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Journal of Applied Biomaterials & Functional Materials

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https://www.readbyqxmd.com/read/28291900/study-of-mesenchymal-stem-cells-cultured-on-a-poly-lactic-co-glycolic-acid-scaffold-containing-simvastatin-for-bone-healing
#1
Dario Mendes Junior, Juliana A Domingues, Moema A Hausen, Silvia M M Cattani, Aguedo Aragones, Alexandre L R Oliveira, Rodrigo F Inácio, Maria L P Barbo, Eliana A R Duek
BACKGROUND: Tissue engineering is a promising alternative for the development of bone substitutes; for this purpose, three things are necessary: stem cells, a scaffold to allow tissue growth and factors that induce tissue regeneration. METHODS: To congregate such efforts, we used the bioresorbable and biocompatible polymer poly(lactic-co-glycolic acid) (PLGA) as scaffold. For the osteoinductive factor, we used simvastatin (SIM), a drug with a pleiotropic effect on bone growth...
March 8, 2017: Journal of Applied Biomaterials & Functional Materials
https://www.readbyqxmd.com/read/28256700/clinical-relevance-of-antimicrobial-testing-results-for-dental-restorative-materials
#2
Cher Farrugia, Julie Haider, Liberato Camilleri, Josette Camilleri
BACKGROUND: The antimicrobial activity of restorative materials is clinically relevant because all dental materials are subject to an environment containing bacteria. This study aimed to investigate the use of 2 methodologies referred to in the literature to assess antimicrobial properties of restorative materials and investigate whether material properties alter results of these traditional methodologies. METHODS: A number of dental restorative materials - namely, Chemfil Superior®, Spectrum®, Heliobond®, Ionoseal®, Dyract Extra®, Smart Dentin Replacement (SDR®) and Biodentine® - were characterized by scanning electron microscopy (SEM), energy-dispersive spectroscopy (EDS), X-ray diffraction (XRD) analysis, Fourier transform infrared (FT-IR) spectroscopy and pH analysis...
February 28, 2017: Journal of Applied Biomaterials & Functional Materials
https://www.readbyqxmd.com/read/28222206/titanium-hydroxyapatite-composites-sintered-at-low-temperature-for-tissue-engineering-in-vitro-cell-support-and-biocompatibility
#3
Romina Comín, Mariana P Cid, Luciano Grinschpun, Carlos Oldani, Nancy A Salvatierra
BACKGROUND: In clinical orthopedics, a critical problem is the bone tissue loss produced by a disease or injury. The use of composites from titanium and hydroxyapatite for biomedical applications has increased due to the resulting advantageous combination of hydroxyapatite bioactivity and favorable mechanical properties of titanium. Powder metallurgy is a simple and lower-cost method that uses powder from titanium and hydroxyapatite to obtain composites having hydroxyapatite phases in a metallic matrix...
February 21, 2017: Journal of Applied Biomaterials & Functional Materials
https://www.readbyqxmd.com/read/28165606/effect-of-topical-antiinflammatory-drugs-on-mechanical-behavior-of-rabbit-cornea
#4
Domenico Lepore, Roberto De Santis, Monica M Pagliara, Antonio Gloria, Olimpia Oliviero, Carlo Nucci, Giovanni Improta, Maria Triassi, Luigi Ambrosio
BACKGROUND: A variety of antiinflammatory therapies are employed to promote corneal wound healing. The effects of steroidal and nonsteroidal antiinflammatory drugs on the biomechanical properties of rabbit cornea were investigated over time using tensile tests. METHODS: Full-thickness incisions were made and used to analyze the effects of dexamethasone sodium phosphate 0.1% and diclofenac sodium 0.1% on corneal biomechanical properties during wound healing at 7, 14 and 21 days after surgery...
February 4, 2017: Journal of Applied Biomaterials & Functional Materials
https://www.readbyqxmd.com/read/28134971/engineering-thermoplastics-for-additive-manufacturing-a-critical-perspective-with-experimental-evidence-to-support-functional-applications
#5
Gianluca Cicala, Alberta Latteri, Barbara Del Curto, Alessio Lo Russo, Giuseppe Recca, Silvia Farè
BACKGROUND: Among additive manufacturing techniques, the filament-based technique involves what is referred to as fused deposition modeling (FDM). FDM materials are currently limited to a selected number of polymers. The present study focused on investigating the potential of using high-end engineering polymers in FDM. In addition, a critical review of the materials available on the market compared with those studied here was completed. METHODS: Different engineering thermoplastics, ranging from industrial grade polycarbonates to novel polyetheretherketones (PEEKs), were processed by FDM...
