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Danish Medical Journal

Freja Cecilie Barrett Mørk, Christina Gade, Marianne Thielsen, Marianne Sjølin Frederiksen, Magnus Arpi, Jesper Johannesen, Espen Jimenez-Solem, Helle Holst
INTRODUCTION: Antimicrobial stewardship programmes recommend use of narrow-spectrum antibiotics as first-line treatment of childhood pneumonia in secondary care. The primary aim of the present study was to assess whether current guidelines are followed. A secondary aim was to assess if tracheal aspiration is a useful tool in the diagnostic process of suspected childhood pneumonia. METHODS: This was a retrospective descriptive single-centre cohort study. Children between three months and 17 years with a pneumonia diagnosis were included...
November 2018: Danish Medical Journal
Ole D Wolthers
INTRODUCTION: Non-attendance in outpatient clinics may be associated with risks to patients' health, disturb the management of clinics and cause a waste of healthcare resources. The aim of the present study was to measure the non-attendance rate in a secondary paediatric outpatient centre and to assess reasons for non-attendance. METHODS: Non-attendance in children and adolescents aged 0-19 years were recorded prospectively during a year. In a telephone interview, the families of non-attending patients were asked about their reasons for non-attending...
November 2018: Danish Medical Journal
Ulla Bach Laursen, Lone Bjerregaard Rosenkilde, Anne-Mette Haugaard, Tina Obel, Ulla Toft, Mogens Lytken Larsen, Erik Berg Schmidt
INTRODUCTION: Reliable dietary information is crucial for measuring the habitual diet of healthy participants and patients with dyslipidaemia and/or coronary heart disease (CHD). Even so, methods are often complicated and time-consuming for everyone involved. We aimed to validate the new food frequency questionnaire (FFQ) named HeartDiet by comparing it to a validated 198-item FFQ and biomarkers. METHODS: Healthy local participants (n = 100) and participants with CHD from Aalborg University Hospital (n = 100) randomly completed HeartDiet and the 198-item FFQ...
November 2018: Danish Medical Journal
Eva Wiberg Torstensen, Louise Schouborg Brinth, Jesper Mehlsen, Birgitte Rahbek Kornum, Poul Jørgensen Jennum
INTRODUCTION: Human papilloma virus (HPV) vaccine uptake in girls and women is dropping markedly in some countries. Concern about the presumed side effects is the commonest reason why. Reports about side effects include specific sleep complaints such as excessive daytime sleepiness, altered dream activity and periods of muscle weakness. These symptoms are commonly seen in individuals with narcolepsy type 1. We aimed to evaluate whether HPV vaccination was associated with the development of hypocretin-deficient narcolepsy...
November 2018: Danish Medical Journal
Anh Nhi Thi Huynh, Malene Moeller Andersen, Poul Petersen, Torben Baek Hansen, Hans Kirkegaard, Jesper Bo Weile
INTRODUCTION: With the increasing use of recreational trampolines, more injuries are seen in emergency depart-ments (ED). Little is known about the relationship between adherence to safety precautions and injuries. This retro-spective study aims to describe the types of injuries and the precautions taken when using trampolines, and to investigate the relationship between injuries and safety precautions. METHODS: We reviewed patient lists and the medical records of children younger than 18 years who were treated between 1 April and 30 September 2014 at the ED of Hospital Unit West, Denmark...
November 2018: Danish Medical Journal
Saga Steinmann Madsen, Albert Gjedde, Lars Brandt, Jesper Pihl-Thingvad, Poul Videbech, Oke Gerke, Poul Flemming Højlund-Carlsen
INTRODUCTION: Stress is one of the greatest burdens of our society and often implies impairments in cognitive and emotional functions. Here, we hypothesise that changes in the brain's dopamine (DA)-based mesocorticolimbic projec-tions in patients with work-related stress (adjustment disorder) will manifest themselves as altered glucose metabolism in relation to neural activity, and as altered DA radiotracer binding potentials at the relevant receptors. METHODS: Subjects and healthy controls undergo neuropsychiatric tests and PET/MRI with three tracers: 18F-fluorodeoxyglucose to measure glucose metabolism as a marker of neural activity, 11C-raclopride to explore binding potentials in the striatum, and 11C-FLB 457 to study possibly impaired mesocortical dopaminergic transmission in the cortex...
