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Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology

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https://www.readbyqxmd.com/read/28918854/erratum-to-extramammary-paget-s-disease-of-the-oral-mucosa-and-perioral-skin-oral-surg-oral-med-oral-pathol-oral-radiol-2017-124-2-e157-e163
#1
Xiangjian Wang, Lanyan Wu, Xueke Shi, Xin He, Wei Li, Hongmei Zhou
No abstract text is available yet for this article.
September 11, 2017: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
https://www.readbyqxmd.com/read/28941993/dna-methylation-polymerase-chain-reaction-pcr-array-of-apoptosis-related-genes-in-pleomorphic-adenomas-of-the-salivary-glands
#2
Núbia Braga Pereira, Ana Carolina de Melo do Carmo, Kelma Campos, Sara Ferreira Dos Santos Costa, Marina Gonçalves Diniz, Ricardo Santiago Gomez, Carolina Cavalieri Gomes
OBJECTIVE: The aim of this study was to evaluate the DNA methylation profile in 22 apoptosis-related genes in pleomorphic adenomas (PAs) of the salivary glands, in comparison with normal salivary glands (NSGs), and to address the differences in methylation patterns between smaller and larger tumors. Additionally, we investigated if the hypermethylation of differentially methylated genes between NSGs and PAs impacted the messenger RNA (mRNA) transcription. DESIGN: Twenty-three fresh PA samples and 12 NSG samples were included...
August 31, 2017: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
https://www.readbyqxmd.com/read/28939244/clinicopathologic-significance-of-in-vivo-antinuclear-autoantibodies-in-oral-mucosal-biopsies
#3
Rana Alshagroud, Mirdza Neiders, Jill M Kramer, Lakshmanan Suresh
OBJECTIVE: Although antinuclear autoantibody (ANA) staining of oral biopsy specimens is indicative of chronic ulcerative stomatitis, it is not known whether this staining is characteristic of other autoimmune diseases. Our study was undertaken to characterize the various in vivo ANA patterns detected in the oral mucosa by direct immunofluorescence to describe the associated hematoxylin and eosin findings, and determine whether patients with these findings had a coexisting systemic connective tissue disease...
August 24, 2017: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
https://www.readbyqxmd.com/read/28927729/contrast-enhanced-ultrasound-for-diagnosis-of-an-enlarged-cervical-lymph-node-in-a-patient-with-oropharyngeal-cancer-a-case-report
#4
Shalva R Gvetadze, Ping Xiong, Jiang Li, Mingming Lv, Jun Li, Xin Yang, Konstantin D Ilkaev, Jian Sun
In oral and oropharyngeal cancer, the presence of regional neck metastasis strongly influences treatment planning and survival prognosis. A number of imaging techniques can be utilized in the clinic for diagnosis and staging. A patient with oropharyngeal cancer was staged T2 cN1 after clinical examination, computed tomography, and (18)F-fluorodeoxyglucose positron emission tomography with computed tomography. Contrast-enhanced microbubble imaging was applied for diagnosis of a lymph node suspected of harboring a metastasis...
August 24, 2017: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
https://www.readbyqxmd.com/read/28918879/axitinib-related-osteonecrosis-of-the-jaw
#5
Vinod Patel, Chris Sproat, Jerry Kwok, Nikki Tanna
Tyrosine kinase inhibitors (TKIs) are oral chemotherapy drugs used primarily to treat leukemias, renal cell carcinomas, gastrointestinal stromal tumors, and neuroendocrine tumors. Within this group, a number of drugs have already been implicated in jaw necrosis. Axitinib (Inlyta) is a novel TKI currently licensed for the treatment of renal cell carcinoma. We report the first case, to our knowledge, of jaw necrosis solely related to this medication and review the literature surrounding TKIs and their implication in osteonecrosis of the jaw...
August 18, 2017: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
https://www.readbyqxmd.com/read/28923296/malignant-transformation-of-oral-leukoplakia-in-a-patient-with-dyskeratosis-congenita
#6
Michelle Bongiorno, Shayna Rivard, Daniel Hammer, Joshua Kentosh
Dyskeratosis congenita (DC) is a rare, inherited, bone marrow failure syndrome caused by premature telomere shortening. The classic mucocutaneous triad of clinical features comprises reticulated skin pigmentation, nail dysplasia, and oral leukoplakia. Multiple somatic features, including bone marrow failure, pulmonary fibrosis, and liver disease, are also common. DC significantly increases the risk for malignant transformation, including myelodysplastic syndrome, acute myeloid leukemia, head and neck squamous cell carcinoma, and anogenital cancer...
