Solange M Saxby, Farnoosh Shemirani, Landon J Crippes, Mary A Ehlinger, Lisa Brooks, Babita Bisht, Tyler J Titcomb, Linda M Rubenstein, Patrick Ten Eyck, Karin F Hoth, Christine Gill, John Kamholz, Linda G Snetselaar, Terry L Wahls
BACKGROUND: Interventions involving diet, physical activity, and breathing exercises are shown to be beneficial in managing both fatigue and quality of life (QoL) related to MS; however, the impact of such interventions among people newly diagnosed with clinically isolated syndrome (CIS) or relapsing-remitting multiple sclerosis (RRMS) who decline disease-modifying therapies (DMTs) is unknown. METHODS: A 12-month prospective quasi-experimental non-inferiority trial recruited people newly diagnosed with CIS or RRMS who voluntarily declined DMTs (health behavior group; HB, n = 29) or followed standard of care (SOC, n = 15)...
2024: Degenerative Neurological and Neuromuscular Disease