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Radiation Oncology Journal

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https://www.readbyqxmd.com/read/29262672/dosimetric-comparison-between-modulated-arc-therapy-and-static-intensity-modulated-radiotherapy-in-thoracic-esophageal-cancer-a-single-institutional-experience
#1
Kyu Hye Choi, Jina Kim, Sea-Won Lee, Young-Nam Kang, HongSeok Jang
Purpose: The objective of this study was to compare dosimetric characteristics of three-dimensional conformal radiotherapy (3D-CRT) and two types of intensity-modulated radiotherapy (IMRT) which are step-and-shoot intensity modulated radiotherapy (s-IMRT) and modulated arc therapy (mARC) for thoracic esophageal cancer and analyze whether IMRT could reduce organ-at-risk (OAR) dose. Materials and Methods: We performed 3D-CRT, s-IMRT, and mARC planning for ten patients with thoracic esophageal cancer...
December 23, 2017: Radiation Oncology Journal
https://www.readbyqxmd.com/read/29262671/prophylactic-extended-field-irradiation-with-concurrent-chemotherapy-for-pelvic-lymph-node-positive-cervical-cancer
#2
Jinju Oh, Ki Ho Seol, Hyun Joo Lee, Youn Seok Choi, Ji Y Park, Jin Young Bae
Purpose: This study aimed to evaluate whether prophylactic extended-field pelvic radiotherapy (EF-PRT) yields better results than standard whole pelvic radiotherapy (WPRT) in patients with pelvic lymph node-positive cervical cancer treated with concurrent chemoradiotherapy (CCRT). Materials and Methods: A total of 126 cases of stage IB-IVA cervical cancer that had pelvic lymph node involvement in magnetic resonance imaging and were treated with CCRT between 2000 and 2016 were reviewed...
December 23, 2017: Radiation Oncology Journal
https://www.readbyqxmd.com/read/29249117/patterns-of-initial-failure-after-resection-for-gallbladder-cancer-implications-for-adjuvant-radiotherapy
#3
Tae Gyu Kim
Purpose: This study sought to identify potential candidates for adjuvant radiotherapy and patterns of regional failure in patients who underwent curative-intent surgery for gallbladder cancer. Materials and Methods: Records for 70 patients with gallbladder cancer who underwent curative resection at a single institution between 2000 and 2016 were analysed retrospectively. No patients received adjuvant radiotherapy. Initial patterns of failure were evaluated. Regional recurrence was categorized according to the definitions of lymph node stations suggested by the Japanese Society of Hepato-Biliary-Pancreatic Surgery...
December 20, 2017: Radiation Oncology Journal
https://www.readbyqxmd.com/read/29232805/value-of-imaging-study-in-predicting-pelvic-lymph-node-metastases-of-uterine-cervical-cancer
#4
Wonguen Jung, Kyung Ran Park, Kyung-Ja Lee, Kyubo Kim, Jihae Lee, Songmi Jeong, Yi-Jun Kim, Jiyoung Kim, Hai-Jeon Yoon, Byung-Chul Kang, Hae Soo Koo, Sun Hee Sung, Min-Sun Cho, Sanghui Park
Purpose: To evaluate the diagnostic accuracy of computed tomography (CT), magnetic resonance imaging (MRI), and positron emission tomography/computed tomography (PET/CT) in predicting pelvic lymph node (LN) metastases in patients with cervical cancer. Materials and Methods: From January 2009 to March 2015, 114 patients with FIGO stage IA1-IIB uterine cervical cancer who underwent hysterectomy with pelvic lymphadenectomy and took CT, MRI, and PET/CT before surgery were enrolled in this study...
December 15, 2017: Radiation Oncology Journal
https://www.readbyqxmd.com/read/29232804/lymphovascular-invasion-as-a-negative-prognostic-factor-for-triple-negative-breast-cancer-after-surgery
#5
Ki Jung Ahn, Jisun Park, Yunseon Choi
Purpose: This study aimed to evaluate the prognostic effects of lymphovascular invasion (LVI) in triple-negative breast cancer (TNBC) patients who underwent surgical resection. Materials and Methods: A total of 63 non-metastatic TNBC patients who underwent surgical resection were retrospectively investigated from 2007 to 2016 in Inje University Busan Paik Hospital. Pathological tests revealed that 12 patients (19.0%) had LVI. Approximately 61.9% (n = 39) of the patients' samples stained positive for p53...
