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Clinical and Translational Allergy

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https://www.readbyqxmd.com/read/28149501/is-fruit-and-vegetable-intake-associated-with-asthma-or-chronic-rhino-sinusitis-in-european-adults-results-from-the-global-allergy-and-asthma-network-of-excellence-ga-2-len-survey
#1
Vanessa Garcia-Larsen, Rhonda Arthur, James F Potts, Peter H Howarth, Matti Ahlström, Tari Haahtela, Carlos Loureiro, Ana Todo Bom, Grzegorz Brożek, Joanna Makowska, Marek L Kowalski, Trine Thilsing, Thomas Keil, Paolo M Matricardi, Kjell Torén, Thibaut van Zele, Claus Bachert, Barbara Rymarczyk, Christer Janson, Bertil Forsberg, Ewa Niżankowska-Mogilnicka, Peter G J Burney
BACKGROUND: Fruits and vegetables are rich in compounds with proposed antioxidant, anti-allergic and anti-inflammatory properties, which could contribute to reduce the prevalence of asthma and allergic diseases. OBJECTIVE: We investigated the association between asthma, and chronic rhino-sinusitis (CRS) with intake of fruits and vegetables in European adults. METHODS: A stratified random sample was drawn from the Global Allergy and Asthma Network of Excellence (GA(2)LEN) screening survey, in which 55,000 adults aged 15-75 answered a questionnaire on respiratory symptoms...
2017: Clinical and Translational Allergy
https://www.readbyqxmd.com/read/28078080/three-cases-of-anaphylaxis-following-injection-of-a-depot-corticosteroid-with-evidence-of-ige-sensitization-to-macrogols-rather-than-the-active-steroid
#2
Nicolaj Brandt, Lene H Garvey, Ulla Bindslev-Jensen, Henrik Fomsgaard Kjaer, Carsten Bindslev-Jensen, Charlotte G Mortz
We present three cases with anaphylaxis after injection of a depot corticosteroid. First, the steroid was suspected as the elicitor, but after evaluation the excipient macrogol was found to be the elicitor. One of the patients had reactions to several unrelated drugs. Increased awareness of anaphylaxis to excipients such as macrogols is needed, especially when allergy tests for the active drug is negative and in patients with a history of repeated anaphylaxis to seemingly unrelated drugs. To establish the correct diagnosis it is important to test with the exact formulation of the culprit drug, as well as all the ingredients including excipients...
2017: Clinical and Translational Allergy
https://www.readbyqxmd.com/read/28078079/looking-forward-to-new-targeted-treatments-for-chronic-spontaneous-urticaria
#3
REVIEW
Emek Kocatürk, Marcus Maurer, Martin Metz, Clive Grattan
The introduction of omalizumab to the management of chronic spontaneous urticaria (CSU) has markedly improved the therapeutic possibilities for both, patients and physicians dealing with this disabling disease. But there is still a hard core of patients who do not tolerate or benefit from existing therapies and who require effective treatment. Novel approaches include the use of currently available drugs off-licence, investigational drugs currently undergoing clinical trials and exploring the potential for therapies directed at pathophysiological targets in CSU...
