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Advanced Biomedical Research

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https://www.readbyqxmd.com/read/28299308/malignant-transformation-of-an-intracranial-extradural-epidermoid-cyst-into-squamous-cell-carcinoma-presented-with-cerebrospinal-fluid-leakage
#1
Bahram Seif, Reza Pourkhalili, Ahmad Shekarchizadeh, Parvin Mahzouni
We report a case of malignant transformation of an intracranial extradural epidermoid cyst into squamous cell carcinoma (SCC), that presented with cerebrospinal fluid (CSF) leakage at the time of recurrence. Intracranial epidermoid cysts are histologically benign and slow-growing neoplasms. They are congenital lesions that develop from ectodermal remnants during neuroembryogenesis. Malignant transformation of epidermoid cysts into SCC is very rare. Various clinical presentations of these tumors after malignant transformation are mentioned in the literature...
2017: Advanced Biomedical Research
https://www.readbyqxmd.com/read/28299307/identification-of-appropriate-housekeeping-genes-for-gene-expression-analysis-in-long-term-hypoxia-treated-kidney-cells
#2
Shiva Moein, Shaghayegh Haghjooy Javanmard, Maryam Abedi, Mohammad Hosein Izadpanahi, Yousof Gheisari
BACKGROUND: Selection of stably expressing housekeeping genes (HKGs) is a crucial step in gene expression analysis. However, there are no universal HKGs for all experiments, and they should be determined by each biologic condition. The aim of this study was to detect appropriate HKGs for kidney cells cultured in long-term hypoxia. MATERIALS AND METHODS: Based on a screening step using a microarray data available from gene expression omnibus database, a set of candidate HKGs were chosen to be assessed in human kidney cells cultured in hypoxic or normoxic conditions for about 2 weeks in a time course manner...
2017: Advanced Biomedical Research
https://www.readbyqxmd.com/read/28299306/expression-of-estrogen-receptor-alpha-in-malignant-melanoma
#3
Parvin Rajabi, Marzieh Bagheri, Mohsen Hani
BACKGROUND: Features of malignant melanoma (MM) vary in the different geographic regions of the world. This may be attributable to environmental, ethnic, and genetic factors. The aim of this study was to determine the expression of estrogen receptor alpha (ER-α) in MM in Isfahan, Iran. MATERIALS AND METHODS: This study was planned as a descriptive, analytical, cross-sectional investigation. During this study, paraffin-embedded tissue blocks of patients with a histopathologic diagnosis of MM was studied for ER-α using immunohistochemistry (IHC)...
2017: Advanced Biomedical Research
https://www.readbyqxmd.com/read/28299305/the-role-of-inflammatory-processes-in-occurrence-of-left-ventricular-failure-in-patients-with-chronic-kidney-disease
#4
Hassan Shemirani, Sara Tavakol, Abdolamir Atapoor, Jafar Golshahi
BACKGROUND: Recently, the relationship between increased level of inflammatory mediators and occurrence of left ventricular failure in patients with kidney disease has been suggested. The present study attempted to assess relationship between inflammatory mediators and occurrence of left ventricular failure in patients with chronic kidney disease. MATERIALS AND METHODS: This cross-sectional study was performed at Noor and Hazrat Aliasghar hospital in Isfahan between September 2012 to September 2013 on patients aged >19 years that referred for following their chronic kidney disease...
2017: Advanced Biomedical Research
https://www.readbyqxmd.com/read/28299304/effects-of-phlebotomy-on-liver-enzymes-and-histology-of-patients-with-nonalcoholic-fatty-liver-disease
#5
Mahsa Khodadoostan, Maryam Zamanidoost, Ahmad Shavakhi, Hosein Sanei, Masood Shahbazi, Mehdi Ahmadian
BACKGROUND: Nonalcoholic fatty liver disease (NAFLD), defined as excessive liver fat deposition and one of end-stage liver disease causes. Increased ferritin levels are associated with insulin resistance and a higher hepatic iron and fat content. Hyperferritinemia has been associated with severity of liver damage in NAFLD. The study aimed to evaluate the effects of phlebotomy on liver enzymes and histology in such patients. MATERIALS AND METHODS: Thirty-two eligible patients who had NAFLD and after 6 months of lifestyle modification still had NAFLD, and whose ferritin serum was above 250 mg/dl, were enrolled in this clinical trial study...
