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Annals of Laboratory Medicine

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https://www.readbyqxmd.com/read/29214768/congenital-analbuminemia-in-unrelated-algerian-and-turkish-families-is-caused-by-the-same-molecular-defect-in-the-albumin-gene
#1
LETTER
Gianluca Caridi, Abdelbasset Maout, Reha Artan, Monica Campagnoli, Francesca Lugani, Mohamed El Amine Abada, Ersin Sayar, Monica Galliano, Lorenzo Minchiotti
No abstract text is available yet for this article.
March 2018: Annals of Laboratory Medicine
https://www.readbyqxmd.com/read/29214767/catheter-related-bloodstream-infection-due-to-lodderomyces-elongisporus-in-a-patient-with-lung-cancer
#2
LETTER
Hye Young Lee, Soo Jung Kim, Duckhee Kim, Jeonghyun Jang, Heungsup Sung, Mi Na Kim, Chang Min Choi
No abstract text is available yet for this article.
March 2018: Annals of Laboratory Medicine
https://www.readbyqxmd.com/read/29214766/abrupt-increase-in-rate-of-imipenem-resistance-in-acinetobacter-baumannii-complex-strains-isolated-from-general-hospitals-in-korea-and-correlation-with-carbapenem-administration-during-2002-2013
#3
Young Ah Kim, Yoon Soo Park, Taemi Youk, Hyukmin Lee, Kyungwon Lee
No abstract text is available yet for this article.
March 2018: Annals of Laboratory Medicine
https://www.readbyqxmd.com/read/29214765/correlation-of-aminoglycoside-consumption-and-amikacin-or-gentamicin-resistant-pseudomonas-aeruginosa-in-long-term-nationwide-analysis-is-antibiotic-cycling-an-effective-policy-for-reducing-antimicrobial-resistance
#4
Young Ah Kim, Yoon Soo Park, Taemi Youk, Hyukmin Lee, Kyungwon Lee
No abstract text is available yet for this article.
March 2018: Annals of Laboratory Medicine
https://www.readbyqxmd.com/read/29214764/bone-marrow-involvement-of-epstein-barr-virus-positive-large-b-cell-lymphoma-in-a-patient-with-angioimmunoblastic-t-cell-lymphoma
#5
LETTER
Taegeun Lee, Borae G Park, Eunkyoung You, Young Uk Cho, Seongsoo Jang, Sun Mi Lee, Cheolwon Suh, Chan Jeoung Park
No abstract text is available yet for this article.
March 2018: Annals of Laboratory Medicine
https://www.readbyqxmd.com/read/29214763/a-novel-e8a2bcr-abl1-fusion-transcript-without-insertion-sequence-in-a-patient-with-chronic-myeloid-leukemia
#6
LETTER
Caibao Jin, Xiaojian Zhu, Min Xiao, Songya Liu, Xian Liu, Jingjing Liu, Xiuwen Xu, Shujuan Yi, Li Meng
No abstract text is available yet for this article.
March 2018: Annals of Laboratory Medicine
https://www.readbyqxmd.com/read/29214762/incidental-identification-of-plasmodium-vivax-during-routine-complete-blood-count-analysis-using-the-unicel-dxh-800
#7
LETTER
Soyoung Shin, Sun Hee Park, Joonhong Park
No abstract text is available yet for this article.
March 2018: Annals of Laboratory Medicine
https://www.readbyqxmd.com/read/29214761/clinicopathological-characteristics-of-hyperdiploidy-with-high-risk-cytogenetics-in-multiple-myeloma
#8
Naery Yang, Yeung Chul Mun, Chu Myong Seong, Hee Jin Huh, Jungwon Huh
In multiple myeloma (MM), hyperdiploidy (HD) is known to impart longer overall survival. However, it is unclear whether coexistent HD ameliorates the adverse effects of known high-risk cytogenetics in MM patients. To address this issue, we investigated the clinicopathological characteristics of HD with high-risk cytogenetics in MM. Ninety-seven patients with MM were included in the study. For metaphase cytogenetics (MC), unstimulated cells from bone marrow aspirates were cultured for either 24 or 48 hours. To detect HD by interphase fluorescence in situ hybridization (iFISH), we assessed trisomies of chromosomes 5, 7, 9, 11, 15, and 17...
March 2018: Annals of Laboratory Medicine
https://www.readbyqxmd.com/read/29214760/prevalence-of-blaz-gene-and-performance-of-phenotypic-tests-to-detect-penicillinase-in-staphylococcus-aureus-isolates-from-japan
#9
Yoshiko Takayama, Takashi Tanaka, Koko Oikawa, Naoki Fukano, Mieko Goto, Takashi Takahashi
Guidelines recommend that clinical laboratories perform phenotypic tests (nitrocefin-based test and penicillin 10-U [P10] or 1-U [P1] zone edge tests) to detect penicillinase in Staphylococcus aureus isolates. This study aimed to assess the prevalence of blaZ encoding penicillinase and perform various phenotypic tests in S. aureus isolates from Japan. We prospectively collected 200 methicillin-susceptible S. aureus isolates from June 2015 to January 2016 and performed six phenotypic tests (nitrocefin-based test, P10 zone edge test/P10 diffusion test, penicillin 2-U [P2] zone edge test/P2 diffusion test, and cloverleaf test) on each sample...
