Patricia Ondine Lucaciu, Călin Cosmin Repciuc, Ioana A Matei, Nicodim I Fiț, Sanda Andrei, Raluca Marica, Bianca Nausica Petrescu, Bogdan Crișan, Ovidiu Aghiorghiesei, Ioana Codruța Mirică, Dragoș Apostu, Codruța Saroși, Florin Onișor, Evelyn Vanea, Simina Angela Lăcrimioara Iușan, Giorgiana Corina Mureșan, Ana-Maria Condor, Emilia Oprița, Luciana-Mădălina Gherman
The aim of this research was to validate the use of a gentamicin (GEN) and nano-hydroxiapatite (nHAP)-loaded polycaprolactone nanostructured membrane (NM) as an innovative, highly efficient, low-cost treatment for periodontitis. We conducted an in vivo study on Wistar rats, in which we induced periodontitis by placing silk ligatures around the first right and left upper molars. The subjects were divided into three groups; the first group received no periodontal treatment, the second group received open flap debridement, and the third group received open flap debridement, together with the positioning of the GEN and nHAP-loaded nanostructured membrane as a treatment...
February 26, 2024: Membranes