August 12, 2017: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
https://www.readbyqxmd.com/read/28870703/a-novel-mutation-at-antxr1-in-an-indian-patient-with-growth-retardation-alopecia-pseudoanodontia-optic-atrophy-syndrome
#7
Esita Chattopadhyay, Sandip Ghose, Anindita Ray, Nishat Anjum, Anjana Mazumdar, Bidyut Roy
OBJECTIVE: Growth retardation-alopecia-pseudoanodontia-optic atrophy (GAPO) syndrome (Online Mendelian Inheritance in Man [OMIM] ID 230740) is one of the rarest autosomal recessive syndromes. It is characterized by many phenotypes, including wide anterior fontanel, frontal bossing of the face, depressed nasal bridge, along with the 4 classic phenotypes contained in the name of the syndrome. Recent reports identified nonsense, missense, and splicing mutations at different exons of ANTXR1 responsible for GAPO syndrome in patients from different ethnic populations...
August 4, 2017: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
https://www.readbyqxmd.com/read/28867464/is-cone-beam-computed-tomography-accurate-for-postoperative-evaluation-of-implants-an-in-vitro-study
#8
Michele Machado Vidor, Gabriela Salatino Liedke, Mathias Pante Fontana, Heraldo Luis Dias da Silveira, Nadia Assein Arus, André Lemos, Mariana Boessio Vizzotto
OBJECTIVE: The aim of this study was to evaluate the accuracy of cone beam computed tomography (CBCT) for evaluation of the bone-implant interface in comparison with periapical radiography. STUDY DESIGN: Titanium implants were inserted in 74 bovine rib blocks in intimate contact with bone walls and with a gap of 0.125 mm (simulating failure in the osseointegration process). Periapical radiographs were taken with conventional film, and CBCT scans were acquired with i-CAT (0...
August 3, 2017: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
https://www.readbyqxmd.com/read/28867463/oral-lichen-sclerosus-a-review-of-clinical-presentation-treatment-and-clinical-outcomes
#9
REVIEW
Stephanie L Bevans, Jordan M Keeley, Naveed Sami
OBJECTIVE: The aim of this study was to evaluate the disease involvement, treatment and response, and malignant potential of oral lichen sclerosus (LS). STUDY DESIGN: We conducted a review of the literature of 37 cases of oral LS. We looked specifically for the following data: patient demographic characteristics, disease involvement, treatment, response to treatment, duration of follow-up, symptoms, risk factors for oral malignancy, and malignant transformation...
August 3, 2017: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
https://www.readbyqxmd.com/read/28864293/dna-methylation-profiles-of-22-apoptosis-related-genes-in-odontogenic-keratocysts-before-and-after-marsupialization
#10
Karuza Maria Alves Pereira, Sara Ferreira Dos Santos Costa, Núbia Braga Pereira, Marina Gonçalves Diniz, Wagner Henriques Castro, Carolina Cavaliéri Gomes, Ricardo Santiago Gomez
OBJECTIVE: Odontogenic keratocysts (OKCs) are cystic lesions of the jaw and tend to recur after treatment. Marsupialization is an effective preliminary treatment for large OKCs. This procedure induces epithelial lining changes in association with reduction of Bcl-2 protein expression, but the underlying mechanisms remain unknown. The purpose of our study was to compare the methylation profile of the apoptosis-related genes of OKCs before and after marsupialization. STUDY DESIGN: We assessed the methylation percentages of the promoter region of 22 apoptosis-related genes in 13 OKCs, both marsupialized and nonmarsupialized lesions, by using methylation quantitative polymerase chain reaction array...
August 3, 2017: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
https://www.readbyqxmd.com/read/28867462/use-of-cone-beam-computed-tomography-to-assess-significant-imaging-findings-related-to-mandibular-third-molar-impaction
#11
Louise Hauge Matzen, Lars Schropp, Rubens Spin-Neto, Ann Wenzel
OBJECTIVE: The aim of the study was to identify risk factors for pathoses related to mandibular third molars observed in cone beam computed tomography. STUDY DESIGN: Cone beam computed tomography volumes of 410 mandibular third molars were assessed by 3 observers, according to the angulation and position of the third molar in relation to the second molar. In addition, pathoses (marginal bone loss, resorption of the second molar, increased follicular space and lingual bone perforation) were assessed...
August 2, 2017: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
https://www.readbyqxmd.com/read/28866360/quantitative-assessment-of-mandibular-canal-compression-assessed-by-cone-beam-computed-tomography
#12
Fatima M Jadu, Daniah Alhazmi, Fatma F Badr, Ahmed M Jan
OBJECTIVE: The aim of this study was to objectively quantify the topographic relation of the mandibular canals, impacted third molars, and cortical plates using cone beam computed tomography (CBCT). STUDY DESIGN: A retrospective chart review was conducted using the database of a university-based imaging service. Two calibrated reviewers examined the CBCT images of 100 cases scheduled for mandibular third molar removal. They characterized the position and condition of the mandibular canal and measured its dimensions at 3 different points relative to the third molars...
