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Annals of Laboratory Medicine

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https://www.readbyqxmd.com/read/29611395/mutation-analysis-of-x-linked-sideroblastic-anemia-in-a-12-month-old-boy-by-massively-parallel-sequencing
#1
LETTER
Hui Jin Yu, Young Ju Lee, Jae Won Shim, Deok Soo Kim, Jung Yeon Shim, Moon Soo Park, Hee Yeon Woo, Hyosoon Park, Hye Lim Jung, Min Jung Kwon
No abstract text is available yet for this article.
July 2018: Annals of Laboratory Medicine
https://www.readbyqxmd.com/read/29611394/extended-red-blood-cell-genotyping-to-investigate-immunohematology-problems
#2
LETTER
Kyung Hwa Shin, Hyun Ji Lee, Kyung Hee Park, Bae Mi Hye, Chulhun L Chang, Hyung Hoi Kim
No abstract text is available yet for this article.
July 2018: Annals of Laboratory Medicine
https://www.readbyqxmd.com/read/29611393/prevalence-of-plasmid-mediated-quinolone-resistance-genes-among-escherichia-coli-in-the-gut-of-healthy-people-in-fuzhou-china
#3
LETTER
Bin Li, Yao Chen, Zhiyun Wu, Zhichang Zhao, Juan Wu, Yingping Cao
No abstract text is available yet for this article.
July 2018: Annals of Laboratory Medicine
https://www.readbyqxmd.com/read/29611392/multiple-intraabdominal-abscesses-caused-by-mycoplasma-hominis-infection-following-simultaneous-pancreas-kidney-transplantation
#4
LETTER
Yumiko Okumura, Toshiki Kajihara, Yumiko Koba, Makoto Onodera, Toshinori Hara, Hiroyuki Tahara, Hideki Ohdan, Hiroki Ohge, Michiya Yokozaki, Motoyuki Sugai
No abstract text is available yet for this article.
July 2018: Annals of Laboratory Medicine
https://www.readbyqxmd.com/read/29611391/rapid-identification-of-bla-imp-1-and-bla-imp-6-by-multiplex-amplification-refractory-mutation-system-pcr
#5
LETTER
Akiyo Nakano, Ryuichi Nakano, Yuki Suzuki, Kyoichi Saito, Kei Kasahara, Shiro Endo, Hisakazu Yano
No abstract text is available yet for this article.
July 2018: Annals of Laboratory Medicine
https://www.readbyqxmd.com/read/29611390/necessity-of-reticulocyte-calibration-for-more-accurate-and-precise-results
#6
Yong Kwan Lim, Hyun Young Chi, Mi Kyung Lee, Hye Ryoun Kim
No abstract text is available yet for this article.
July 2018: Annals of Laboratory Medicine
https://www.readbyqxmd.com/read/29611389/effects-of-cold-agglutinin-on-the-accuracy-of-complete-blood-count-results-and-optimal-sample-pretreatment-protocols-for-eliminating-such-effects
#7
LETTER
John Hoon Rim, Myung Hee Chang, Joowon Oh, Heon Yung Gee, Jeong Ho Kim, Jongha Yoo
No abstract text is available yet for this article.
July 2018: Annals of Laboratory Medicine
https://www.readbyqxmd.com/read/29611388/phenotypic-and-genomic-characterization-of-ampc-producing-klebsiella-pneumoniae-from-korea
#8
Mattia Palmieri, Stephane Schicklin, Andreu Coello Pelegrin, Sonia Chatellier, Christine Franceschi, Caroline Mirande, Yeon Joon Park, Alex van Belkum
The prevalence of multidrug-resistant gram-negative bacteria has continuously increased over the past few years; bacterial strains producing AmpC β-lactamases and/or extended-spectrum β-lactamases (ESBLs) are of particular concern. We combined high-resolution whole genome sequencing and phenotypic data to elucidate the mechanisms of resistance to cephamycin and β-lactamase in Korean Klebsiella pneumoniae strains, in which no AmpC-encoding genes were detected by PCR. We identified several genes that alone or in combination can potentially explain the resistance phenotype...
July 2018: Annals of Laboratory Medicine
https://www.readbyqxmd.com/read/29611387/flow-cytometric-analysis-of-hna-2-expression-and-phenotypes-among-thai-blood-donors
#9
Oytip Nathalang, Kanokpol Siriphanthong, Sawang Petvises, Nichapa Jeumjanya
BACKGROUND: Antibodies specific to human neutrophil antigen (HNA), especially HNA-2, are implicated in various conditions, including neonatal alloimmune neutropenia, febrile non-hemolytic transfusion reactions, and transfusion-related acute lung injury. The distribution of the HNA-2 phenotype frequencies in the Thai population remains unknown. This study aimed to investigate HNA-2 phenotype frequencies in Thai blood donors and to compare the relationships of sex and age with HNA-2 expression...