2017: Advanced Biomedical Research
https://www.readbyqxmd.com/read/28299303/the-efficacy-of-augment-of-d-cycloserine-and-cognitive-behavioral-therapy-on-adolescent-with-one-type-of-anxiety-disorders-a-double-blind-randomized-controlled-trial
#6
Soroor Arman, Ali Soheilimehr, Mohammad Reza Maracy
BACKGROUND: This study was designed to investigating the effect of combining D-cycloserine (DCS) and cognitive-behavioral therapy (CBT) on adolescent with at least one type of anxiety disorders. MATERIALS AND METHODS: The present study was conducted as a double-blind randomized controlled trial on 36 adolescent with anxiety disorders. Patients were assessed in two groups. In addition to 4 sessions of weekly CBT in both groups; case group, received a 50-mg DCS capsules, control group, received Placebo daily for a month...
2017: Advanced Biomedical Research
https://www.readbyqxmd.com/read/28299302/cornea-collagen-cross-linking-for-keratoconus-a-comparison-between-accelerated-and-conventional-methods
#7
Hasan Razmjoo, Alireza Peyman, Ali Rahimi, Hoda Jafari Modrek
BACKGROUND: Keratoconus is a progressive degenerative disorder of the cornea in which structural changes in the cornea cause it to become thin and conical in shape. Recently, collagen cross-linking (CXL) has been introduced as an effective intervention in management of progressive keratoconus. Accelerated CXL is a new protocol of this procedure which reduces corneal ultraviolet irradiation exposure time to 5 min. This study aimed to compare visual acuity, keratometry and topographic criteria of keratoconic eyes after conventional and accelerated CXL with a six-month follow-up...
2017: Advanced Biomedical Research
https://www.readbyqxmd.com/read/28299301/solution-of-azelaic-acid-20-resorcinol-10-and-phytic-acid-6-versus-glycolic-acid-50-peeling-agent-in-the-treatment-of-female-patients-with-facial-melasma
#8
Gita Faghihi, Azam Taheri, Zabihollah Shahmoradi, Mohammad Ali Nilforoushzadeh
BACKGROUND: Melasma, a common acquired disorder of hyperpigmentation, especially in women, is often resistant to therapy. This study was aimed to evaluate the efficacy and safety of azelaic acid, resorcinol and phytic acid solution in chemical peeling of melasma in comparison to 50% glycolic acid. MATERIALS AND METHODS: This clinical trial was performed, on 42 female patients with bilateral melasma. Severity of melasma was assessed by melasma area and severity index (MASI)...
2017: Advanced Biomedical Research
https://www.readbyqxmd.com/read/28217653/corticosteroid-and-azithromycin-in-idiopathic-granulomatous-mastitis
#9
Marzieh Salehi, Maryam Salehi, Nader Kalbasi, Atousa Hakamifard, Hassan Salehi, Mohammad Mahdi Salehi, Jalil Sharifian
BACKGROUND: Mastitis is an inflammatory disorder in breast tissues due to bacterial factors, mycobacterial infections or autoimmune diseases. Idiopathic granulomatous mastitis (IGM) is a form of mastitis which may be affected by systematic diseases such as sarcoidosis, and infectious causes such as mycobacterium and fungus. This study evaluates the efficacy of medical therapy with a combination of corticosteroid and Azithromycin in patients with IGM. MATERIALS AND METHODS: This study is a clinical trial research carried out in Alzahra Hospital (Isfahan, Iran) in 2013 on granulomatous mastitis patients...
2017: Advanced Biomedical Research
https://www.readbyqxmd.com/read/28217652/is-there-any-correlation-between-magnetic-resonance-imaging-features-of-breast-lesions-of-birads-category-4-with-histopathologic-results
#10
Maryam Farghadani, Ghazale Jamalipoor Soofi, Amir Hossein Sarrami
BACKGROUND: To evaluate the correlation of magnetic resonance imaging (MRI) features of breast lesions of Breast Imaging Reporting and Database System (BI-RADS) category 4 with histopathologic results. MATERIALS AND METHODS: In a prospective study between December 2013 and April 2015, patients with suspicious mammographic and/or ultrasound findings referred for Breast MRI were evaluated. Patients with lesions of BI-RADS category 4 were enrolled with a written informed consent...
