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Paediatrics and International Child Health

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https://www.readbyqxmd.com/read/30382004/sudden-unexpected-infant-death-characteristics-in-the-french-region-of-west-provence-alpes-c%C3%A3-te-d-azur
#1
Lucile Tuchtan, Clémence Delteil, Flore Levrat, Juliette Bacquet, Patricia Garcia, Laurence Fayol, Guillaume Gorincour, Christine Zandotti, Nadine Girard, Michel Drancourt, Georges Léonetti, Marie Dominique Piercecchi Marti, Christophe Bartoli
BACKGROUND: Although the incidence of sudden unexpected infant death (SUID) has decreased since the 'Back to Sleep' campaign in English-speaking countries and other preventive campaigns, the circumstances of such deaths remain unclear. AIM: To analyse infant deaths recorded at the referral centre for sudden infant death of the West Provence-Alpes-Côte d'Azur region of France (West PACA) and the forensic medicine department of Marseille University Hospital. METHODS: Information on all SUID cases from 2000 to 2017 was extracted from the referral centre for sudden infant deaths in West PACA and the forensic medicine department of Marseille...
November 1, 2018: Paediatrics and International Child Health
https://www.readbyqxmd.com/read/30382002/thymus-gland-size-during-recovery-from-complicated-severe-acute-malnutrition-a-prospective-study-of-the-role-of-probiotics
#2
Nicolette Nabukeera-Barungi, Benedikte Grenov, Henrik Friis, Betty Lanyero, Hanifa Namusoke, Ezekiel Mupere, Kim F Michaelsen, Christian Mølgaard, Vibeke B Christensen, Maren Johanne Rytter
BACKGROUND: Children with severe acute malnutrition (SAM) are prone to infections due to immune dysfunction including severe thymus atrophy which recovers during nutritional rehabilitation. AIM: To investigate predictors of thymus size recovery, including probiotics during nutritional rehabilitation of children admitted with complicated SAM. METHODS: In this prospective study nested in a randomized controlled trial, children 6-59 months admitted with SAM received standard care and either probiotics or placebo during hospitalization until 8 weeks post-discharge...
November 1, 2018: Paediatrics and International Child Health
https://www.readbyqxmd.com/read/30378470/diagnostic-strategies-for-childhood-tuberculosis-in-the-context-of-primary-care-in-a-high-burden-setting-the-value-of-alternative-sampling-methods
#3
Colleen F Hanrahan, Heather Dansey, Lillian Mutunga, Holly France, Shaheed V Omar, Nazir Ismail, Jean Bassett, Annelies Van Rie
BACKGROUND: Hospital studies have demonstrated the usefulness of alternative sampling strategies to expectorated sputum and new diagnostics for the diagnosis of childhood tuberculosis (TB) but there is limited evidence of how these approaches work in the primary-care setting. AIM: To assess the feasibility and yield of a variety of sample types and diagnostic tests for childhood TB at a primary-care clinic. METHODS: A prospective cohort of children (<10 years) with signs and symptoms of TB was enrolled at a primary-care clinic in Johannesburg, South Africa...
October 31, 2018: Paediatrics and International Child Health
https://www.readbyqxmd.com/read/30378464/correction
#4
(no author information available yet)
No abstract text is available yet for this article.
October 31, 2018: Paediatrics and International Child Health
https://www.readbyqxmd.com/read/30375281/bubble-cpap-devices-for-infants-and-children-in-resource-limited-settings-review-of-the-literature
#5
Alice Won, Daniela Suarez-Rebling, Arianne L Baker, Thomas F Burke, Brett D Nelson
BACKGROUND: Early management of respiratory distress is critical to reducing mortality in infants and children in resource-limited settings. Bubble continuous positive airway pressure (bCPAP) can offer effective and affordable non-invasive respiratory support. OBJECTIVE: To determine the best physical components of bubble CPAP circuits for respiratory support of children in low-resource settings. METHODS: Using PubMed, CINAHL and LILACS, studies of any design in any language published before June 2017 which examined the physical components of bCPAP circuits were identified and reviewed...
October 30, 2018: Paediatrics and International Child Health
https://www.readbyqxmd.com/read/30375272/in-neonates-with-vitamin-d-deficiency-low-lymphocyte-activation-markers-are-risk-factors-for-infection
#6
Mervat A M Youssef, Asmaa M Zahran, Al Montasser Hussien, Khalid I Elsayh, Eman A Askar, Hekmat Saad Farghaly
BACKGROUND: Vitamin D has regulatory effects on different cells of the immune system and low levels are associated with several immune-mediated diseases. AIM: To investigate the association between neonatal 25-hydroxy vitamin D (25-OHD) level and the expression of lymphocyte activation markers (HLA-DR, CD69, CD25, CD45RA) on T-lymphocyte subpopulations and its impact in neonatal infection. METHODS: 25-OHD level was measured in the cord blood of 56 neonates and their mothers using an enzyme immune-assay method...