December 15, 2017: Radiation Oncology Journal
https://www.readbyqxmd.com/read/29207866/interobserver-variation-in-target-volume-for-salvage-radiotherapy-in-recurrent-prostate-cancer-patients-after-radical-prostatectomy-using-ct-versus-combined-ct-and-mri-a-multicenter-study-krog-13-11
#6
Eonju Lee, Won Park, Sung Hwan Ahn, Jae Ho Cho, Jin Hee Kim, Kwan Ho Cho, Young Min Choi, Jae-Sung Kim, Jin Ho Kim, Hong-Seok Jang, Young-Seok Kim, Taek-Keun Nam
Purpose: To investigate interobserver variation in target volume delineations for prostate cancer salvage radiotherapy using planning computed tomography (CT) versus combined planning CT and magnetic resonance imaging (MRI). Materials and Methods: Ten radiation oncologists independently delineated a target volume on the planning CT scans of five cases with different pathological status after radical prostatectomy. Two weeks later, this was repeated with the addition of planning MRI...
December 15, 2017: Radiation Oncology Journal
https://www.readbyqxmd.com/read/29207865/prognostic-value-of-nodal-suvmax-of-18f-fdg-pet-ct-in-nasopharyngeal-carcinoma-treated-with-intensity-modulated-radiotherapy
#7
So Jung Lee, Chul-Seoung Kay, Yeon-Sil Kim, Seok Hyun Son, Myungsoo Kim, Sea-Won Lee, Hye Jin Kang
Purpose: To investigate the predictive role of maximum standardized uptake value (SUVmax) of 2-[18F]fluoro-2-deoxy-D-glucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) in nasopharyngeal cancer patients treated with intensitymodulated radiotherapy (IMRT). Materials and Methods: Between October 2006 and April 2016, 53 patients were treated with IMRT in two institutions and their PET/CT at the time of diagnosis was reviewed. The SUVmax of their nasopharyngeal lesions and metastatic lymph nodes (LN) was recorded...
December 15, 2017: Radiation Oncology Journal
https://www.readbyqxmd.com/read/29207864/long-term-cosmesis-following-a-novel-schedule-of-accelerated-partial-breast-radiation-in-selected-early-stage-breast-cancer-result-of-a-prospective-clinical-trial
#8
Mutlay Sayan, Daphne Hard, Karen Wilson, Carl Nelson, Havaleh Gagne, Deborah Rubin, Ruth Heimann
Purpose: There is controversy regarding the cosmetic outcome after accelerated partial breast radiation (APBR). We report the cosmetic outcome from a single-arm prospective clinical trial of APBR delivered using intensity-modulated radiation therapy (IMRT) in elderly patients with stage I breast cancer (BC), using a novel fractionation schedule. Materials and Methods: Forty-two patients aged ≥65, with Stage I BC who underwent breast-conserving surgery were enrolled in a phase I/II study evaluating a 2-week course of APBR...
December 15, 2017: Radiation Oncology Journal
https://www.readbyqxmd.com/read/29325396/treatment-results-of-radiotherapy-following-chop-or-r-chop-in-limited-stage-head-and-neck-diffuse-large-b-cell-lymphoma-a-single-institutional-experience
#9
Jae-Uk Jeong, Woong-Ki Chung, Taek-Keun Nam, Deok-Hwan Yang, Sung-Ja Ahn, Ju-Young Song, Mee Sun Yoon, Yong-Hyeob Kim
PURPOSE: This study evaluated outcomes of radiotherapy (RT) after chemotherapy in limited-stage head-and-neck diffuse large B-cell lymphoma (DLBCL). MATERIALS AND METHODS: Eighty patients who were treated for limited-stage head-and-neck DLBCL with CHOP (n = 43) or R-CHOP (n = 37), were analyzed. After chemotherapy, RT was administered to the extended field (n = 60) or the involved field (n = 16), or the involved site (n = 4). The median dose of RT ranged from 36 Gy in case of those with a complete response, to 45-60 Gy in those with a partial response...
December 2017: Radiation Oncology Journal
https://www.readbyqxmd.com/read/29325395/controversial-issues-in-radiotherapy-for-rectal-cancer-a-systematic-review
#10
REVIEW
Jong Hoon Kim
The role of radiotherapy (RT) as an adjuvant to surgical options in the treatment of locally advanced rectal cancer has been established as it reduces local recurrence when combined with surgical resection and enhances survival when used in multidisciplinary treatment. However, many issues need to be addressed; some of these can render RT unnecessary, whereas others can reveal a new role of RT in rectal cancer. This review will discuss not only the basic role of RT but also the associated but controversial issues in detail in an attempt to find answers and determine future directions for the next decade...
