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Annals of Laboratory Medicine

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https://www.readbyqxmd.com/read/29797824/pcm1-jak2-fusion-in-a-patient-with-acute-myeloid-leukemia
#1
LETTER
Jong Mi Lee, Jaewoong Lee, Eunhee Han, Myungshin Kim, Yonggoo Kim, Kyungja Han, Hee Je Kim
No abstract text is available yet for this article.
September 2018: Annals of Laboratory Medicine
https://www.readbyqxmd.com/read/29797823/first-case-of-pasteurella-multocida-pneumonic-bacteremia-in-korea
#2
LETTER
Jinho Jang, Sang Ha Kim, Gilsung Yoo, Gyu Yel Hwang, Young Uh, Kap Jun Yoon
No abstract text is available yet for this article.
September 2018: Annals of Laboratory Medicine
https://www.readbyqxmd.com/read/29797822/performance-of-microflex-lt-biotyper-and-vitek-ms-for-routine-identification-of-yeasts
#3
LETTER
Jung Hyun Byun, A Reum Yu, Myung Sook Kim, Kyungwon Lee
No abstract text is available yet for this article.
September 2018: Annals of Laboratory Medicine
https://www.readbyqxmd.com/read/29797821/performance-evaluation-of-the-preanalytic-module-of-the-acl-top-750-hemostasis-lab-system
#4
LETTER
Woo Jae Kwoun, Jeong Yeal Ahn, Pil Whan Park, Yiel Hea Seo, Kyung Hee Kim, Ja Young Seo, Ji Hun Jeong, Hwan Tae Lee
No abstract text is available yet for this article.
September 2018: Annals of Laboratory Medicine
https://www.readbyqxmd.com/read/29797820/the-2016-who-versus-2008-who-criteria-for-the-diagnosis-of-chronic-myelomonocytic-leukemia
#5
Yeonsook Moon, Mi Hyang Kim, Hye Ryoun Kim, Jeong Yeal Ahn, Jungwon Huh, Ji Young Huh, Jae Ho Han, Joon Seong Park, Sung Ran Cho
The 2016 WHO diagnostic criteria for chronic myelomonocytic leukemia (CMML) require both absolute and relative monocytosis (≥1×10⁹/L and ≥10% of white blood cell counts) in peripheral blood. Moreover, myeloproliferative neoplasm (MPN) features in bone marrow and/or MPN-associated mutations tend to support MPN with monocytosis rather than CMML. We assessed the impact of the 2016 WHO criteria on CMML diagnosis, compared with the 2008 WHO criteria, through a retrospective review of the medical records of 38 CMML patients diagnosed according to the 2008 WHO classification...
September 2018: Annals of Laboratory Medicine
https://www.readbyqxmd.com/read/29797819/chromosomal-microarray-with-clinical-diagnostic-utility-in-children-with-developmental-delay-or-intellectual-disability
#6
Jin Sook Lee, Hee Hwang, Soo Yeon Kim, Ki Joong Kim, Jin Sun Choi, Mi Jung Woo, Young Min Choi, Jong Kwan Jun, Byung Chan Lim, Jong Hee Chae
BACKGROUND: Chromosomal microarray (CMA) testing is a first-tier test for patients with developmental delay, autism, or congenital anomalies. It increases diagnostic yield for patients with developmental delay or intellectual disability. In some countries, including Korea, CMA testing is not yet implemented in clinical practice. We assessed the diagnostic utility of CMA testing in a large cohort of patients with developmental delay or intellectual disability in Korea. METHODS: We conducted a genome-wide microarray analysis of 649 consecutive patients with developmental delay or intellectual disability at the Seoul National University Children's Hospital...
September 2018: Annals of Laboratory Medicine
https://www.readbyqxmd.com/read/29797818/the-role-of-the-signal-to-cutoff-ratio-in-automated-anti-hcv-chemiluminescent-immunoassays-by-referring-to-the-nucleic-acid-amplification-test-and-the-recombinant-immunoblot-assay
#7
Moon Suk Choi, Kyunghoon Lee, Yun Ji Hong, Eun Young Song, Dal Sik Kim, Junghan Song
BACKGROUND: Following discontinuation of the recombinant immunoblot assay (RIBA), the only available supplementary test for the detection of hepatitis C virus (HCV) is the nucleic acid amplification test (NAAT). However, the NAAT does not adequately detect past HCV. Consequently, it is hard to distinguish between past HCV infection and biological false positivity with an anti-HCV result alone. We assessed the diagnostic performance of two immunoassays: the ARCHITECT anti-HCV chemiluminescent microparticle immunoassay (CMIA; Abbott Diagnostics, Wiesbaden, Germany) and the Access HCV Ab PLUS chemiluminescent immunoassay (CIA; Bio-Rad, Marnes-la-Coquette, France)...