2017: Clinical and Translational Allergy
https://www.readbyqxmd.com/read/28050247/aria-2016-care-pathways-implementing-emerging-technologies-for-predictive-medicine-in-rhinitis-and-asthma-across-the-life-cycle
#4
REVIEW
J Bousquet, P W Hellings, I Agache, A Bedbrook, C Bachert, K C Bergmann, M Bewick, C Bindslev-Jensen, S Bosnic-Anticevitch, C Bucca, D P Caimmi, P A M Camargos, G W Canonica, T Casale, N H Chavannes, A A Cruz, G De Carlo, R Dahl, P Demoly, P Devillier, J Fonseca, W J Fokkens, N A Guldemond, T Haahtela, M Illario, J Just, T Keil, L Klimek, P Kuna, D Larenas-Linnemann, M Morais-Almeida, J Mullol, R Murray, R Naclerio, R E O'Hehir, N G Papadopoulos, R Pawankar, P Potter, D Ryan, B Samolinski, H J Schunemann, A Sheikh, F E R Simons, C Stellato, A Todo-Bom, P V Tomazic, A Valiulis, E Valovirta, M T Ventura, M Wickman, I Young, A Yorgancioglu, T Zuberbier, W Aberer, C A Akdis, M Akdis, I Annesi-Maesano, J Ankri, I J Ansotegui, J M Anto, S Arnavielhe, A Asarnoj, H Arshad, F Avolio, I Baiardini, C Barbara, M Barbagallo, E D Bateman, B Beghé, E H Bel, K S Bennoor, M Benson, A Z Białoszewski, T Bieber, L Bjermer, H Blain, F Blasi, A L Boner, M Bonini, S Bonini, I Bosse, J Bouchard, L P Boulet, R Bourret, P J Bousquet, F Braido, A H Briggs, C E Brightling, J Brozek, R Buhl, C Bunu, E Burte, A Bush, F Caballero-Fonseca, M A Calderon, T Camuzat, V Cardona, P Carreiro-Martins, A M Carriazo, K H Carlsen, W Carr, A M Cepeda Sarabia, M Cesari, L Chatzi, R Chiron, T Chivato, E Chkhartishvili, A G Chuchalin, K F Chung, G Ciprandi, J Correia de Sousa, L Cox, G Crooks, A Custovic, S E Dahlen, U Darsow, T Dedeu, D Deleanu, J A Denburg, G De Vries, A Didier, A T Dinh-Xuan, D Dokic, H Douagui, G Dray, R Dubakiene, S R Durham, G Du Toit, M S Dykewicz, P Eklund, Y El-Gamal, E Ellers, R Emuzyte, J Farrell, A Fink Wagner, A Fiocchi, M Fletcher, F Forastiere, M Gaga, A Gamkrelidze, B Gemicioğlu, J E Gereda, R Gerth van Wick, S González Diaz, I Grisle, L Grouse, Z Gutter, M A Guzmán, B Hellquist-Dahl, J Heinrich, F Horak, J O' B Hourihane, M Humbert, M Hyland, G Iaccarino, E J Jares, C Jeandel, S L Johnston, G Joos, O Jonquet, K S Jung, M Jutel, I Kaidashev, M Khaitov, O Kalayci, A F Kalyoncu, P Kardas, P K Keith, M Kerkhof, H A M Kerstjens, N Khaltaev, M Kogevinas, V Kolek, G H Koppelman, M L Kowalski, M Kuitunen, I Kull, V Kvedariene, B Lambrecht, S Lau, D Laune, L T T Le, P Lieberman, B Lipworth, J Li, K C Lodrup Carlsen, R Louis, C Lupinek, W MacNee, Y Magar, A Magnan, B Mahboub, D Maier, I Majer, J Malva, P Manning, E De Manuel Keenoy, G D Marshall, M R Masjedi, E Mathieu-Dupas, M Maurer, S Mavale-Manuel, E Melén, E Melo-Gomes, E O Meltzer, J Mercier, H Merk, N Miculinic, F Mihaltan, B Milenkovic, J Millot-Keurinck, Y Mohammad, I Momas, R Mösges, A Muraro, L Namazova-Baranova, R Nadif, H Neffen, K Nekam, A Nieto, B Niggemann, L Nogueira-Silva, M Nogues, T D Nyembue, K Ohta, Y Okamoto, K Okubo, M Olive-Elias, S Ouedraogo, P Paggiaro, I Pali-Schöll, S Palkonen, P Panzner, A Papi, H S Park, G Passalacqua, S Pedersen, A M Pereira, O Pfaar, R Picard, B Pigearias, I Pin, D Plavec, W Pohl, T A Popov, F Portejoie, D Postma, L K Poulsen, D Price, K F Rabe, F Raciborski, G Roberts, C Robalo-Cordeiro, F Rodenas, L Rodriguez-Mañas, C Rolland, M Roman Rodriguez, A Romano, J Rosado-Pinto, N Rosario, M Rottem, M Sanchez-Borges, J Sastre-Dominguez, G K Scadding, N Scichilone, P Schmid-Grendelmeier, E Serrano, M Shields, V Siroux, J C Sisul, I Skrindo, H A Smit, D Solé, T Sooronbaev, O Spranger, R Stelmach, P J Sterk, T Strandberg, J Sunyer, C Thijs, M Triggiani, R Valenta, A Valero, M van Eerd, E van Ganse, M van Hague, O Vandenplas, L L Varona, B Vellas, G Vezzani, T Vazankari, G Viegi, T Vontetsianos, M Wagenmann, S Walker, D Y Wang, U Wahn, T Werfel, B Whalley, D M Williams, S Williams, N Wilson, J Wright, B P Yawn, P K Yiallouros, O M Yusuf, A Zaidi, H J Zar, M E Zernotti, L Zhang, N Zhong, M Zidarn
