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Advanced Biomedical Research

Alireza Merrikhi, Elahe Ziaei, Armindokht Shahsanai, Roya Kelishadi, Asieh Maghami-Mehr
Background: This study aimed to evaluate the impact of Vitamin D supplementation on prevention of recurrent urinary tract infections (UTIs) in the pediatrics. Materials and Methods: This randomized, triple-blind, placebo-controlled clinical trial was conducted in 2014 among 68 children and adolescents with recurrent UTI. They were randomly assigned to two groups, receiving either Vitamin D (1000 IU/daily) or placebo for 6 months. The serum concentration of Vitamin D before and after the study and the frequency of UTI during the study were recorded...
2018: Advanced Biomedical Research
Wafa Khan, Dominic Augustine, Roopa S Rao, Samudrala Venkatesiah Sowmya, Vanishri C Haragannavar, Shwetha Nambiar
Background: Ameloblastic carcinoma (ACA) is a malignant neoplasm with overlapping histopathological features of benign aggressive solid multicystic ameloblastoma (SMA). This often leads to misdiagnosis with direct implication on the management protocol. The need of the hour is to adopt reliable tissue biomarkers to differentiate these lesions accurately that will help to implement an appropriate treatment modality. Few studies to differentiate ACA and SMA in literature with a limitation of a single marker and lack of availability of cases have prompted us to undertake this study...
2018: Advanced Biomedical Research
Victoria Omranifard, Mohammad Javad Tarrahi, Shima Sharifi, Mojgan Karahmadi
Background: This study aimed to evaluate the efficacy of memantine in the acute treatment of geriatric with bipolar disorder (BD) hospitalized for mania. Materials and Methods: This study conducted on 70 patients older than 60 years with BD in the acute phase of mania. Oral sodium valproate was prescribed in both groups. The intervention group received memantine tablet and the placebo group received a placebo tablet based on a same procedure. Severity of mania, cognitive changes, and quality of life (QoL) were assessed and recorded 4 and 8 weeks after the beginning of the study...
2018: Advanced Biomedical Research
Soroor Arman, Hajar Salimi, Mohammad Reza Maracy
Background: Bipolar disorders (BD) in parents can have different effects on children and perhaps as a reason of the incidence of various psychiatric disorders in them and they may show a particular parenting style due to features of their disease. Given a crucial role of parenting style in upbringing children, this study aimed to evaluate different styles of parenting and its relationship with psychiatric disorders in children of parents with bipolar disorder (PBD) compared with controls...
2018: Advanced Biomedical Research
Azadeh Bahadoori, Amir Shafa, Taha Ayoub
Background: This study aimed to evaluate and compare the therapeutic effects of ephedrine and lidocaine in treatment of intraoperative hiccups in gynecologic surgery under sedation. Materials and Methods: This randomized clinical trial in Isfahan was done on fifty female patients referring to Shahid Beheshti Hospital who needed to have sedation for medical interventions and they afflicted hiccups during surgery or sedation. Patients divided into two groups of 25 randomly assigned to one of the two groups of ephedrine or lidocaine...
2018: Advanced Biomedical Research
Fariba Iraji, Masoom Shahbazi, Bahareh Abtahi-Naeini, Ali Asilian, Zabihollah Shahmoradi, Anis Bostakian, Parvin Rajabi, Samira Kazemipour
Branchio-oculo-facial syndrome (BOFS), a rare, multiple-malformation congenital disorder, is characterized by facial anomalies, including associated cutaneous and ocular abnormalities. We report a new case of BOFS in an 11-year-old male child with bilateral cervical erythematous scaly linear plaque associated with scar formation and erosion. Although BOFS is very rare, physicians, especially dermatologists, should be aware of the cutaneous and histopathological features of BOFS due to impacts of the associated anomalies...
2018: Advanced Biomedical Research
Ali Tabrizi, Mohammad Javad Shariyate
Background: Meniscus plays an important role in weight-bearing and energy absorption. Moreover, its function is optimal to maintain joint stability and congruous. Treatments for meniscus damage or meniscus tear include open or arthroscopic repair and meniscectomy. One of the most important factors that influence patients' recovery outcome is restoration technique. The purpose of this study was to compare the strength of recently new method of meniscus repair, submeniscal horizontal sutures, and single vertical loop suturing techniques in meniscus repair...