September 2018: Annals of Laboratory Medicine
https://www.readbyqxmd.com/read/29797817/diagnostic-performance-and-comparative-evaluation-of-the-architect-liaison-and-platelia-epstein-barr-virus-antibody-assays
#8
Younhee Park, Borae G Park, Jihye Ha, Hyon Suk Kim
BACKGROUND: Epstein-Barr Virus (EBV) is one of the most prevalent causes of viral infection in humans. EBV infection stage (acute, past, or absent infection) is typically determined using a combination of assays that detect EBV-specific markers, such as IgG and IgM antibodies against the EBV viral capsid antigen (VCA) and IgG antibodies against the EBV nuclear antigen (EBNA). We compared the diagnostic performance and agreement of results between three commercial EBV antibody assays using an EBV performance panel (SeraCare Life Science, Milford, MA, USA) as a reference...
September 2018: Annals of Laboratory Medicine
https://www.readbyqxmd.com/read/29797816/clinical-impact-of-pre-transplant-antibodies-against-angiotensin-ii-type-i-receptor-and-major-histocompatibility-complex-class-i-related-chain-a-in-kidney-transplant-patients
#9
Ji Won Min, Hyeyoung Lee, Bum Soon Choi, Cheol Whee Park, Chul Woo Yang, Yong Soo Kim, Yeong Jin Choi, Eun Jee Oh, Byung Ha Chung
BACKGROUND: Evidence of antibody-mediated injury in the absence of donor-specific HLA antibodies (HLA-DSA) has recently emerged, suggesting a role of antibodies in targeting non-HLA antigens expressed on renal allograft tissue. However, the clinical significance of pre-transplant non-HLA antibodies remains unclear. We compared the histological and clinical impact of pre-transplant HLA-DSA and non-HLA antibodies, especially angiotensin II type I receptor (anti-AT1R) and MHC class I-related chain A (anti-MICA), in kidney transplant patients...
September 2018: Annals of Laboratory Medicine
https://www.readbyqxmd.com/read/29797815/asymmetrical-dimethylarginine-levels-in-hepatitis-b-virus-positive-patients
#10
Faruk Karakecili, Aytekin Cikman, Merve Aydin, Baris Gulhan
BACKGROUND: High asymmetrical dimethylarginine (ADMA) levels have been associated with endothelial dysfunction and contribute to the development of several diseases. However, data on the relationship between hepatitis B virus (HBV) and ADMA are limited. The aim of our study was to explore the relationship between ADMA and HBV by comparing the ADMA levels in patients with chronic active hepatitis B (CHB), inactive HBV carriers (carriers), and healthy volunteers (controls). METHODS: The participants were divided into three groups: 90 patients with CHB, 90 HBV carriers, and 90 controls...
September 2018: Annals of Laboratory Medicine
https://www.readbyqxmd.com/read/29797814/evaluation-of-the-luminex-aries-hsv-1-2-assay-and-comparison-with-the-ftd-neuro-9-and-in-house-real-time-pcr-assays-for-detecting-herpes-simplex-viruses
#11
Chun Kiat Lee, Chean Nee Chai, Sharah Mae Capinpin, Alynn Ang, Sau Yoke Ng, Peak Ling Lee, Christopher Wai Siong Ng, Gabriel Yan, Hong Kai Lee, Lily Lily Chiu, Roland Jureen, Benedict Yan, Tze Ping Loh
BACKGROUND: Human herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2) are responsible for a plethora of human diseases, of which cutaneous and mucocutaneous infections are the most prevalent. In its most severe form, HSV infection can cause meningitis/encephalitis. We compared the Luminex ARIES HSV 1&2 assay (Luminex Corp., Austin, TX, USA), an automated sample-to-result molecular solution, to two non-automated HSV DNA assays. METHODS: A total of 116 artificial controls were used to determine the analytical performance of the ARIES assay...
September 2018: Annals of Laboratory Medicine
https://www.readbyqxmd.com/read/29797813/postprandial-lipid-concentrations-and-daytime-biological-variation-of-lipids-in-a-healthy-chinese-population
#12
Dagan Yang, Qian Cai, Xinglun Qi, Yunxian Zhou
BACKGROUND: Several latest guidelines and consensus statements from Europe and the United States specify that there is no need for fasting prior to routine lipid tests. However, the latest Chinese guidelines still recommend fasting tests owing to a lack of local evidence. This study aimed to investigate postprandial lipid concentrations and daytime biological variation of lipids in a healthy Chinese population. METHODS: Venous blood samples were collected from 41 ostensibly healthy Chinese volunteers at five time points during the day (06:30, 09:00, 12:00, 15:00, and 18:30)...
September 2018: Annals of Laboratory Medicine
https://www.readbyqxmd.com/read/29797812/plasma-neutrophil-gelatinase-associated-lipocalin-as-a-predictor-of-renal-parenchymal-involvement-in-infants-with-febrile-urinary-tract-infection-a-preliminary-study
#13
Bo Ae Yun, Eun Mi Yang, Chan Jong Kim
BACKGROUND: Urinary tract infection (UTI) is the most common bacterial infection in infants. Renal parenchymal involvement is an important prognostic factor; however, early detection of parenchymal involvement in UTI may be difficult during infancy. This study aimed to assess whether a recently established biomarker of UTI, neutrophil gelatinase-associated lipocalin (NGAL), can serve as a useful marker for the detection of cortical defects (CD) and to determine the appropriate diagnostic cut-off value of NGAL in infants with febrile UTI...
