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JAMA Dermatology

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https://www.readbyqxmd.com/read/28980004/brentuximab-vedotin-for-patients-with-refractory-lymphomatoid-papulosis-an-analysis-of-phase-2-results
#1
Daniel J Lewis, Rakhshandra Talpur, Auris O Huen, Michael T Tetzlaff, Madeleine Duvic
Importance: Brentuximab vedotin is a monomethyl auristatin E-conjugated monoclonal antibody directed against CD30. It represents a potential treatment for the CD30+ lymphoproliferative disorder lymphomatoid papulosis (LyP), which currently has no approved treatment. Objective: To assess the efficacy and safety of brentuximab vedotin for the treatment of LyP. Design, Setting, and Participants: In this study conducted at The University of Texas MD Anderson Cancer Center from May 10, 2011, to March 31, 2017, a total of 12 patients with LyP received brentuximab vedotin...
October 4, 2017: JAMA Dermatology
https://www.readbyqxmd.com/read/28979983/delay-and-disparity-in-time-to-surgical-treatment-for-melanoma
#2
Jason P Lott
No abstract text is available yet for this article.
October 4, 2017: JAMA Dermatology
https://www.readbyqxmd.com/read/28979974/association-of-delays-in-surgery-for-melanoma-with-insurance-type
#3
Adewole S Adamson, Lei Zhou, Christopher D Baggett, Nancy E Thomas, Anne-Marie Meyer
Importance: Timely receipt of treatment for cancer is an important aspect of health care quality. It is unknown how delays of surgery for melanoma vary by insurance type. Objective: To analyze factors associated with delays between diagnosis and surgery for melanoma in patients with Medicare, Medicaid, or private insurance. Design, Setting, and Participants: Retrospective cohort study of patients who received a diagnosis of melanoma between 2004 and 2011 in North Carolina using data from the North Carolina Cancer Registry linked to administrative claims from Medicare, Medicaid, and private insurance...
October 4, 2017: JAMA Dermatology
https://www.readbyqxmd.com/read/28979973/human-papillomavirus-induced-atypical-pigmented-high-grade-dysplasia-of-the-scrotum
#4
Alexander Kreuter, Steffi Silling, Frank Oellig, Ulrike Wieland
No abstract text is available yet for this article.
October 4, 2017: JAMA Dermatology
https://www.readbyqxmd.com/read/28979971/treatment-of-psychiatric-disorders-and-skin-restricted-lupus-remission-a-longitudinal-study
#5
Isabelle Jalenques, Fabien Rondepierre, Catherine Massoubre, Bruno Labeille, Jean-Luc Perrot, Aurélien Mulliez, Michel D'Incan
No abstract text is available yet for this article.
October 4, 2017: JAMA Dermatology
https://www.readbyqxmd.com/read/28973428/chronic-urticaria-in-children-still-itching-for-insight
#6
Marcus Maurer, Martin K Church, Karsten Weller
No abstract text is available yet for this article.
September 27, 2017: JAMA Dermatology
https://www.readbyqxmd.com/read/28973414/sclerotherapy-for-reticular-veins-in-the-lower-limbs-a-triple-blind-randomized-clinical-trial
#7
Matheus Bertanha, Rodrigo Gibin Jaldin, Regina Moura, Rafael Elias Farres Pimenta, Jamil Victor de Oliveira Mariúba, Carlos Eduardo Pinheiro Lúcio Filho, Giovana Piteri Alcantara, Carlos Roberto Padovani, Winston Bonetti Yoshida, Marcone Lima Sobreira
Importance: Reticular veins are subdermal veins located in the lower limbs and are mainly associated with aesthetic complaints. Although sclerotherapy is the treatment of choice for reticular veins in the lower limbs, no consensus has been reached regarding to the optimal sclerosant. Objective: To compare the efficacy and safety of 2 sclerosants used to treat reticular veins: 0.2% polidocanol diluted in 70% hypertonic glucose (HG) (group 1) vs 75% HG alone (group 2)...
