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Danish Medical Journal

Nina Ank, Mona Kjærsgaard, Rita Andersen Leth
INTRODUCTION: Our objective was to investigate the know-ledge of "Guidelines on prescribing antibiotics for physicians and others in Denmark" published by the Danish Health Au-thority in 2012, and the usefulness of these guidelines for Danish hospital doctors. METHODS: We collected information on the perceived aware-ness and usefulness of the guidelines using a ques-tionnaire distributed at two regional hospitals. Furthermore, to evaluate the use of the guidelines, we collected data about 310 patients treated with antimicrobials at the two hospitals...
July 2018: Danish Medical Journal
Kirsten Hansen, Ole Kristensen, Hans Søgaard, Kaj Christensen
INTRODUCTION: Offspring of parents with depression has an increased risk of experiencing somatic and psychiatric diseases. Early child support can reduce this risk. This study aimed to describe general practitioners' (GPs) professional attention to children of depressed patients. METHODS: This was a survey study. We mailed ques-tion-naires to randomly selected Danish GPs. RESULTS: Among the 1,760 GPs invited, 890 (51%) partici-pated. Female GPs accounted for 45% of the respondents and 41% of the total GP population (p = 0...
July 2018: Danish Medical Journal
Lotte Linnemann Rønfeldt, Dorthe Hjort Jakobsen, Henrik Kehlet, Henriette Lipczak, Kasper Wennerwaldt
INTRODUCTION: Clinical practice guidelines (CPGs) support enhanced post-operative recovery and decrease morbidity. In addition, patient information leaflets (PILs) are associated with enhanced overall outcomes and improved patient satisfaction. The aim of this study was to provide an overview of the quality of CPGs and PILs in cancer surgery departments undertaking pulmonary lobectomy, nephrectomy, cystectomy, whipples, colorectal and ovarian surgery. METHODS: We conducted a cross-sectional descriptive study within 44 surgical departments in six cancer subspecialties: lung (n = 4), kidney (n = 9), bladder (n = 5), pancreas (n = 4), colorectal (n = 18) and ovarian (n = 4)...
June 2018: Danish Medical Journal
Bashir Fouad Khazen, Alaa El-Hussuna
INTRODUCTION: A supra-physiological dose of glucocorticoid (SDS) is administered routinely in the perioperative management of patients on long-term regular glucocorticoid therapy. The dose of glucocorticoid used in these regimens varies. The current treatment is based on two 60-year-old case reports. No data exist to document the required dose of glucocorticoid to prevent perioperative hypotension or the category of patients needing this dose. Having in mind that high doses of glucocorticoids have several potential side effects, this practice ought to be re-evaluated in the light of available evidence...
June 2018: Danish Medical Journal
Sofie Ryaa, Lina H Ingelsrud, Søren T Skou, Ewa M Roos, Anders Troelsen
INTRODUCTION: The Good Life with osteoArthritis in Denmark (GLA:D) programme consists of patient education and supervised exercise therapy and adheres to clinical guidelines for knee osteoarthritis (OA). The purpose of this study was to present the treatment choice and clinical results of patients who were advised to participate in GLA:D before deciding on undergoing knee replacement. METHODS: Patient records from all patients with knee OA consulting one orthopaedic surgeon in 2015 were reviewed to identify those who were advised to seek GLA:D...
June 2018: Danish Medical Journal
Mathilde Glud Christensen, Katrine Storm Piper, Rasmus Dreier, Charlotte Suetta, Hanne Elkjær Andersen
INTRODUCTION: The prevalence of sarcopenia varies extensively depending on the definitions and studied populations. The aim of this study was to assess the prevalence of sarcopenia in a Danish geriatric out-patient population using criteria from the European Working Group on Sarcopenia (EWGSOP). METHODS: Patients referred to a geriatric out-patientclinic were included. Using the EWGSOP´s recommendations, appendicular skeletal muscle mass (ASM), hand-grip strength (HGS) and gait speed (ten-meter walk (GS)) were assessed...