2017: Advanced Biomedical Research
https://www.readbyqxmd.com/read/28217651/differential-immune-reactivity-pattern-of-sw48-and-sw1116-colorectal-cancer-cell-lines-with-colorectal-cancer-patients-sera
#11
Ghasem Ghalamfarsa, Seyyed Vahid Hosseini, Maryam Hamidinia, Abbas Ghaderi, Mahmoud Mahmoudi, Zahra Mojtahedi
BACKGROUND: Colorectal cancer (CRC) is one of the most commonly diagnosed cancers worldwide. It is also known as the second leading cause of deaths as the early stage detection is not yet available by current methods. So identification of biomarkers can also be functional in early diagnosis and prognosis. MATERIALS AND METHODS: We examined sera from 60 CRC patients of different stages as a source of auto-antibody as well as two human CRC cell lines with different invasive capacities (SW48 and SW1116) as the source of antigens...
2017: Advanced Biomedical Research
https://www.readbyqxmd.com/read/28217650/comparing-the-effect-of-dressing-versus-no-dressing-on-exit-site-infection-and-peritonitis-in-chronic-ambulatory-peritoneal-dialysis-patients
#12
Shahram Taheri, Mahdieh Ahmadnia, Mojgan Mortazavi, Shirin Karimi, Homa Reihani, Shiva Seirafian
BACHGROUND: Peritonitis and exit site (ES) infection are two main complications of peritoneal dialysis. There are some controversies regard to preventive strategies for ES care. In this study we compared peritonitis and ES infection rates in patients with and without dressing. MATERIALS AND METHODS: This historical cohort study carried out on 72 patients under continuous ambulatory peritoneal dialysis treatment, 54 with dressing versus 18 patients without dressing, followed from October 1, 2010 to March 31, 2011 for peritonitis and ES infection...
2017: Advanced Biomedical Research
https://www.readbyqxmd.com/read/28217649/effects-of-the-schema-therapy-and-mindfulness-on-the-maladaptive-schemas-hold-by-the-psoriasis-patients-with-the-psychopathology-symptoms
#13
Parvin Jamali Gojani, Mohsen Masjedi, Shahnaz Khaleghipour, Ehsan Behzadi
BACKGROUND: This study aimed to compare the effects of the schema along with mindfulness-based therapies in the psoriasis patients. MATERIALS AND METHODS: This semi-experimental study with post- and pre-tests was conducted on the psoriasis patients in the Dermatology Clinic of the Isfahan Alzahra Hospital, Iran using the convenience sampling in 2014. The patients had a low general health score. The experimental groups included two treatment groups of schema-based (n = 8) and mindfulness (n = 8)...
2017: Advanced Biomedical Research
https://www.readbyqxmd.com/read/28217648/psychological-and-familial-factors-of-depression-in-relation-to-adolescent-smoking-behavior
#14
Hamidreza Roohafza, Razieh Omidi, Tahereh Alinia, Kamal Heidari, Marziyeh Farshad, Hossein Davari, Zahra Abtin, Ezat Shahriari, Mahshid Taslimi, Masoumeh Sadeghi
BACKGROUND: Several common factors have been identified for smoking and depression. The The present study explores the relation of psychological and familial factors with depression, by student smoking behavior. MATERIALS AND METHODS: A total of 5500 middle- and high-school students were selected in Isfahan province in 2010. A self-administered questionnaire collected data on background characteristics, smoking status, depression, and risk factors. Univariate analysis multiple logistic regressions were conducted to compare between depressed and nondepressed people by adolescent smoking status...