March 2018: Annals of Laboratory Medicine
https://www.readbyqxmd.com/read/29214759/clinical-implications-of-quantitative-jak2-v617f-analysis-using-droplet-digital-pcr-in-myeloproliferative-neoplasms
#10
Eunyoung Lee, Kyoung Joo Lee, Hyein Park, Jin Young Chung, Mi Na Lee, Myung Hee Chang, Jongha Yoo, Hyewon Lee, Sun Young Kong, Hyeon Seok Eom
BACKGROUND: JAK2 V617F is the most common mutation in myeloproliferative neoplasms (MPNs) and is a major diagnostic criterion. Mutation quantification is useful for classifying patients with MPN into subgroups and for prognostic prediction. Droplet digital PCR (ddPCR) can provide accurate and reproducible quantitative analysis of DNA. This study was designed to verify the correlation of ddPCR with pyrosequencing results in the diagnosis of MPN and to investigate clinical implications of the mutational burden...
March 2018: Annals of Laboratory Medicine
https://www.readbyqxmd.com/read/29214758/comparison-of-four-human-papillomavirus-genotyping-methods-next-generation-sequencing-inno-lipa-electrochemical-dna-chip-and-nested-pcr
#11
Pornjarim Nilyanimit, Jira Chansaenroj, Witthaya Poomipak, Kesmanee Praianantathavorn, Sunchai Payungporn, Yong Poovorawan
BACKGROUND: Human papillomavirus (HPV) infection causes cervical cancer, thus necessitating early detection by screening. Rapid and accurate HPV genotyping is crucial both for the assessment of patients with HPV infection and for surveillance studies. METHODS: Fifty-eight cervicovaginal samples were tested for HPV genotypes using four methods in parallel: nested-PCR followed by conventional sequencing, INNO-LiPA, electrochemical DNA chip, and next-generation sequencing (NGS)...
March 2018: Annals of Laboratory Medicine
https://www.readbyqxmd.com/read/29214757/clinical-and-cytogenetic-profiles-of-rhabdomyosarcoma-with-bone-marrow-involvement-in-korean-children-a-15-year-single-institution-experience
#12
Dong Hyun Lee, Chan Jeoung Park, Seongsoo Jang, Young Uk Cho, Jong Jin Seo, Ho Joon Im, Kyung Nam Koh, Kyung Ja Cho, Joon Seon Song, Eul Ju Seo
BACKGROUND: Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in children. Alveolar RMS (ARMS) is characterized by FOXO1-related chromosomal translocations that result in a poorer clinical outcome compared with embryonal RMS (ERMS). Because the chromosomal features of RMS have not been comprehensively defined, we analyzed the clinical and laboratory data of childhood RMS patients and determined the clinical significance of chromosomal abnormalities in the bone marrow. METHODS: Fifty-one Korean patients with RMS <18 years of age treated between 2001 and 2015 were enrolled in this study...
March 2018: Annals of Laboratory Medicine
https://www.readbyqxmd.com/read/29214756/serum-cytokine-profile-in-patients-with-chronic-rhinosinusitis-with-nasal-polyposis-infected-by-aspergillus-flavus
#13
Gargi Rai, Mohammad Ahmad Ansari, Sajad Ahmad Dar, Shyama Datt, Neelima Gupta, Sonal Sharma, Shafiul Haque, Vishnampettai Ganapathysubramanian Ramachandran, Arpeeta Mazumdar, Shivprakash Rudramurthy, Arunaloke Chakrabarti, Shukla Das
BACKGROUND: Fungi, especially Aspergillus flavus, can cause chronic rhinosinusitis with nasal polyposis and modulate host innate immune components. The objective of this study was to examine the serum levels of T helper (Th) cell subset Th1, Th2, and Th17 cytokines and total IgE in patients having chronic rhinosinusitis with nasal polyposis and Aspergillus flavus infection. METHODS: A case-control study including 40 patients with chronic rhinosinusitis with nasal polyposis and 20 healthy controls was conducted...
March 2018: Annals of Laboratory Medicine
https://www.readbyqxmd.com/read/29214755/comparative-evaluation-of-the-loop-mediated-isothermal-amplification-assay-for-detecting-pulmonary-tuberculosis
#14
Chang Ki Kim, Eun A Cho, Dong Mi Shin, Sung Won Choi, So Youn Shin
BACKGROUND: Early detection of tuberculosis (TB) is challenging in resource-poor settings because of limited accessibility to molecular diagnostics. The aim of this study was to evaluate the performance of the loop-mediated isothermal amplification kit (TB-LAMP) for TB diagnosis compared with conventional and molecular tests. METHODS: A total of 290 consecutive sputum samples were collected from May till September, 2015. All samples were processed using the N-Acetyl-L-cysteine (NALC) NaOH method and tested by smear microscopy, solid and liquid culture, real-time PCR, and TB-LAMP...