August 2, 2017: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
https://www.readbyqxmd.com/read/28866361/targeted-next-generation-sequencing-of-glandular-odontogenic-cyst-a-preliminary-study
#13
Elisa Carvalho de Siqueira, Silvia Ferreira de Sousa, Josiane Alves França, Marina Gonçalves Diniz, Thaís Dos Santos Fontes Pereira, Rennan Garcias Moreira, Pablo Agustin Vargas, Ricardo Santiago Gomez, Carolina Cavalieri Gomes
OBJECTIVE: Glandular odontogenic cyst (GOC) is an uncommon developmental cyst. Its molecular pathogenesis is unclear, and deep sequencing may help identify causative low-frequency variants in tumors. We investigated in GOC mutations in 50 genes commonly altered in human cancers. STUDY DESIGN: Targeted next-generation sequencing was used to interrogate a panel of approximately 2800 mutations in GOC. RESULTS: Six missense single nucleotide variations (SNVs) were reported...
July 26, 2017: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
https://www.readbyqxmd.com/read/28847629/analysis-of-the-correlation-between-dental-arch-and-articular-eminence-morphology-a-cone-beam-computed-tomography-study
#14
Francielle Silvestre Verner, Gina Delia Roque-Torres, Laura Ricardina Ramírez-Sotello, Karina Lopes Devito, Solange Maria Almeida
OBJECTIVE: The aim of the study was to assess the correlation between the morphology of the dental arches (DAs) of patients with normal occlusion and of the articular eminence (AE) by using cone beam computed tomography (CBCT). STUDY DESIGN: CBCT scans of 60 patients were evaluated in terms of height and inclinations (angles α, β, and δ) of the AE. DAs were classified according to their shapes (tapered, square, ovoid), and their perimeters, widths, and depths were measured...
July 26, 2017: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
https://www.readbyqxmd.com/read/28743665/the-american-academy-of-oral-medicine-clinical-practice-statement-medication-induced-oral-reactions
#15
EDITORIAL
Eric T Stoopler
No abstract text is available yet for this article.
July 22, 2017: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
https://www.readbyqxmd.com/read/28732697/cytological-study-of-dna-content-and-nuclear-morphometric-analysis-for-aid-in-the-diagnosis-of-high-grade-dysplasia-within-oral-leukoplakia
#16
Xi Yang, Xuan Xiao, Wenyan Wu, Xuemin Shen, Zengtong Zhou, Wei Liu, Linjun Shi
OBJECTIVE: To quantitatively examine the DNA content and nuclear morphometric status of oral leukoplakia (OL) and investigate its association with the degree of dysplasia in a cytologic study. STUDY DESIGN: Oral cytobrush biopsy was carried out to obtain exfoliative epithelial cells from lesions before scalpel biopsy at the same location in a blinded series of 70 patients with OL. Analysis of nuclear morphometry and DNA content status using image cytometry was performed with oral smears stained with the Feulgen-thionin method...
July 18, 2017: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
https://www.readbyqxmd.com/read/28843477/unusual-osteolytic-lesion-of-the-jaw
#17
Karine Duarte da Silva, Isadora Luana Flores, Adriana Etges, Ana Carolina Uchoa Vasconcelos, Ricardo Alves Mesquita, Ana Paula Neutzling Gomes, Sandra Beatriz Chaves Tarquinio
No abstract text is available yet for this article.
July 10, 2017: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
https://www.readbyqxmd.com/read/28822697/head-and-neck-myiasis-a-case-series-and-review-of-the-literature
#18
José Alcides Almeida de Arruda, Leni Verônica de Oliveira Silva, Pedro Urquiza Jayme Silva, Eugênia Leal de Figueiredo, Gerhilde Callou, Ricardo Alves Mesquita, Belmiro Cavalcanti do Egito Vasconcelos
OBJECTIVE: This study describes 9 cases of myiasis affecting the head and neck region and discusses the demographic distribution, treatment, clinical characteristics, and sequelae of the disease in light of the literature. STUDY DESIGN: The study was performed in 2 steps. In the first part, 9 cases seen over a period of 10 years at the Emergency Department of Hospital da Restauração in Brazil were studied. In the second part, a literature search was performed in PubMed for articles on head and neck myiasis published from 1975 to March 2017...
July 5, 2017: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
https://www.readbyqxmd.com/read/28822696/influence-of-surgical-decompression-on-the-expression-of-inflammatory-and-tissue-repair-biomarkers-in-periapical-cysts
#19
Janderson Teixeira Rodrigues, Henrique Dos Santos Antunes, Luciana Armada, Fábio Ramôa Pires
OBJECTIVE: The biologic effects of surgical decompression on the epithelium and connective tissues of periapical cysts are not fully understood. The aim of this study was to evaluate the expression of tissue repair and inflammatory biomarkers in periapical cysts before and after surgical decompression. STUDY DESIGN: Nine specimens of periapical cysts treated with decompression before undergoing complete enucleation were immunohistochemically analyzed to investigate the expression of interleukin-1β, tumor necrosis factor-α, transforming growth factor-β1, matrix metalloproteinase-9, Ki-67, and epidermal growth factor receptor...
July 5, 2017: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
https://www.readbyqxmd.com/read/28822695/large-bulging-mass-of-the-posterior-mandible-in-a-child
#20
Eunae Sandra Cho, Hyun Sil Kim, Jae-Young Kim
No abstract text is available yet for this article.
July 5, 2017: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
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