The Allergic Rhinitis and its Impact on Asthma (ARIA) initiative commenced during a World Health Organization workshop in 1999. The initial goals were (1) to propose a new allergic rhinitis classification, (2) to promote the concept of multi-morbidity in asthma and rhinitis and (3) to develop guidelines with all stakeholders that could be used globally for all countries and populations. ARIA-disseminated and implemented in over 70 countries globally-is now focusing on the implementation of emerging technologies for individualized and predictive medicine...
2016: Clinical and Translational Allergy
https://www.readbyqxmd.com/read/28031785/cross-reactive-ltp-sensitization-in-food-dependent-exercise-induced-urticaria-anaphylaxis-a-pilot-study-of-a-component-resolved-and-in-vitro-depletion-approach
#5
Diana Margarida Gonçalves Solha Pereira da Silva, Teresa Maria Silva Vieira, Ana Maria Alves Pereira, André Miguel Afonso de Sousa Moreira, José Luís Dias Delgado
BACKGROUND: Challenge tests for food-dependent exercise-induced anaphylaxis (FDEIA) carry some risk and have a high rate of false negatives. Our aim was to explore the usefulness of an in vitro immunodepletion assay and an allergen microarray test in the identification of IgE-mediated cross-reactive food allergens in patients with suspected FDEIA or food-dependent exercise-induced urticaria and panallergen sensitization. METHODS: Three patients with a history of food dependent exercise induced urticaria/anaphylaxis and food panallergen sensitization in whom a food-exercise challenge was not feasible were selected: a 25-year-old man with cholinergic urticaria who experienced generalized urticaria and angioedema during a soccer match after drinking a peach-based soft drink; a 19-year-old woman with allergic rhinitis and controlled asthma who experienced anaphylactic shock while playing soccer, having eaten walnuts in the previous 90 min; and a 57-year-old man with baker's asthma who experienced four episodes of anaphylaxis during exercise after ingesting wheat-containing food...
2016: Clinical and Translational Allergy
https://www.readbyqxmd.com/read/27999658/exploratory-analysis-of-cd63-and-cd203c-expression-in-basophils-from-hazelnut-sensitized-and-allergic-individuals
#6
Bianca Lötzsch, Sabine Dölle, Stefan Vieths, Margitta Worm
BACKGROUND: Sensitization to hazelnut (HN) is frequent and requires clarification to determine whether this sensitization is clinically relevant. The aim of this study was to investigate basophil activation profiles in HN-sensitized and allergic subjects. METHODS: Basophil activation was determined by flow cytometric analyses of CD63 and CD203c expression using several HN allergen concentrations. Depending on their clinical reaction pattern, an oral allergy symptom group (OAS, n = 20), a systemic reaction group (n = 12) and a sensitized group without clinical symptoms (n = 20) were identified...
