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Journal of Applied Biomaterials & Functional Materials

Wai-Ching Liu, Blake Ballenger, Amnah Algarni, Mariano Velez, Tien-Min G Chu
BACKGROUND: Bioactive glass has attracted substantial interest in orthopedics, but it has been less explored as a drug carrier. This study investigated the bovine serum albumin (BSA) release from bioactive 13-93B0 and 13-93B3 glasses. METHODS: Glass disks (13-93B0 and 13-93B3; n = 5) were loaded with 4 mg of BSA and coated under different chitosan-coating conditions. The amount of BSA released in phosphate-buffered saline (PBS) was evaluated, and a degradation study was performed to find out the weight loss and pH of PBS...
August 7, 2017: Journal of Applied Biomaterials & Functional Materials
Nina Bono, Paolo Tarsini, Gabriele Candiani
BACKGROUND: In recent decades, tooth derivatives such as dentin (D) and enamel (E) have been considered as potential graft biomaterials to treat bone defects. This study aimed to investigate the effects of demineralization on the physical-chemical and biological behavior of D and E. METHODS: Human D and E were minced into particles (Ø<1 mm), demineralized and sterilized. Thorough physical-chemical and biochemical characterizations of native and demineralized materials were performed by SEM and EDS analysis and ELISA kits to determine mineral, collagen type I and BMP-2 contents...
July 20, 2017: Journal of Applied Biomaterials & Functional Materials
(no author information available yet)
No abstract text is available yet for this article.
June 30, 2017: Journal of Applied Biomaterials & Functional Materials
Anna Morawska-Chochół, Patrycja Domalik-Pyzik, Elżbieta Menaszek, Jacek Sterna, Wojciech Bielecki, Joanna Bonecka, Maciej Boguń, Jan Chłopek
BACKGROUND: Commonly, intramedullary nails are made of nondegradable materials, and hence they need to be removed once the bone fracture is healed. We propose a novel composite material consisting of poly-L-lactide matrix modified with carbon and alginate fibers to be used for biodegradable intramedullary fixation. The aim of this study was to make in vitro and in vivo biocompatibility assessments. METHODS: In the in vitro conditions, biocompatibility of biomaterials was compared using normal human osteoblasts...
June 15, 2017: Journal of Applied Biomaterials & Functional Materials
Cigdem Guler, Ali Keles, Mehmet S Guler, Sendogan Karagoz, Ömer N Cora, Gul Keskin
BACKGROUND: Compomers are mostly used in primary dentition. The thermal conductivity properties of traditional or colored compomers have not been investigated in detail so far. The aim of this in vitro study was to assess and compare the thermal conductivities of traditional and colored compomers. METHOD: Two sets of compomers - namely, Twinky Star (available in berry, lemon, green, silver, blue, pink, gold and orange shades) and Dyract Extra (available in B1, A3 and A2 shades) - were included in this study...
June 15, 2017: Journal of Applied Biomaterials & Functional Materials
Joana Ferreira, Antonio Gloria, Stefania Cometa, Jorge F J Coelho, Marco Domingos
BACKGROUND: In recent years, the tissue engineering (TE) field has significantly benefited from advanced techniques such as additive manufacturing (AM), for the design of customized 3D scaffolds with the aim of guided tissue repair. Among the wide range of materials available to biomanufacture 3D scaffolds, poly(ε-caprolactone) (PCL) clearly arises as the synthetic polymer with the greatest potential, due to its unique properties - namely, biocompatibility, biodegradability, thermal and chemical stability and processability...
June 15, 2017: Journal of Applied Biomaterials & Functional Materials
Pietro Giorgi, Dario Capitani, Simone Sprio, Monica Sandri, Anna Tampieri, Valentina Canella, Angelo Nataloni, Giuseppe R Schirò
BACKGROUND: Spinal fusion is a common procedure used for surgical treatment of spinal deformity. In recent years, many bone graft substitutes (BGS) have been developed to provide good arthrodesis when the available autologous bone harvested from the patient is not enough. The aim of this study was to analyze the use of a new-generation composite material (RegenOss) made of Mg-hydroxyapatite nanoparticles nucleated on type I collagen to obtain long posterolateral fusion in adult scoliosis surgery...