December 2017: Radiation Oncology Journal
https://www.readbyqxmd.com/read/29325394/correction-adverse-effect-of-excess-body-weight-on-survival-in-cervical-cancer-patients-after-surgery-and-radiotherapy
#11
Yunseon Choi, Ki Jung Ahn, Sung Kwang Park, Heunglae Cho, Ji Young Lee
[This corrects the article on p. 48 in vol. 35.].
December 2017: Radiation Oncology Journal
https://www.readbyqxmd.com/read/28893059/dosimetric-advantages-and-clinical-outcomes-of-simultaneous-integrated-boost-intensity-modulated-radiotherapy-for-anal-squamous-cell-carcinoma
#12
Katsuyuki Sakanaka, Satoshi Itasaka, Yuichi Ishida, Kota Fujii, Takahiro Horimatsu, Takashi Mizowaki, Yoshiharu Sakai, Masahiro Hiraoka
Purpose: The purpose of this study was to explore the dosimetric difference between simultaneous integrated boost intensity-modulated radiotherapy (SIB-IMRT) and three-dimensional conformal radiotherapy (3DCRT), and the clinical outcomes of anal squamous cell carcinoma (ASCC) chemoradiotherapy featuring SIB-IMRT. Materials and Methods: This study included ten patients with ASCC who underwent chemoradiotherapy using SIB-IMRT with 5-fluorouracil and mitomycin C. SIB-IMRT delivered 54 Gy to each primary tumor plus metastatic lymph nodes and 45 Gy to regional lymph nodes, in 30 fractions...
September 15, 2017: Radiation Oncology Journal
https://www.readbyqxmd.com/read/28881504/low-dose-radiation-therapy-for-massive-chylous-leakage-after-subtotal-gastrectomy
#13
Sang-Won Kim, Jung Hoon Kim
Massive chylous leakage is a rare postoperative complication that can prolong hospital stay and cause secondary morbidities. Conservative management strategies are the treatment of choice; however, radiation therapy (RT) can be used as an alternative for cases that are refractory to conservative treatment. Herein, we report a 69-year-old female patient who suffered from massive chylous leakage after subtotal gastrectomy. Due to persistent massive chylous leakage, she was scheduled to undergo low-dose RT. Radiation was delivered with a daily dose of 1 Gy, using an anterior-posterior and posterior-anterior beam arrangement...
September 15, 2017: Radiation Oncology Journal
https://www.readbyqxmd.com/read/29037027/refining-prognostic-stratification-of-human-papillomavirus-related-oropharyngeal-squamous-cell-carcinoma-different-prognosis-between-t1-and-t2
#14
Sumin Lee, Sang-Wook Lee, Sunmin Park, Sang Min Yoon, Jin-Hong Park, Si Yeol Song, Seung Do Ahn, Jong Hoon Kim, Eun Kyung Choi, Su Ssan Kim, Jinhong Jung, Young Seok Kim
PURPOSE: To validate the 8th edition of the American Joint Committee on Cancer/Union for International Cancer Control (AJCC/UICC) TNM staging system for human papillomavirus (HPV)-related oropharyngeal squamous cell carcinoma (OPSCC) and investigate whether a modified classification better reflects the prognosis. MATERIALS AND METHODS: Medical records of patients diagnosed with non-metastatic HPV-related OPSCC between 2010 and 2016 at a single institution were retrospectively reviewed...
September 2017: Radiation Oncology Journal
https://www.readbyqxmd.com/read/29037026/treatment-outcomes-of-extended-field-radiation-therapy-for-thoracic-superficial-esophageal-cancer
#15
Doo Yeul Lee, Sung Ho Moon, Kwan Ho Cho, Tae Hyun Kim, Moon Soo Kim, Jong Yeul Lee, Yang-Gun Suh
PURPOSE: To evaluate the efficacy and safety of extended-field radiation therapy for patients with thoracic superficial esophageal cancer (SEC). MATERIALS AND METHODS: From May 2007 to October 2016, a total of 24 patients with thoracic SEC (T1a and T1b) who underwent definitive radiotherapy and were analyzed retrospectively. The median total radiotherapy dose was 64 Gy (range, 54 to 66 Gy) in conventional fractionation. All 24 patients received radiotherapy to whole thoracic esophagus and 23 patients received elective nodal irradiation...