2016: Clinical and Translational Allergy
https://www.readbyqxmd.com/read/27980722/immunoglobulin-free-light-chains-in-adult-atopic-dermatitis-patients-do-not-correlate-with-disease-severity
#7
J L Thijs, K Knipping, C A F Bruijnzeel-Koomen, J Garssen, M S de Bruin-Weller, D J Hijnen
BACKGROUND: Although total IgE levels have been proposed as a biomarker for disease severity in atopic dermatitis (AD) and are increased in the majority of AD patients, they do not correlate with disease severity during short-term follow-up. During the synthesis of immunoglobulins, free light chains (Ig-FLCs) are produced in excess over heavy chains. In comparison with IgE molecules, Ig-FLCs have a very short serum half-life. Therefore, Ig-FLCs might be more suitable as a biomarker for disease severity during follow-up...
2016: Clinical and Translational Allergy
https://www.readbyqxmd.com/read/27957322/a-mutually-beneficial-collaboration-between-the-european-academy-of-allergy-and-clinical-immunology-junior-members-and-clinical-and-translational-allergy
#8
EDITORIAL
Peter Valentin Tomazic, Anke Graessel, Diana Silva, Ibon Eguiluz-Gracia, George V Guibas, Clive Grattan, Jean Bousquet, Olympia Tsilochristou
The European Academy of Allergy and Clinical Immunology (EAACI) Junior Members (JM) comprise the largest EAACI section with around 4000 clinicians and scientists under 35 years of age working in the field of allergy and clinical immunology. The Junior Member collaboration with Clinical and Translational Allergy Journal is a mutually beneficial relationship providing Junior Members of EAACI with excellent opportunities to publish their work in the Journal, enhance their visibility in their respective field, and get involved with Journal-related activities and processes...
2016: Clinical and Translational Allergy
https://www.readbyqxmd.com/read/27895895/allergy-immunotherapy-across-the-life-cycle-to-promote-active-and-healthy-ageing-from-research-to-policies-an-airways-integrated-care-pathways-icps-programme-item-action-plan-b3-of-the-european-innovation-partnership-on-active-and-healthy-ageing-and-the-global
#9
REVIEW
M A Calderon, P Demoly, T Casale, C A Akdis, C Bachert, M Bewick, B M Bilò, B Bohle, S Bonini, A Bush, D P Caimmi, G W Canonica, V Cardona, A M Chiriac, L Cox, A Custovic, F De Blay, P Devillier, A Didier, G Di Lorenzo, G Du Toit, S R Durham, P Eng, A Fiocchi, A T Fox, R Gerth van Wijk, R M Gomez, T Haathela, S Halken, P W Hellings, L Jacobsen, J Just, L K Tanno, J Kleine-Tebbe, L Klimek, E F Knol, P Kuna, D E Larenas-Linnemann, A Linneberg, M Matricardi, H J Malling, R Moesges, J Mullol, A Muraro, N Papadopoulos, G Passalacqua, E Pastorello, O Pfaar, D Price, P Rodriguez Del Rio, R Ruëff, B Samolinski, G K Scadding, G Senti, M H Shamji, A Sheikh, J C Sisul, D Sole, G J Sturm, A Tabar, R Van Ree, M T Ventura, C Vidal, E M Varga, M Worm, T Zuberbier, J Bousquet
Allergic diseases often occur early in life and persist throughout life. This life-course perspective should be considered in allergen immunotherapy. In particular it is essential to understand whether this al treatment may be used in old age adults. The current paper was developed by a working group of AIRWAYS integrated care pathways for airways diseases, the model of chronic respiratory diseases of the European Innovation Partnership on active and healthy ageing (DG CONNECT and DG Santé). It considered (1) the political background, (2) the rationale for allergen immunotherapy across the life cycle, (3) the unmet needs for the treatment, in particular in preschool children and old age adults, (4) the strategic framework and the practical approach to synergize current initiatives in allergen immunotherapy, its mechanisms and the concept of active and healthy ageing...
