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Advanced Biomedical Research

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https://www.readbyqxmd.com/read/28028530/acid-base-and-hemodynamic-status-of-patients-with-intraoperative-hemorrhage-using-two-solution-types-crystalloid-ringer-lactate-and-1-3-sodium-bicarbonate-in-half-normal-saline-solution
#1
Sayed Jalal Hashemi, Sayed Morteza Heidari, Ahmad Yaraghi, Reza Seirafi
BACKGROUND: Intraoperative hemorrhage is one of the problems during surgery and, if it happens in a high volume without an immediate action to control, it can be fatal. Nowadays, various injectable solutions are used. The aim of this study was to compare the acid-base and hemodynamic status of the patient using two solutions, Ringer lactate and 1.3% sodium bicarbonate, in half saline solution. MATERIALS AND METHODS: This clinical trial was performed at the Al-Zahra Hospital in 2013 on 66 patients who were randomly selected and put in two studied groups at the onset of hemorrhage...
2016: Advanced Biomedical Research
https://www.readbyqxmd.com/read/28028529/purification-of-lactoperoxidase-from-bovine-whey-and-investigation-of-kinetic-parameters
#2
Fatemeh Borzouee, Mohammad Reza Mofid, Jaleh Varshosaz, Seyed Ziyae Aldin Samsam Shariat
BACKGROUND: Lactoperoxidase (LPO) is related to mammalian peroxidase family which contains a wide spectrum of biological activities. Despite the wide studies on the LPO, there is little study has been performed to simplify and shorten the procedure of enzyme purification. The aim of this project was to purify the enzyme through a simple method, and investigating enzyme kinetic parameters. MATERIALS AND METHODS: LPO was purified from bovine whey through modified method of Yoshida (1990) using two steps of ammonium sulfate precipitation and ion-exchange chromatography...
2016: Advanced Biomedical Research
https://www.readbyqxmd.com/read/28028528/the-comparison-of-treatments-with-and-without-azithromycin-in-irritable-bowel-syndrome-with-diarrhea-predominant-in-gastrointestinal-clinic-of-al-zahra-hospital-isfahan-iran
#3
Mohamadreza Yazdani, Amirhossein Aramesh, Rahmatollah Rafiei, Hamed Daghaghzadeh, Peyman Adibi
BACKGROUND: Irritable bowel syndrome (IBS) is a common gastrointestinal disorder. Recent studies suggest the importance of gut flora in the pathophysiology of it. Therefore, antibiotics have demonstrated a substantial benefit to reduce gut flora. Having few side effects, and applying one-dose per day, we studied the effect of azithromycin to treat IBS. MATERIALS AND METHODS: One hundred and twenty-six patients enrolled a randomized, double-blind, placebo-controlled study...
2016: Advanced Biomedical Research
https://www.readbyqxmd.com/read/28028527/from-conventional-therapy-toward-microrna-based-therapy-in-acute-promyelocytic-leukemia
#4
REVIEW
Naeim Ehtesham, Mohammadreza Sharifi
Acute promyelocytic leukemia (APL) is a hematopoietic malignancy that is known with its special cytogenetic feature. Several studies have surveyed expression signature of microRNAs (miRNAs) in APL patients, especially patients who are treated with conventional therapy of this disease. Using miRNAs as diagnostic or prognostic biomarkers in various cancers has been widely studied. Currently, most studies are focusing on exploiting miRNAs as therapeutic tools, and promising progress has been achieved in this field...
2016: Advanced Biomedical Research
https://www.readbyqxmd.com/read/28028526/investigation-of-the-relationship-between-idiopathic-microscopic-hematuria-in-the-first-and-second-trimesters-and-major-adverse-outcomes-of-pregnancy
#5
Azar Danesh Shahraki, Mahboobeh Esteki Bardeh, Mohammad Reza Najarzadegan
BACKGROUND: The aim of this study was to investigate the relationship between idiopathic microscopic hematuria (in the first and second trimesters) and major adverse outcomes of pregnancy. MATERIALS AND METHODS: Urinalysis was done for 700 pregnant women before 24 weeks of pregnancy. Those who had 3-5 red blood cells per milliliter in urinalysis were considered positive urinalysis. Then, all individuals were examined for blood pressure and other alarm signs of pregnancy complications in each visit...
