journal
MENU ▼
Read by QxMD icon Read
search

Journal of Comparative Effectiveness Research

journal
https://www.readbyqxmd.com/read/29775086/healthcare-utilization-and-costs-of-multiple-sclerosis-patients-in-the-netherlands-a-healthcare-claims-database-study
#1
Servaas Buijs, Marieke Krol, Gert de Voer
AIM: To investigate the incidence and prevalence and healthcare costs of multiple sclerosis (MS) in the Netherlands by using healthcare claims data. MATERIALS & METHODS: A claims database was analyzed including 26% of the Dutch population. RESULTS: Average prevalence of MS in the Netherlands was 88 per 100,000 inhabitants (males 48, 127 females) and incidence nine per 100,000. Yearly per patient medication costs were highest in the year after the first MS claim and then decreased...
May 18, 2018: Journal of Comparative Effectiveness Research
https://www.readbyqxmd.com/read/29775084/health-state-utilities-in-patients-with-advanced-non-small-cell-lung-cancer-in-china
#2
Yunjie Shen, Bin Wu, Xiaohui Wang, Jun Zhu
AIM: Non-small-cell lung cancer (NSCLC) is a leading global health threat that impairs patient health outcomes. Health state utilities are fundamental values in economic evaluation and significantly vary across countries. Given the scarce data on the Chinese population, the current study measured utility values in the Chinese patients with NSCLC. METHODS: This study was conducted as a cross-sectional survey of patients with advanced NSCLC at the Shanghai Chest Hospital...
May 18, 2018: Journal of Comparative Effectiveness Research
https://www.readbyqxmd.com/read/29775083/comparing-efficacy-of-enteral-nutrition-plus-ranitidine-and-enteral-nutrition-alone-as-stress-ulcer-prophylaxis
#3
Anahid Nourian, Mostafa Mohammadi, Mohammad-Taghi Beigmohammadi, Mohammad Taher, Zohreh Dadvar, Masoume Malekolkottab, Masoud Ramezani, Hossein Khalili
AIM: Adequacy of enteral nutrition (EN) alone as stress ulcer prophylaxis (SUP) is controversial. The aim of this study was to compare efficacy of EN alone and ranitidine plus EN as SUP. METHOD: Critically ill adults with indications to receive SUP were randomized to ranitidine 50 mg IV every 8 h plus EN (SUP) or EN alone (non-SUP) group for 7 days. Besides, endoscopy was performed at the time of recruitment and on day 7. RESULTS: During the study period, only one patient in each group of SUP and non-SUP experienced gastrointestinal bleeding...
May 18, 2018: Journal of Comparative Effectiveness Research
https://www.readbyqxmd.com/read/29775075/authors-lack-of-awareness-and-use-of-core-outcome-set-on-postoperative-pain-in-children-is-hindering-comparative-effectiveness-research
#4
Krste Boric, Matija Boric, Svjetlana Dosenovic, Antonia Jelicic Kadic, Marijan Batinic, Marija Cavar, Milka Jeric, Livia Puljak
AIM: To analyze awareness about and acceptability of core outcome set (COS) for pediatric pain recommended by the PedIMMPACT. METHODS: We invited authors of systematic reviews and randomized controlled trials about interventions for postoperative pain in children to participate in a survey. RESULTS: Only a third of surveyed authors of systematic reviews and randomized controlled trials about postoperative pain in children had heard about the PedIMMPACT COS for acute pediatric pain...
May 18, 2018: Journal of Comparative Effectiveness Research
https://www.readbyqxmd.com/read/29770704/estimating-efficiency-of-directive-2011-24-eu-cross-border-healthcare-in-member-states
#5
Mustapha D Ibrahim, Mevhibe B Hocaoglu, Berna Numan, Sahand Daneshvar
AIM: Directive 2011/24/EU on patients' rights in cross-border healthcare facilitates EU citizens' access to and reimbursement for healthcare provided or prescribed in a member state other than the member state of affiliation. MATERIALS & METHODS: The efficiency of cross-border healthcare policy is evaluated using data envelopment analysis of relevant items in Eurobarometer Survey on Safety and Quality of Care and Patients' Rights in the EU. RESULTS: Our study shows policy inefficiency in 52% of the 25 EU member states included in the analysis...