October 30, 2018: Paediatrics and International Child Health
https://www.readbyqxmd.com/read/30328392/infection-control-and-treatment-guidelines-and-neonatal-mortality-in-a-rural-hospital-in-uganda
#7
Christopher Harris, Harsita Patel, Olivia Corn, Unity Harris, Mary Munyagwa, Anne Greenough
BACKGROUND: The neonatal mortality rate in Uganda has been 24-27/1000 live births for the last 14 years. AIM: To determine the impact on neonatal mortality of the introduction of infection prevention and treatment guidelines in a resource-poor setting. METHODS: A prospective study was undertaken in Kagando Hospital, a rural hospital in Western Uganda of infants live-born in hospital and those admitted from the community or other hospitals between 2013 and 2017...
October 17, 2018: Paediatrics and International Child Health
https://www.readbyqxmd.com/read/30328391/therapeutic-hypothermia-as-standard-care-in-india-a-long-way-to-go
#8
Jogender Kumar, Arushi Yadav
No abstract text is available yet for this article.
October 17, 2018: Paediatrics and International Child Health
https://www.readbyqxmd.com/read/30328390/author-reply-therapeutic-hypothermia-as-standard-care-in-india-a-local-innovation-meets-the-challenge
#9
A Shashidhar, Y N Prashantha, P N Suman Rao
No abstract text is available yet for this article.
October 17, 2018: Paediatrics and International Child Health
https://www.readbyqxmd.com/read/30328387/diagnostic-accuracy-of-the-molteno-adapted-scale-for-developmental-delay-in-south-african-toddlers
#10
Ingrid Honeth, Barbara Laughton, Priscilla E Springer, Mark Fredric Cotton, Chrisma Pretorius
BACKGROUND: There is currently a great need in South Africa for culturally appropriate neurodevelopmental screening measures in order to facilitate early identification of neurodevelopmental problems in children. Neurodevelopmental screening has the potential to decrease the burden at health-care facilities as it is time, resource and cost effective. AIM: To assess the use of the Molteno Adapted Scale (MAS), a locally developed screening measure, to suggest an optimal cut-off score and investigate its accuracy in detecting developmental delays...
October 17, 2018: Paediatrics and International Child Health
https://www.readbyqxmd.com/read/30328385/predictors-of-mortality-in-children-with-nosocomial-bloodstream-infection
#11
Indah K Murni, Trevor Duke, Andrew J Daley, Sharon Kinney, Yati Soenarto
BACKGROUND: Nosocomial bloodstream infection (BSI) is associated with high mortality rates. Evaluating factors to predict mortality is important for prevention and improving clinical outcomes. AIM: To evaluate the clinical predictors of mortality in paediatric nosocomial bloodstream infection. METHODS: A prospective cohort study was conducted from 1 December 2010 until 28 February 2013 in a teaching hospital in Yogyakarta, Indonesia. All patients admitted consecutively to the paediatric ICU (PICU) and paediatric wards after > 48 h of hospitalisation were eligible...
October 17, 2018: Paediatrics and International Child Health
https://www.readbyqxmd.com/read/30295174/acute-chest-syndrome-in-sickle-cell-anaemia-higher-serum-levels-of-interleukin-8-and-highly-sensitive-c-reactive-proteins-are-associated-with-impaired-lung-function
#12
Samuel Ademola Adegoke, Bankole Peter Kuti, Kehinde Oluyori Omole, Olufemi Samuel Smith, Oyeku Akibu Oyelami, Oluwagbemiga Oyewole Adeodu
BACKGROUND: Sickle cell anaemia (SCA) is a chronic inflammatory disorder with multiple organ manifestations including acute and long-term pulmonary dysfunction. AIMS/OBJECTIVES: To assess lung function of children with SCA and determine the possible role of acute chest syndrome (ACS), serum inflammatory cytokines, highly sensitive C-reactive protein (hs-CRP), leucocytes and 25-hydroxyvitamin D on the development of impaired lung function. SUBJECTS AND METHODS: Lung function of 76 children with SCA was determined by spirometer and classified into normal or impaired...