June 7, 2017: Journal of Applied Biomaterials & Functional Materials
Qiang Luo, Yikun Pan, Ping Guo, Zhouhua Wang, Na Wei, Pengfei Sun, Yuxiao Liu
BACKGROUND: To demonstrate the adsorption strength of shale gas to calcium carbonate in shale matrix, the adsorption of shale gas on CaCO3 (100) surfaces was studied using the first-principles method, which is based on the density functional theory (DFT). METHODS: The structures and electronic properties of CH4, C2H6, CO2 and N2 molecules were calculated by the generalized gradient approximation (GGA), for a coverage of 1 monolayer (ML). Under the same conditions, the density of states (DOS) of CaCO3 (100) surfaces before and after the adsorption of shale gas molecules at high-symmetry adsorption sites were compared...
May 29, 2017: Journal of Applied Biomaterials & Functional Materials
Adriana Bigi, Elisa Boanini
The design and development of novel materials for biomineralized tissues is an extremely attractive field of research where calcium phosphates (CaPs)-based materials for biomedical applications play a leading role. The biological performance of these compounds can be enhanced through functionalization with biologically active ions and molecules. This review reports on some important recent achievements in creating functionalized biomimetic CaP materials for applications in the musculoskeletal field. Particular attention is focused on the modifications of these inorganic compounds with bioactive ions, growth factors and drugs, as well as on recent trends in some important CaP applications as biomaterials - namely, as bone cements, coatings of metallic implants and scaffolds for regenerative medicine...
May 29, 2017: Journal of Applied Biomaterials & Functional Materials
Chao Zhong, Likun Wang, Lei Qin, Yanjun Zhang
INTRODUCTION: To increase electromechanical coupling factor of 1-3 piezoelectric composite and reduce its bending deformation under external stress, an improved 1-3 piezoelectric composite is developed. In the improved structure, both epoxy resin and silicone rubber are used as polymer material. METHODS: The simulation model of the improved 1-3 piezoelectric composite was established using the finite element software ANSYS. The relationship of the performance of the improved composite to the volume percentage of silicone rubber was determined by harmonic response analysis and the bending deformation under external stress was simulated by static analysis...
May 29, 2017: Journal of Applied Biomaterials & Functional Materials
Miaolei Zhou, Yannan Zhang, Kun Ji, Dong Zhu
INTRODUCTION: Magnetically controlled shape memory alloy (MSMA) actuators take advantages of their large deformation and high controllability. However, the intricate hysteresis nonlinearity often results in low positioning accuracy and slow actuator response. METHODS: In this paper, a modified Krasnosel'skii-Pokrovskii model was adopted to describe the complicated hysteresis phenomenon in the MSMA actuators. Adaptive recursive algorithm was employed to identify the density parameters of the adopted model...
May 27, 2017: Journal of Applied Biomaterials & Functional Materials
Claudia C Camilo, Celey A E Silveira, Rafael S Faeda, João M D de Almeida Rollo, Benedito de Moraes Purquerio, Carlos Alberto Fortulan
BACKGROUND: Implants or implantable devices should integrate into the host tissue faster than fibrous capsule formation, in which the design of the interface is one of the biggest challenges. Generally, bioactive materials are not viable for load-bearing applications, so inert biomaterials are proposed. However, the surface must be modified through techniques such as coating with bioactive materials, roughness and sized pores. The aim of this research was to validate an approach for the evaluation of the tissue growth on implants of porous alumina coated with bioactive materials...
May 24, 2017: Journal of Applied Biomaterials & Functional Materials
Stanley C Onwubu, Anisa Vahed, Shalini Singh, Krishnan M Kanny
BACKGROUND: This study aimed to determine the physicochemical characteristics of an eggshell-based dental abrasive material. METHODS: The eggshell powder abrasive material (EPAM) was synthesized by ball milling eggshell powder and surfactants. Fourier transform infrared (FTIR) spectroscopy, X-ray diffraction (XRD), transmission electron microscopy (TEM) and a laser diffraction particle size analyzer (PSA) were used to characterize EPAM. In addition, the abrasive characteristics of EPAM were evaluated by comparison using poly(methyl methacrylate) (PMMA) resins...
