Vadim Osadchiy, Carlos Munoz-Lopez, Tommy Jiang, Bryan D Naelitz, Neel Parekh, Sarah C Vij, Jesse N Mills, Scott D Lundy, Sriram V Eleswarapu
In men with impaired semen parameters, empiric medical therapies such as clomiphene citrate, a selective estrogen receptor modulator (SERM), and anastrozole, a selective aromatase inhibitor, are often employed. The effects of jointly administering these agents on semen parameters are not well understood. Here, we describe the findings of our multi-center, retrospective cohort study of men with idiopathic primary or secondary infertility. Twenty-one men were treated with combination therapy (anastrozole and clomiphene) and 69 men were treated with monotherapy (anastrozole)...
February 29, 2024: Translational Andrology and Urology