September 2017: Radiation Oncology Journal
https://www.readbyqxmd.com/read/29037025/gross-tumor-volume-dependency-on-phase-sorting-methods-of-four-dimensional-computed-tomography-images-for-lung-cancer
#16
Soo Yong Lee, Sangwook Lim, Sun Young Ma, Jesang Yu
PURPOSE: To see the gross tumor volume (GTV) dependency according to the phase selection and reconstruction methods, we measured and analyzed the changes of tumor volume and motion at each phase in 20 cases with lung cancer patients who underwent image-guided radiotherapy. MATERIALS AND METHODS: We retrospectively analyzed four-dimensional computed tomography (4D-CT) images in 20 cases of 19 patients who underwent image-guided radiotherapy. The 4D-CT images were reconstructed by the maximum intensity projection (MIP) and the minimum intensity projection (Min-IP) method after sorting phase as 40%-60%, 30%-70%, and 0%-90%...
September 2017: Radiation Oncology Journal
https://www.readbyqxmd.com/read/29037024/treatment-outcome-and-risk-analysis-for-cataract-after-radiotherapy-of-localized-ocular-adnexal-mucosa-associated-lymphoid-tissue-malt-lymphoma
#17
Hee Hyun Park, Sea-Won Lee, Soo Yoon Sung, Byung Ock Choi
PURPOSE: We retrospectively reviewed the results of radiotherapy for localized ocular adnexal MALT lymphoma (OAML) to investigate the risk factors of cataract. METHODS: Sixty-seven patients with stage IE OAML treated with radiotherapy at Seoul St. Mary's Hospital from 2001 to 2016 were included. Median treatment dose was 30 Gy. Lens protection was done in 52 (76%) patients. Radiation therapy (RT) extent was as follows: superficial (82.1%), tumor mass (4.5%), and entire orbital socket (13...
September 2017: Radiation Oncology Journal
https://www.readbyqxmd.com/read/29037023/simultaneous-integrated-boost-intensity-modulated-radiotherapy-versus-3-dimensional-conformal-radiotherapy-in-preoperative-concurrent-chemoradiotherapy-for-locally-advanced-rectal-cancer
#18
Bong Kyung Bae, Min Kyu Kang, Jae-Chul Kim, Mi Young Kim, Gyu-Seog Choi, Jong Gwang Kim, Byung Woog Kang, Hye Jin Kim, Soo Yeun Park
PURPOSE: To evaluate the feasibility of simultaneous integrated boost intensity-modulated radiotherapy (SIB-IMRT) for preoperative concurrent chemoradiotherapy (PCRT) in locally advanced rectal cancer (LARC), by comparing with 3-dimensional conformal radiotherapy (3D-CRT). MATERIALS AND METHODS: Patients who were treated with PCRT for LARC from 2015 January to 2016 December were retrospectively enrolled. Total doses of 45 Gy to 50.4 Gy with 3D-CRT or SIB-IMRT were administered concomitantly with 5-fluorouracil plus leucovorin or capecitabine...
September 2017: Radiation Oncology Journal
https://www.readbyqxmd.com/read/29037022/radiation-recall-dermatitis-triggered-by-sorafenib-after-radiation-therapy-for-hepatocellular-carcinoma
#19
Gwi Eon Kim, Hee-Sung Song, Ki Jung Ahn, Young Suk Kim
Sorafenib is widely used for unresectable and metastatic hepatocellular carcinomas. Radiation recall dermatitis (RRD) is an acute inflammatory reaction confined to previously irradiated skin that occurs after the administration of certain drugs. RRD after sorafenib treatment is rare; five cases have been reported thus far. We describe a 44-year-old man irradiated for chest wall bone metastasis from hepatocellular carcinoma. Eight days after radiotherapy completion, systemic therapy for metastatic hepatocellular carcinoma was initiated with sorafenib treatment...
September 2017: Radiation Oncology Journal
https://www.readbyqxmd.com/read/29037021/multimodal-therapy-for-locally-advanced-prostate-cancer-the-roles-of-radiotherapy-androgen-deprivation-therapy-and-their-combination
#20
REVIEW
Sung Uk Lee, Kwan Ho Cho
Locally advanced prostate cancer (LAPC) is defined as histologically proven T3-4 prostatic adenocarcinoma. In this review, we define the individual roles of radiotherapy (RT), short-term (ST-) and long-term (LT-) androgen deprivation therapy (ADT), and their combination in multimodal therapy for LAPC. Despite limitations in comparing the clinical outcomes among published papers, in the present study, a trend of 10-year clinical outcomes was roughly estimated by calculating the average rates weighted by the cohort number...
September 2017: Radiation Oncology Journal
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