2016: Advanced Biomedical Research
https://www.readbyqxmd.com/read/28028525/is-there-any-relationship-between-different-phenotypes-of-metabolic-syndrome-and-cardiovascular-mortality-rate
#6
Alireza Khosravi, Sareh Ahmadzadeh, Mojgan Gharipour, Jafar Golshahi, Masoumeh Sadeghi, Mahnaz Jozan, Nizal Sarrafzadegan
BACKGROUND: This study aimed to focus on different phenotypes of metabolic syndrome (MetS) and their impact on the cardiovascular disease (CVD) events among a sample of the Iranian population. MATERIALS AND METHODS: The Isfahan cohort study is a population-based, on-going longitudinal study of adults aged 35 years old or more, living in urban and rural areas of three counties in central Iran namely Isfahan, Najafabad and Arak. Participants were selected by multistage random sampling and were recruited to reflect the age, sex and urban/rural distribution of the community...
2016: Advanced Biomedical Research
https://www.readbyqxmd.com/read/28028524/effect-of-phone-call-versus-face-to-face-follow-up-on-recurrent-suicide-attempts-prevention-in-individuals-with-a-history-of-multiple-suicide-attempts
#7
Seyed Ghafur Mousavi, Mohsen Amini, Behzad Mahaki, Reza Bagherian-Sararoudi
BACKGROUND: To evaluate the efficacy of different ways of communications on prevention of suicidal reattempt, we compared the efficacy of phone call versus face-to-face follow-up in patients with previous attempt. MATERIALS AND METHODS: In a randomized controlled clinical trial, 55 suicide reattempters who were admitted to the poisoning emergency were divided into phone call (29 patients) and face-to-face (26 patients) groups randomly. They were followed at 8 occasions: 2(nd) and 4(th) weeks, and the 2(nd), 3(rd), 4(th), 5(th), 6(th), and 8(th) months...
2016: Advanced Biomedical Research
https://www.readbyqxmd.com/read/28028523/anxiety-depression-and-distress-among-irritable-bowel-syndrome-and-their-subtypes-an-epidemiological-population-based-study
#8
Hamidreza Roohafza, Ehsan Zare Bidaki, Ammar Hasanzadeh-Keshteli, Hamed Daghaghzade, Hamid Afshar, Peyman Adibi
BACKGROUND: Psychiatric disorders are common in irritable bowel syndrome (IBS). We conducted this study to investigate the relationship of IBS and their subtypes with some of psychological factors. MATERIALS AND METHODS: A cross-sectional study was performed among 4763 staff of Isfahan University of Medical Sciences in 2011. Modified ROME III questionnaire and Talley Bowel Disease Questionnaire were used to evaluate IBS symptoms. Hospital Anxiety and Depression Scale and 12-item General Health Questionnaire were utilized to assess anxiety, depression and psychological distress...
2016: Advanced Biomedical Research
https://www.readbyqxmd.com/read/28028522/preparation-and-evaluation-of-a-hair-wax-containing-propolis-and-eruca-sativa-seed-oil-for-hair-growth
#9
Mohammad-Ali Shatalebi, Leila Safaeian, Azar Baradaran, Mozhde Alamdarian
BACKGROUND: Hair growth as a key consumer objective has important role in the hair care products researches. This study was aimed to investigate the effect of a hair wax containing propolis, a resinous mixture produced by honeybees in Eruca sativa seed oil base on hair growth. MATERIALS AND METHODS: The hair wax was designed and formulated compared with marketed brand hair wax and evaluated for pharmaceutical parameters including pH, homogeneity, consistency, spread ability, in vitro drug release, and stability...
2016: Advanced Biomedical Research
https://www.readbyqxmd.com/read/28028521/beijing-strains-of-mycobacterium-tuberculosis-in-smear-positive-tuberculosis-patients-in-north-west-and-west-of-iran
#10
Leyla Sahebi, Khalil Ansarin, Sven Hoffner, Parviz Mohajeri, Abolghasem Mohammadi
BACKGROUND: Tuberculosis (TB) is the leading cause of morbidity and mortality among chronic infectious diseases. The goal of this cross-sectional study (2012-2014) was to examine the prevalence of Mycobacterium TB (MTB) Beijing strains in regions near the Iranian border and to identify any epidemiological links. MATERIALS AND METHODS: To this end, MTB isolates were harvested, from 64 HIV-negative, pulmonary smear-positive TB patients from the Iranian border provinces of East Azerbaijan (North-West), Kurdistan (West), and Kermanshah (West) (2012-2014)...