January 28, 2017: Journal of Applied Biomaterials & Functional Materials
https://www.readbyqxmd.com/read/28127744/electrochemical-anodizing-treatment-to-enhance-localized-corrosion-resistance-of-pure-titanium
#6
Davide Prando, Andrea Brenna, Fabio M Bolzoni, Maria V Diamanti, Mariapia Pedeferri, Marco Ormellese
BACKGROUND: Titanium has outstanding corrosion resistance due to the thin protective oxide layer that is formed on its surface. Nevertheless, in harsh and severe environments, pure titanium may suffer localized corrosion. In those conditions, costly titanium alloys containing palladium, nickel and molybdenum are used. This purpose investigated how it is possible to control corrosion, at lower cost, by electrochemical surface treatment on pure titanium, increasing the thickness of the natural oxide layer...
January 26, 2017: Journal of Applied Biomaterials & Functional Materials
https://www.readbyqxmd.com/read/28009420/clinical-outcomes-of-ceramicized-ball-heads-in-total-hip-replacement-bearings-a-literature-review
#7
REVIEW
Corrado Piconi, Vincenzo De Santis, Giulio Maccauro
BACKGROUND: Metallic ball heads for total hip replacement (THR) bearings with ceramicized surfaces were introduced in orthopedics during the second half of the 1980s, with the aim of decreasing the wear of polyethylene cups. METHODS: An analysis was made of the literature regarding outcomes for metallic ball heads with ceramicized surfaces now in clinical use (TiN, TiNbN, ZrN, monoclinic ZrO2), as well as carbon coatings (pyrolytic carbon, diamond-like carbon) and silicon nitride as coatings in ball heads for THR bearings...
January 26, 2017: Journal of Applied Biomaterials & Functional Materials
https://www.readbyqxmd.com/read/28009419/mesenchymal-stem-cells-from-reaming-material-possess-high-osteogenic-potential-and-react-sensitively-to-bone-morphogenetic-protein-7
#8
COMPARATIVE STUDY
Melanie Hoellig, Fabian Westhauser, Kira Kornienko, Kai Xiao, Gerhard Schmidmaier, Arash Moghaddam
BACKGROUND: Femoral material harvested using the Reamer-Irrigator-Aspirator (RIA) system is an alternative source for autogenous bone material in the treatment of non-unions, especially in combination with bone morphogenetic proteins (BMP). So far, there is no in vivo evidence of BMP-7 interacting with mesenchymal stem cells (MSCs) from RIA material (RIA-MSCs) and iliac crest autogenous bone (BMSCs). The aim of this study was to compare their osteogenic potential when stimulated with BMP-7 in vivo...
January 26, 2017: Journal of Applied Biomaterials & Functional Materials
https://www.readbyqxmd.com/read/27791230/myoblast-adhesion-proliferation-and-differentiation-on-human-elastin-like-polypeptide-help-hydrogels
#9
Paola D'Andrea, Deborah Civita, Michela Cok, Luisa Ulloa Severino, Francesca Vita, Denis Scaini, Loredana Casalis, Paola Lorenzon, Ivan Donati, Antonella Bandiera
BACKGROUND: The biochemical, mechanical and topographic properties of extracellular matrix are crucially involved in determining skeletal muscle cell morphogenesis, proliferation and differentiation. Human elastin-like polypeptides (HELPs) are recombinant biomimetic proteins designed to mimic some properties of the native matrix protein; when employed as myoblast adhesion substrates, they stimulate in vitro myogenesis. Given the influence that the biophysical properties of extracellular matrix have on skeletal muscle cells, the aim of this work was to investigate the effects of HELP hydrogels on myoblasts' viability and functions...
January 26, 2017: Journal of Applied Biomaterials & Functional Materials
https://www.readbyqxmd.com/read/27739575/mammalian-fibroblast-cells-show-strong-preference-for-laser-generated-hybrid-amorphous-silicon-sio2-textures
#10
Candace Colpitts, Amin M Ektesabi, Rachael A Wyatt, Bryan D Crawford, Amirkianoosh Kiani
BACKGROUND: In this study, we investigated a method to produce bioactive hybrid amorphous silicon and silicon oxide patterns using nanosecond laser pulses. METHODS: Microscale line patterns were made by laser pulses on silicon wafers at different frequencies (25, 70 and 100 kHz), resulting in ablation patterns with frequency-dependent physical and chemical properties. RESULTS: Incubating the laser-treated silicon substrates with simulated body fluid demonstrated that the physicochemical properties of the laser-treated samples were stable under these conditions, and favored the deposition of bone-like apatite...
