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Annals of Palliative Medicine

José António Ferraz Gonçalves, Clara Castro, Paula Silva, Rui Carneiro, Catarina Simões, Isabel Costa
OBJECTIVE: Many assessment tools have been developed for palliative care and there are a number of differences between them. Therefore, we felt that there was room for improvement. METHODS: In a previous study, the relevant items were selected by a Delphi process with international experts in palliative care. A 5-point verbal scale was added to the items selected and adapted to the different kind of items. RESULTS: The study included 123 patients, 63 (51%) were female and the median age was 64 (37 to 88)...
September 22, 2016: Annals of Palliative Medicine
Erin Wong, Leigha Rowbottom, May Tsao, Liying Zhang, Rachel McDonald, Cyril Danjoux, Elizabeth Barnes, Stephanie Chan, Edward Chow
OBJECTIVE: Having a clear prognosis for patients with brain metastases allows health care practitioners (HCPs) to determine appropriate palliative management and assist patients when making informed treatment decisions. The objective of this study was to determine the prognostic significance of commonly experienced symptoms as well as their changes. METHODS: Overall survival (OS) was calculated from the date of consultation for palliative radiotherapy to date of death or censored at last follow-up date...
September 9, 2016: Annals of Palliative Medicine
Eric Ojerholm, Charles B Simone
No abstract text is available yet for this article.
September 7, 2016: Annals of Palliative Medicine
William B Weeks, Bruno Ventelou, Marc Karim Bendiane
OBJECTIVE: Recently, French policymakers have tried to improve care at the end-of-life, by improving access to community-based palliative care, particularly for patients with cancer and neurological diseases. If effective, these efforts should reduce the proportion of such patients who die in the hospital. In light of these policies, we sought to determine the effectiveness of these efforts on reducing inpatient deaths by conducting a retrospective, observational analysis of patients aged 65 and older who were admitted to hospitals in France between 2010 and 2013 for 1 of 3 non-surgical conditions...
September 5, 2016: Annals of Palliative Medicine
Eva Katharina Masel, Sophie Schur, Romina Nemecek, Michael Mayrhofer, Patrick Huber, Feroniki Adamidis, Bruno Maehr, Matthias Unseld, Herbert Hans Watzke, Robert Pirker
OBJECTIVE: Palliative care plays a crucial role in the overall management of patients with advanced lung cancer and was shown to lead to clinically meaningful improvement in quality of life, less aggressive endof-life care, and potentially prolonged survival. Here we summarize our single institution experience on palliative care in patients with lung cancer. METHODS: The data of patients with lung cancer treated at the palliative care unit of the Medical University of Vienna between June 2010 and March 2013 were retrospectively reviewed...
September 1, 2016: Annals of Palliative Medicine
May N Tsao, Emily Sinclair, Dalal Assaad, Jeff Fialkov, Oleh Antonyshyn, Elizabeth Barnes
OBJECTIVE: Kaposi sarcoma (KS) lesions are purplish, reddish blue or dark brown/black macules, plaques or nodules which involve the skin and occasionally internal organs. Most patients with KS have a long indolent chronic course. METHODS: A retrospective review was undertaken for all KS skin patients treated with radiotherapy at a tertiary cancer centre from Jan. 2, 1999 to Dec. 31, 2014 (inclusive). RESULTS: A total of 47 patients with KS (43 classical, 0 African, 1 iatrogenic, 3 AIDS related) were seen in the multidisciplinary clinic...
August 25, 2016: Annals of Palliative Medicine
Deepti Ahuja, Sachidanand J Bharati, Nishkarsh Gupta, Ritesh Kumar, Sushma Bhatnagar
Radiation-induced nausea and vomiting (RINV) is one of the most distressing symptoms that adversely affects quality of life (QOL) as well as the ongoing management plan of cancer patients. Although there are protocols for management of chemotherapy induced nausea and vomiting (CINV) but such guidelines are still lacking for RINV. Various agents like 5-hydroxy tryptophan 3 (5-HT3) antagonist, dexamethasone, metoclopramide and haloperidol are used in clinical practice for RINV but the results are not very encouraging...
