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Annals of Medical and Health Sciences Research

G S Dharmshaktu, I Khan
No abstract text is available yet for this article.
May 2016: Annals of Medical and Health Sciences Research
Muzaffar Maqsood Wani, Imran Khan, Riyaz Ahmad Bhat, Muzaffar Ahmad
Fabry's disease is an X-linked lysosomal storage disorder caused by a deficiency of alpha-galactosidase A enzyme with the progressive accumulation of globotriaosylceramide in vascular endothelial cells leading to cardiovascular, renal, gastrointestinal, neuropathic, lenticular, and dermatological manifestations. It is a rare cause of end-stage renal disease. It classically affects males whereas 10-15% of female heterozygote carriers are affected depending on localization. Both the FD and its association with ESRD is rare...
May 2016: Annals of Medical and Health Sciences Research
A O Atolagbe, O Ogunleye, C T Apakama
Perirectal epidermoid cysts are congenital cysts originating from the ectodermal germ cell layer of the hind gut. Their presenting symptoms are most often nonspecific and distinguishing them from other presacral developmental cysts often present a diagnostic and therapeutic dilemma. We present a 58-year-old woman who presented with chronic dyschezia and hematochezia of a few days duration and no prior colonoscopies. Initial blood work and tumor markers were unremarkable. Pelvic magnetic resonance imaging (MRI) showed a 7...
May 2016: Annals of Medical and Health Sciences Research
A Herur, S Kolagi, U Ramadurg, C S Hiremath, C P Hadimani, S S Goudar
BACKGROUND: A gap between best practice and actual clinical care exists and this can be overcome by evidence-based practice (EBP), which is essential to improve the clinical decision making. A strategy to reduce deficits in care provision is to train the postgraduate students in the practice of EBP in the journal clubs as evidence from medical colleges in India reveals that current format of journal club presentations is unsatisfactory. AIM: The aim of the present study was to refine the journal club presentations of postgraduate students of clinical departments and to study the effectiveness of EBP training in them for better EBP...
May 2016: Annals of Medical and Health Sciences Research
P Premalatha, I V Renuka, A Meghana, S I Devi, Pavk Charyulu, G Sampoorna
Leprosy, a relatively common chronic contagious disease having diverse modes of clinical presentation, can mimic a variety of unrelated diseases. For proper and adequate treatment, the diagnosis must be made accurately with subtyping which should be done with the help of bacillary index, histopathological features, and clinical correlation. This is extremely important in patient care as paucibacillary and multibacillary types have different modes of treatment. Our aim is to categorize leprosy into various types based on bacillary index, morphological findings both in slit skin smears, and biopsy along with clinical correlation...
May 2016: Annals of Medical and Health Sciences Research
M B Shobha, Sai Ajs, Kmg Manoj, E Srideevi, M Sridhar, Gmjs Pratap
BACKGROUND: Most of the universally accepted mixed dentition analyses are based on the data derived from northwestern European descent. However, the accuracy of these methods when applied to different ethnic population is questionable. AIM: The present study is aimed to evaluate the applicability of Tanaka and Johnston (TJ) and Moyers (50(th) and 75(th) percentile) mixed dentition analysis in a sample from south-eastern region of Andhra Pradesh, India. SUBJECTS AND METHODS: Study models were prepared from a sample of 100 patients (50 males and 50 females) in the age range of 13-15 years...
May 2016: Annals of Medical and Health Sciences Research
E C Ejim, N I Oguanobi
BACKGROUND: Pulmonary hypertension is a common complication of degenerative mitral valve disease, and contributes significantly to both morbidity and mortality. The use of medications for reduction of pulmonary pressure in patients is not a common practice by most physicians in this part of the world because of the absence of data on pulmonary hypertension. AIM: The authors set out to find the prevalence of pulmonary hypertension in patients with degenerative mitral valve disease and to determine if there are gender differences in affectation...