November 2018: Danish Medical Journal
Andreas Ole Kirkegaard, Simon Thorbjørn Sørensen, Dorthe Schøler Ziegler, Leah Carreon, Mikkel Østerheden Andersen, Rikke Rousing
INTRODUCTION: In cancer patients with painful vertebral fractures due to spinal metastasis, traditional pain-relieving therapies include analgesics, bed rest, steroids, radio-ther-apy, etc. These treatment modalities are often ineffective. Traditional spinal surgery in general anaesthesia is usually not an option in patients with advanced cancer and in a poor general condition. Percutaneous vertebroplasty (PVP) has been reported as a minimally invasive treatment option with apparent rapid pain relief compared with other conventional treatment options...
October 2018: Danish Medical Journal
Raja Majid Afzal, Allan Meldgaard Lund, Flemming Skovby
INTRODUCTION: We investigated the frequency of con-sanguinity among the parents to newborns with inborn errors of metabolism (IEM) diagnosed by neonatal screening. METHODS: Data were obtained from 15 years of national newborn screening for selected IEM with autosomal recessive mode of inheritance. Among the 838,675 newborns from Denmark, The Faroe Islands and Greenland, a total of 196 newborns had an IEM of whom 155 from Denmark were included in this study. These results were crosschecked against medical records...
October 2018: Danish Medical Journal
Emilie Palmgren Colov, Tina Fransgaard, Mads Klein, Ismail Gögenur
INTRODUCTION: Colorectal cancer is the third most common type of cancer worldwide. Recurrence is an important end-point in colorectal cancer research. This study aimed to validate a previously developed algorithm to determine recurrence after surgery for rectal cancer. METHODS: Information about a cohort of 500 patients with rectal cancer was retrieved from the Danish Civil Registration System, the Danish National Patient Register and the Danish National Pathology Register...
October 2018: Danish Medical Journal
Maria Kolind Brask-Thomsen, Bodil Abild Jespersen, Mogens Grønvold, Per Sjøgren, Mette Asbjoern Neergaard
INTRODUCTION: Denmark has been ranked low regarding the extent of teaching in palliative care (PC) at medical schools although the Danish Health Authority recommends that all doctors have basic knowledge of PC. The aim of this study was to investigate the contents of and time spent on teaching in PC at the four Danish medical schools and to compare results with recommendations from the European Association of Palliative Care (EAPC). METHODS: Data were collected by examining university curricula, course catalogues, etc...
October 2018: Danish Medical Journal
Jacob Antonsen, Nina Bundgaard, Lene Holmvang, Thomas Engstrøm, Kasper Iversen
INTRODUCTION: Several studies have suggested that supine posture during pill ingestion prolongs oesophageal transit time. Whether ingesting prasugrel in an upright position leads to reduced platelet reactivity during percutaneous coronary intervention remains unclear. METHODS: A total of 20 people were randomly assigned to ingest 60 mg of prasugrel in either the supine or upright position. Platelet reactivity was analysed using the point-of-care assay VerifyNow...
October 2018: Danish Medical Journal
Thomas Maribo, Jørgen Feldbæk Nielsen, Claus Vinther Nielsen
INTRODUCTION: The aim of this study was to examine the use of standardised instruments to describe functioning in stroke patients in the transition from hospital to home-based rehabilitation. METHODS: Questionnaires were sent to 26 hospitals discharging patients with stroke and 52 primary care health services treating stroke patients at home, within an area with a population of three million. Questionnaires were targeted at healthcare professionals who typically take part in home-based stroke rehabilitation asking: "Which instruments, outcome measures or tests are commonly used to describe functioning in persons with stroke?" Instruments routinely used to assess functioning were reported...
October 2018: Danish Medical Journal
Kasper Wennervaldt, Anne Mette Kejs, Henriette Lipczak, Paul Bartels, Michael Borre, Claus Wilki Fristrup, Henrik Kehlet
INTRODUCTION: Surgical treatment for pancreatic cancer carries a high risk of both morbidity and mortality. Even so, it remains the best curative treatment option. In Denmark, pancreatic surgery has been extensively centralised since the millennium, but the effect of this centralisation on patient outcome has not been evaluated. This study describes regional variation within pancreatic surgery on a malignant indication, focusing on production volume, length of stay, readmission rates and mortality...
