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Case Reports in Ophthalmological Medicine

Jaclyn L Kovach
This report describes the first case of extensive macular atrophy with pseudodrusen (EMAP) imaged with optical coherence tomography angiography (OCTA). A 58-year-old Caucasian man presented with decreased central vision in both eyes. Fundus examination showed large areas of macular atrophy centered on the fovea surrounded by diffuse reticular pseudodrusen. Spectral domain OCT (SDOCT) revealed outer retinal and choriocapillaris atrophy. OCTA demonstrated marked absence of choriocapillaris flow. Extensive macular atrophy with pseudodrusen is a rare clinical entity and a new extreme phenotype of macular degenerations that could shed more light on the role of pseudodrusen and choriocapillaris compromise in the pathogenesis of AMD...
2018: Case Reports in Ophthalmological Medicine
A Moramarco, M Marenco, M La Cava, A Lambiase
Plasmablastic lymphoma (PBL) is a malignant, rare, and aggressive form of non-Hodgkin's lymphoma with poor response to treatment that most commonly involves the oral mucosa of immunodeficient patients. The orbit might be primarily or secondarily involved; on the other hand other pathological conditions, i.e., fungal infections, may localize in the orbit in both immunocompromised patients and drug user, which might have similar radiological features. We describe the clinical, radiological, and pathological features of an orbital plasmablastic lymphoma (PBL) in an immunocompromised HIV positive drug user patient...
2018: Case Reports in Ophthalmological Medicine
Daniel D Kim, Ghassan Ghorayeb
Acute posterior multifocal placoid pigment epitheliopathy (APMPEE) is a chorioretinal inflammatory disease of unknown origin. Patients usually present with a rapid loss of central/paracentral vision over the course of a week in both eyes. The fundus exhibits rapid appearance of multiple deep subretinal yellow-white, flat lesions at the RPE/choriocapillaris level. This in turn causes changes of both the ellipsoid zone and RPE which can result in permanent central vision loss. The pathogenesis is controversial but is associated with a recent viral illness and can involve the central nervous system with concern for cerebral vasculitis...
2018: Case Reports in Ophthalmological Medicine
Thomas Stahnke, Andreas Erbersdobler, Steffi Knappe, Rudolf F Guthoff, Ngoy J Kilangalanga
An early developmental lack of the optic vesicle can result in congenital anophthalmia, defined as a complete absence of the eye, which can be distinguished from congenital microphthalmos, where ocular rudiments are present. Here, a rare pediatric case of congenital clinical anophthalmos with orbital cyst in the left orbit is reported. The patient was a 14-month-old girl with no other congenital defects who underwent surgical and prothetic management in St. Joseph's Hospital Kinshasa, Democratic Republic of the Congo (DRC)...
2018: Case Reports in Ophthalmological Medicine
Jia Jeane Ngai, Ka Lung Chong, Shelina Oli Mohamed
Introduction: To report an unusual case of CMV retinitis in Primary Immune Deficiency Disease (PIDD). Case Report: 13-year-old child with combined T and B cell deficiencies was diagnosed of bilateral zone 1 CMV retinitis. Intravitreal injections were unable to be given in a regular and timely manner under general anaesthesia due to her underlying systemic disease. The child was treated with intravenous ganciclovir for 8 weeks until eventual resolution of the retinitis...
2018: Case Reports in Ophthalmological Medicine
Lucía Jáñez-García, Enrique Mencía-Gutiérrez, Esperanza Gutiérrez-Díaz, Luis F Moreno-García-Rubio, Laura Zarratea-Herreros, Álvaro Bengoa-González, Silvia Pérez-Trigo
Penetrating injuries of the cranium are relatively uncommon, only 0.4% of all head injuries. In patients with disturbed conscious level, an extensive examination should be performed in the emergency unit to rule out transorbital penetrating brain injury. A 25-year-old male was attacked with a dagger. He presented with ethylic intoxication and the physical examination demonstrated a small skin injury on the lateral canthus of the left eye with a large periocular hematoma which prevented eyelid opening. Cranial CT scan showed a metallic intraorbital foreign body consisting of a fragment of a dagger which perforated the eyeball, and penetrated through the superomedial wall of the orbit into the anterior cranial fossa...