January 26, 2017: Journal of Applied Biomaterials & Functional Materials
https://www.readbyqxmd.com/read/27716870/effect-of-cold-drawing-on-mechanical-properties-of-biodegradable-fibers
#11
Francesco Paolo La Mantia, Manuela Ceraulo, Maria Chiara Mistretta, Marco Morreale
PURPOSE: Biodegradable polymers are currently gaining importance in several fields, because they allow mitigation of the impact on the environment related to disposal of traditional, nonbiodegradable polymers, as well as reducing the utilization of oil-based sources (when they also come from renewable resources). Fibers made of biodegradable polymers are of particular interest, though, it is not easy to obtain polymer fibers with suitable mechanical properties and to tailor these to the specific application...
January 26, 2017: Journal of Applied Biomaterials & Functional Materials
https://www.readbyqxmd.com/read/27647392/anisotropy-in-the-viscoelastic-response-of-knee-meniscus-cartilage
#12
Luca Coluccino, Chiara Peres, Riccardo Gottardi, Paolo Bianchini, Alberto Diaspro, Luca Ceseracciu
BACKGROUND: The knee meniscus is instrumental to stability, shock absorption, load transmission and stress distribution within the knee joint. Such functions are mechanically demanding, and replacement constructs used in meniscus repair often fail because of a poor match with the surrounding tissue. This study focused on the native structure-mechanics relationships and on their anisotropic behavior in meniscus, to define the target biomechanical viscoelastic properties required by scaffolds upon loading...
January 26, 2017: Journal of Applied Biomaterials & Functional Materials
https://www.readbyqxmd.com/read/27647389/does-acid-etching-morphologically-and-chemically-affect-lithium-disilicate-glass-ceramic-surfaces
#13
Yukinori Maruo, Goro Nishigawa, Masao Irie, Kumiko Yoshihara, Takuya Matsumoto, Shogo Minagi
BACKGROUND: This study evaluated the surface morphology, chemical composition and adhesiveness of lithium disilicate glass ceramic after acid etching with hydrofluoric acid or phosphoric acid. METHODS: Lithium disilicate glass ceramic specimens polished by 600-grit silicon carbide paper were subjected to one or a combination of these surface treatments: airborne particle abrasion with 50-μm alumina (AA), etching with 5% hydrofluoric acid (HF) or 36% phosphoric acid (Phos), and application of silane coupling agent (Si)...
January 26, 2017: Journal of Applied Biomaterials & Functional Materials
https://www.readbyqxmd.com/read/27647387/measuring-the-remineralization-potential-of-different-agents-with-quantitative-light-induced-fluorescence-digital-biluminator
#14
Ebru Kucukyilmaz, Selcuk Savas
BACKGROUND: The aim of this study was to investigate the effectiveness of different remineralization agents by quantitative light-induced fluorescence digital BiluminatorTM (QLF-D). METHODS: Artificial caries lesions were created, and the teeth were divided according to the tested materials: (i) distilled water, (ii) acidulated phosphate fluoride (APF), (iii) Curodont Repair (CR), (iv) ammonium hexafluorosilicate (SiF) and (v) ammonium hexafluorosilicate plus cetylpyridinium chloride (SiF + CPC)...
January 26, 2017: Journal of Applied Biomaterials & Functional Materials
https://www.readbyqxmd.com/read/27647384/from-honeycomb-to-microsphere-patterned-surfaces-of-poly-lactic-acid-and-a-starch-poly-lactic-acid-blend-via-the-breath-figure-method
#15
Ana Rita C Duarte, Devid Maniglio, Nuno Sousa, João F Mano, Rui L Reis, Claudio Migliaresi
BACKGROUND: This study investigated the preparation of ordered patterned surfaces and/or microspheres from a natural-based polymer, using the breath figure and reverse breath figure methods. METHODS: Poly(D,L-lactic acid) and starch poly(lactic acid) solutions were precipitated in different conditions - namely, polymer concentration, vapor atmosphere temperature and substrate - to evaluate the effect of these conditions on the morphology of the precipitates obtained...