May 2016: Annals of Medical and Health Sciences Research
B O Edelu, O I Odetunde, C B Eke, N A Uwaezuoke, T Oguonu
BACKGROUND: Accidental childhood poisoning is one of the recognized causes of morbidity and mortality in children under the age of 5 years worldwide. The prevalence and type of substance ingested vary from place to place and over time. AIM: This study was conducted with the aim of ascertaining the frequency and pattern of accidental childhood poisoning in Enugu. SUBJECTS AND METHODS: This retrospective study was conducted at the Emergency Paediatric Unit of the University of Nigeria Teaching Hospital, Enugu, South-East, Nigeria from January 2003 to December 2012 (10 years)...
May 2016: Annals of Medical and Health Sciences Research
M N Moghadam, M Motamedifar, J Sarvari, Ebrahim-Saraie H Sedigh, Same M Mousavi, F N Moghadam
BACKGROUND: Metallo-beta-lactamase (MβL) enzymes production is one of the most important resistance mechanisms against carbapenems in some bacteria including Acinetobacter baumannii. AIMS: This study was aimed to determine the antimicrobial susceptibility and the prevalence of MβL among carbapenem-resistant isolates of A. baumannii. MATERIALS AND METHODS: In this cross-sectional study from October 2012 to April 2013, 98 isolates were identified as A...
May 2016: Annals of Medical and Health Sciences Research
C B Eke, S O Ogbodo, O M Ukoha, V U Muoneke, R C Ibekwe, A N Ikefuna
BACKGROUND: Although children comprise a small fraction of the burden of hepatitis C virus (HCV) infections, which is a major global health challenge, a significant number of them develop chronic HCV infection and are at risk of its complications. AIM: The aim of the current study was to determine the prevalence and associated factors of HCV infection in school children in Enugu urban. SUBJECTS AND METHODS: This was a cross-sectional seroepidemiological study involving children aged 10-18 years selected using multistage systematic sampling in Enugu metropolis, Southeast Nigeria...
May 2016: Annals of Medical and Health Sciences Research
R N Vanitha, S Kavimani, P Soundararajan, D Chamundeeswari, G Kannan, S Rengarajan
BACKGROUND: Malnutrition and inflammation are associated with morbidity and mortality in patients on maintenance hemodialysis (MHD). Ghrelin, an orexigenic peptide hormone, is speculated to be associated with nutritional and inflammatory status in MHD. AIM: To assess the serum total ghrelin levels and its possible relationship with inflammation and nutritional status in patients on MHD. SUBJECTS AND METHODS: The study was conducted on 90 patients on MHD for 6 months and above (56 males, 34 females, mean age 52...
May 2016: Annals of Medical and Health Sciences Research
A S Elhwuegi
The Nobel Prize winning discovery of nitric oxide (NO) in 1986 was the starting point for a new innovation in drug discovery. NO acting as a mediator at different physiological systems is believed to be involved in many physiological and pathological conditions through the formation of the second messenger cyclic guanosine monophosphate (cGMP). cGMP-dependent vasodilation effect of NO is important in regulating pulmonary and systemic pressures, maintaining penis erection, preventing atherosclerosis, preventing platelet aggregation, and protecting and controlling cardiac functions...
May 2016: Annals of Medical and Health Sciences Research
S Bahadur, M Pujani, S Jetley
No abstract text is available yet for this article.
March 2016: Annals of Medical and Health Sciences Research
O M Gbotolorun, C I Emeka, O Effiom, R A Adewole, A S Ayodele
Oro-facial malignancies are reported to have a high mortality and morbidity, this is further worsened when patient report late. To analyze the malignant oro-facial lesions seen at a Hospital in the Lagos, Nigeria. Successive patients that presented in the hospital and met criteria of study during 15 months period were recruited into the study. Demographics, clinical variables, and treatment provided for each patient in the hospital was recorded. Data collected were presented as tables and percentages. There were 36 cases seen, their ages ranged from 10 to 72 years (median 49 years), and there were 21 males and 15 females...