2016: Clinical and Translational Allergy
https://www.readbyqxmd.com/read/27891215/hypothesis-may-e-cigarette-smoking-boost-the-allergic-epidemic
#10
EDITORIAL
Jean Bousquet, Claus Bachert, Laura Crotty Alexander, Frank T Leone
No abstract text is available yet for this article.
2016: Clinical and Translational Allergy
https://www.readbyqxmd.com/read/27826414/standardization-of-double-blind-placebo-controlled-food-challenge-with-soy-within-a-multicentre-trial
#11
R Treudler, A Franke, A Schmiedeknecht, B K Ballmer-Weber, M Worm, T Werfel, U Jappe, T Biedermann, J Schmitt, R Brehler, A Kleinheinz, J Kleine-Tebbe, H Brüning, F Ruëff, J Ring, J Saloga, K Schäkel, T Holzhauser, St Vieths, J C Simon
BACKGROUND: Multicentre trials investigating food allergies by double blind placebo controlled food challenges (DBPCFC) need standardized procedures, challenge meals and evaluation criteria. We aimed at developing a standardized approach for identifying patients with birch related soy allergy by means of DBPCFC to soy, including determination of threshold levels, in a multicentre setting. METHODS: Microbiologically stable soy challenge meals were composed of protein isolate with consistent Gly m 4 levels...
2016: Clinical and Translational Allergy
https://www.readbyqxmd.com/read/27733903/impaired-health-related-quality-of-life-in-adolescents-with-allergy-to-staple-foods
#12
Jennifer Lisa Penner Protudjer, Sven-Arne Jansson, Roelinde Middelveld, Eva Östblom, Sven-Erik Dahlén, Marianne Heibert Arnlind, Ulf Bengtsson, Ingrid Kallström-Bengtsson, Birgitta Marklund, Georgios Rentzos, Ann-Charlotte Sundqvist, Johanna Åkerström, Staffan Ahlstedt
BACKGROUND: Cow's milk, hen's egg and wheat are staple foods in a typical western diet. Despite the ubiquity of these foods, the impact of staple food allergy on health-related quality of life (HRQL) amongst adolescents is incompletely understood. The aims of this study were to make use of the Swedish version of EuroPrevall's disease-specific food allergy quality of life questionnaire-teenager form (FAQLQ-TF) and to investigate the association between objectively-diagnosed staple food allergy and HRQL amongst adolescents...
2016: Clinical and Translational Allergy
https://www.readbyqxmd.com/read/27688875/proficiency-testing-of-skin-prick-testers-as-part-of-a-quality-assurance-system
#13
Hans-Jørgen Malling, Pernille Allesen-Holm, Lisbeth Sys Karved, Lars K Poulsen
BACKGROUND: Skin prick test is an important diagnostic procedure in clinical allergy but documentation of the quality is often missing. METHODS: We describe a proficiency system to evaluate staff members in relation to the international recommended reproducibility in terms of coefficient of variation (CV < 40 %) and the linearity (coefficient of regression >0.85) based on blinded octuplicate histamine testing using histamine 3, 10, 30 and 100 mg/ml. RESULTS: Fourteen trained allergy nurses participated in the proficiency testing...
2016: Clinical and Translational Allergy
https://www.readbyqxmd.com/read/27610217/cost-utility-analysis-of-the-sq-%C3%A2-hdm-slit-tablet-in-house-dust-mite-allergic-asthma-patients-in-a-german-setting
#14
J Hahn-Pedersen, M Worm, W Green, J Nørgaard Andreasen, M Taylor
BACKGROUND: Asthma affects an estimated 300 million people worldwide with the condition associated with significant healthcare utilisation costs and a large impact on patient quality of life. The SQ(®) HDM SLIT-tablet (ACARIZAX(®), Hørsholm, Denmark) is a sublingually administered allergy immunotherapy tablet for house dust mite allergic asthma and allergic rhinitis and has recently been licensed in Europe. OBJECTIVE: To assess the cost-effectiveness of ACARIZAX plus pharmacotherapy versus placebo plus pharmacotherapy in patients with house dust mite allergic asthma that is uncontrolled by inhaled corticosteroids, in a German setting...
