benjamin S Vipler
No abstract text is available yet for this article.
October 16, 2017: JAMA Neurology
https://www.readbyqxmd.com/read/29049450/dual-task-gait-and-incident-dementia-a-step-forward-but-not-there-yet
#7
Sirwan K L Darweesh, Vincentius J A Verlinden, M Arfan Ikram
No abstract text is available yet for this article.
October 16, 2017: JAMA Neurology
https://www.readbyqxmd.com/read/29049449/increasing-evidence-for-an-association-between-amyotrophic-lateral-sclerosis-and-psychiatric-disorders
#8
Miguel Chuquilin, Susan Wymer, James Wymer
No abstract text is available yet for this article.
October 16, 2017: JAMA Neurology
https://www.readbyqxmd.com/read/29052703/xp22-2-chromosomal-duplication-in-familial-intracranial-arachnoid-cyst
#9
Charuta G Furey, Andrew T Timberlake, Carol Nelson-Williams, Daniel Duran, Peining Li, Eric M Jackson, Kristopher T Kahle
No abstract text is available yet for this article.
October 10, 2017: JAMA Neurology
https://www.readbyqxmd.com/read/29052732/a-novel-clinical-score-to-assess-seizure-risk
#10
Barry M Czeisler, Jan Claassen
No abstract text is available yet for this article.
October 9, 2017: JAMA Neurology
https://www.readbyqxmd.com/read/29052731/demystifying-neurosarcoidosis-and-informing-prognosis
#11
Jeffrey M Gelfand
No abstract text is available yet for this article.
October 9, 2017: JAMA Neurology
https://www.readbyqxmd.com/read/29052723/death-by-gun-violence-a-public-health-crisis
#12
Howard Bauchner, Frederick P Rivara, Robert O Bonow, Neil M Bressler, Mary L Nora Disis, Stephan Heckers, S Andrew Josephson, Melina R Kibbe, Jay F Piccirillo, Rita F Redberg, John S Rhee, June K Robinson
No abstract text is available yet for this article.
October 9, 2017: JAMA Neurology
https://www.readbyqxmd.com/read/29052709/association-of-prognostic-factors-and-immunosuppressive-treatment-with-long-term-outcomes-in-neurosarcoidosis
#13
Bastien Joubert, Catherine Chapelon-Abric, Lucie Biard, David Saadoun, Sophie Demeret, Didier Dormont, Matthieu Resche-Rigon, Patrice Cacoub
Importance: Prognostic factors are lacking in neurosarcoidosis (NS), and the association of immunosuppressive treatments with outcomes are unclear. Objectives: To identify prognostic factors of and analyze the association of immunosuppressive treatment with relapse of NS. Design, Setting, and Participants: In this retrospective study, a cohort of 234 patients fulfilled the diagnostic criteria for NS in a tertiary referral center in Paris, France, from January 1, 1990, through December 31, 2015...
October 9, 2017: JAMA Neurology
https://www.readbyqxmd.com/read/29052706/association-of-an-electroencephalography-based-risk-score-with-seizure-probability-in-hospitalized-patients
#14
Aaron F Struck, Berk Ustun, Andres Rodriguez Ruiz, Jong Woo Lee, Suzette M LaRoche, Lawrence J Hirsch, Emily J Gilmore, Jan Vlachy, Hiba Arif Haider, Cynthia Rudin, M Brandon Westover
Importance: Continuous electroencephalography (EEG) use in critically ill patients is expanding. There is no validated method to combine risk factors and guide clinicians in assessing seizure risk. Objective: To use seizure risk factors from EEG and clinical history to create a simple scoring system associated with the probability of seizures in patients with acute illness. Design, Setting, and Participants: We used a prospective multicenter (Emory University Hospital, Brigham and Women's Hospital, and Yale University Hospital) database containing clinical and electrographic variables on 5427 continuous EEG sessions from eligible patients if they had continuous EEG for clinical indications, excluding epilepsy monitoring unit admissions...