2018: Advanced Biomedical Research
Jahangir Noori, Mohammadreza Sharifi, Shaghayegh Haghjooy Javanmard
Background: Epithelial-mesenchymal transition (EMT) is actively involved in tumor invasion. The main hallmark of EMT is downregulation of the adherens junction protein E-cadherin due to transcriptional repression. Candidate E-cadherin transcription repressors are members of ZEB family, ZEB2 belong to the ZEB family transcription factor that is pivotal for embryonic development and tumor progression. ZEB2 (zinc finger E-box binding homeobox 2) is most widely known as an inducer of EMT...
2018: Advanced Biomedical Research
Mahdi Vanaie, Majid Valiyan Boroujeni, Hamed Motavallipour Abarghuie, Ali Asghar Pourshanazari, Hossein Rezazadeh
Background: Sneezing transiently elevates cerebral blood flow. We speculated that induced sneezing, following embolism would restore arterial flow, thereby diminishing infarct volume and improving neurological deficits. Materials and Methods: Male rats were subjected to middle cerebral artery occlusion (MCAO) using prepared clots (embolization) and randomized into four equal groups as follows: (1) pre-MCAO-induced sneezing (PRMIS), (2) post-MCAO-induced sneezing (POMIS), and (3) pre- and POMIS (PRPOMIS) and the control group (eight rats per group)...
2018: Advanced Biomedical Research
Mohammad Reza Pourreza, Hannane Mohammadi, Ladan Sadeghian, Samira Asgharzadeh, Mohammadreza Sehhati, Mohammad Amin Tabatabaiefar
Background: Hearing loss (HL) is a highly prevalent heterogeneous deficiency of sensory-neural system with involvement of several dozen genes. Whole-exome sequencing (WES) is capable of discovering known and novel genes involved with HL. Materials and Methods: Two pedigrees with HL background from Khuzestan province of Iran were selected. Polymerase chain reaction-sequencing of GJB2 and homozygosity mapping of 16 DFNB loci were performed. One patient of the first and two affected individuals from the second pedigree were subjected to WES...
2018: Advanced Biomedical Research
Leili Adinehmehr, Sohrab Salimi, Mohammad Azad Majedi, Azadeh Alizadeh, Shahryar Sane
Background: Heat loss and core-to-peripheral redistribution of body heat occur in patients undergoing neuraxial anesthesia resulted to decrease of core temperature and early reach of shivering threshold. Because shivering has deleterious metabolic and cardiovascular effects, it should ideally be prevented by pharmacologic or other means. Tizanidine is an alpha-2 agonist. We evaluated the usefulness of oral tizanidine (TI) and tramadol in preventing of shivering in patients undergoing spinal anesthesia for transurethral resection of the prostate (TURP)...
2018: Advanced Biomedical Research
Masoomeh Latifi, Nader Alishan Karami, Mozhdeh Beiraghdar, Fatemeh Maraki, Leili Allahbakhshian Farsani
Background: Women with breast cancer experience various challenges. Prescription of health information provides appropriate information at appropriate time to the appropriate person and plays a role in empowering self-care and improving health. The current research aims to evaluate the effect of health information prescription on self-care power of women with breast cancer. Materials and Methods: This semi-experimental quantitative study was done using pretest and posttest method in one group of 61 women with breast cancer selected from the Women's Cancer Center of Khatamolanbia Hospital using purposive sampling method...
2018: Advanced Biomedical Research
Parastoo Golshiri, Ziba Farajzadegan, Anita Tavakoli, Kamal Heidari
Background: Youth violence is an important public health challenge, and the literature on this problem in developing countries has been limited. The present study aims to determine the prevalence of violence its related risk factors in in a sample of students in Isfahan, Iran. Materials and Methods: In this cross-sectional study, 2800 middle and high school, aged 11-18 years in urban and rural areas selected in a multistage sampling procedure and were questioned using a self-administered questionnaire...