September 2018: Danish Medical Journal
Elisabeth Lauritzen, Asbjørn Kørvel-Hanquist, Preben Homøe
INTRODUCTION: Obstructive sleep apnoea (OSA) is an increasing health problem related to cardiovascular disease, poor quality of life, daytime sleepiness and un-restorative sleep with an estimated prevalence up to 20% in the adult population. Approximately 82% of men and 93% of women with moderate to severe OSA remain undiagnosed. Relevant, fast, accurate and cost-effective screening methods are essential. The aim of this study was to translate and validate the Danish version of the Berlin Questionnaire (BQ), and to investigate if the questionnaire can be used for screening of OSA in a Danish population...
September 2018: Danish Medical Journal
Michael Moesmann Madsen, Lone Kærsvang, Anders Würgler Hansen, Morten Flink, Henning K Nielsen, Klavs Würgler Hansen
INTRODUCTION: The Danish Adult Diabetes Database (DADD) annually reports a quality indicator for lipid-lowering treatment of type 2 diabetes mellitus (T2DM) patients. This retrospective cohort study aims to A) investigate the reasons for inadequate or lacking lipid-lowering treatment and to B) assess the validity of the DADD indicator as a measure of quality of care. METHODS: A) A pop-up questionnaire enquiring about reasons for lack of treatment was added to the clinicians' data entry tool in the Central Denmark Region...
September 2018: Danish Medical Journal
Anita Sørensen, Marianne Kleis Møller, Pernille Andreassen, Bente Malling
INTRODUCTION: A national formal advisory programme (NFAP) was introduced in Denmark in 1998. This study investigates the implementation of the NFAP and identifies areas to improve. METHODS: In March 2017, a survey was conducted among all 129 doctors employed in the first rotation of postgraduate medical education in the Central Denmark Region. A priority chart was created to appoint strengths, weaknesses, op-portunities and threats (SWOT). RESULTS: The response rate was 67%...
September 2018: Danish Medical Journal
Sumit Sen, Tove Nielsen, Erik Nielsen, Ole Pryds, Dina Cortes
INTRODUCTION: Due to the design of Hvidovre Hospital, the outpatient clinic of the Department of Paediatrics has windowless consultation rooms. Work environment surveys revealed that nurses and doctors working in these windowless rooms considered the lack of natural light a considerable health problem. This study evaluated the effects of installing light-emitting diode (LED) virtual windows in these rooms. METHODS: Four similar windowless consultations rooms located next to each other were used in the study...
September 2018: Danish Medical Journal
Kristian Kiim Jensen, Ismail Gögenur
INTRODUCTION: The extent of professional social media (SM) engagement by Danish surgeons remains unknown. It may be important for Danish surgeons to engage in SM, not only to establish and maintain an international network, but also to stay up to date on new developments in the international surgical community. The aim of the present study was to describe Danish surgeons' professional engagement in SM. METHODS: This was a descriptive cross-sectional study surveying all registered Danish surgeons who were members of the Danish Medical Association by May 2017...
September 2018: Danish Medical Journal
Mette Lund Madsen, Daniel Wæver, Lars Carl Borris, Lise Loft Nagel, Mads Henriksen, Rikke Thorninger, Jan Duedal Rölfing
INTRODUCTION: The objective of this study was to evaluate whether volar locking plating can restore the anatomical volar tilt of 12° and the anatomical length of the radius relative to the ulna. We retrospectively reviewed the radio-graphic outcome of distal radius fractures treated with two different first-generation locking plate systems; VariAx (Stryker) and Acu-Loc (Acumed). METHODS: Three independent observers evaluated radial volar tilt and ulnar variance (> 2 mm) on radiographs taken preoperatively, immediately after the operation and five weeks later...
August 2018: Danish Medical Journal
Finnur Mellemgaard, Rune B Strandby, Julie Blockmann, Steen C Kofoed, Lars B Svendsen, Michael P Achiam
INTRODUCTION: Single-operator cholangioscopy (SOC) is increasingly used for evaluation of the biliary tree following endoscopic retrograde cholangiopancreaticography (ERCP). This study aimed to determine the visual and histological success rates of SOC at a single Danish tertiary referral centre. METHODS: All patients undergoing SOC between 2008 and 2015 were retrospectively included from a prospectively maintained database. Patient characteristics and proced-ure-related variables were obtained from medical records...
August 2018: Danish Medical Journal
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