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JAMA Internal Medicine

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https://www.readbyqxmd.com/read/28437544/polypharmacy-in-the-elderly-when-good-drugs-lead-to-bad-outcomes-a-teachable-moment
#1
Casey Carroll, Ahmed Hassanin
No abstract text is available yet for this article.
April 24, 2017: JAMA Internal Medicine
https://www.readbyqxmd.com/read/28437543/association-of-donor-age-and-sex-with-survival-of-patients-receiving-transfusions
#2
Gustaf Edgren, Henrik Ullum, Klaus Rostgaard, Christian Erikstrup, Ulrik Sartipy, Martin J Holzmann, Olof Nyrén, Henrik Hjalgrim
Importance: Following animal model data indicating the possible rejuvenating effects of blood from young donors, there have been at least 2 observational studies conducted with humans that have investigated whether donor age affects patient outcomes. Results, however, have been conflicting. Objective: To study the association of donor age and sex with survival of patients receiving transfusions. Design, Setting, and Participants: A retrospective cohort study based on the Scandinavian Donations and Transfusions database, with nationwide data, was conducted for all patients from Sweden and Denmark who received at least 1 red blood cell transfusion of autologous blood or blood from unknown donors between January 1, 2003, and December 31, 2012...
April 24, 2017: JAMA Internal Medicine
https://www.readbyqxmd.com/read/28437539/safety-and-efficacy-of-antiviral-therapy-for-prevention-of-cytomegalovirus-reactivation-in-immunocompetent-critically-ill-patients-a-randomized-clinical-trial
#3
Nicholas J Cowley, Andrew Owen, Sarah C Shiels, Joanne Millar, Rebecca Woolley, Natalie Ives, Husam Osman, Paul Moss, Julian F Bion
Importance: Latent cytomegalovirus (CMV) infection is present in more than half the adult population, and a viral reactivation (ie, when the virus becomes measurable in body fluids such as blood) can occur in up to one-third of these individuals during episodes of critical illness. Objective: To determine whether antiviral therapy is safe and effective for preventing CMV reactivation in a general population of critically ill patients. Design, Setting, and Participants: A single-center, open-label, randomized, controlled clinical trial recruited 124 CMV-seropositive patients undergoing mechanical ventilation for at least 24 hours in the intensive care unit between January 1, 2012, and January 31, 2014...
April 24, 2017: JAMA Internal Medicine
https://www.readbyqxmd.com/read/28437537/recent-patterns-of-prostate-specific-antigen-testing-for-prostate-cancer-screening-in-the-united-states
#4
Stacey A Fedewa, Elizabeth M Ward, Otis Brawley, Ahmedin Jemal
No abstract text is available yet for this article.
April 24, 2017: JAMA Internal Medicine
https://www.readbyqxmd.com/read/28437532/the-value-of-using-registries-to-evaluate-randomized-clinical-trial-study-populations
#5
Adam J Schoenfeld, Rita F Redberg
No abstract text is available yet for this article.
April 24, 2017: JAMA Internal Medicine
https://www.readbyqxmd.com/read/28437531/applicability-of-the-improve-it-trial-to-current-patients-with-acute-coronary-syndrome-an-ncdr-research-to-practice-project
#6
Thomas M Maddox, Fengming Tang, John R Downs, Frederick A Masoudi, Salim S Virani, Stacie L Daugherty, John S Rumsfeld
No abstract text is available yet for this article.
April 24, 2017: JAMA Internal Medicine
https://www.readbyqxmd.com/read/28437523/emergency-department-query-for-patient-centered-approaches-to-sexual-orientation-and-gender-identity-the-equality-study
#7
Adil H Haider, Eric B Schneider, Lisa M Kodadek, Rachel R Adler, Anju Ranjit, Maya Torain, Ryan Y Shields, Claire Snyder, Jeremiah D Schuur, Laura Vail, Danielle German, Susan Peterson, Brandyn D Lau
Importance: The Institute of Medicine and The Joint Commission recommend routine documentation of patients' sexual orientation in health care settings. Currently, very few health care systems collect these data since patient preferences and health care professionals' support regarding collection of data about patient sexual orientation are unknown. Objective: To identify the optimal patient-centered approach to collect sexual orientation data in the emergency department (ED) in the Emergency Department Query for Patient-Centered Approaches to Sexual Orientation and Gender Identity study...
April 24, 2017: JAMA Internal Medicine
https://www.readbyqxmd.com/read/28437522/statistical-caution-in-big-data-approaches-to-transfusion-medicine-research
#8
Nareg Roubinian, Donald Brambilla, Edward L Murphy
No abstract text is available yet for this article.
April 24, 2017: JAMA Internal Medicine
https://www.readbyqxmd.com/read/28437517/the-tension-between-promoting-mobility-and-preventing-falls-in-the-hospital
#9
Matthew E Growdon, Ronald I Shorr, Sharon K Inouye
No abstract text is available yet for this article.
