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Case Reports in Psychiatry

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https://www.readbyqxmd.com/read/27872784/ciprofloxacin-and-clozapine-a-potentially-fatal-but-underappreciated-interaction
#1
Jonathan M Meyer, George Proctor, Michael A Cummings, Laura J Dardashti, Stephen M Stahl
Objective. Clozapine provides a 50%-60% response rate in refractory schizophrenia but has a narrow therapeutic index and is susceptible to pharmacokinetic interactions, particularly with strong inhibitors or inducers of cytochrome P450 (CYP) 1A2. Case Report. We report the case of a 28-year-old nonsmoking female with intellectual disability who was maintained for 3 years on clozapine 100 mg orally twice daily. The patient was treated for presumptive urinary tract infection with ciprofloxacin 500 mg orally twice daily and two days later collapsed and died despite resuscitation efforts...
2016: Case Reports in Psychiatry
https://www.readbyqxmd.com/read/27840761/trichotillomania-as-a-manifestation-of-dementia
#2
Pongsatorn Paholpak, Mario F Mendez
Pathological hair-pulling or trichotillomania, which is commonly associated with anxiety and depression, obsessive-compulsive disorder, and neurodevelopmental disorders, has been rarely associated with dementing illnesses. Investigators have not clarified the neural correlates and treatment of trichotillomania in dementia. We report a patient who developed an early-onset cognitive decline with genetic, cerebrospinal fluid biomarker and structural and functional neuroimaging studies consistent with Alzheimer's disease...
2016: Case Reports in Psychiatry
https://www.readbyqxmd.com/read/27833774/rational-suicide-euthanasia-and-the-very-old-two-case-reports
#3
Anne Pamela Frances Wand, Carmelle Peisah, Brian Draper, Carolyn Jones, Henry Brodaty
Suicide amongst the very old is an important public health issue. Little is known about why older people may express a wish to die or request euthanasia and how such thoughts may intersect with suicide attempts. Palliative care models promote best care as holistic and relieving suffering without hastening death in severely ill patients; but what of those old people who are tired of living and may have chronic symptoms, disability, and reduced quality of life? Two cases of older people who attempted suicide but expressed a preference for euthanasia were it legal are presented in order to illustrate the complexity underlying such requests...
2016: Case Reports in Psychiatry
https://www.readbyqxmd.com/read/27822399/diagnosis-of-dilated-cardiomyopathy-patient-reaction-and-adaptation-case-study-and-review-of-the-literature
#4
Solomis Solomou, Maria Stavrou, Justin Marley
Objective. Heart failure remains a major cause of morbidity and mortality. Given that heart failure generally has a chronic course, it is important to appreciate the impact it can have on the quality of life of patients and also their partners or family carers. Method. Questionnaires were given to a patient newly diagnosed with dilated cardiomyopathy, during his hospital admission, as well as after discharge. The responses are summarised and explored in the discussion section, where we used review of the literature to discuss the implications of a new diagnosis of heart failure...
2016: Case Reports in Psychiatry
https://www.readbyqxmd.com/read/27818825/a-case-of-aripiprazole-induced-tardive-dyskinesia-with-dramatic-evolution
#5
Edwige Heitzmann, Hervé Javelot, Luisa Weiner, Bruno Michel
Aripiprazole is reported to be a good clinical safety profile antipsychotic. However, recent data suggest that the risk of tardive dyskinesia could be higher than initially thought. We report the case of aripiprazole-induced tardive dyskinesia with dramatic evolution in a patient with several risk factors, including older age and exposure to antipsychotic over a period longer than six months. This case and its dramatic evolution, associated with other cases recently published, suggest reconsidering the real risk of tardive dyskinesia associated with aripiprazole, particularly in the elderly...