June 2018: Danish Medical Journal
Camilla Buch Kjølbye, Thomas Bo Drivsholm, Ruth Kirk Ertmann, Kirsten Lykke, Rasmus Køster Rasmussen
INTRODUCTION: There is no evidence on how motor function is best evaluated in children in a low-risk setting. The method used in the Danish Preventive Child Health Examination Programme (DPCHEP) in general practise has not been validated. The objective of this review was to identify existing motor function tests for 0-2-year-old children that were validated for use in the background population and which are suitable for use in the DPCHEP. METHODS: This systematic review was conducted in accordance with the PRISMA guidelines...
June 2018: Danish Medical Journal
Niels Christian Kaldau, Stig Brorson, Per Hölmich, Bent Lund
INTRODUCTION: Short-term outcome after hip arthroscopy for femoroacetabular impingement (FAI) has been reported to improve hip function and decrease pain. Only few midterm and long-term studies have been published. The objective of this study was to report midterm results in a consecutive cohort and to study the relation between cartilage lesions and the conversion rate to total hip arthroplasty (THA). METHODS: Eighty-four FAI patients were followed retrospectively for 6-8 years...
June 2018: Danish Medical Journal
Sabrina Jensen, Lotte B Colmorn, Anne-Mette Schroll, Lone Krebs
Correction per 30 April 2018. In a letter from Ole Olsen et al [1] it was disclosed, that there were mathematical errors in the incidences of complications among nulliparous women with hospital births presented in Table 2. Incidences and p-values have been recalculated, and the errors in Table 2 have been corrected. We apologise for this. The corrections did not lead to any other changes in the manuscript [1].
May 2018: Danish Medical Journal
Ida Charlotte Bay Lund, Naja Becher, Olav Bjørn Petersen, Melissa Hill, Lyn Chitty, Ida Vogel
INTRODUCTION: Cell-free DNA testing (cfDNA testing) in maternal plasma has recently been implemented in Danish healthcare. Prior to that we wanted to evaluate the preferences among pregnant women, partners and health professionals regarding cfDNA testing compared with invasive prenatal diagnostics. METHODS: Responders were recruited at public hospitals in the Central and North Denmark Regions. Stated preferences for prenatal testing were obtained through an online questionnaire incorporating a discrete choice experiment...
May 2018: Danish Medical Journal
Finn Ole Larsen, Anne Birgitte Christiansen, Anette Rishøj, Knud Mejer Nelausen, Dorte L Nielsen
INTRODUCTION: The purpose of this study was to evaluate the safety and feasibility of home-based chemotherapy and to compare chemotherapy given at home with chemotherapy given as an outpatient treatment in relation to toxicity, quality of life and patient's preference. METHODS: Patients who had undergone radical surgery for colon cancer and who were eligible to receive adjuvant treatment with capecitabine and oxaliplatin could be included. To ensure patient safety, the first infusion was given at an outpatient clinic...
May 2018: Danish Medical Journal
Tine Nielsen, Martin Bang Jensen, Egon Stenager, Andreas Dammann Andersen
INTRODUCTION: The diagnosis of Parkinson's disease (PD) is typically based on the presence of motor symptoms, but in the early phase of the disease, the diagnostic process can be challenging. Examination of non-motor symptoms in patients suspected of PD has gained growing attention. Olfactory tests have shown promising results as ancillary diagnostic tests. The aim of this study was to investigate how olfactory tests may be used clinically in diagnostic process in PD. METHODS: A systematic search was conducted in PubMed for relevant literature on 8 March 2017...
May 2018: Danish Medical Journal
Christine P Holler, Nicolai Lohse, Nicolai B Foss
INTRODUCTION: The prevalence of hip dislocations after total hip arthroplasty (THA) is 2-4% in Denmark. Patients with a dislocated THA are often elderly citizens with comorbidities and severe pain in the pre-reposition phase. Evidence as to which method of anaesthesia and airway management is best for hip relocation is lacking. The aim of this study was to determine how anaesthesiologists in Denmark provide anaesthesia for relocation of THAs, and if a local guideline is available. METHODS: A questionnaire was distributed by e-mail to all members of the Danish Association of Anaesthesiology and Intensive Care and the Danish Society of Young Anaesthesiologists...
