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Avicenna Journal of Medicine

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https://www.readbyqxmd.com/read/28469993/left-ventricular-noncompaction-cardiomyopathy
#1
Amer Hawatmeh, Habib Habib, Fayez Shamoon
No abstract text is available yet for this article.
April 2017: Avicenna Journal of Medicine
https://www.readbyqxmd.com/read/28469992/hyperthyroidism-and-noncompaction
#2
Josef Finsterer, Claudia Stöllberger
No abstract text is available yet for this article.
April 2017: Avicenna Journal of Medicine
https://www.readbyqxmd.com/read/28469991/donor-transmitted-melanoma-after-limbal-stem-cell-transplantation
#3
Anas Alsara, Muhammad Rafi
Limbal Stem Cells are a unique cell line located at the corneal limbus. They are responsible for regenerating and restoring corneal epithelial layers. Limbal stem cell transplantation is a promising technique that has been used to treat several hereditary and acquired corneal diseases. Cornea tissue lack vascularity. Hence, there were no special restrictions on collecting ocular tissues from donors with a diagnosis of metastatic melanoma. We are reporting a case of a patient who developed an ocular melanoma after she had limbal stem cell transplantation from a donor with history of melanoma...
April 2017: Avicenna Journal of Medicine
https://www.readbyqxmd.com/read/28469990/isolated-palatal-weakness-without-optic-neuritis-as-the-presenting-manifestation-of-multiple-sclerosis-and-its-diagnostic-dilemma-with-acute-disseminated-encephalomyelitis-in-a-young-boy
#4
Virti D Shah, Sumeet Prakash Mirgh, Nirmal Surya
We present a case of a young boy who at initial presentation was diagnosed as acute disseminated encephalomyelitis (ADEM) but subsequently on follow-up was diagnosed as multiple sclerosis (MS). Differentiating ADEM from MS in their first presentation can be tricky as the features may not be typical of anyone. The importance lies in the close follow-up of these patients.
April 2017: Avicenna Journal of Medicine
https://www.readbyqxmd.com/read/28469989/drug-induced-hypersensitivity-reaction-a-case-of-simultaneous-thyroiditis-and-fulminant-type-1-diabetes
#5
Michael Marchese, Matthew Leinung, Hassan Shawa
A 43-year-old incarcerated man with AIDS was hospitalized for 30 pounds weight loss and diffuse pruritic rash. Three months prior, he was started on dapsone for Pneumocystis jiroveci pneumonia prevention. Biochemical evaluation was remarkable for eosinophilia, thrombocytopenia, acute renal insufficiency, transaminitis, thyrotoxicosis, and significant hyperglycemia (450 mg/dl; nl, 65-99). His hemoglobin A1c level was 5.9% (nl, 4.1-5.6). Thyroid-stimulating immunoglobulin, glutamic acid decarboxylase, and islet cell autoantibodies were within the normal range...
April 2017: Avicenna Journal of Medicine
https://www.readbyqxmd.com/read/28469988/polio-in-syria-problem-still-not-solved
#6
Ahmad Al-Moujahed, Fares Alahdab, Heba Abolaban, Leo Beletsky
The reappearance of polio in Syria in mid-2013, 18 years after it was eliminated from the country, manifests the public health catastrophe brought on by the civil war. Among the lessons learned, this outbreak emphasizes the importance of increasing the international financial and logistical support for vaccine and immunization efforts, especially in countries suffering from conflicts. The lack of access to polio accredited laboratory or outright lack of laboratories in settings of conflict should be recognized allowing international surveillance to be strengthened by supplementing the laboratory definition with the clinical definition...
April 2017: Avicenna Journal of Medicine
https://www.readbyqxmd.com/read/28469987/efficacy-of-a-multi-component-psychosocial-intervention-program-for-caregivers-of-persons-living-with-neurocognitive-disorders-alexandria-egypt-a-randomized-controlled-trial
#7
Zeinab Nazeeh Shata, Marwa R Amin, Heba M El-Kady, Mervat W Abu-Nazel
BACKGROUND: Unlike other chronic diseases, dementia caregiving is associated with enormous psychological burden, which stresses the need for caregivers-directed psychosocial interventions. Aim: This randomized controlled trial (RCT) was conducted to evaluate the short-term efficacy of a multi-component psychosocial intervention program for informal caregivers of persons with neurocognitive disorders in Alexandria, Egypt. METHODS: Informal caregivers (120) were randomly assigned into intervention and control groups...
April 2017: Avicenna Journal of Medicine
https://www.readbyqxmd.com/read/28469986/black-widow-spider-bites-experience-from-tertiary-care-center-in-saudi-arabia
#8
Ali Al Bshabshe, Musa Alfaifi, Ahmed Fouad Alsayed
INTRODUCTION: Black widow spiders are one of the most poisonous species to humans; there are more than 30 species of widow spiders in the globe but good thing that not all of them are dangerous. Some of these spiders produce toxic venoms, which cause broad spectrum of clinical manifestations including skin lesions, neurotoxicity, cardiac toxicity and death in some occasions. In Saudi Arabia there were no much reports of black widow spider bites apart from the case series by BUCUR and his group in ALBAHA region...