July 2018: Annals of Laboratory Medicine
https://www.readbyqxmd.com/read/29611386/comparison-of-four-automated-carcinoembryonic-antigen-immunoassays-advia-centaur-xp-architect-i2000sr-elecsys-e170-and-unicel-dxi800
#10
Joonhong Park, Seungok Lee, Yeongsic Kim, Aeran Choi, Hyeyoung Lee, Jihyang Lim, Yonggoo Kim, Kyungja Han, Eun Jee Oh
BACKGROUND: Carcinoembryonic antigen (CEA) is one of the tumor markers available for evaluating disease progression status after initial therapy and monitoring subsequent treatment modalities in colorectal, gastrointestinal, lung, and breast carcinoma. We evaluated the correlations and differences between widely used, automated CEA immunoassays at four different medical laboratories. METHODS: In total, 393 serum samples with CEA ranging from 3.0 to 1,000 ng/mL were analyzed on ADVIA Centaur XP (Siemens Diagnostics, Tarrytown, NY, USA), ARCHITECT i2000sr (Abbott Diagnostics, Abbott Park, IL, USA), Elecsys E170 (Roche Diagnostics, Indianapolis, IN, USA), and Unicel DxI800 (Beckman Coulter, Fullerton, CA, USA), and the results were compared...
July 2018: Annals of Laboratory Medicine
https://www.readbyqxmd.com/read/29611385/diagnosis-of-liver-fibrosis-with-wisteria-floribunda-agglutinin-positive-mac-2-binding-protein-wfa-m2bp-among-chronic-hepatitis-b-patients
#11
Dong Wook Jekarl, Hyunyu Choi, Seungok Lee, Jung Hyun Kwon, Sung Won Lee, Hein Yu, Myungshin Kim, Yonggoo Kim, Pil Soo Sung, Seung Kew Yoon
BACKGROUND: Wisteria floribunda agglutinin-positive Mac-2 binding protein (WFA-M2BP) is a protein with altered glycosylation that reacts with lectin, and was recently identified as a useful non-invasive biomarker for the diagnosis of liver fibrosis in patients with hepatitis C virus infection.This study aimed to evaluate the diagnostic efficacy of WFA-M2BP for liver fibrosis in the context of hepatitis B virus (HBV). METHODS: We enrolled 151 patients infected with HBV...
July 2018: Annals of Laboratory Medicine
https://www.readbyqxmd.com/read/29611384/allergen-microarrays-for-in-vitro-diagnostics-of-allergies-comparison-with-immunocap-and-advansure
#12
Hyunjin Jeon, Joo Hyun Jung, Yoonji Kim, Youngeun Kwon, Seon Tae Kim
BACKGROUND: In vitro detection of the allergen-specific IgE antibody (sIgE) is a useful tool for the diagnosis and treatment of allergies. Although multiple simultaneous allergen tests offer simple and low-cost screening methods, these platforms also have limitations with respect to multiplexibility and analytical performance. As an alternative assay platform, we developed and validated a microarray using allergen extracts that we termed "GOLD" chip. METHODS: Serum samples of 150 allergic rhinitis patients were used in the study, and the diagnostic performance of the microarray was compared with that of AdvanSure (LG Life Sciences, Daejun, Korea) and ImmunoCAP (Phadia, Uppsala, Sweden)...
July 2018: Annals of Laboratory Medicine
https://www.readbyqxmd.com/read/29611383/usefulness-of-enhanced-liver-fibrosis-glycosylation-isomer-of-mac-2-binding-protein-galectin-3-and-soluble-suppression-of-tumorigenicity-2-for-assessing-liver-fibrosis-in-chronic-liver-diseases
#13
Hee Won Moon, Mikyoung Park, Mina Hur, Hanah Kim, Won Hyeok Choe, Yeo Min Yun
BACKGROUND: Liver biopsies have been partially replaced by noninvasive methods for assessing liver fibrosis. We explored the usefulness of four novel biomarkers, enhanced liver fibrosis (ELF), glycosylation isomer of Mac-2 binding protein (M2BPGi), galectin-3, and soluble suppression of tumorigenicity 2 (sST2), in association with liver fibrosis. METHODS: ELF, M2BPGi, galectin-3, and sST2 were assayed in 173 patients with chronic liver diseases. The results were analyzed according to fibrosis grade (F0/1, F2, and F3/4) by transient elastography (TE)...
July 2018: Annals of Laboratory Medicine
https://www.readbyqxmd.com/read/29611382/recent-increase-in-the-incidence-of-tem-135-%C3%AE-lactamase-harboring-neisseria-gonorrhoeae-in-korea
#14
John Hoon Rim, Hyunsoo Kim, Hyukmin Lee, Dongeun Yong, Seok Hoon Jeong, Kyungwon Lee
BACKGROUND: We investigated the molecular epidemiological characteristics and antimicrobial susceptibility pattern of penicillinase-producing Neisseria gonorrhoeae (PPNG) isolates to monitor the change in distribution of bla(TEM) in Korea. METHODS: We collected 804 PPNG isolates from diverse hospitals and clinics mainly located in Seoul, Korea, over a period of 11 years (2005-2015). Isolate susceptibility to seven antimicrobials was determined using the agar dilution test...