September 27, 2017: JAMA Dermatology
https://www.readbyqxmd.com/read/28973128/screening-guidelines-for-thyroid-function-in-children-with-alopecia-areata
#8
Deepa Patel, Ping Li, Andrew J Bauer, Leslie Castelo-Soccio
Importance: The incidence of thyroid disease in children with alopecia areata (AA) has been widely studied with no consensus on whether a true association with AA exists. In addition, screening practices for thyroid dysfunction in children with AA vary widely among clinicians. Objective: To reduce health care costs, eliminate unnecessary testing, and standardize clinical practices, we sought to to characterize thyroid function in children with AA to establish guidelines for screening...
September 27, 2017: JAMA Dermatology
https://www.readbyqxmd.com/read/28973107/nonhealing-leg-ulcer-in-a-middle-aged-indian-man
#9
Keshavamurthy Vinay, Dipankar De, Uma N Saikia
No abstract text is available yet for this article.
September 27, 2017: JAMA Dermatology
https://www.readbyqxmd.com/read/28973069/descriptive-error-in-the-text
#10
(no author information available yet)
No abstract text is available yet for this article.
September 27, 2017: JAMA Dermatology
https://www.readbyqxmd.com/read/28973061/association-between-the-use-of-a-physician-extender-and-dermatology-appointment-wait-times-in-ohio
#11
Frank Zurfley, Eliot N Mostow
No abstract text is available yet for this article.
September 27, 2017: JAMA Dermatology
https://www.readbyqxmd.com/read/28973060/evaluating-comorbidities-natural-history-and-predictors-of-early-resolution-in-a-cohort-of-children-with-chronic-urticaria
#12
Elena Netchiporouk, Denis Sasseville, Linda Moreau, Youssef Habel, Elham Rahme, Moshe Ben-Shoshan
Importance: Chronic urticaria (CU) affects 0.1% to 0.3% of children. Most cases have no identifiable trigger and are classified as chronic spontaneous urticaria (CSU). At least half of patients with CSU may have an autoimmune etiology that can be determined in vitro using the basophil activation test (BAT). While 30% to 55% of CU cases resolve spontaneously within 5 years in adults, the natural history and predictors of resolution in children are not known. Objective: To assess the comorbidities, natural history of CU, and its subtypes in children and identify predictors of resolution...
September 27, 2017: JAMA Dermatology
https://www.readbyqxmd.com/read/28973058/prior-authorizations-for-diagnostic-skin-biopsies-does-anyone-benefit
#13
Andrew T Rogers, Brittany Sutherland, Manisha J Loss
No abstract text is available yet for this article.
September 27, 2017: JAMA Dermatology
https://www.readbyqxmd.com/read/28975212/laser-induced-neocollagenesis-in-focal-dermal-hypoplasia-associated-with-goltz-syndrome-in-a-girl
#14
Andrew C Krakowski, David M Ozog, David Ginsberg, Carol Cheng, Marsha L Chaffins
Importance: Current models of Goltz syndrome cannot estimate the overall neocollagenesis and marked shift in collagen types after ablative fractional laser resurfacing (AFR) within treated areas of focal dermal hypoplasia (FDH). Objectives: To clinically improve FDH by using AFR to characterize the specific ratio of collagen types associated with observed clinical changes. Design, Setting, and Participants: This case report of a girl with Goltz syndrome used extensive laboratory evaluation and multiple observers blinded to the patient's clinical status...
September 20, 2017: JAMA Dermatology
https://www.readbyqxmd.com/read/28975210/the-treatment-of-actinic-keratoses-the-rule-rather-than-the-exception-reply
#15
Joslyn S Kirby
No abstract text is available yet for this article.