2016: Advanced Biomedical Research
https://www.readbyqxmd.com/read/28028520/evaluation-of-structural-and-mechanical-properties-of-electrospun-nano-micro-hybrid-of-poly-hydroxybutyrate-chitosan-silk-scaffold-for-cartilage-tissue-engineering
#11
Saeed Karbasi, Farnoosh Fekrat, Daryoush Semnani, Shahnaz Razavi, Elham Naghash Zargar
BACKGROUND: One of the new methods of scaffold fabrication is a nano-micro hybrid structure in which the properties of the scaffold are improved by introducing nanometer and micrometer structures. This method could be suitable for scaffold designing if some features improve. MATERIALS AND METHODS: In this study, electrospun nanofibers of 9% weight solution of poly (3-hydroxybutyrate) (P3HB) and a 15% weight of chitosan by trifluoroacetic acid were coated on both the surface of a silk knitted substrate in the optimum condition to improve the mechanical properties of scaffolds for cartilage tissue engineering application...
2016: Advanced Biomedical Research
https://www.readbyqxmd.com/read/28028519/beneficial-effects-of-platelet-rich-plasma-on-improvement-of-pain-severity-and-physical-disability-in-patients-with-plantar-fasciitis-a-randomized-trial
#12
Babak Vahdatpour, Lida Kianimehr, Ahmad Moradi, Shila Haghighat
BACKGROUND: The present study aimed to clinically examine the effects of platelet-rich plasma (PRP) on improvement of plantar fasciitis and its related manifestations. PATIENTS AND METHODS: This single-blind randomized controlled trial was performed on 32 consecutive patients with the final diagnosis of plantar fasciitis that were randomly assigned to the case group (that received PRP, n = 16) and the control group (that received corticosteroid as methylprednisolone 1 ml plus lidocaine 1 ml, n = 16)...
2016: Advanced Biomedical Research
https://www.readbyqxmd.com/read/28028518/study-of-the-effects-of-controlled-morphine-administration-for-treatment-of-anxiety-depression-and-cognition-impairment-in-morphine-addicted-rats
#13
Majid Motaghinejad, Sulail Fatima, Sanaz Banifazl, Mohammad Yasan Bangash, Morteza Karimian
BACKGROUND: Morphine dependency usually results in undesired outcomes such as anxiety, depression, and cognitive alterations. In this study, morphine was used to manage morphine dependence-induced anxiety, depression, and learning and memory disturbances. MATERIALS AND METHODS: Forty rats were divided equally into five groups. Group 1 received saline for 21 days. Groups 2-5 were dependent by increasing administration of morphine (15-45 mg/kg) for 7 days. For the next 14 days, morphine was administered as the following regimen: Group 2: once daily; 45 mg/kg (positive controls), Group 3: the same dose with an increasing interval (6 h longer than the previous intervals each time), Group 4: the same dose with an irregular intervals (12, 24, 36 h intervals interchangeably), and Group 5: decreasing doses once daily (every time 2...
2016: Advanced Biomedical Research
https://www.readbyqxmd.com/read/28028517/preparation-and-characterization-of-poly-hydroxy-butyrate-chitosan-blend-scaffolds-for-tissue-engineering-applications
#14
Saeed Karbasi, Saied Nouri Khorasani, Somayeh Ebrahimi, Shahla Khalili, Farnoosh Fekrat, Davoud Sadeghi
BACKGROUND: Poly (hydroxy butyrate) (PHB) is a biodegradable and biocompatible polymer with good mechanical properties. This polymer could be a promising material for scaffolds if some features improve. MATERIALS AND METHODS: In the present work, new PHB/chitosan blend scaffolds were prepared as a three-dimensional substrate in cartilage tissue engineering. Chitosan in different weight percent was added to PHB and solved in trifluoroacetic acid. Statistical Taguchi method was employed in the design of experiments...
2016: Advanced Biomedical Research
https://www.readbyqxmd.com/read/28028516/the-effect-of-head-covering-in-prevention-of-phototherapy-induced-hypocalcemia-in-icterus-newborns-with-gestational-age-less-than-35-weeks
#15
Behzad Barekatain, Zohrea Badiea, Neda Hoseini
BACKGROUND: Hypocalcemia is one of the complications of phototherapy resulted from influence of phototherapy in melatonin secretion reducing corticosterone and ultimately increasing bone uptake. In this study, effect of head covering in prevention of this common and serious complication is studied. MATERIALS AND METHODS: This prospective, randomized clinical trial study conducted on premature infants with gestational age <35 weeks with jaundice. Infants were divided into two groups (n = 43)...