January 26, 2017: Journal of Applied Biomaterials & Functional Materials
https://www.readbyqxmd.com/read/27514495/use-of-autologous-epithelium-transplantation-on-various-scaffolds-to-cover-tissue-loss-in-oral-cavity-long-term-observation
#16
Bogusława Orzechowska-Wylęgała, Dariusz Dobrowolski, Domenico Puzzolo, Bogumił Wowra, Wiktor Niemiec, Adam Wylęgała, Krzysztof Szczubiałka
BACKGROUND: The aim of this study was to investigate the application of mucous membrane keratinocyte cultures on amniotic membrane and on poly(L-lactic acid) (PLLA) Purasorb PL38 to cover tissue loss in the oral cavity. Developments in molecular biology techniques and tissue engineering allow the culturing and identification of cells that can be anchored in the wound to achieve integrity of the tissue. Transplantation of tissues obtained from the patient's own cells is superior to allogenous transplantation where there is a possibility of transfection, rejection and the need for long-term immunosuppression...
January 26, 2017: Journal of Applied Biomaterials & Functional Materials
https://www.readbyqxmd.com/read/28009418/development-of-polymeric-functionally-graded-scaffolds-a-brief-review
#17
Roberto Scaffaro, Francesco Lopresti, Andrea Maio, Fiorenza Sutera, Luigi Botta
Over recent years, there has been a growing interest in multilayer scaffolds fabrication approaches. In fact, functionally graded scaffolds (FGSs) provide biological and mechanical functions potentially similar to those of native tissues. Based on the final application of the scaffold, there are different properties (physical, mechanical, biochemical, etc.) which need to gradually change in space. Therefore, a number of different technologies have been investigated, and often combined, to customize each region of the scaffolds as much as possible, aiming at achieving the best regenerative performance...
December 16, 2016: Journal of Applied Biomaterials & Functional Materials
https://www.readbyqxmd.com/read/27809331/development-of-a-photocatalytic-filter-to-control-indoor-air-quality
#18
Barbara Del Curto, Paolo Tarsini, Alberto Cigada
BACKGROUND: The aim of this work was the development and characterization of a photocatalytic filter for the treatment of indoor air, characterized by a low pressure drop. METHODS: The filter (photocatalytic filter) was based on a polyester substrate additivated with active carbon (Carbotex 150-6), treated with a sol of titanium dioxide (Sol 121-AB; NextMaterials Ltd.) and illuminated with UV LEDs to induce photocatalytic activity. RESULTS: Tests showed that this filter, used in a suitable device for air circulation with a very low noise level, had the ability to block solid particulates, to photocatalytically oxidize a major fraction of volatile organic compounds (VOCs) and deactivate all of the bacteria blocked on the filter, in contrast to traditional commercial air filters on which the bacteria remain viable...
November 2, 2016: Journal of Applied Biomaterials & Functional Materials
https://www.readbyqxmd.com/read/27809330/poly-paper-a-sustainable-material-for-packaging-based-on-recycled-paper-and-recyclable-with-paper
#19
Barbara Del Curto, Nadia Barelli, Mauro Profaizer, Silvia Farè, Maria Cristina Tanzi, Alberto Cigada, Giulia Ognibene, Giuseppe Recca, Gianluca Cicala
BACKGROUND: Until now, environmental sustainability issues are almost entirely unsolved for packaging materials. With the final aim of finding materials with a single recycling channel, cellulose fiber/poly(vinyl)alcohol composites were investigated. METHODS: After extrusion and injection molding, samples of composite with different cellulose fiber content (30%, 50% and 70% w/w) were tested. RESULTS: Tensile mechanical tests exhibited an improvement in composite stiffness when the reinforcement content was increased together with a decrease in composite elongation...
November 2, 2016: Journal of Applied Biomaterials & Functional Materials
https://www.readbyqxmd.com/read/27716872/bioencapsulation-technologies-in-tissue-engineering
#20
REVIEW
Rebecca L Majewski, Wujie Zhang, Xiaojun Ma, Zhanfeng Cui, Weiping Ren, David C Markel
Bioencapsulation technologies have played an important role in the developing successes of tissue engineering. Besides offering immunoisolation, they also show promise for cell/tissue banking and the directed differentiation of stem cells, by providing a unique microenvironment. This review describes bioencapsulation technologies and summarizes their recent progress in research into tissue engineering. The review concludes with a brief outlook regarding future research directions in this field.
November 2, 2016: Journal of Applied Biomaterials & Functional Materials
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