July 2018: Annals of Laboratory Medicine
https://www.readbyqxmd.com/read/29611381/determining-genotypic-drug-resistance-by-ion-semiconductor-sequencing-with-the-ion-ampliseq%C3%A2-tb-panel-in-multidrug-resistant-mycobacterium-tuberculosis-isolates
#15
Joonhong Park, So Youn Shin, Kyungjong Kim, Kuhn Park, Soyoung Shin, Chunhwa Ihm
BACKGROUND: We examined the feasibility of a full-length gene analysis for the drug resistance-related genes inhA, katG, rpoB, pncA, rpsL, embB, eis, and gyrA using ion semiconductor next-generation sequencing (NGS) and compared the results with those obtained from conventional phenotypic drug susceptibility testing (DST) in multidrug-resistant Mycobacterium tuberculosis (MDR-TB) isolates. METHODS: We extracted genomic DNA from 30 pure MDR-TB isolates with antibiotic susceptibility profiles confirmed by phenotypic DST for isoniazid (INH), rifampin (RIF), ethambutol (EMB), pyrazinamide (PZA), amikacin (AMK), kanamycin (KM), streptomycin (SM), and fluoroquinolones (FQs) including ofloxacin, moxifloxacin, and levofloxacin...
July 2018: Annals of Laboratory Medicine
https://www.readbyqxmd.com/read/29611380/galectin-3-reflects-the-echocardiographic-grades-of-left-ventricular-diastolic-dysfunction
#16
Uzair Ansari, Michael Behnes, Julia Hoffmann, Michele Natale, Christian Fastner, Ibrahim El-Battrawy, Jonas Rusnak, Seung Hyun Kim, Siegfried Lang, Ursula Hoffmann, Thomas Bertsch, Martin Borggrefe, Ibrahim Akin
BACKGROUND: The level of Galectin-3 (Gal-3) protein purportedly reflects an ongoing cardiac fibrotic process and has been associated with ventricular remodeling, which is instrumental in the development of heart failure with preserved ejection fraction (HFpEF) syndrome. The aim of this study was to investigate the potential use of Gal-3 in improved characterization of the grades of diastolic dysfunction as defined by echocardiography. METHODS: Seventy HFpEF patients undergoing routine echocardiography were prospectively enrolled in the present monocentric study...
July 2018: Annals of Laboratory Medicine
https://www.readbyqxmd.com/read/29611379/gata1-expression-in-bcr-abl1-negative-myeloproliferative-neoplasms
#17
Naery Yang, Sholhui Park, Min Sun Cho, Miae Lee, Ki Sook Hong, Yeung Chul Mun, Chu Myong Seong, Hee Jin Huh, Jungwon Huh
BACKGROUND: This study aimed to determine GATA1 expression levels to better characterize subgroups in BCR/ABL1-negative myeloproliferative neoplasms (MPNs). METHODS: This study enrolled 49 patients diagnosed as having BCR/ABL1-negative MPN on the basis of the 2016 World Health Organization classification : nine polycythemia vera (PV), 17 essential thrombocythemia (ET), 12 prefibrotic primary myelofibrosis (prePMF), and 11 overt primary myelofibrosis (PMF). Relevant clinical and laboratory data were retrieved from the medical records...
July 2018: Annals of Laboratory Medicine
https://www.readbyqxmd.com/read/29611378/principles-of-genetic-counseling-in-the-era-of-next-generation-sequencing
#18
REVIEW
Mina Yang, Jong Won Kim
Traditional genetic counseling has focused on the target gene and its natural progress with respect to disease risk. Next-generation sequencing (NGS) can produce information on several genetic variants simultaneously, with different functions and consequences for each. Accordingly, determining the status of the patient or consultant and interpreting sequencing results from many genes can largely increase the complexity of genetic counseling. Moreover, the current environment of big data that can be readily shared via the internet and a ubiquitous network provides many different avenues for which a consultant must handle the traditional principle of genetic counseling in different ways...
July 2018: Annals of Laboratory Medicine
https://www.readbyqxmd.com/read/29611377/mac-2-binding-protein-glycosylation-isomer-emerging-non-invasive-serum-marker-for-liver-fibrosis
#19
EDITORIAL
Sun Young Cho, Mina Hur
No abstract text is available yet for this article.
July 2018: Annals of Laboratory Medicine
https://www.readbyqxmd.com/read/29401569/erratum-increasing-incidence-of-listeriosis-and-infection-associated-clinical-outcomes
#20
(no author information available yet)
This corrects the article on p. 102 in vol. 38, PMID: 29214753.
May 2018: Annals of Laboratory Medicine
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