April 2017: Avicenna Journal of Medicine
https://www.readbyqxmd.com/read/28469985/are-these-results-trustworthy-a-guide-for-reading-the-medical-literature
#9
REVIEW
Fares Alahdab, Allison Morrow, Mouaz Alsawas, M Hassan Murad
Physicians practicing evidence-based medicine need to be able to appraise a new study and determine whether the results warrant sufficient certainty to the level that they can be applied to patient care. Without such appraisal, misleading results can be incorporated into patient care, which can lead to inefficient, costly, and possibly harmful care. The Grading of Recommendations, Assessment, Development and Evaluation (GRADE) approach offers a modern framework that can be applied to evaluate the trustworthiness of evidence...
April 2017: Avicenna Journal of Medicine
https://www.readbyqxmd.com/read/28469984/do-not-resuscitate-brain-death-and-organ-transplantation-islamic-perspective
#10
REVIEW
Hassan Chamsi-Pasha, Mohammed Ali Albar
Muslim patients and families are often reluctant to discuss and accept fatal diagnoses and prognoses. In many instances, aggressive therapy is requested by a patient's family, prolonging the life of the patient at all costs. Islamic law permits the withdrawal of futile treatment, including life support, from terminally ill patients allowing death to take its natural course. "Do not resuscitate" is permitted in Islamic law in certain situations. Debate continues about the certainty of brain death criteria within Islamic scholars...
April 2017: Avicenna Journal of Medicine
https://www.readbyqxmd.com/read/28182037/janus-kinase-2-mutations-in-cases-with-bcr-abl-negative-chronic-myeloproliferative-disorders-from-turkey
#11
Ismail Yildiz, Osman Yokuş, Habip Gedik
OBJECTIVE: We aimed to investigate the frequency of Janus kinase 2 (JAK2) mutations in cases with chronic myeloproliferative disorders (CMDs), and the relationship between the presence of JAK2 mutation and leukocytosis and splenomegaly, retrospectively. MATERIALS AND METHODS: Patients, who were diagnosed with BCR-ABL-negative CMDs according to diagnosis criteria of the World Health Organization and followed up at the hematology clinic between 2013 and 2015, were investigated in terms of the frequency of JAK2 mutation in cases with CMDs, and the relationship between the presence of JAK2 mutation and leukocytosis and splenomegaly, retrospectively...
January 2017: Avicenna Journal of Medicine
https://www.readbyqxmd.com/read/28182035/cardiac-emergencies-in-neonates-and-young-infants
#12
REVIEW
Nasib Kabbani, Mohamed S Kabbani, Hayan Al Taweel
Cardiac emergencies in children are not infrequent. Early recognition and management are essential to save life and prevent any comorbidity. The presentation of cardiac emergencies and etiologies is variable depending on the age of child at the time of presentation and type of cardiac lesion. Cyanotic and noncyanotic congenital heart diseases are the main causes in neonates and infants. Acquired heart diseases and dysrhythmia are more common causes for cardiac emergencies in toddler and childhood. In this review, we discuss the most common causes for cardiac emergencies in neonates and young infants highlighting important points in the presentation and management that are essential for early recognition and timely management of infants presenting with these conditions...
January 2017: Avicenna Journal of Medicine
https://www.readbyqxmd.com/read/28182034/topical-vasodilator-response-in-skeletonized-internal-mammary-artery-is-there-really-a-difference
#13
Syed Raza Shah, Syed Arbab Shah, Muhammad Ahmed Jangda, Mohammad Danial Yaqub, Ayesha Altaf Jangda, Maham Khan, Muhammad Asim Khan, Brian Tomkins
AIM OF THE STUDY: Coronary artery bypass graft surgery is the gold standard for the treatment of multivessel and left main coronary artery disease. However, there is considerable debate that whether left internal mammary artery (IMA) should be taken as pedicled or skeletonized. This study was conducted to assess the difference in blood flow after the application of topical vasodilator in skeletonized and pedicled IMA. MATERIALS AND METHODS: In this study, each patient underwent either skeletonized (n = 25) or pedicled IMA harvesting (n = 25)...
January 2017: Avicenna Journal of Medicine
https://www.readbyqxmd.com/read/28182029/very-severe-spinal-muscular-atrophy-type-0
#14
Suleiman Al Dakhoul
This case report describes a rare phenotype of very severe spinal muscular atrophy (SMA) in a newborn who presented with reduced fetal movements in utero and significant respiratory distress at birth. The patient was homozygously deleted for exon 7 and exon 8 of the survival motor neuron gene 1. Very severe SMA should be considered in the differential diagnosis of respiratory distress at birth, and more research should be dedicated to investigate the genetic determinants of its widely variable phenotypes.