September 2018: Annals of Laboratory Medicine
https://www.readbyqxmd.com/read/29797811/proposed-imprecision-quality-goals-for-urinary-albumin-creatinine-ratio
#14
Dae Hyun Ko, Sung Woo Lee, Jungwon Hyun, Hyun Soo Kim, Min Jeong Park, Dong Hoon Shin
BACKGROUND: The urinary albumin/creatinine ratio (ACR) is an important indicator of albuminuria. We aimed to estimate ACR uncertainty and its impact on test results and proposed imprecision quality goals based on the estimated uncertainty. METHODS: The combined ACR uncertainty was calculated using the individual uncertainties of urinary albumin and creatinine. ACR confidence intervals (CIs) were estimated based on the expanded uncertainty. When the CI contained the ACR category boundary (30 or 300 mg/g), the cases were considered ambiguous...
September 2018: Annals of Laboratory Medicine
https://www.readbyqxmd.com/read/29797810/platelet-function-analyzer-200-p2y-results-are-predictive-of-the-risk-of-major-adverse-cardiac-events-in-korean-patients-receiving-clopidogrel-therapy-following-acute-coronary-syndrome
#15
Hyeon Ho Lim, Shuhua Li, Gyu Dae An, Kwang Sook Woo, Kyeong Hee Kim, Jeong Man Kim, Moo Hyun Kim, Jin Yeong Han
BACKGROUND: Clopidogrel is one of the most commonly used anti-platelet agents in cardiovascular diseases. We analyzed the relationship between the platelet function analyzer (PFA)-200 P2Y (INNOVANCE PFA-200 System, Siemens Healthcare, Germany) results and occurrence of major adverse cardiac events (MACEs) in Korean patients with recent-onset acute coronary syndrome (ACS) taking clopidogrel. METHODS: Between August 2013 and June 2016, we prospectively enrolled 106 patients with recent-onset ACS who had been treated with clopidogrel...
September 2018: Annals of Laboratory Medicine
https://www.readbyqxmd.com/read/29797809/reducing-test-utilization-in-hospital-settings-a-narrative-review
#16
REVIEW
Renuka S Bindraban, Maarten J Ten Berg, Christiana A Naaktgeboren, Mark H H Kramer, Wouter W Van Solinge, Prabath W B Nanayakkara
BACKGROUND: Studies addressing the appropriateness of laboratory testing have revealed approximately 20% overutilization. We conducted a narrative review to (1) describe current interventions aimed at reducing unnecessary laboratory testing, specifically in hospital settings, and (2) provide estimates of their efficacy in reducing test order volume and improving patient-related clinical outcomes. METHODS: The PubMed, Embase, Scopus, Web of Science, and Canadian Agency for Drugs and Technologies in Health-Health Technology Assessment databases were searched for studies describing the effects of interventions aimed at reducing unnecessary laboratory tests...
September 2018: Annals of Laboratory Medicine
https://www.readbyqxmd.com/read/29797808/rejuvenating-aged-hematopoietic-stem-cells-through-improvement-of-mitochondrial-function
#17
REVIEW
James Moon, Hye Ran Kim, Myung Geun Shin
Mitochondria are the powerhouses of the cell as well as the primary site of hematopoiesis, which also occurs in the cytoplasm. Hematopoietic stem cells (HSCs) are characterized by a very high turnover rate, and are thus considered to be relatively free from the age-related insults generated by mitochondria. However, HSCs are also subject to these age-related insults, including the incidence of myeloid proliferative diseases, marrow failure, hematopoietic neoplasms, and deterioration of the adaptive human immune system...
September 2018: Annals of Laboratory Medicine
https://www.readbyqxmd.com/read/29797807/neutrophil-gelatinase-associated-lipocalin-as-a-promising-novel-biomarker-for-early-detection-of-kidney-injury
#18
EDITORIAL
Sun Young Cho, Mina Hur
No abstract text is available yet for this article.
September 2018: Annals of Laboratory Medicine
https://www.readbyqxmd.com/read/29611395/mutation-analysis-of-x-linked-sideroblastic-anemia-in-a-12-month-old-boy-by-massively-parallel-sequencing
#19
LETTER
Hui Jin Yu, Young Ju Lee, Jae Won Shim, Deok Soo Kim, Jung Yeon Shim, Moon Soo Park, Hee Yeon Woo, Hyosoon Park, Hye Lim Jung, Min Jung Kwon
No abstract text is available yet for this article.
July 2018: Annals of Laboratory Medicine
https://www.readbyqxmd.com/read/29611394/extended-red-blood-cell-genotyping-to-investigate-immunohematology-problems
#20
LETTER
Kyung Hwa Shin, Hyun Ji Lee, Kyung Hee Park, Bae Mi Hye, Chulhun L Chang, Hyung Hoi Kim
No abstract text is available yet for this article.
July 2018: Annals of Laboratory Medicine
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