2018: Case Reports in Ophthalmological Medicine
Elcin Suren, Melih Akidan, Muhammet Kazim Erol, Devrim Toslak
Purpose: The purpose of this report is to present a case who had spontaneous macular hole closure after Nd:YAG laser membranotomy applied to premacular haemorrhage associated with Valsalva retinopathy. Methods: Case report. Results: A 19-year-old young male patient presented to our clinic with sudden vision loss in his right eye, which had occurred 2 weeks before, following push-up and sit-up exercise. The patient was found to have premacular haemorrhage associated with Valsalva retinopathy...
2018: Case Reports in Ophthalmological Medicine
Emilio Campos, Piera Versura, Giuseppe Giannaccare, Adriana Terzi, Silvia Bisti, Stefano Di Marco, Marina Buzzi
Purpose: To report data which happened to be observed in two glaucoma patients treated with Cord Blood Serum (CBS) eye drops. Design: A case report and retrospective data analysis. Methods: CBS topical eye drops, characterized in advance for growth factors (GFs) content, were administered for two months with the aim to relieve their subjective symptoms, in two patients who had referred ocular surface discomfort, although in absence of any sign of keratopathy...
2018: Case Reports in Ophthalmological Medicine
Laura Hernandez-Moreno, Natacha Moreno Perdomo, Tomas S Aleman, Karthikeyan Baskaran, Antonio Filipe Macedo
The purpose of this report is to describe a case of bilateral foveal hypoplasia in the absence of other ophthalmological or systemic manifestations. We characterize the case of a 9-year-old Caucasian male who underwent full ophthalmologic examination, including functional measures of vision and structural measurements of the eye. Best corrected visual acuity was 0.50 logMAR in the right eye and 0.40 logMAR in the left eye. Ophthalmoscopy revealed a lack of foveal reflex that was further investigated. Optical coherence tomography (OCT) confirmed the absence of foveal depression (pit)...
2018: Case Reports in Ophthalmological Medicine
A Saad, S O Salceanu, K Oswal, A Aboushrkh, D Hamada
Purpose: To demonstrate the importance of subretinal biopsy to reach a diagnosis when vitreous biopsy is negative or inconclusive. Methods: A 54-year-old Caucasian gentleman presented with bilateral anterior uveitis at JCUH. He initially responded to topical steroids and dilating agents. Subsequently he developed bilateral panuveitis and cataract with poor response to treatment. Detailed workup had been done to rule out infectious etiology. A suspicion of lymphoma was considered and vitreous biopsy sample was taken from one eye, which was inconclusive...
2018: Case Reports in Ophthalmological Medicine
Dev R Sahni, Michael Wallace, Mansi Kanhere, Hind Al Saif, Natario Couser
Turner syndrome is a common sex chromosome disorder affecting females. The disorder is caused by a partial loss, complete absence, or structural abnormality of one X chromosome. The clinical presentation is broad and ranges from the classic phenotype to minimal clinical manifestations. Ocular abnormalities associated with the syndrome are common. Reports describing abnormal eye features in individuals with Turner syndrome generally involve refractive errors (myopia or hyperopia), strabismus, and external or anterior segment abnormalities including hypertelorism, epicanthal folds, and ptosis...
2018: Case Reports in Ophthalmological Medicine
Aakriti Garg, Joaquin De Rojas, Priya Mathews, Albert Hazan, James Lin, Danielle Trief, Leejee H Suh
We report two cases of peripheral ulcerative keratitis (PUK) imaged with anterior segment optical coherence tomography (AS-OCT). The first patient had prolonged nonsteroidal anti-inflammatory drug use, while the second had inflammatory arthritis by laboratory findings without any systemic findings as well as possible concurrent tuberculosis. In both patients, AS-OCT demonstrated corneal thinning at the onset of the disease with improvement six months after initiation of intensive medical therapy. Our cases highlight the need for a multidisciplinary approach and careful monitoring in PUK cases, especially with objective measures such as corneal thickness assessed with AS-OCT...
2018: Case Reports in Ophthalmological Medicine
Masaki Nakamura, Koji Komatsu, Satoshi Katagiri, Takaaki Hayashi, Tadashi Nakano
Purpose: To report the clinical course of solar retinopathy after steroid therapy. Case Presentation: A 45-year-old male gazed at the sun and noticed bilateral central scotoma and decreased vision after the episode. After 7 weeks from onset, ophthalmic examinations were firstly performed. Decimal best corrected visual acuity (BCVA) was decreased to 0.8 and 0.7 in the right and left eyes. Funduscopy showed a tiny, yellowish spot in the fovea bilaterally. Corresponding to the lesion, optical coherence tomography (OCT) images showed an elevated and blurred ellipsoid zone and loss of the interdigitation zone...