August 23, 2016: Annals of Palliative Medicine
Chun-Yan So, Kwok-Ying Chan, Ho-Yan Au, Man-Lui Chan, Theresa Lai
Superior mesenteric artery (SMA) syndrome is an uncommon cause of intestinal obstruction and seldom been mentioned in palliative care. Hereby, we reported a case of SMA syndrome who presented with symptoms of upper intestinal obstruction in a 68-year-old patient; subsequent CT findings were classical of SMA syndrome. The patient's history of poliomyelitis and recent significant weight loss were the predisposing factors for SMA syndrome. It also highlights the importance of monitoring signs and symptoms of intestinal obstruction in such patients before considering switching to oral feeding...
July 14, 2016: Annals of Palliative Medicine
Charles B Simone
No abstract text is available yet for this article.
July 2016: Annals of Palliative Medicine
Catherine Riffin, Cara Kenien, Angela Ghesquiere, Ashley Dorime, Carolina Villanueva, Daniel Gardner, Jean Callahan, Elizabeth Capezuti, M Carrington Reid
Concern over the need for effective and accessible healthcare for individuals with advanced chronic illness has drawn attention to the significant gaps in our knowledge of palliative medicine. To advance our understanding of this field, community-based participatory research (CBPR) is proposed as a tool for future research initiatives. This paper offers a rationale for how CBPR may be employed to address specific gaps in palliative care research. Several examples where this approach has been used previously are described, and potential obstacles to implementing this research method are delineated...
July 2016: Annals of Palliative Medicine
Danielle Rodin, Surbhi Grover, Shekinah N Elmore, Felicia M Knaul, Rifat Atun, Lisa Caulley, Cristian A Herrera, Joshua A Jones, Aryeh J Price, Anusheel Munshi, Ajeet K Gandhi, Chiman Shah, Mary Gospodarowicz
Radiotherapy (RT) is a powerful tool for the palliation of the symptoms of advanced cancer, although access to it is limited or absent in many low- and middle-income countries (LMICs). There are multiple factors contributing to this, including assumptions about the economic feasibility of RT in LMICs, the logical challenges of building capacity to deliver it in those regions, and the lack of political support to drive change of this kind. It is encouraging that the problem of RT access has begun to be included in the global discourse on cancer control and that palliative care and RT have been incorporated into national cancer control plans in some LMICs...
July 2016: Annals of Palliative Medicine
Alyssa Yeager, Anna W LaVigne, Ambika Rajvanshi, Birbal Mahato, Ravinder Mohan, Reena Sharma, Surbhi Grover
BACKGROUND: According to the 2014 WHO Global Atlas of Palliative Care, there is insufficient access to palliative care services worldwide, with the majority of unmet need in low- and middle-income countries. In India, there are major disparities in access to palliative care, with the majority of services being offered by non-governmental organizations (NGOs) scattered throughout the country. The barriers to expanding palliative care services in India are common to many lower- and middle-income countries-a lack of financial resources, a paucity of trained staff, and a focus on curative rather than comfort care...
July 2016: Annals of Palliative Medicine
Charles B Simone
No abstract text is available yet for this article.
July 2016: Annals of Palliative Medicine
Natália Miki-Rosário, Reynaldo Jesus Garcia Filho, Jairo Greco Garcia, Gal Moreira Dini, Andrew Bottomley, Edward Chow, Miguel Sabino Neto
BACKGROUND: The aim of the present study was to conduct a cross-cultural adaptation (with translation into Brazilian Portuguese) and validation of the European Organization for Research and Treatment of Cancer-Quality of Life Questionnaire-Bone Metastases-22 (EORTC QLQ-BM22). METHODS: Ninety-five bone metastasis patients (31 men and 64 women, mean age 58.36±8.90 years) took part in the investigation. The translation guide of the EORTC was used to translate from English into Brazilian Portuguese and adapt the instrument culturally...
July 2016: Annals of Palliative Medicine
Stephanie Chan, Leigha Rowbottom, Rachel McDonald, Elizabeth David, Hans Chung, Albert Yee, Angela Turner, Edward Chow
Insufficiency fractures are stress fractures that occur from normal weight-bearing on weakened bone. Radiation treatment to malignancies in the prostate, rectum, anus, or cervix may increase the risk of insufficiency fractures in the pelvic region by damaging osteoblasts that are essential to bone formation. In elderly women with cancer, this risk is greater due to their susceptibility to developing osteoporosis. These fractures may be confused with pathological fractures resulting from bone metastases on imaging and should be identified for proper management...