2016: Case Reports in Psychiatry
https://www.readbyqxmd.com/read/27777807/synthetic-cannabis-overdose-and-withdrawal-in-a-young-adult-a-case-report-commentary-on-regulation-and-review-of-the-literature
#6
John Samaan, Gerardo F Ferrer, Boye Akinyemi, Patricia Junquera, Juan Oms, Rhaisa Dumenigo
Introduction. Marijuana has been used for its psychotropic effects including enhanced relaxation and perceptual alterations. However, the use of synthetic marijuana (SM) leads to more frequent and drastic side effects than the typical use of regular marijuana, owing to the fact that SM has a shorter duration and an earlier peak of action. Despite all the potential adverse health effects associated with SM use, current health policies on SM are very limited. It is believed that the popularity of SM has increased, due to its easy accessibility in the US and lack of detection in typical urine drug screens for THC...
2016: Case Reports in Psychiatry
https://www.readbyqxmd.com/read/27747123/sexual-masochism-disorder-with-asphyxiophilia-a-deadly-yet-underrecognized-disease
#7
Anna Coluccia, Mario Gabbrielli, Giacomo Gualtieri, Fabio Ferretti, Andrea Pozza, Andrea Fagiolini
DSM-5 distinguishes between paraphilias and paraphilic disorders. Paraphilias are defined as atypical, yet not necessarily disordered, sexual practices. Paraphilic disorders are instead diseases, which include distress, impairment in functioning, or entail risk of harm one's self or others. Hence, DSM-5 new approach to paraphilias demedicalizes and destigmatizes unusual sexual behaviors, provided they are not distressing or detrimental to self or others. Asphyxiophilia, a dangerous and potentially deadly form of sexual masochism involving sexual arousal by oxygen deprivation, are clearly described as disorders...
2016: Case Reports in Psychiatry
https://www.readbyqxmd.com/read/27722005/retracted-combined-case-of-blood-injury-injection-phobia-and-social-phobia-behavior-therapy-management-and-effectiveness-through-tilt-test
#8
Case Reports In Psychiatry
[This retracts the article DOI: 10.1155/2012/368039.].
2016: Case Reports in Psychiatry
https://www.readbyqxmd.com/read/27703829/development-of-tinnitus-at-a-low-dose-of-sertraline-clinical-course-and-proposed-mechanisms
#9
Christopher W T Miller
Introduction. Serotonin is involved in filtering of auditory stimuli. Cochlear input is processed through complex interactions between serotonergic, glutamatergic, and GABAergic neurotransmitter systems. Options for treatment of tinnitus include selective serotonin reuptake inhibitors (SSRIs); however in rare instances this symptom may occur as a side effect of this class of medications. Case Presentation. A 50-year-old woman developed bilateral tinnitus after several weeks of being treated with sertraline 50 mg...
2016: Case Reports in Psychiatry
https://www.readbyqxmd.com/read/27688922/delirious-mania-associated-with-autoimmune-gastrothyroidal-syndrome-of-a-mid-life-female-the-role-of-hashimoto-encephalopathy-and-a-3-year-follow-up-including-serum-autoantibody-levels
#10
Udo Bonnet, Claudia Selle, Ralf Kuhlmann
We report the case study of a 57-year-old Caucasian female with steroid-responsive encephalopathy associated with autoimmune thyroiditis (SREAT), commonly termed Hashimoto encephalopathy (HE). This presentation includes one of the longest lasting follow-up studies of HE considering the neuropsychiatric symptoms (here delirium, mania, and EEG-slowing) and their relation to serum autoantibody levels. Antithyroid-peroxidase autoantibodies, the hallmark of autoimmune thyroiditis, were found in the serum and also in the cerebrospinal fluid...
2016: Case Reports in Psychiatry
https://www.readbyqxmd.com/read/27651969/medial-cranial-fossa-meningioma-diagnosed-as-mixed-anxiety-disorder-with-dissociative-symptoms-and-vertigo
#11
Emin Mehmet Ceylan, Bariş Önen Ünsalver, Alper Evrensel
Meningiomas are mostly benign tumors of the meninges that may stay clinically silent or present first with psychiatric symptoms only. We present a case of medial cranial fossa meningioma that was first diagnosed as mixed anxiety disorder with dissociative symptoms and vertigo. In light of the intact neurological and vestibular system examination, our patient's vertigo and depersonalization were firstly addressed as psychosomatic symptoms of the psychiatric syndrome. Despite decreased anxiety and improved mood, dissociative symptoms and vertigo were resistant to treatment which prompted further research yielding a left hemisphere localized meningioma...
