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Annals of Laboratory Medicine

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https://www.readbyqxmd.com/read/29071828/intactness-of-medical-nonsterile-gloves-on-use-of-alcohol-disinfectants
#1
Jiyoung Chang, Tae Dong Jeong, Seungok Lee, Yeongsic Kim, Jehoon Lee, Hae Kyung Lee, Hi Jeong Kwon
No abstract text is available yet for this article.
January 2018: Annals of Laboratory Medicine
https://www.readbyqxmd.com/read/29071827/identification-of-homozygous-likely-pathogenic-variant-of-aldh3a2-in-a-korean-boy-with-sj%C3%A3-gren-larsson-syndrome
#2
LETTER
Je Yeon Kim, Shin Hye Kim, Mi Jung Park, Soung Hee Kim, Woo Ho Cho, Jin Choi, Chang Seok Ki, Su Jeong You
No abstract text is available yet for this article.
January 2018: Annals of Laboratory Medicine
https://www.readbyqxmd.com/read/29071826/deletion-of-20p13-and-duplication-of-20p13p12-3-in-a-patient-with-delayed-speech-and-development
#3
LETTER
Soon Sung Kwon, Jieun Kim, Saeam Shin, Seung Tae Lee, Kyung A Lee, Jong Rak Choi
No abstract text is available yet for this article.
January 2018: Annals of Laboratory Medicine
https://www.readbyqxmd.com/read/29071825/a-case-of-anti-reticulin-antibody-positivity-in-metachronous-double-primary-cancer
#4
LETTER
Ki Na Kim, La He Jearn, Think You Kim
No abstract text is available yet for this article.
January 2018: Annals of Laboratory Medicine
https://www.readbyqxmd.com/read/29071824/polymicrobial-anaerobic-bacteremia-caused-by-butyricimonas-virosa-and-brachyspira-pilosicoli-in-a-patient-with-peritonitis-following-intestinal-perforation
#5
LETTER
Yoshihiko Ogawa, Masatoshi Sato, Takaya Yamashita, Ryuichi Nakano, Satoshi Mochizuki, Kei Kasahara, Hisakazu Yano, Keiichi Mikasa
No abstract text is available yet for this article.
January 2018: Annals of Laboratory Medicine
https://www.readbyqxmd.com/read/29071823/effect-of-accreditation-on-the-accuracy-of-diagnostic-hematologic-tests-standard-deviation-index-analysis
#6
Young Ahn Yoon, Mi Ae Jang, Ji Sung Lee, Won Ki Min, Kye Chul Kwon, Yong Wha Lee, You Kyoung Lee
No abstract text is available yet for this article.
January 2018: Annals of Laboratory Medicine
https://www.readbyqxmd.com/read/29071822/molecular-and-cytogenetic-studies-in-a-child-with-burkitt-lymphoma-and-ataxia-telangiectasia-syndrome-harboring-myc-overexpression-and-partial-trisomy-8
#7
Mariana T De Souza, Gabriela Vera-Lozada, Moneeb Othman, Teresinha J Marques-Salles, Luciana W Pinto, Moisés M da Rocha, Soraia Rouxinol, Thomas Liehr, Raul C Ribeiro, Rocio Hassan, Maria Luiza M Silva
No abstract text is available yet for this article.
January 2018: Annals of Laboratory Medicine
https://www.readbyqxmd.com/read/29071821/chinese-pediatric-reference-intervals-for-serum-cortisol-on-immulite-2000
#8
Ling Li Wang, Li Yue Zhang, Hui Yan Wang, Huai Kai Wen, Hong Qun Tao, Xiao Wei Zhao
Clinical interpretation of the test results for cortisol based on continuous reference intervals with appropriate partitions improves pediatric diagnosis; however, these values are available only for Caucasians. To develop the pediatric reference intervals for Chinese population, we examined the serum cortisol levels in 1,143 healthy Chinese children aged 4-18 years (566 boys and 577 girls), using an IMMULITE 2000 Immunoassay System (Siemens Healthcare GmbH). Phlebotomy was performed at 7-9 a.m. for 284 boys and 287 girls and at 1-3 p...
January 2018: Annals of Laboratory Medicine
https://www.readbyqxmd.com/read/29071820/application-of-multigene-panel-sequencing-in-patients-with-prolonged-rate-corrected-qt-interval-and-no-pathogenic-variants-detected-in-kcnq1-kcnh2-and-scn5a
#9
Soo Hyun Seo, So Yeon Kim, Sung Im Cho, Hyunwoong Park, Seungjun Lee, Jong Moon Choi, Man Jin Kim, Jee Soo Lee, Kyung Jin Ahn, Mi Kyoung Song, Eun Jung Bae, Sung Sup Park, Moon Woo Seong
Long QT syndrome (LQTS) is an inherited cardiac disease characterized by a prolonged heart rate-corrected QT (QTc) interval. We investigated the genetic causes in patients with prolonged QTc intervals who were negative for pathogenic variants in three major LQTS-related genes (KCNQ1, KCNH2, and SCN5A). Molecular genetic testing was performed using a panel including 13 LQTS-related genes and 67 additional genes implicated in other cardiac diseases. Overall, putative genetic causes of prolonged QTc interval were identified in three of the 30 patients (10%)...