May 17, 2018: Journal of Comparative Effectiveness Research
https://www.readbyqxmd.com/read/29762046/effects-of-calcimimetics-on-long-term-outcomes-in-dialysis-patients-literature-review-and-bayesian-meta-analysis
#6
Greta Lozano-Ortega, Nathalie Waser, Mark E Bensink, Sarah Goring, Heather Bennett, Geoffrey A Block, Glenn M Chertow, Marie-Louise Trotman, Kerry Cooper, Adrian R Levy, Vasily Belozeroff
AIM: Randomized controlled trials (RCTs) with clinical outcomes are considered the gold standard for regulatory approval. However, by design they are only able to answer a small number of clinical questions. Other high-quality studies are required for clinical decision-making. The EVOLVE was the largest RCT, evaluating the effects of cinacalcet on clinical outcomes among adult patients receiving maintenance dialysis suffering from secondary hyperparathyroidism. While the EVOLVE trial did not reach its primary end point, imbalance in subjects' age at randomization and discontinuation rates are two of the reasons that the lack of mortality benefit is in question...
May 15, 2018: Journal of Comparative Effectiveness Research
https://www.readbyqxmd.com/read/29754518/cost-of-treating-peripheral-neuropathic-pain-with-pregabalin-or-gabapentin-at-therapeutic-doses-in-routine-practice
#7
Antoni Sicras-Mainar, Javier Rejas-Gutiérrez, Maria Perez-Paramo, Ruth Navarro-Artieda
AIM: To analyze the cost of peripheral neuropathic pain (PNP) treatment with pregabalin or gabapentin at therapeutic doses in routine clinical practice. METHODS: Analysis of a retrospective, observational study of electronic medical records of patients treated for PNP with therapeutic doses of pregabalin or gabapentin, with 2 years' follow-up, considering PNP type, comorbidities, concomitant analgesia and resource use. RESULTS: The weighted total average cost/patient was lower for pregabalin than gabapentin (€2464 [2197-2730] vs €3142 [2670-3614]; p = 0...
May 14, 2018: Journal of Comparative Effectiveness Research
https://www.readbyqxmd.com/read/29722547/adherence-and-economic-impact-of-paliperidone-palmitate-versus-oral-atypical-antipsychotics-in-a-medicare-population
#8
Kruti Joshi, Erik Muser, Yihua Xu, Phil Schwab, Manasi Datar, Brandon Suehs
AIM: To compare adherence, healthcare utilization and costs among real world, Medicare-eligible patients with schizophrenia using long-acting injectable paliperidone palmitate (PP) versus oral atypical antipsychotics. Patients & methods: Historical cohort study used Medicare Advantage claims data. Inverse probability of treatment weighting was applied to adjust for baseline differences. 12-month adherence, healthcare utilization and costs were compared. RESULTS: Patients using PP were more adherent (proportion of days covered ≥0...
May 3, 2018: Journal of Comparative Effectiveness Research
https://www.readbyqxmd.com/read/29697278/efficacy-and-metabolic-effects-of-lurasidone-versus-brexpiprazole-in-schizophrenia-a-network-meta-analysis
#9
Daisy Ng-Mak, Vanita Tongbram, Kerigo Ndirangu, Krithika Rajagopalan, Antony Loebel
AIM: To assess the relative efficacy and metabolic effects of lurasidone and brexpiprazole in the acute treatment of schizophrenia. METHODS: Five lurasidone and three brexpiprazole trials were identified. In the absence of head-to-head trials, a Bayesian network meta-analysis comparing lurasidone and brexpiprazole was performed. RESULTS: Nonstatistically significant differences in efficacy measures were observed between lurasidone and brexpiprazole...
April 26, 2018: Journal of Comparative Effectiveness Research
https://www.readbyqxmd.com/read/29694244/cost-effectiveness-of-long-acting-injectable-aripiprazole-once-monthly-400-mg-in-bipolar-i-disorder-in-the-usa
#10
Margarida Augusto, Mallik Greene, Maëlys Touya, Samantha Min Sweeney, Heidi Waters
AIM: To evaluate the cost-effectiveness of aripiprazole once-monthly 400/300 mg (AOM 400) in maintenance monotherapy treatment of bipolar I disorder (BP-I). METHODS: A de novo lifetime Markov model was developed for BP-I using available data for AOM 400 and relevant comparators. Base-case analysis considered costs and outcomes from the US payer perspective. RESULTS: The cost per quality-adjusted life year gained with AOM 400 versus comparators ranged from US$2007 versus oral asenapine to dominance (i...
