Guilherme R F Campos, Nathalie Bonatti Franco Almeida, Priscilla Soares Filgueiras, Camila Amormino Corsini, Sarah Vieira Contin Gomes, Daniel Alvim Pena de Miranda, Jéssica Vieira de Assis, Thaís Bárbara de Souza Silva, Pedro Augusto Alves, Gabriel da Rocha Fernandes, Jaquelline Germano de Oliveira, Paula Rahal, Rafaella Fortini Queiroz Grenfell, Maurício L Nogueira
INTRODUCTION: SARS-CoV-2 vaccines production and distribution enabled the return to normalcy worldwide, but it was not fast enough to avoid the emergence of variants capable of evading immune response induced by prior infections and vaccination. This study evaluated, against Omicron sublineages BA.1, BA.5 and BQ.1.1, the antibody response of a cohort vaccinated with a two doses CoronaVac protocol and followed by two heterologous booster doses. METHODS: To assess vaccination effectiveness, serum samples were collected from 160 individuals, in 3 different time points (9, 12 and 18 months after CoronaVac protocol)...
2024: Frontiers in Cellular and Infection Microbiology