2016: Clinical and Translational Allergy
https://www.readbyqxmd.com/read/27583128/a-qualitative-study-of-the-allergy-testing-experiences-views-and-preferences-of-adult-patients
#15
Clare E Brown, Christina J Jones, Laura Stuttaford, Annalee Robertson, Rabia S Rashid, Helen E Smith
BACKGROUND: Patients can be tested for IgE sensitivities with in vivo or in vitro testing, but patients' experiences of different allergy test modalities have not been studied. The objective of this study was to investigate adult patients' experiences, views and preferences for allergy testing, exploring skin prick testing and allergen-specific IgE testing. METHODS: A qualitative study of adults attending out-patients for investigation of a suspected allergy. A purposive, convenience sample identified participants and semi-structured interviews were conducted, face to face or by telephone...
2016: Clinical and Translational Allergy
https://www.readbyqxmd.com/read/27559467/body-mass-index-and-physical-activity-in-early-childhood-are-associated-with-atopic-sensitization-atopic-dermatitis-and-asthma-in-later-childhood
#16
Kristine Kjer Byberg, Geir Egil Eide, Michele R Forman, Pétur Benedikt Júlíusson, Knut Øymar
BACKGROUND: The results of studies on the associations of childhood excessive weight/obesity and physical activity with atopic sensitization and atopic diseases are inconsistent. We studied the associations of anthropometry and physical activity in childhood with atopic sensitization and atopic diseases in late childhood. METHODS: In a cohort study including cases exposed to preeclampsia during pregnancy and controls, anthropometry and physical activity were assessed at several ages in 617 children...
2016: Clinical and Translational Allergy
https://www.readbyqxmd.com/read/27540466/improvement-of-sleep-in-patients-with-chronic-idiopathic-spontaneous-urticaria-treated-with-omalizumab-results-of-three-randomized-double-blind-placebo-controlled-studies
#17
Ana M Gimenéz-Arnau, Sheldon Spector, Evgeniya Antonova, Benjamin Trzaskoma, Karin Rosén, Theodore A Omachi, Donald Stull, Maria-Magdalena Balp, Thomas Murphy
BACKGROUND: Patients with chronic idiopathic/spontaneous urticaria (CIU/CSU) report difficulty with sleep. METHODS: We examined the effect of omalizumab on sleep-related outcomes during 3-6 months omalizumab or placebo treatment and a 16-week follow-up period within three Phase III double-blind randomized placebo-controlled pivotal trials in CIU/CSU: ASTERIA I, ASTERIA II, and GLACIAL. Sleep quality was assessed in all three studies using sleep-related questions included in an electronic diary, the Chronic Urticaria Quality of Life Questionnaire, and the Medical Outcomes Study Sleep Scale...
2016: Clinical and Translational Allergy
https://www.readbyqxmd.com/read/27493721/different-risk-factor-patterns-for-adult-asthma-rhinitis-and-eczema-results-from-west-sweden-asthma-study
#18
Erik P Rönmark, Linda Ekerljung, Roxana Mincheva, Sigrid Sjölander, Stig Hagstad, Göran Wennergren, Eva Rönmark, Jan Lötvall, Bo Lundbäck
BACKGROUND: Atopic diseases including asthma, rhinitis and eczema have increased in the second half of the past century. This has been well studied among children and adolescents but with the exception of asthma to a much lesser extent in adults. The adult risk factor pattern of atopic diseases, in particular of eczema, and their relation to allergic sensitization are yet to be fully elucidated. Studies among adults that have compared the risk factor pattern for these conditions in the same material are very few...