2018: Advanced Biomedical Research
Hajaralsadat Hosseini Dastgerdi, Maryam Radahmadi, Parham Reisi, Azadehalsadat Hosseini Dastgerdi
Background: Stress affects brain functions and induces psychological disorders. Previous studies have indicated different effects of crocin and exercise on the improvement of memory in some types of stress. The present study investigated the effect of crocin, exercise, and crocin-accompanied exercise on learning, memory, and memory consolidation in rats under chronic unpredictable stress (CUS). Materials and Methods: Male rats were randomly allocated to different groups: control, sham, stress, stress-exercise, stress-crocin, and stress-crocin-accompanied exercise groups...
2018: Advanced Biomedical Research
Mohadeseh Ghasemi, Ahmad Yaraghi, Ziba Farajzadegan, Ali Mohammad Sabzghabaee, Nastaran Eizadi-Mood
Background: There have been studies on the outcome of acute intoxication with antidepressants or antipsychotics. We performed outcome prediction analysis in acute poisoning patients with antidepressants/antipsychotics with or without combination with other drugs. Materials and Methods: A cross-sectional study was performed in Khorshid (PBUH) University Hospital affiliated with Isfahan University of Medical Sciences from March 2016 to May 2017. Patients with acute poisoning ingested antidepressants and antipsychotics with or without other drugs were included in the study...
2018: Advanced Biomedical Research
Zahra Sharifian, Marjan Mansourian, Masoud Rismanchian
Background: At workplaces, the workers exposed to several harmful agents such as physical, chemical, and biological pollutant that cause occupational diseases. There are a lot of jobs that not allow a certain pattern of exposure to this agent. In this article, we introduce a technology named radio-frequency identification (RFID) to estimate the exposure time of workers to harmful agent. Materials and Methods: This applied study was carried out experimentally in an industry in Isfahan province, Iran...
2018: Advanced Biomedical Research
Behzad Nazemroaya, Mohammad Azad Majedi, Hamidreza Shetabi, Sanaz Salmani
Background: Breast lumpectomy is an integral part of the treatment of mammary masses in women. This study was conducted to evaluate and compare two-drug combinations of propofol-ketamine (PK) (ketofol) and propofol-fentanyl (PF) (fenofol) on quality of sedation and analgesia in lumpectomy. Materials and Methods: This was a randomized, double-blind, clinical trial performed on 64 patients aged 15-70 years with breast cancer lumpectomy referred to Isfahan's Seyed Al-Shohada Hospital...
2018: Advanced Biomedical Research
Fakhrolmolouk Yassaee, Saeedeh Salimi, Samaneh Etemadi, Minoo Yaghmaei
Background: Preeclampsia (PE) is one of the main causes of maternal and perinatal mortality and morbidity. Evidence shows that oxidative stress plays an important role in the pathophysiology of the PE. As catalase is a key enzyme in antioxidant enzymatic defense which protects cell from oxidative damage, in this study, we aimed to investigate the relationship between CAT-21A/T (rs7943316) polymorphism and PE susceptibility. Materials and Methods: This case-control study was conducted on 155 PE women and 159 normotensive pregnant women...
2018: Advanced Biomedical Research
Behzad Zolfaghari, Abbas Jafarian, Moein Rezaei
Background: Seidlitzia rosmarinus which is commonly called "Oshnan" or "Eshnan" in Persian belongs to Chenopodiaceae family. Conventionally, it is believed that this plant is toxic. This study was aimed to evaluate the cytotoxic effect of S. rosmarinus against HeLa and HepG2 cell lines. Materials and Methods: S. rosmarinus was collected from the desert near Yazd, Iran. Hexane, chloroform, chloroform/methanol (9:1), and butanol extracts of aerial parts of S...
2018: Advanced Biomedical Research
Mojgan Karahmadi, Mohammad Javad Tarrahi, Samaneh Sadat Vatankhah Ardestani, Victoria Omranifard, Behdad Farzaneh
Background: Autism spectrum disorder (ASD) is a neurodevelopmental disorder with a recent increase in prevalence. A timely appropriate treatment for the disorder may play a crucial role in improvements in behaviors, interactions, and communications in an individual's life. It appears that evaluation of therapeutic approaches to the patients is essential and of importance. Thus, the aim of this study was to evaluate the efficacy of memantine as adjunct therapy in children with ASD. Materials and Methods: This randomized single-blind clinical trial included 60 children with ASD aged <14...
2018: Advanced Biomedical Research
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