July 2016: Annals of Palliative Medicine
Sushma Bhatnagar, Mayank Gupta
Pain is one of the most common, distressing and feared symptom among cancer and other patients in need of palliative care. An estimated 25% of cancer patients and 25 million people die in pain each year. Effective pain and symptom management are the core elements of palliative care which aims at reducing suffering and improving quality of life (QOL) throughout the course of illness starting from diagnosis, in sync with curative treatments and at end of life. There is a prevailing shortage of manpower apt to deal with pain and providing cost-effective palliative care and with the rise of cancer, other chronic diseases and explosion of new life-prolonging therapeutic modalities, this 'Patient-pain and palliative physician' discrepancy is only going to increase, more so in developing countries...
July 2016: Annals of Palliative Medicine
Tasneem Barakat, Arnav Agarwal, Rachel McDonald, Vithusha Ganesh, Sherlyn Vuong, Michael Borean, Edward Chow, Hany Soliman
Brain metastases arising from prostate cancer are exceedingly rare and typically occur late in the course of the disease. Most patients have widespread metastatic disease before developing brain metastases from prostate cancer. We report the case of a 67-year-old male with prostate cancer presenting with an isolated symptomatic brain metastasis. Aggressive treatment of the metastatic site included tumor resection and adjuvant stereotactic radiation treatment (RT) to the surgical bed, resulting in a favorable outcome...
July 2016: Annals of Palliative Medicine
Andrew Toyin Olagunju, Foluke Oladele Sarimiye, Tinuke Oluwasefunmi Olagunju, Muhammad Yaqub Murtazha Habeebu, Olatunji Francis Aina
BACKGROUND: Childhood cancers evoke various emotional reactions in caregivers which can impair their well-being and roles. Little is known about caregiving and which cancer-associated factors are related to caregiver's depression in resource-restricted settings. We sought to investigate if child's symptom burden is related to depressive symptoms in caregivers. METHODS: Seventy-two caregivers and children with cancers were administered questionnaires to elicit socio-demographic and disease-related data...
July 2016: Annals of Palliative Medicine
Ronald Chow, Saurabh Ray, May Tsao, Natalie Pulenzas, Liying Zhang, Arjun Sahgal, David Cella, Hany Soliman, Cyril Danjoux, Carlo DeAngelis, Sherlyn Vuong, Rachel McDonald, Edward Chow
BACKGROUND: To examine the baseline characteristics of patients who underwent different treatments for brain metastases. METHODS: Allocated into group A [whole brain radiation therapy (WBRT) alone], or group B [stereotactic radiosurgery (SRS) or neurosurgery with or without WBRT], brain metastases patients with assigned treatment completed the Brain Symptom and Impact Questionnaire (BASIQ). Items of BASIQ were arranged as a symptom score or function score. RESULTS: Lung, breast, melanoma and renal cancer were the most prevalent primary cancer site among the study population, with 91 (53%), 25 (15%), 17 (10%) and 15 (9%) patients, respectively...
July 2016: Annals of Palliative Medicine
Leonard Chiu, Nicholas Chiu, Ronald Chow, Liying Zhang, Mark Pasetka, Jordan Stinson, Breanne Lechner, Natalie Pulenzas, Sunil Verma, Edward Chow, Carlo DeAngelis
BACKGROUND: While the efficacy of olanzapine in the prophylaxis of chemotherapy-induced nausea and vomiting (CINV) has been documented, the literature on the use of olanzapine as a rescue medication for breakthrough CINV has been scarce. The following study retrospectively evaluated the safety and efficacy of olanzapine for the treatment of breakthrough CINV. The efficacy and safety of olanzapine in the prophylactic setting was also examined in a smaller cohort. METHODS: Electronic medical records of adult patients aged >17 years receiving a prescription for olanzapine from the Odette Cancer Centre Pharmacy at Sunnybrook Hospital between January 2013 and June 2015 were reviewed retrospectively...
July 2016: Annals of Palliative Medicine
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