2016: Clinical and Translational Allergy
https://www.readbyqxmd.com/read/27478588/scaling-up-strategies-of-the-chronic-respiratory-disease-programme-of-the-european-innovation-partnership-on-active-and-healthy-ageing-action-plan-b3-area-5
#19
REVIEW
J Bousquet, J Farrell, G Crooks, P Hellings, E H Bel, M Bewick, N H Chavannes, J Correia de Sousa, A A Cruz, T Haahtela, G Joos, N Khaltaev, J Malva, A Muraro, M Nogues, S Palkonen, S Pedersen, C Robalo-Cordeiro, B Samolinski, T Strandberg, A Valiulis, A Yorgancioglu, T Zuberbier, A Bedbrook, W Aberer, M Adachi, A Agusti, C A Akdis, M Akdis, J Ankri, A Alonso, I Annesi-Maesano, I J Ansotegui, J M Anto, S Arnavielhe, H Arshad, C Bai, I Baiardini, C Bachert, A K Baigenzhin, C Barbara, E D Bateman, B Beghé, A Ben Kheder, K S Bennoor, M Benson, K C Bergmann, T Bieber, C Bindslev-Jensen, L Bjermer, H Blain, F Blasi, A L Boner, M Bonini, S Bonini, S Bosnic-Anticevitch, L P Boulet, R Bourret, P J Bousquet, F Braido, A H Briggs, C E Brightling, J Brozek, R Buhl, P G Burney, A Bush, F Caballero-Fonseca, D Caimmi, M A Calderon, P M Calverley, P A M Camargos, G W Canonica, T Camuzat, K H Carlsen, W Carr, A Carriazo, T Casale, A M Cepeda Sarabia, L Chatzi, Y Z Chen, R Chiron, E Chkhartishvili, A G Chuchalin, K F Chung, G Ciprandi, I Cirule, L Cox, D J Costa, A Custovic, R Dahl, S E Dahlen, U Darsow, G De Carlo, F De Blay, T Dedeu, D Deleanu, E De Manuel Keenoy, P Demoly, J A Denburg, P Devillier, A Didier, A T Dinh-Xuan, R Djukanovic, D Dokic, H Douagui, G Dray, R Dubakiene, S R Durham, M S Dykewicz, Y El-Gamal, R Emuzyte, L M Fabbri, M Fletcher, A Fiocchi, A Fink Wagner, J Fonseca, W J Fokkens, F Forastiere, P Frith, M Gaga, A Gamkrelidze, J Garces, J Garcia-Aymerich, B Gemicioğlu, J E Gereda, S González Diaz, M Gotua, I Grisle, L Grouse, Z Gutter, M A Guzmán, L G Heaney, B Hellquist-Dahl, D Henderson, A Hendry, J Heinrich, D Heve, F Horak, J O' B Hourihane, P Howarth, M Humbert, M E Hyland, M Illario, J C Ivancevich, J R Jardim, E J Jares, C Jeandel, C Jenkins, S L Johnston, O Jonquet, K Julge, K S Jung, J Just, I Kaidashev, M R Kaitov, O Kalayci, A F Kalyoncu, T Keil, P K Keith, L Klimek, B Koffi N'Goran, V Kolek, G H Koppelman, M L Kowalski, I Kull, P Kuna, V Kvedariene, B Lambrecht, S Lau, D Larenas-Linnemann, D Laune, L T T Le, P Lieberman, B Lipworth, J Li, K Lodrup Carlsen, R Louis, W MacNee, Y Magard, A Magnan, B Mahboub, A Mair, I Majer, M J Makela, P Manning, S Mara, G D Marshall, M R Masjedi, P Matignon, M Maurer, S Mavale-Manuel, E Melén, E Melo-Gomes, E O Meltzer, A Menzies-Gow, H Merk, J P Michel, N Miculinic, F Mihaltan, B Milenkovic, G M Y Mohammad, M Molimard, I Momas, A Montilla-Santana, M Morais-Almeida, M Morgan, R Mösges, J Mullol, S Nafti, L Namazova-Baranova, R Naclerio, A Neou, H Neffen, K Nekam, B Niggemann, G Ninot, T D Nyembue, R E O'Hehir, K Ohta, Y Okamoto, K