2018: Case Reports in Ophthalmological Medicine
Stephen G Schwartz, Harry W Flynn, Andrzej Grzybowski, Avinash Pathengay, Ingrid U Scott
No abstract text is available yet for this article.
2018: Case Reports in Ophthalmological Medicine
Yasin Sakir Goker, Kemal Tekin, Cemile Ucgul Atilgan, Pinar Kosekahya, Pelin Yilmazbas
A 27-year-old male was presented with a sudden onset of visual loss in his right eye. A secondary care center referred the patient with fundus photographs which were screened 4 days before and after the Nd: YAG laser hyaloidotomy treatment. Snellen acuity was 10/10 in both eyes. Fundus examinations revealed a retinal pigment epithelium (RPE) alteration at the margin of the inferior temporal arterial vascular arcade in the right eye and resolved preretinal and subretinal hemorrhages were seen in the macula. A diagnosis of Valsalva retinopathy was made based on the history and the treatment photographs of Nd:YAG laser hyaloidotomy...
2018: Case Reports in Ophthalmological Medicine
Chu Luan Nguyen, Tony S Chen, Khoi Tran, James E H Smith, Noni Lewis
Purpose: To report the efficacy of subconjunctival triamcinolone (Kenalog A-40, Alcon) and bevacizumab (Avastin, Genentech) injections in fraternal twins with blepharokeratoconjunctivitis (BKC) causing progressive, bilateral corneal neovascularization and scarring. Methods: In this retrospective observational case series, two three-year-old male twins with BKC had presented with bilateral red eyes, photophobia, and frequent blinking. Examination of each child showed bilateral deep stromal and superficial corneal neovascularization, corneal infiltrates, multiple follicles on the palpebral conjunctiva bilaterally with blepharitis, and thick turbid sebum expressed from the Meibomian glands...
2018: Case Reports in Ophthalmological Medicine
Aya Kodama-Takahashi, Koji Sugioka, Tomoko Sato, Koichi Nishida, Keiichi Aomatsu, Masahiko Fukuda, Yoshikazu Shimomura
Purpose: To report a case of persistent corneal epithelial defect that had occurred after a trigeminal nerve block. Case Presentation: A 75-year-old female had suffered from postherpetic neuralgia for 8 years. She underwent Gasserian ganglion block surgery and noticed declining visual acuity in the right eye on the following day. She presented with severe hyperemia and corneal epithelial defects in the right eye and experienced remarkable reduction of sensitivity in the right cornea...
2018: Case Reports in Ophthalmological Medicine
Rajya L Gurung
Valsalva retinopathy is a common condition but retinal holes secondary to Valsalva retinopathy are rarely reported. The author believes this to be the first report to describe multiple retinal holes after hyaloidotomy for Valsalva retinopathy.
2018: Case Reports in Ophthalmological Medicine
Hacer Isildak, Stephen G Schwartz, Harry W Flynn
Intravitreal injections of antivascular endothelial growth factor (anti-VEGF) agents have been reported to occasionally produce a therapeutic effect in the uninjected fellow eye. Here, three patients with bilateral neovascular age-related macular degeneration are presented. In all three patients, unilateral anti-VEGF injection resulted in bilateral reduction of macular thickness as measured by spectral domain optical coherence tomography.
2018: Case Reports in Ophthalmological Medicine
Mayuresh Naik, Anuj Mehta, Neha Mehrotra, Anil Solanki
A 2-year-old male child presented with a painless progressive mass in the inferolateral aspect of right orbit of three-month duration. Differential leucocyte count revealed raised eosinophil count (13%). On radiological examination, CT scan showed 25 × 27 mm round well-defined smooth-outlined homogenously enhancing extraconal mass arising from the zygomatic bone at the inferotemporal periorbital area of right orbit with bone erosion. Histopathological examination of the incision biopsy revealed characteristic Langerhans cells and immunohistochemical studies were positive for S-100 protein and adenosine deaminase...
2018: Case Reports in Ophthalmological Medicine
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