March 2016: Annals of Medical and Health Sciences Research
Phd Vaaka, S K Donga, A K Ganapathi, Priya B Devi, Sreeha Kaluvakolanu, Ziauddin Mohammad
Construction of complete denture with adequate retention is a complex procedure. Use of suction cup in a maxillary denture is one of the techniques to improve retention. Palatal Suction cup, which provides high retention by inducing negative pressure on the mucosal surface, is not being recommended because of its pathological effect on the palatal tissues leading to palatal perforation. Surgical closure of palatal perforation is challenging, technique sensitive, and it can be achieved by different surgical methods depending on the size and location of the defect...
March 2016: Annals of Medical and Health Sciences Research
M O Iroezindu, E O Ofondu, G C Mbata, B van Wyk, H P Hausler, Au Dh, L Lynen, P C Hopewell
BACKGROUND: Tuberculosis (TB) causes significant morbidity/mortality among human immunodeficiency virus-infected individuals in Africa. Reducing TB burden in the era of highly active antiretroviral therapy (HAART) is a public health priority. AIM: We determined the factors associated with prevalent TB among patients receiving HAART. SUBJECTS AND METHODS: We conducted a cross-sectional study of adult patients who had received HAART for ≥12 weeks in a Nigerian tertiary hospital...
March 2016: Annals of Medical and Health Sciences Research
S Sharma, A Agarwal, A M Khan, G K Ingle
BACKGROUND: Rabies is a fatal disease of the central nervous system caused by the bites of warm-blooded animals. One of the important methods of controlling rabies is by interventions to limit the number of dog bites, the most common source of transmission of rabies to humans in the community. Community-based data on dog bites are rare from India. AIM: The aim of this study is to determine the prevalence of dog bites and knowledge and practices relating to its management and prevention in an urban and a rural slum of North West Delhi, India...
March 2016: Annals of Medical and Health Sciences Research
E A Ugwa
BACKGROUND: Food taboos among rural women have been identified as one of the factors contributing to maternal undernutrition in pregnancy. AIM: The aim of this study was to explore some of the taboos and nutritional practices among pregnant women attending antenatal care at a General Hospital in Dawakin Kudu LGA, Kano, Nigeria. SUBJECTS AND METHODS: This was a cross-sectional study involving 220 pregnant women. Interviewer-administered structured questionnaire was used to interview the respondents, which showed various sociodemographic information, cultural nutritional processes, taboos of the community, and a 24 h food recall...
March 2016: Annals of Medical and Health Sciences Research
B Mbwele, A Slot, Q De Mast, P Kweka, M Msuya, M Hulscher
BACKGROUND: Evaluations of the guidelines for the management of Lower Respiratory Tract Infections (LRTI) Sub-Saharan Africa, particularly in Tanzania is scant. AIM: The aim of the study was to assess the usefulness of the current Tanzanian treatment guideline for the management lower respiratory tract infection. SUBJECTS AND METHODS: A descriptive cross sectional study in 11 hospitals of different levels in the Kilimanjaro region Data were collected from May 2012 to July 2012 by semi-structured interview for clinicians using 2 dummy cases for practical assessment...
March 2016: Annals of Medical and Health Sciences Research
K C Iregbu, P I Nwajiobi-Princewill
BACKGROUND: Hepatitis B viral infection is an old medical problem with worldwide distribution. It is usually diagnosed using serologic methods. However, the decision as to which patient to treat or not remains challenging due to the poor sensitivity of serologic markers as prognostic or severity markers. Viral load (VL) determination using polymerase chain reaction techniques is a useful tool in decision-making. AIM: To determine the proportion of hepatitis B-positive patients who fall into different care groups based on the Society for Gastroenterology and Hepatology in Nigeria (SOGHIN) and National Institute for Health and Care Excellence guidelines, respectively, using result of hepatitis B virus (HBV) DNA determination...
March 2016: Annals of Medical and Health Sciences Research
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