2017: Advanced Biomedical Research
https://www.readbyqxmd.com/read/28217647/wound-healing-effect-of-arnebia-euchroma-gel-on-excisional-wounds-in-rats
#15
Maryam Mohsenikia, Shahrzad Khakpour, Zahra Azizian, Soheil Ashkani-Esfahani, Seyyede Tahereh Razavipour, Pooya Toghiani
BACKGROUND: Wound healing is a complex process leading to regeneration of damaged skin tissue. Arnebia euchroma (AE) have many effective activities such as anti-inflammatory, antimicrobial, antioxidative, and anti-tumoral effects. The extract of AE has positive effects on burn wounds. This study is designed to investigate the healing effects of AE on excisional wounds in rats. MATERIALS AND METHODS: Thirty six rats with the age of 8 weeks divided into three groups...
2017: Advanced Biomedical Research
https://www.readbyqxmd.com/read/28217646/nocardia-isolation-of-soil
#16
Mehdi Fatahi Bafghi, Seyyed Saeed Eshraghi
No abstract text is available yet for this article.
2017: Advanced Biomedical Research
https://www.readbyqxmd.com/read/28217645/comparison-of-short-head-up-tilt-test-with-conventional-protocol-after-omission-of-nonmedicated-phase-in-children-and-young-adults
#17
Bahar Dehghan, Mohammad Reza Sabri
BACKGROUND: Syncope is an important and common clinical condition, and the neurally mediated syncope is the most frequent type of syncope. Tilt testing is considered as a first-line diagnostic test. MATERIALS AND METHODS: We conducted the conventional and modified tilt test on 200 subjects in the age range of 5-20 years. In conventional protocol, the patient was tilted for up to 15 min without medication. If syncope did not develop, the patient received 0.1 mg/kg sublingual isosorbide dinitrate...
2016: Advanced Biomedical Research
https://www.readbyqxmd.com/read/28217644/do-serum-prolactin-levels-correlate-with-antibodies-against-desmoglein-in-pemphigus-vulgaris
#18
Fariba Iraji, Nabet Tajmirriahi, Iman Momeni, Kioumars Jamshidi, Fazlollah Hashemzehi, Amir Hossein Siadat, Alireza Asemi Esfahani
BACKGROUND: Pemphigus vulgaris is a chronic inflammatory disease of skin, the etiology of which is not completely known. Despite the latter, anti-desmoglein antibodies play a proven role in the pathogenesis. Recent studies showed an etiologic effect for prolactin in the pemphigus vulgaris. This study aimed to quantify the correlation between serum prolactin levels and anti-desmoglein antibodies in patients with pemphigus vulgaris. MATERIALS AND METHODS: Prolactin and antibodies against desmoglein 1 and 3 measured with ELISA in 14 new subjects of pemphigus vulgaris...
2016: Advanced Biomedical Research
https://www.readbyqxmd.com/read/28217643/a-case-of-the-long-time-presence-of-a-large-foreign-body-in-esophagus-without-complication
#19
Gholamreza Mohajeri, Shiva Fakhari, Zahra Ghaffarzadeh, Mohammadreza Piri-Ardakani
Dentures are common accidentally ingested foreign bodies (FBs), especially in the aged population. It is usual for a FB to be swallowed in adults and lodge in the esophagus; however, it is unusual for a denture to remain in esophagus for a period of 9 months without any complication. We present, a 57-year-old deaf mute man swallowed his denture with the chief complaint of dysphagia and odynophagia only after 9 months. Although multiple attempts for removing the denture by rigid esophagoscopy were done, it entered the stomach, so gastrotomy was performed and the patient recovered uneventfully...
2016: Advanced Biomedical Research
https://www.readbyqxmd.com/read/28217642/immediate-outcomes-of-eptifibatide-therapy-during-intracoronary-stent-implantation
#20
Hooman Shariati, Hamid Sanei, Ali Pourmoghadas, Leila Salehizadeh, Afshin Amirpour
BACKGROUND: The objective of the present study was to assess the major immediate outcomes of eptifibatide therapy during intracoronary stent implantation. MATERIALS AND METHODS: In an interventional study, patients undergoing percutaneous coronary intervention (PCI) were randomized into either the eptifibatide (n = 100) or the control (n = 107) group. In each group, demographic and clinical characteristics such as cardiac death, stent thrombosis (ST), myocardial infarction (MI), rates of target lesion and vessel revascularization, cerebral vascular accident (CVA), and emergency coronary artery bypass grafting (CABG) were recorded...
2016: Advanced Biomedical Research
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