January 2017: Avicenna Journal of Medicine
https://www.readbyqxmd.com/read/28182026/prevalence-of-tem-shv-and-ctx-m-beta-lactamase-genes-in-the-urinary-isolates-of-a-tertiary-care-hospital
#15
Trupti Bajpai, M Pandey, M Varma, G S Bhatambare
INTRODUCTION: Extended-spectrum beta-lactamases (ESBLs) are the major cause of resistance to beta-lactam antibiotics such as penicillins, cephalosporins, and monobactams. They are derived from the narrow-spectrum beta-lactamases (TEM-1, TEM-2, or SHV-1) by mutations that alter the amino acid configuration around the enzyme active site. AIM: To determine the prevalence of ESBL (blaTEM, blaCTX-M, and blaSHV) genes among the members of Enterobacteriaceae. METHODOLOGY: The present prospective study was carried out from January 2015 to June 2015 in the Department of Microbiology and Molecular Medicine of a Teaching Tertiary Care Hospital...
January 2017: Avicenna Journal of Medicine
https://www.readbyqxmd.com/read/28182024/impact-of-hospital-and-sociodemographic-factors-on-utilization-of-drug-eluting-stents-in-2011-2012-medicare-cohort
#16
Tushar A Tuliani, Maithili Shenoy, Milind Parikh, Mauricio G Cohen, Cindy Grines, Kenneth Jutzy, Anthony Hilliard
OBJECTIVE: Insurance status is a predictor of drug-eluting stent (DES) usage. Our study sought to determine the effect of hospital and sociodemographic characteristics on utilization of DES in nationwide inpatient discharges with uniform insurance (Medicare). METHODS: We linked data from the 2011 to 2012 Medicare discharges, 2011 Medicare hospital referral region (HRR) report (racial composition of each HRR), American Hospital Association (number of beds, rural/urban location, public/private status, and academic affiliation of hospitals), and American Community Survey 2011 (median income using zip code)...
January 2017: Avicenna Journal of Medicine
https://www.readbyqxmd.com/read/28182021/procedural-moderate-sedation-with-ketamine-in-pediatric-critical-care-unit
#17
Tarek R Hazwani, Hala Al-Alem
OBJECTIVE: To evaluate the safety and efficacy of moderate sedation in the Pediatric Intensive Care Unit (PICU) settings according to moderate sedation protocol using ketamine and midazolam and to determine areas for the improvement in our clinical practice. SETTINGS AND DESIGN: A retrospective study was conducted in the PICU. MATERIALS AND METHODS: Retrospective chart review was performed for patients who had received moderate sedation between January and the end of December 2011 and who are eligible to inclusion criteria...
January 2017: Avicenna Journal of Medicine
https://www.readbyqxmd.com/read/27843802/coronary-ectasia-in-a-man-on-breast-cancer-therapy-presenting-with-acute-coronary-syndrome
#18
Dana C Johnson, Luay Rifai, Parag V Patel
Limited data exist on the association between breast cancer treatments and coronary artery disease anatomy, particularly in males. We describe an unusual case of diffuse coronary ectasia in a man with breast cancer presenting with acute coronary syndrome (ACS). A 66-year-old man with breast cancer on paclitaxel, tamoxifen, and carboplatin chemotherapy regimen, presents with new onset chest pain. Electrocardiogram reveals anterolateral ST-segment depressions and elevated troponin I level. Emergent angiography revealed grossly ectatic coronary arteries with a total thrombotic occlusion of the mid right coronary artery...
October 2016: Avicenna Journal of Medicine
https://www.readbyqxmd.com/read/27843801/interrupted-aortic-arch-with-isolated-persistent-left-superior-vena-cava-in-patient-with-turners-syndrome
#19
M Obadah Kattea, Osama A Smettei, Abdulrahman Kattea, Rami M Abazid
We present a case of 13-year-old female with Turner syndrome (TS), who presented with unexplained lower limbs swelling and ejection systolic murmur at the left second intercostal space. Suspicion of mild aortic coarctation was made by echocardiography. Computed tomography angiography (CTA) showed a complete interruption of the aortic arch (IAA) below the left subclavian artery with persistent left superior vena cava (PLSVC) and absent right SVC, defined as an isolated PLSVC. The patient underwent successful surgical correction after unsuccessful trial of transcatheter stent placement...
October 2016: Avicenna Journal of Medicine
https://www.readbyqxmd.com/read/27843800/left-ventricular-noncompaction-diagnosed-following-graves-disease
#20
Habib Habib, Amer Hawatmeh, Upamanyu Rampal, Fayez Shamoon
Isolated left ventricular noncompaction (LVNC) is a rare genetic cardiomyopathy. Clinical manifestations are variable; patients may present with heart failure symptoms, arrhythmias, and systemic thromboembolism. However, it can also be asymptomatic. When asymptomatic, LVNC can manifest later in life after the onset of another unrelated condition. We report a case of LVNC which was diagnosed following a hyperthyroid state secondary to Graves' disease. The association of LVNC with other noncardiac abnormalities including neurological, hematological, and endocrine abnormalities including hypothyroidism has been described in isolated case reports before...
October 2016: Avicenna Journal of Medicine
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