April 25, 2018: Journal of Comparative Effectiveness Research
https://www.readbyqxmd.com/read/29694243/budget-impact-analysis-of-long-acting-injectable-aripiprazole-once-monthly-400-mg-in-bipolar-i-disorder-in-the-usa
#11
Margarida Augusto, Mallik Greene, Maëlys Touya, Samantha Min Sweeney, Heidi Waters
AIM: To estimate the budget impact (BI) of introducing aripiprazole once-monthly 400 mg/300 mg (AOM 400) in the maintenance monotherapy treatment of bipolar I disorder versus long-acting injectables, oral antipsychotics and best supportive care. METHODS: A BI model was developed from a US-payer perspective using treatment-related, hospitalization and adverse event management cost estimates for a hypothetical 1,000,000-member health plan over a 5-year period. RESULTS: Market share of AOM 400 was predicted to increase from 0...
April 25, 2018: Journal of Comparative Effectiveness Research
https://www.readbyqxmd.com/read/29692179/an-indirect-comparison-of-intravenous-and-subcutaneous-belimumab-efficacy-in-patients-with-sle-and-high-disease-activity
#12
Sulabha Ramachandran, Daniel Parks, Milena Kurtinecz, David A Roth, Rafael Alfonso-Cristancho
AIM: To compare the efficacy of intravenous (IV) and subcutaneous (SC) belimumab plus standard therapy in patients with active, autoantibody-positive systemic lupus erythematosus and high disease activity (HDA). PATIENTS & METHODS: An indirect treatment comparison using patient-level data of patients with HDA from three belimumab IV Phase III randomized controlled trials (BLISS-52 [BEL110751]; BLISS-76 [BEL110752]; North-East Asia Study [BEL113750]) and one belimumab SC randomized controlled trial (BLISS-SC [BEL112341])...
April 25, 2018: Journal of Comparative Effectiveness Research
https://www.readbyqxmd.com/read/29682984/clinical-and-economic-benefits-of-advanced-microplegia-delivery-system-in-cardiac-surgery-evidence-from-250-hospitals
#13
Marc W Gerdisch, Scott Robinson, Guy David, Stephanie Makepeace, Michael P Ryan, Candace Gunnarsson
AIM: Determine the impact of a second generation microplegia delivery system (MPS2) compared with traditional cardioplegia. Materials &  methods: Multivariable difference-in-differences analysis using fixed effects was performed for each outcome: adverse event (AE) composite, total visit cost, medication cost, length of stay (LOS) and  intensive care unit (ICU) days. RESULTS: A 2.25% absolute risk reduction in AE composite was found with MPS2 compared with traditional cardioplegia, which equates to relative risk reduction of 5...
April 23, 2018: Journal of Comparative Effectiveness Research
https://www.readbyqxmd.com/read/29589475/analysis-of-indirect-treatment-comparisons-in-national-health-technology-assessment-assessments-and-requirements-for-industry-submissions
#14
Ischa J Es-Skali, John Spoors
AIM: To determine the preferred methodologies of health technology assessment (HTA) agencies across Europe, Canada and Australia to ascertain acceptance of indirect treatment comparisons (ITC) as a source of comparative evidence. METHOD: A review of official submission guidelines and analysis of comments in HTA submissions that have used different ITC methodologies. CONCLUSION: ITC is generally accepted as a technique that allows demonstration of noninferiority to a comparator provided the chosen methodology and underlying assumptions are clear and justified...
March 28, 2018: Journal of Comparative Effectiveness Research
https://www.readbyqxmd.com/read/29537304/economic-and-organizational-impact-of-the-changing-hospital-funding-practices-of-erythropoiesis-stimulating-agents-on-the-management-of-care-of-dialysis-patients-in-france
#15
Carole Therasse, Isabelle Fusier, Anne-Laure Cordonnier, Florence Bérard, Olivier Parent de Curzon, François Bocquet, Pascal Paubel
AIM: Erythropoiesis-stimulating agents (ESAs) are particularly used to treat dialysis patients suffering from anemia due to renal failure. Since March 2014, ESAs have no longer been funded on top-of-diagnosis-related groups (DRGs) in French hospitals and are funded via DRGs. There are two ways to fund dialysis in French hospitals: the 'DRG for dialysis in session' and the 'off-dialysis DRG', which is not a DRG and consists in a supplement tariff specific to dialysis for patients hospitalized for another main reason than dialysis...