October 9, 2017: JAMA Neurology
https://www.readbyqxmd.com/read/29052699/overall-survival-and-causes-of-death-in-neurodegeneration-an-overlooked-and-underreported-theme
#15
Filipe B Rodrigues, Joaquim J Ferreira
No abstract text is available yet for this article.
October 9, 2017: JAMA Neurology
https://www.readbyqxmd.com/read/29052695/alternating-horner-syndrome-with-vegetative-alterna-and-spastic-quadraparesis-after-bacterial-meningitis
#16
Adrian Budhram, Mary Feng, Rookaya Mather, Donald H Lee, Dwight E Moulin
No abstract text is available yet for this article.
October 9, 2017: JAMA Neurology
https://www.readbyqxmd.com/read/29052692/overall-survival-and-causes-of-death-in-neurodegeneration-an-overlooked-and-underreported-theme-reply
#17
Rodolfo Savica, Michelle M Mielke
No abstract text is available yet for this article.
October 9, 2017: JAMA Neurology
https://www.readbyqxmd.com/read/29052688/risk-of-tinnitus-after-medial-temporal-lobe-surgery
#18
Sébastien Paquette, Philippe Fournier, Sophie Dupont, Fabien Szabo de Edelenyi, Pilar Galan, Séverine Samson
No abstract text is available yet for this article.
October 9, 2017: JAMA Neurology
https://www.readbyqxmd.com/read/28973551/region-specific-association-of-subjective-cognitive-decline-with-tauopathy-independent-of-global-%C3%AE-amyloid-burden
#19
Rachel F Buckley, Bernard Hanseeuw, Aaron P Schultz, Patrizia Vannini, Sarah L Aghjayan, Michael J Properzi, Jonathan D Jackson, Elizabeth C Mormino, Dorene M Rentz, Reisa A Sperling, Keith A Johnson, Rebecca E Amariglio
Importance: The ability to explore associations between reports of subjective cognitive decline (SCD) and biomarkers of early Alzheimer disease (AD) pathophysiologic processes (accumulation of neocortical β-amyloid [Aβ] and tau) provides an important opportunity to understand the basis of SCD and AD risk. Objective: To examine associations between SCD and global Aβ and tau burdens in regions of interest in clinically healthy older adults. Design, Setting, and Participants: This imaging substudy of the Harvard Aging Brain Study included 133 clinically healthy older participants (Clinical Dementia Rating Scale global scores of 0) participating in the Harvard Aging Brain Study who underwent cross-sectional flortaucipir F 18 (previously known as AV 1451, T807) positron emission tomography (FTP-PET) imaging for tau and Pittsburgh compound B carbon 11-labeled PET (PiB-PET) imaging for Aβ...
October 2, 2017: JAMA Neurology
https://www.readbyqxmd.com/read/28973174/low-dose-vs-standard-dose-alteplase-for-patients-with-acute-ischemic-stroke-secondary-analysis-of-the-enchanted-randomized-clinical-trial
#20
Xia Wang, Thompson G Robinson, Tsong-Hai Lee, Qiang Li, Hisatomi Arima, Philip M Bath, Laurent Billot, Joseph Broderick, Andrew M Demchuk, Geoffrey Donnan, Jong S Kim, Pablo Lavados, Richard I Lindley, Sheila O Martins, Veronica V Olavarria, Jeyaraj D Pandian, Mark W Parsons, Octavio M Pontes-Neto, Stefano Ricci, Vijay K Sharma, Nguyen H Thang, Ji-Guang Wang, Mark Woodward, Craig S Anderson, John Chalmers
Importance: A lower dose of intravenous alteplase appears to be a safer treatment option than the standard dose, reducing the risk of symptomatic intracerebral hemorrhage. There is uncertainty, however, over how this effect translates into an overall clinical benefit for patients with acute ischemic stroke (AIS). Objective: To assess whether older, Asian, or severely affected patients with AIS who are considered at high risk of thrombolysis may benefit more from low-dose rather than standard-dose alteplase treatment...
October 2, 2017: JAMA Neurology
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