Okubo, S Ouedraogo, P Paggiaro, I Pali-Schöll, P Panzner, N Papadopoulos, A Papi, H S Park, G Passalacqua, I Pavord, R Pawankar, R Pengelly, O Pfaar, R Picard, B Pigearias, I Pin, D Plavec, D Poethig, W Pohl, T A Popov, F Portejoie, P Potter, D Postma, D Price, K F Rabe, F Raciborski, F Radier Pontal, S Repka-Ramirez, S Reitamo, S Rennard, F Rodenas, J Roberts, J Roca, L Rodriguez Mañas, C Rolland, M Roman Rodriguez, A Romano, J Rosado-Pinto, N Rosario, L Rosenwasser, M Rottem, D Ryan, M Sanchez-Borges, G K Scadding, H J Schunemann, E Serrano, P Schmid-Grendelmeier, H Schulz, A Sheikh, M Shields, N Siafakas, Y Sibille, T Similowski, F E R Simons, J C Sisul, I Skrindo, H A Smit, D Solé, T Sooronbaev, O Spranger, R Stelmach, P J Sterk, J Sunyer, C Thijs, T To, A Todo-Bom, M Triggiani, R Valenta, A L Valero, E Valia, E Valovirta, E Van Ganse, M van Hage, O Vandenplas, T Vasankari, B Vellas, J Vestbo, G Vezzani, P Vichyanond, G Viegi, C Vogelmeier, T Vontetsianos, M Wagenmann, B Wallaert, S Walker, D Y Wang, U Wahn, M Wickman, D M Williams, S Williams, J Wright, B P Yawn, P K Yiallouros, O M Yusuf, A Zaidi, H J Zar, M E Zernotti, L Zhang, N Zhong, M Zidarn, J Mercier
Action Plan B3 of the European Innovation Partnership on Active and Healthy Ageing (EIP on AHA) focuses on the integrated care of chronic diseases. Area 5 (Care Pathways) was initiated using chronic respiratory diseases as a model. The chronic respiratory disease action plan includes (1) AIRWAYS integrated care pathways (ICPs), (2) the joint initiative between the Reference site MACVIA-LR (Contre les MAladies Chroniques pour un VIeillissement Actif) and ARIA (Allergic Rhinitis and its Impact on Asthma), (3) Commitments for Action to the European Innovation Partnership on Active and Healthy Ageing and the AIRWAYS ICPs network...
2016: Clinical and Translational Allergy
https://www.readbyqxmd.com/read/27453775/atopic-dermatitis-prevention-in-children-following-maternal-probiotic-supplementation-does-not-appear-to-be-mediated-by-breast-milk-tslp-or-tgf-%C3%AE
#20
Melanie Rae Simpson, Anne Dorthea Bjerkenes Rø, Øystein Grimstad, Roar Johnsen, Ola Storrø, Torbjørn Øien
BACKGROUND: The Probiotics in Prevention of Allergy among Children in Trondheim (ProPACT) study, a randomised, placebo controlled trial, demonstrated that maternal supplementation with probiotic milk reduced the incidence of atopic dermatitis (AD) in infancy. The mechanisms behind this effect are incompletely understood and breast milk cytokines have been postulated as possible mediating factors. In this study we aimed to assess whether breast milk TLSP and TGF-β are affected by a maternal probiotic supplementation regime, and their contribution to the preventive effect of this regime on AD in the offspring...
2016: Clinical and Translational Allergy
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