March 2018: Annals of Laboratory Medicine
https://www.readbyqxmd.com/read/29214754/utility-of-conventional-culture-and-maldi-tof-ms-for-identification-of-microbial-communities-in-bronchoalveolar-lavage-fluid-in-comparison-with-the-gs-junior-next-generation-sequencing-system
#15
Ji Yeon Sung, Younjee Hwang, Mi Hwa Shin, Moo Suk Park, Sang Hoon Lee, Dongeun Yong, Kyungwon Lee
BACKGROUND: Diverse microbiota exist in the lower respiratory tract. Although next generation sequencing (NGS) is the most widely used microbiome analysis technique, it is difficult to implement NGS in clinical microbiology laboratories. Therefore, we evaluated the performance of conventional culture methods together with matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) in identifying microbiota in bronchoalveolar lavage (BAL) fluid. METHODS: BAL fluid samples (n=27) were obtained from patients undergoing diagnostic bronchoscopy for lung mass evaluation...
March 2018: Annals of Laboratory Medicine
https://www.readbyqxmd.com/read/29214753/increasing-incidence-of-listeriosis-and-infection-associated-clinical-outcomes
#16
Min Hyuk Choi, Yu Jin Park, Myungsook Kim, Young Hee Seo, Young Ah Kim, Jun Yong Choi, Dongeun Yong, Seok Hoon Jeong, Kyungwon Lee
BACKGROUND: Listeriosis caused by Listeria monocytogenes has a high case-fatality rate (CFR) of approximately 20% to 30%. An increasing incidence of listeriosis has been reported in many countries recently. We investigated the annual incidence, clinical characteristics, and outcomes of listeriosis at three different hospitals in Korea and evaluated the effects of appropriate empiric antimicrobial treatments on patient outcomes. METHODS: We retrospectively collected the data of all culture-positive cases of human listeriosis from three hospitals of different sizes in Korea during 2006-2016 and calculated the annual number of cases and incidence per 100,000 admissions...
March 2018: Annals of Laboratory Medicine
https://www.readbyqxmd.com/read/29214752/evaluation-of-sflt-1-plgf-ratio-for-predicting-and-improving-clinical-management-of-pre-eclampsia-experience-in-a-specialized-perinatal-care-center
#17
Hélène Caillon, Cécile Tardif, Erwan Dumontet, Norbert Winer, Damien Masson
BACKGROUND: Management of pregnant women at high risk of pre-eclampsia (PE) requires frequent monitoring, with referral to specialized perinatal care centers. Reliable tests are necessary to improve prediction of PE and related complications and to assess disease severity and progression. An imbalance in two biomarkers, soluble fms-like tyrosine kinase 1 (sFlt-1) and placental growth factor (PlGF), is involved in PE pathogenesis. The sFlt-1 to PlGF ratio is increased in pregnant women before the onset of PE...
March 2018: Annals of Laboratory Medicine
https://www.readbyqxmd.com/read/29214751/multi-center-performance-evaluations-of-tacrolimus-and-cyclosporine-electrochemiluminescence-immunoassays-in-the-asia-pacific-region
#18
Xuzhen Qin, Jianzhong Rui, Yong Xia, Hong Mu, Sang Hoon Song, Raja Elina Raja Aziddin, Gabrielle Miles, Yuli Sun, Sail Chun
BACKGROUND: The immunosuppressant drugs (ISDs), tacrolimus and cyclosporine, are vital for solid organ transplant patients to prevent rejection. However, toxicity is a concern, and absorption is highly variable across patients; therefore, ISD levels need to be precisely monitored. In the Asia-Pacific (APAC) region, tacrolimus and cyclosporine concentrations are typically measured using immunoassays. The objective of this study was to assess the analytical performance of Roche Elecsystacrolimus and cyclosporinee electrochemiluminescence immunoassays (ECLIAs)...
March 2018: Annals of Laboratory Medicine
https://www.readbyqxmd.com/read/29071828/intactness-of-medical-nonsterile-gloves-on-use-of-alcohol-disinfectants
#19
Jiyoung Chang, Tae Dong Jeong, Seungok Lee, Yeongsic Kim, Jehoon Lee, Hae Kyung Lee, Hi Jeong Kwon
No abstract text is available yet for this article.
January 2018: Annals of Laboratory Medicine
https://www.readbyqxmd.com/read/29071827/identification-of-homozygous-likely-pathogenic-variant-of-aldh3a2-in-a-korean-boy-with-sj%C3%A3-gren-larsson-syndrome
#20
LETTER
Je Yeon Kim, Shin Hye Kim, Mi Jung Park, Soung Hee Kim, Woo Ho Cho, Jin Choi, Chang Seok Ki, Su Jeong You
No abstract text is available yet for this article.
January 2018: Annals of Laboratory Medicine
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