May 24, 2017: Journal of Applied Biomaterials & Functional Materials
Anja Liebermann, Nicoleta Ilie, Malgorzata Roos, Bogna Stawarczyk
BACKGROUND: The aim of this study was to investigate the effects of storage medium and aging duration on Martens hardness (HM) and indentation modulus (EIT) of self-adhesive resin-based cements (SARCs). METHODS: A total of 416 discs were fabricated from 8 SARCs (n = 52 per SARC): (i) BeautyCem (BEA), (ii) Bifix SE (BIF), (iii) Clearfil SA Cement Automix (CLE), (iv) RelyX Unicem2 Automix (RXU), (v) SeT (SET), (vi) SmartCem 2 (SMC), (vii) SoloCem (SOC) and (viii) SpeedCEM (SPC)...
May 24, 2017: Journal of Applied Biomaterials & Functional Materials
Nilza G Ramião, Pedro S Martins, Maria L Barroso, Diana C Santos, António A Fernandes
BACKGROUND: The durability of breast implant material is associated with failure probability, increasing with time from implantation. The current study avoided the bias introduced by biological factors, to systematically investigate the degradation over time of shell materials. The same fundamental physical and chemical conditions were maintained (temperature and pH) throughout the study, to decouple biological aspects from the degradation process. METHODS: Six virgin implants of 2 brands were submitted to the in vitro degradation process, mechanical testing of shell materials, surface change analysis (via scanning electron microscopy [SEM]) and chemical composition analysis by Fourier transform infrared (FTIR) spectroscopy...
May 24, 2017: Journal of Applied Biomaterials & Functional Materials
(no author information available yet)
No abstract text is available yet for this article.
May 22, 2017: Journal of Applied Biomaterials & Functional Materials
Levent Demiriz, Ebru Hazar Bodrumlu
BACKGROUND: During the apexification procedure for teeth with open apices, mineral trioxide aggregate (MTA) may be unintentionally extruded. The aim of the present study was the retrospective evaluation of the healing of periapical lesions in permanent incisor teeth with open apices after the unintentional extrusion of MTA. METHODS: The clinical and radiographic records of 55 maxillary permanent central teeth treated by MTA apexification were evaluated. Filled teeth with unintentionally extruded MTA were selected as group 1 (n = 21), whereas the teeth with no MTA extrusion were selected as group 2 (n = 34)...
May 19, 2017: Journal of Applied Biomaterials & Functional Materials
Jiangting Li, Yufeng Peng, Xueyun Han, Shaoshuai Guo, Kunning Liang, Minggao Zhang
BACKGROUND: Sodium copper chlorophyllin (SCC), as one of the derivatives of chlorophyll - with its inherent green features; good stability for heat, light, acids and alkalies; unique antimicrobial capability; and particular deodori zation performance - is widely applied in some fields such as the food industry, medicine and health care, daily cosmetic industry etc. SCC, as one of the metal porphyrins, has attracted much attention because of its unique electronic band structure and photon conversion performance...
May 19, 2017: Journal of Applied Biomaterials & Functional Materials
Alessandro Scalise, Matteo Torresetti, Federica Verdini, Marianna Capecci, Elisa Andrenelli, Alessandro Mengarelli, Maria Gabriella Ceravolo, Sandro Fioretti, Giovanni Di Benedetto
BACKGROUND: Heel reconstruction represents a challenge for all plastic surgeons due to the anatomical and functional features of this weight-bearing area. In the last decade a combined use of acellular dermal matrices and skin grafts has been proposed as a reliable and less invasive alternative for complex wound management; nevertheless only a few cases have been reported in the literature. METHODS: We describe the long-term outcome of 2 cases of severe degloving trauma of the plantar region with massive soft tissue defects of the foot, that underwent surgical reconstruction with artificial dermis and skin grafts...
May 19, 2017: Journal of Applied Biomaterials & Functional Materials
Faiza Bukhari, Umar Ansari, Murtaza Najabat Ali, Hafsah Akhtar, Sarim Asif, Umer Mohammad, Mariam Mir
BACKGROUND: Auxetics, a special class of materials, tend to expand both in the radial and longitudinal directions when a unidirectional tensile force is applied. Recently, studies have come up with new designs for auxetic vascular and nonvascular stents which are deployed with commercial balloon catheters. There are some inherent limitations associated with a unidirectional application of expansion force in the effective deployment of stents. This work proposed a solution to some of these limitations through the use of a biaxial mode of a predetermined strain-based expansion mechanism...
July 27, 2017: Journal of Applied Biomaterials & Functional Materials
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