March 14, 2018: Journal of Comparative Effectiveness Research
https://www.readbyqxmd.com/read/29478331/transitioning-from-learning-healthcare-systems-to-learning-health-care-communities
#16
C Daniel Mullins, La'Marcus T Wingate, Hillary A Edwards, Toyin Tofade, Anthony Wutoh
The learning healthcare system (LHS) model framework has three core, foundational components. These include an infrastructure for health-related data capture, care improvement targets and a supportive policy environment. Despite progress in advancing and implementing LHS approaches, low levels of participation from patients and the public have hampered the transformational potential of the LHS model. An enhanced vision of a community-engaged LHS redesign would focus on the provision of health care from the patient and community perspective to complement the healthcare system as the entity that provides the environment for care...
February 26, 2018: Journal of Comparative Effectiveness Research
https://www.readbyqxmd.com/read/29570366/therapeutic-approach-for-patients-with-venous-thromboembolism-attended-in-emergency-departments-during-routine-clinical-practice-the-edith-study
#17
Pedro Ruiz-Artacho, Pascual Piñera, Albert Antolin, José Ramón Casal, Marta Sanchez, Coral Suero, Marta Merlo, Jorge Carriel, Mar Genis, Sonia Jimenez
AIM: To analyze treatment at discharge/follow-up of patients diagnosed with venous thromboembolism (VTE) in the emergency department (ED). MATERIALS & METHODS: Ambispective study (50 Spanish centers) of consecutive patients (October-December 2014) with VTE diagnosed in ED. RESULTS: VTE was diagnosed in 775 patients (295 pulmonary embolism [PE] without deep vein thrombosis [DVT], 389 DVT without PE and 91 PE + DVT); 95.5% received anticoagulants (90...
April 2018: Journal of Comparative Effectiveness Research
https://www.readbyqxmd.com/read/29553286/survival-comparison-of-hepatocellular-carcinoma-patients-treated-with-radioembolization-versus-nonoperative-interventional-treatment
#18
David Thayer, Christopher Noda, Resmi Charalel, Abigail Mills, Randy Chang, Yu Tao, Olaguoke Akinwande
AIM: To compare the overall survival (OS) and liver cancer-specific survival of advanced-stage hepatocellular carcinoma (HCC) patients who received transarterial radioembolization (TARE) with those who received nonoperative/interventional treatment (NOT). MATERIALS & METHODS:  A total of 12,520 HCC patients from the Surveillance, Epidemiology and End Results database were categorized by treatment with either radioembolization or NOT. Kaplan-Meier and multivariate Cox regression were conducted...
April 2018: Journal of Comparative Effectiveness Research
https://www.readbyqxmd.com/read/29542364/comparison-of-therapies-in-lumbar-degenerative-disc-disease-a-network-meta-analysis-of-randomized-controlled-trials
#19
Jack Zigler, Nicole Ferko, Chris Cameron, Leena Patel
AIM: To compare the efficacy and safety of total disc replacement, lumbar fusion, and conservative care in the treatment of single-level lumbar degenerative disc disease (DDD). MATERIALS & METHODS: A network meta-analysis was conducted to determine the relative impact of lumbar DDD therapies on Oswestry Disability Index (ODI) success, back pain score, patient satisfaction, employment status, and reoperation. Odds ratios or mean differences and 95% credible intervals were reported...
March 2018: Journal of Comparative Effectiveness Research
https://www.readbyqxmd.com/read/29537878/number-needed-to-treat-in-indirect-treatment-comparison
#20
Patricia Guyot, Wei Cheng, Gabriel Tremblay, Ronda Copher, Heather Burnett, Xuan Li, Charles Makin
AIM: For dichotomous outcomes, odds ratio (OR) is one of the usual summary measures of indirect treatment comparison. A corresponding number needed to treat (NNT) estimate may facilitate understanding of the treatment effect. METHODS: We show how to estimate NNT based on OR results of a matching adjusted indirect comparison. We also have derived the explicit formula of its 95% CIs by applying the delta method, and as an alternative, a simulation-based method. RESULTS: The method was applied in a case study example in radioiodine-refractory differentiated thyroid cancer (RR-DTC) patients, comparing lenvatinib to sorafenib...
March 2018: Journal of Comparative Effectiveness Research
journal
journal
43925
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"