October 8, 2018: Paediatrics and International Child Health
https://www.readbyqxmd.com/read/30284521/disparities-in-rural-vs-urban-achievement-of-millennium-development-goals-in-cambodia-implications-for-current-and-future-child-health
#13
Karen McClure, Jeany K Jun, Casey R Johnson, Philip R Fischer, Lydia Lu, Sophakna Vy, Dale Knutson
BACKGROUND: Cambodia has made significant economic, political, and health advancements with the implementation of the millennium development goals (MDG). Important gaps in child health still exist, however, and accurate assessments of lingering disparities within the country will be essential for meeting the Sustainable Development Goals by 2030. AIM: This investigation hypothesised that child-health improvements in rural areas of Cambodia continue to lag behind urban areas...
October 4, 2018: Paediatrics and International Child Health
https://www.readbyqxmd.com/read/30284512/retropharyngeal-abscess-as-a-paradoxical-reaction-in-a-child-with-multi-drug-resistant-tuberculosis
#14
Lavina Desai, Ira Shah, Manohar Shaan
Paradoxical reactions (PRs) are exaggerated inflammatory responses owing to recovery of cellular immunity following initiation of anti-tuberculous therapy (ATT). The presentation is worsening of pre-existing symptoms or development of new lesions. A 14-year-old girl with multi-drug-resistant tuberculosis developed a recurrent asymptomatic retropharyngeal abscess while on ATT. She required multiple aspirations of the abscess. Xpert MTB/RIF detected Mycobacterium tuberculosis from the aspirate which was resistant to rifampicin; culture was negative...
October 4, 2018: Paediatrics and International Child Health
https://www.readbyqxmd.com/read/30257616/kawasaki-disease-shock-syndrome-and-macrophage-activation-syndrome
#15
Hui-Fang Yang, Hueng-Chuen Fan
No abstract text is available yet for this article.
September 27, 2018: Paediatrics and International Child Health
https://www.readbyqxmd.com/read/30253701/the-link-between-kawasaki-disease-shock-syndrome-and-macrophage-activation-syndrome-in-terms-of-organ-dysfunction-observed-in-children-with-systemic-inflammatory-response-syndrome
#16
Seum-Beom Han, Soo-Young Lee
No abstract text is available yet for this article.
September 26, 2018: Paediatrics and International Child Health
https://www.readbyqxmd.com/read/30191770/lupus-enteritis-as-the-sole-presenting-feature-of-systemic-lupus-erythematosus-case-report-and-review-of-the-literature
#17
Monthira Chowichian, Prapun Aanpreung, Ananya Pongpaibul, Sirirat Charuvanij
Systemic lupus erythematosus (SLE) is a multisystem, autoimmune inflammatory disease which can affect any organ, including the gastrointestinal tract. Lupus enteritis is one of the manifestations of gastrointestinal involvement in SLE patients. However, it is exceedingly rare that lupus enteritis is the sole initial presentation of SLE. A 12-year-old Thai girl who had had recurrent abdominal pain for 2 months with no other signs of SLE on initial presentation is described. A single-balloon enteroscopy demonstrated segmental erythema of the proximal and mid-jejunum...
September 7, 2018: Paediatrics and International Child Health
https://www.readbyqxmd.com/read/30160618/yield-of-meconium-in-non-vigorous-neonates-undergoing-endotracheal-suctioning-and-profile-of-all-neonates-born-through-meconium-stained-amniotic-fluid-a-prospective-observational-study
#18
V R Viraraghavan, Sushma Nangia, B H Prathik, Babu S Madarkar, Deepshika Rani, Arvind Saili
BACKGROUND: Delivery room management of infants born via meconium-stained amniotic fluid (MSAF) is quite controversial. No study has tried to quantify the amount of meconium that can be aspirated from the trachea of a non-vigorous neonate born through MSAF. AIMS: To study the yield of meconium in non-vigorous neonates born through MSAF undergoing endotracheal (ET) suctioning. METHODS: This was a prospective observational study conducted from 1 March 2015 to 31 October 2015...
August 30, 2018: Paediatrics and International Child Health
https://www.readbyqxmd.com/read/30160613/corrigendum
#19
(no author information available yet)
No abstract text is available yet for this article.
August 30, 2018: Paediatrics and International Child Health
https://www.readbyqxmd.com/read/30132736/parasitic-infections-of-the-gut-in-children
#20
Kapula Chifunda, Paul Kelly
Parasitic infections of the gut have major implications for child health, but many questions remain unanswered. Protozoal parasites, especially cryptosporidiosis and giardiasis, cause diarrhoea and contribute to impaired growth, neurocognitive development and mortality. Entamoeba histolytica causes dysentery and may have more subtle effects on child growth. Helminth infections are mostly asymptomatic, and untargeted mass deworming has not been shown to be beneficial. However, children with heavy infections certainly benefit from antihelminthic treatment...
August 22, 2018: Paediatrics and International Child Health
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