2016: Case Reports in Psychiatry
https://www.readbyqxmd.com/read/27597919/two-sudden-and-unexpected-deaths-of-patients-with-schizophrenia-associated-with-intramuscular-injections-of-antipsychotics-and-practice-guidelines-to-limit-the-use-of-high-doses-of-intramuscular-antipsychotics
#12
Nasratullah Wahidi, Katie M Johnson, Allen Brenzel, Jose de Leon
Intravenous haloperidol has been associated with torsades de pointes (TdP). These two sudden deaths were probable adverse drug reactions (ADRs) following intramuscular (IM) antipsychotics. The autopsies described lack of heart pathology and were highly compatible with the possibility of TdP in the absence of risk factors other than the accumulation of antipsychotics with a high serum peak after the last injection, leading to death within hours. The first case was a 27-year-old African-American male with schizophrenia but no medical issues...
2016: Case Reports in Psychiatry
https://www.readbyqxmd.com/read/27597918/successful-treatment-of-suspected-cannabinoid-hyperemesis-syndrome-using-haloperidol-in-the-outpatient-setting
#13
Jennifer L Jones, Karen E Abernathy
Chronic use of cannabis can result in a syndrome of hyperemesis characterized by cyclical vomiting without any other identifiable causes. Cannabinoid hyperemesis syndrome (CHS) is seldom responsive to traditional antiemetic therapies. Despite frequent nausea and vomiting, patients may be reluctant to discontinue use of cannabis. We report a case of severe, refractory CHS with complete resolution of nausea and vomiting after treatment with haloperidol in the outpatient setting. After review of the literature, we believe this is the first reported successful outpatient treatment of CHS and suggests a potential treatment for refractory patients...
2016: Case Reports in Psychiatry
https://www.readbyqxmd.com/read/27559486/effectiveness-of-simple-individual-psychoeducation-for-bipolar-ii-disorder
#14
Yuka Saito-Tanji, Emi Tsujimoto, Reiko Taketani, Ami Yamamoto, Hisae Ono
Several studies have proven the effectiveness of psychoeducation in bipolar II disorder patients; however, simpler psychoeducation is needed in daily medical practice. Therefore, we devised a simple individual psychoeducation program, which involved 20-minute sessions spent reading a textbook aloud in the waiting time before examination. Here, we report a successful case of simple individual psychoeducation with a patient with bipolar II disorder, a 64-year-old woman who had misconceptions surrounding her mood due to 24 years of treatment for depression...
2016: Case Reports in Psychiatry
https://www.readbyqxmd.com/read/27547478/acute-psychosis-as-major-clinical-presentation-of-legionnaires-disease
#15
Ricardo Coentre, Amílcar Silva-Dos-Santos, Miguel Cotrim Talina
We report a case of a 61-year-old woman who presented with acute psychosis as a major manifestation of Legionnaires' disease in the absence of other neuropsychiatric symptoms. Clinical history revealed dry cough and nausea. Observation showed fever and auscultation crackles in the lower lobe of the right lung. Laboratory testing demonstrated elevated C-reactive protein and lung chest radiograph showed patchy peribronchial and right lower lobe consolidation. Soon after admission, she started producing purulent sputum...