2016: Advanced Biomedical Research
https://www.readbyqxmd.com/read/28028515/comparison-of-respiratory-and-hemodynamic-stability-in-patients-with-traumatic-brain-injury-ventilated-by-two-ventilator-modes-pressure-regulated-volume-control-versus-synchronized-intermittent-mechanical-ventilation
#16
Omid Aghadavoudi, Babak Alikiaii, Fariba Sadeghi
BACKGROUND: This study aimed to compare pressure regulated volume control (PRVC) and synchronized intermittent mechanical ventilation (SIMV) modes of ventilation according to respiratory and hemodynamic stability in patients with traumatic brain injury (TBI) admitted to Intensive Care Unit (ICU). MATERIALS AND METHODS: In a randomized, single-blinded, clinical trial study, 100 patients who hospitalized in ICU due to TBI were selected and randomly divided into two groups...
2016: Advanced Biomedical Research
https://www.readbyqxmd.com/read/28028514/the-effect-of-melatonin-on-endothelial-dysfunction-in-patient-undergoing-coronary-artery-bypass-grafting-surgery
#17
Shaghayegh Haghjooy Javanmard, Kiyan Heshmat-Ghahdarijani, Mohsen Mirmohammad-Sadeghi, Sayed Ali Sonbolestan, Amin Ziayi
BACKGROUND: In this study, we investigated the effect of melatonin administration on four markers of endothelial cell function including intercellular adhesion molecule (ICAM), vascular cell adhesion molecule (VCAM), C-reactive protein (CRP), and nitric oxide (NO) on patients with three vessels coronary disease. MATERIALS AND METHODS: This double-blind, randomized, controlled trial study was conducted on 39 patients (32 men and 7 women) with three vessels coronary disease...
2016: Advanced Biomedical Research
https://www.readbyqxmd.com/read/28028513/evaluation-of-endothelial-function-in-exogenous-subclinical-hyperthyroidism-and-the-effect-of-treatment
#18
Sayed Mohammad Hosseini, Elham Khosravi Bakhtyari, Kiyan Heshmat-Ghahdarijani, Noushin Khalili
BACKGROUND: Subclinical hyperthyroidism (SHy) is a widespread condition in which cardiovascular manifestations are frequently occur, but there is still a debate about the vascular responsiveness in it. Measuring flow-mediated dilation (FMD) and intimae-media thickness (IMT) are used to evaluate endothelial function in these patients. MATERIALS AND METHODS: Twenty-five patients with a diagnosis of exogenous SHy and 25 full matched healthy subjects were enrolled. At first FMD of brachial artery and IMT of common carotid artery were obtained from all the participants...
2016: Advanced Biomedical Research
https://www.readbyqxmd.com/read/28028512/effect-of-teicoplanin-on-the-expression-of-c-myc-and-c-fos-proto-oncogenes-in-mcf-7-breast-cancer-cell-line
#19
Saeideh Ashouri, Maryam Hosseindokht Khujin, Mohammad Kazemi, Majid Kheirollahi
BACKGROUND: Teicoplanin is a member of vancomycin-ristocetin family of glycopeptide antibiotics. It mediated wound healing by increasing neovascularization possibly through activation of MAP kinase signaling pathway. The aim of this study is an evaluation of c-myc and c-fos genes expression after treatment of cells by teicoplanin and determines whether this glycopeptide antibiotic exerts its proliferation effects by influencing the expression of these genes. Hence, this study was designed to elucidate one possible mechanism underlying teicoplanin effects on cell proliferation using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazolium bromide (MTT) assay...
2016: Advanced Biomedical Research
https://www.readbyqxmd.com/read/28028511/assessment-of-a-2d-electronic-portal-imaging-devices-based-dosimetry-algorithm-for-pretreatment-and-in-vivo-midplane-dose-verification
#20
Ali Jomehzadeh, Parvaneh Shokrani, Mohammad Mohammadi, Alireza Amouheidari
BACKGROUND: The use of electronic portal imaging devices (EPIDs) is a method for the dosimetric verification of radiotherapy plans, both pretreatment and in vivo. The aim of this study is to test a 2D EPID-based dosimetry algorithm for dose verification of some plans inside a homogenous and anthropomorphic phantom and in vivo as well. MATERIALS AND METHODS: Dose distributions were reconstructed from EPID images using a 2D EPID dosimetry algorithm inside a homogenous slab phantom for a simple 10 × 10 cm(2) box technique, 3D conformal (prostate, head-and-neck, and lung), and intensity-modulated radiation therapy (IMRT) prostate plans inside an anthropomorphic (Alderson) phantom and in the patients (one fraction in vivo) for 3D conformal plans (prostate, head-and-neck and lung)...
2016: Advanced Biomedical Research
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