September 20, 2017: JAMA Dermatology
https://www.readbyqxmd.com/read/28975200/the-treatment-of-actinic-keratoses-the-rule-rather-than-the-exception
#16
Bobbak Mansouri, Chad D Housewright
No abstract text is available yet for this article.
September 20, 2017: JAMA Dermatology
https://www.readbyqxmd.com/read/28914955/alcohol-related-mortality-in-patients-with-psoriasis-a-population-based-cohort-study
#17
Rosa Parisi, Roger T Webb, Matthew J Carr, Kieran J Moriarty, C Elise Kleyn, Christopher E M Griffiths, Darren M Ashcroft
Importance: People diagnosed with psoriasis have an increased risk of premature mortality, but the underlying reasons for this mortality gap are unclear. Objective: To investigate whether patients with psoriasis have an elevated risk of alcohol-related mortality. Design, Setting, and Participants: An incident cohort of patients with psoriasis aged 18 years and older was delineated for 1998 through 2014 using the Clinical Practice Research Datalink (CPRD) and linked to Hospital Episode Statistics (HES) and Office for National Statistics (ONS) mortality records...
September 15, 2017: JAMA Dermatology
https://www.readbyqxmd.com/read/28903160/safety-of-systemic-agents-for-the-treatment-of-pediatric-psoriasis
#18
Inge M G J Bronckers, Marieke M B Seyger, Dennis P West, Irene Lara-Corrales, Megha Tollefson, Wynnis L Tom, Marcia Hogeling, Leah Belazarian, Claus Zachariae, Emmanuel Mahé, Elaine Siegfried, Sandra Philipp, Zsuzsanna Szalai, Ruth Ann Vleugels, Kristen Holland, Ruth Murphy, Eulalia Baselga, Kelly Cordoro, Jo Lambert, Alex Alexopoulos, Ulrich Mrowietz, Wietske Kievit, Amy S Paller
Importance: Use of systemic therapies for moderate to severe psoriasis in children is increasing, but comparative data on their use and toxicities are limited. Objective: To assess patterns of use and relative risks of systemic agents for moderate to severe psoriasis in children. Design, Setting, and Participants: A retrospective review was conducted at 20 centers in North America and Europe, and included all consecutive children with moderate to severe psoriasis who used systemic medications or phototherapy for at least 3 months from December 1, 1990, to September 16, 2014...
September 13, 2017: JAMA Dermatology
https://www.readbyqxmd.com/read/28903138/improvement-of-genetic-testing-for-cutaneous-melanoma-in-countries-with-low-to-moderate-incidence-the-rule-of-2-vs-the-rule-of-3
#19
Juliette Delaunay, Ludovic Martin, Brigitte Bressac-de Paillerets, Gerard Duru, Olivier Ingster, Luc Thomas
Importance: Genetic testing for melanoma-prone mutation in France, a country with low to moderate incidence of melanoma, is proposed in cases with 2 invasive cutaneous melanomas and/or related cancers in the same patient, or in first- or second-degree relatives (rule of 2). In preclinical studies, these rules led to disclosure of mutation(s) in more than 10% of these families, the threshold widely accepted to justify genetic testing for cancers. Objective: To reconsider these criteria in a general population testing of patients...
September 13, 2017: JAMA Dermatology
https://www.readbyqxmd.com/read/28903134/task-shifting-in-dermatology-a-call-to-action
#20
Danielle N Brown, Sinéad M Langan, Esther E Freeman
Clinical Question: Can task shifting be used to improve the delivery of dermatologic care in resource-poor settings worldwide? Bottom Line: Task shifting is a means of redistributing available resources, whereby highly trained individuals train an available workforce to provide necessary care in low-resource settings. Limited evidence exists for task shifting in dermatology; however, studies from psychiatry demonstrate its efficacy. In the field of dermatology there is a need for high-quality evidence including randomized clinical trials to validate the implementation of task shifting in low-resource settings globally...
September 13, 2017: JAMA Dermatology
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