2016: Case Reports in Psychiatry
https://www.readbyqxmd.com/read/27525148/clozapine-can-be-the-good-option-in-resistant-mania
#16
S M Yasir Arafat, S M Atikur Rahman, Md Maruful Haque, Mohsin Ali Shah, Sultana Algin, Jhunu Shamsun Nahar
Bipolar mood disorder is a mental disorder with a lifetime prevalence rate of about 1% in the general population and there are still a proportion of individuals who suffer from bipolar mood disorders that are resistant to standard treatment. Reporting clozapine responsive mania that was not responding to two previous consecutive atypical antipsychotics and one typical antipsychotic was aimed at. A 17-year-old male manic patient was admitted into the psychiatry inpatient department and was nonresponsive to Risperidone 12 mg daily for 4 weeks, Olanzapine 30 mg daily for 3 weeks, and Haloperidol 30 mg daily for 3 weeks, along with valproate preparation 1500 mg daily...
2016: Case Reports in Psychiatry
https://www.readbyqxmd.com/read/27516916/valproic-acid-induced-hyperammonemia-in-a-long-time-treated-patient
#17
Rohit Aiyer, Margaret Seide, Robert G Stern
We report a case of a patient who had been on long time valproic acid for treatment of bipolar affective disorder. While being an inpatient, serology ammonia level testing revealed a very high ammonia level despite being asymptomatic. Dual therapy of carnitine and lactulose was provided to the patient for treatment of the hyperammonemia. It should also be noted that, during this treatment, valproic acid was not stopped. Consequently, this case illustrates that patients can present asymptomatically despite very high ammonia levels and hyperammonemia can occur in chronic valproic acid despite not increasing the dose of the medication and psychiatrists do not need to discontinue valproic acid in the presence of elevated levels of ammonia if the patient shows no signs of encephalopathy or delirium...
2016: Case Reports in Psychiatry
https://www.readbyqxmd.com/read/27493822/dandy-walker-malformation-presenting-with-psychological-manifestations
#18
Yasodha Maheshi Rohanachandra, Dulangi Maneksha Amerasinghe Dahanayake, Swarna Wijetunge
Dandy-Walker malformation, which is a congenital malformation of the cerebellum, is documented in literature to be associated with psychotic symptoms, obsessive compulsive symptoms, mood symptoms, hyperactivity, and impulsive behavior. The pathogenesis of psychiatric symptoms in Dandy-Walker malformation is thought to be due to disruption of the corticocerebellar tracts, resulting in what is known as cerebellar cognitive affective syndrome. We present a case of Dandy-Walker malformation presenting with psychiatric symptoms...
2016: Case Reports in Psychiatry
https://www.readbyqxmd.com/read/27493821/generalized-anxiety-disorder-and-hypoglycemia-symptoms-improved-with-diet-modification
#19
Monique Aucoin, Sukriti Bhardwaj
Observational evidence suggests that a relationship may exist between high glycemic index diets and the development of anxiety and depression symptoms; however, as no interventional studies assessing this relationship in a psychiatric population have been completed, the possibility of a causal link is unclear. AB is a 15-year-old female who presented with concerns of generalized anxiety disorder and hypoglycemia symptoms. Her diet consisted primarily of refined carbohydrates. The addition of protein, fat, and fiber to her diet resulted in a substantial decrease in anxiety symptoms as well as a decrease in the frequency and severity of hypoglycemia symptoms...
2016: Case Reports in Psychiatry
https://www.readbyqxmd.com/read/27478672/bilateral-orchidopexy-in-a-hypochondriacal-somatic-symptom-disorder-patient-and-determination-of-fitness-for-bilateral-orchidectomy
#20
A U Nwaopara, Erefagha Leonardo P Allagoa
Introduction. DSM-5 identifies two disorders: somatic symptom disorder and illness anxiety disorder, to replace hypochondriasis in DSM-IV. Patients with both disorders are intensely anxious about the possibility of an undiagnosed illness or devote excessive time and energy to health concerns and are not easily reassured. Both disorders cause considerable distress and life disruption, even at moderate levels. However, hypochondriasis (DSM-IV) is an indication for neither orchidopexy nor orchidectomy. This is the rationale for this report which is the first of its kind to the best of available literature...
2016: Case Reports in Psychiatry
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