April 24, 2017: JAMA Internal Medicine
https://www.readbyqxmd.com/read/28430829/effect-of-a-price-transparency-intervention-in-the-electronic-health-record-on-clinician-ordering-of-inpatient-laboratory-tests-the-price-randomized-clinical-trial
#10
Mina S Sedrak, Jennifer S Myers, Dylan S Small, Irving Nachamkin, Justin B Ziemba, Dana Murray, Gregory W Kurtzman, Jingsan Zhu, Wenli Wang, Deborah Mincarelli, Daniel Danoski, Brian P Wells, Jeffrey S Berns, Patrick J Brennan, C William Hanson, C Jessica Dine, Mitesh S Patel
Importance: Many health systems are considering increasing price transparency at the time of order entry. However, evidence of its impact on clinician ordering behavior is inconsistent and limited to single-site evaluations of shorter duration. Objective: To test the effect of displaying Medicare allowable fees for inpatient laboratory tests on clinician ordering behavior over 1 year. Design, Setting, and Participants: The Pragmatic Randomized Introduction of Cost data through the electronic health record (PRICE) trial was a randomized clinical trial comparing a 1-year intervention to a 1-year preintervention period, and adjusting for time trends and patient characteristics...
April 21, 2017: JAMA Internal Medicine
https://www.readbyqxmd.com/read/28430828/achieving-the-promise-of-price-transparency
#11
Anna D Sinaiko, Alyna T Chien
No abstract text is available yet for this article.
April 21, 2017: JAMA Internal Medicine
https://www.readbyqxmd.com/read/28418530/hiding-in-plain-sight-resurrecting-the-power-of-inspecting-the-patient
#12
Shlok Gupta, Sanjay Saint, Allan S Detsky
No abstract text is available yet for this article.
April 17, 2017: JAMA Internal Medicine
https://www.readbyqxmd.com/read/28418527/initial-public-reporting-of-quality-at-veterans-affairs-vs-non-veterans-affairs-hospitals
#13
Eddie Blay, John Oliver DeLancey, D Brock Hewitt, Jeanette W Chung, Karl Y Bilimoria
No abstract text is available yet for this article.
April 17, 2017: JAMA Internal Medicine
https://www.readbyqxmd.com/read/28418525/asymptomatic-microscopic-hematuria-rethinking-the-diagnostic-algorithm
#14
Leslee L Subak, Deborah Grady
No abstract text is available yet for this article.
April 17, 2017: JAMA Internal Medicine
https://www.readbyqxmd.com/read/28418511/early-palliative-care-in-advanced-illness-do-right-by-mama
#15
Anand S Iyer, Marie Bakitas
No abstract text is available yet for this article.
April 17, 2017: JAMA Internal Medicine
https://www.readbyqxmd.com/read/28418451/cost-effectiveness-of-common-diagnostic-approaches-for-evaluation-of-asymptomatic-microscopic-hematuria
#16
Joshua A Halpern, Bilal Chughtai, Hassan Ghomrawi
Importance: Asymptomatic microscopic hematuria (AMH) is highly prevalent and may signal occult genitourinary (GU) malignant abnormality. Common diagnostic approaches differ in their costs and effectiveness in detecting cancer. Given the low prevalence of GU malignant abnormality among patients with AMH, it is important to quantify the cost implications of detecting cancer for each approach. Objective: To estimate the effectiveness, costs, and incremental cost per cancer detected (ICCD) for 4 common diagnostic approaches evaluating AMH...
April 17, 2017: JAMA Internal Medicine
https://www.readbyqxmd.com/read/28418449/association-of-a-communication-training-program-with-use-of-antipsychotics-in-nursing-homes
#17
Jennifer Tjia, Jacob N Hunnicutt, Laurie Herndon, Carolyn R Blanks, Kate L Lapane, Susan Wehry
Importance: Off-label antipsychotic prescribing in nursing homes (NHs) is common and is associated with increased risk of mortality in older adults. Prior large-scale, controlled trials in the NH setting failed to show meaningful reductions in antipsychotic use. Objective: To quantify the influence of a large-scale communication training program on NH antipsychotic use called OASIS. Design, Setting, and Participants: This investigation was a quasi-experimental longitudinal study of NHs in Massachusetts enrolled in the OASIS intervention...
April 17, 2017: JAMA Internal Medicine
https://www.readbyqxmd.com/read/28418448/%C3%AE-blocker-exposure-in-pregnancy-and-risk-of-fetal-cardiac-anomalies
#18
Lewei Duan, Angie Ng, Wansu Chen, Hillard T Spencer, Jennifer Nguyen, Albert Y-J Shen, Ming-Sum Lee
No abstract text is available yet for this article.
April 17, 2017: JAMA Internal Medicine
https://www.readbyqxmd.com/read/28418446/anticoagulation-reversal-for-supratherapeutic-international-normalized-ratio-a-teachable-moment
#19
Sri Lekha Tummalapalli, Yue Qiu, Hyung J Cho
No abstract text is available yet for this article.
April 17, 2017: JAMA Internal Medicine
https://www.readbyqxmd.com/read/28395063/physician-adherence-to-breast-cancer-screening-recommendations
#20
Deborah Grady, Rita F Redberg
No abstract text is available yet for this article.
April 10, 2017: JAMA Internal Medicine
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