May 2018: Danish Medical Journal
Nina Hardgrib, Martin Gottliebsen, Ole Rahbek, Michel Bach Hellfritzsch, Bjarne Møller-Madsen
INTRODUCTION: Genu valgus is a condition characterised by a lateral shift of the knee's mechanical axis. The deformity can be characterised using clinical examinations and long hip-knee-ankle (HKA) angles, but it is unclear how these investigations correlate with each other. Our aim was to examine the correlation between clinical and radiographic measurements of the lower extremities in children. METHODS: A total of 49 children between 5.9 and 16.7 years of age who had been referred with genu valgum deformity were included...
May 2018: Danish Medical Journal
Christian Fagernæs, Susanne Mallet
INTRODUCTION: The purpose of this study was to explore if there was a correlation between joint level and degree of contracture on the one hand and the risk of skin tear in Dupuytren's disease (DD) on the other, when treated with collagenase from Clostridium histolyticum. No trial or study has explored the risk of skin tear as primary outcome in a population that has not been treated for DD before. METHODS: A retrospective study of prospectively collected data was performed on patients with DD treated with collagenase from 1 August 2012 to 1 April 2014...
May 2018: Danish Medical Journal
Ida M Heerfordt
Exposure to ultraviolet radiation (UVR) from the sun is the main risk factor for development of skin cancer. The incidence of skin cancer in Denmark and worldwide is high and increasing. The overall aim was to achieve basic knowledge about sun protection with sunscreen among beachgoers in Denmark. Other aims were to establish a method to investigate sunscreen distribution on the body and to test two approaches to optimize the used amount and body distribution of sunscreen. Furthermore, time and duration of a beach visit and use of protective clothes among beachgoers were determined to investigate the risk the beachgoers expose themselves to...
April 2018: Danish Medical Journal
Jesper Roed Sorensen
Surgery - is it any good for goiter? In patients with goiter the benefits of thyroid surgery have previously rarely been investigated, as only few alternatives existed. However, the increasing evidence of the advantages with non-surgical substitutes with lower costs and preferable risk profiles prompted us to investi-gate the evidence base for thyroid surgery thoroughly. This thesis consists of three published studies investigating the impact of thyroidectomy on: 1) changes in disease-specific quality of life, 2) swallowing symptoms and esophageal motility, and 3) tracheal anatomy and airflow, in a cohort of patients with benign nodular goiter...
April 2018: Danish Medical Journal
Charlotte Holm
Iron deficiency and anaemia in the puerperium are associated with several important clinical consequences, most prominently physical fatigue. Current treatment practice with oral iron supplementation is associated with gastrointestinal side-effects and subsequent poor compliance. Red blood cell transfusion is also widely used to treat severe postpartum anaemia, though accumulating evidence questions its risk-benefit ratio. Intravenous iron has in previous studies been associated with fast improvement of haemoglobin and iron biochemical markers in the treatment of postpartum anaemia, but there is a lack of studies on patient reported outcomes...
April 2018: Danish Medical Journal
Camilla Groth
Tourette syndrome (TS) is a childhood onset neurodevelopmental disorder characterised by motor and vocal tics and frequent associated comorbidities. The developmental trajectory of tic shows tic-onset in the age of 4-6, peak in the age of 10-12 and decline during adolescence, although only few and small longitudinal studies form the basis of this evidence. Recent studies suggest that comorbid obsessive-compulsive disorder (OCD), attention deficit-hyperactivity disorder (ADHD) and coexisting psychopathologies tend to persist and become more dominant in adolescence...
April 2018: Danish Medical Journal
Robert Gc Riis
Knee osteoarthritis (KOA) is one of the most common causes of physical disability in the elderly population. With an increasing ageing and obese population, the prevalence of KOA is expected to rise substantially. The needs for a better understanding of the disease and tools that can predict the course of the disease, for example following treatment, are therefore imperative. 

Inflammation has over the last years been recognised as an important factor for both the symptomatology and disease course in KOA...
April 2018: Danish Medical Journal
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