January 2018: Annals of Laboratory Medicine
https://www.readbyqxmd.com/read/29071819/is-it-necessary-to-repeat-fecal-occult-blood-tests-with-borderline-results-for-colorectal-cancer-screening
#10
Eunyoung Lee, Yangsoon Lee
The fecal immunochemical test (FIT) is the initial non-invasive investigation of choice for population-based colorectal cancer (CRC) screening. We evaluated the positivity rate in repeated tests using the same fecal specimen that showed borderline results in the FIT. A total of 6,465 patients were tested with the FIT in a tertiary-care hospital from July to December 2016. FIT was done using OC-Sensor PLEDIA (Eiken Chemical Co., Tokyo, Japan). Among 6,465 patients, 364 (5.6%) patients showed a positive FIT result of over 20 μg Hb/g feces...
January 2018: Annals of Laboratory Medicine
https://www.readbyqxmd.com/read/29071818/evaluation-of-allplex-respiratory-panel-1-2-3-multiplex-real-time-pcr-assays-for-the-detection-of-respiratory-viruses-with-influenza-a-virus-subtyping
#11
Jaehyeon Lee, Hye Soo Lee, Yong Gon Cho, Sam Im Choi, Dal Sik Kim
The Allplex Respiratory Panel 1/2/3 (All16) is a multiplex PCR assay for detecting 16 respiratory viruses with influenza A virus (FluA) subtyping, and the first clinical assay based on multiple detection temperatures. We compared the results between All16 and Anyplex II RV16 (Any16) in 426 clinical samples. Samples showing discrepancies between the two tests were further tested using monoplex PCR. FluA subtyping based on the hemagglutinin type results of All16, which yielded H1, H3, and non-H1/H3, was compared with the results of the BioFire FilmArray respiratory panel...
January 2018: Annals of Laboratory Medicine
https://www.readbyqxmd.com/read/29071817/urinary-ykl-40-as-a-candidate-biomarker-for-febrile-urinary-tract-infection-in-young-children
#12
Hyun Hee Kim, Mi Hae Chung, Joong Hyun Bin, Kyoung Soon Cho, Juyoung Lee, Jin Soon Suh
BACKGROUND: Given that YKL-40 is a known marker of inflammation, we sought to determine its association with urinary tract infection (UTI) in febrile children. METHODS: In total, 44 children aged 0 to 24 months with febrile UTI and 35 age- and sex-matched controls with fever from other causes were enrolled in the study. ELISA was performed to determine the level of YKL-40 in urine collected from each child. RESULTS: The ratio of urinary YKL-40 to creatinine (Cr) was higher in the children with a UTI than in the controls (P<0...
January 2018: Annals of Laboratory Medicine
https://www.readbyqxmd.com/read/29071816/application-of-multiplex-ligation-dependent-probe-amplification-assay-for-genotyping-major-blood-group-systems-including-del-variants-in-the-d-negative-korean-population
#13
Banseok Kim, Seung Tae Lee, Sinyoung Kim, Jong Rak Choi, Hyun Ok Kim
BACKGROUND: The DEL blood type, a very weak D variant, is a major concern in the field of transfusion medicine because of its potential to cause anti-D alloimmunization. We investigated the molecular basis of serologically D-negative phenotypes, including the DEL type, and the distribution of other blood group systems in the Korean population using the recently developed multiplex ligation-dependent probe amplification (MLPA) assay. METHODS: Blood group genotyping using the MLPA assay and RhCE phenotyping were performed on randomly selected 95 D-negative red blood cell products...
January 2018: Annals of Laboratory Medicine
https://www.readbyqxmd.com/read/29071815/comparison-of-singleplex-specific-ige-detection-immunoassays-immunocap-phadia-250-and-immulite-2000-3gallergy
#14
Kyung Hee Park, Jongsun Lee, Da Woon Sim, Sang Chul Lee
BACKGROUND: The identification of clinically meaningful specific immunoglobulin E (sIgE) is important for the diagnosis and management of allergic diseases. Various in vitro sIgE detection methods are available worldwide. Depending on the number of antigens that can be tested simultaneously, there are two representative methods: singleplex and multiplex. Singleplex sIgE detection is mainly provided by Thermo Fisher (ImmunoCAP) and Siemens (Immulite). This study aimed to compare the diagnostic agreement of two singleplex sIgE detection assays...
January 2018: Annals of Laboratory Medicine
https://www.readbyqxmd.com/read/29071814/extensively-drug-resistant-escherichia-coli-sequence-type-1642-carrying-an-incx3-plasmid-containing-the-blakpc-2-gene-associated-with-transposon-tn4401a
#15
Seri Jeong, Jung Ok Kim, Eun Jeong Yoon, Il Kwon Bae, Woonhyoung Lee, Hyukmin Lee, Yongjung Park, Kyungwon Lee, Seok Hoon Jeong
BACKGROUND: Extensively drug-resistant (XDR) Enterobacteriaceae carrying the bla(KPC) gene have emerged as a major global therapeutic concern. The purpose of this study was to analyze the complete sequences of plasmids from KPC-2 carbapenemase-producing XDR Escherichia coli sequence type (ST) 1642 isolates. METHODS: We performed antimicrobial susceptibility testing, PCR, multilocus sequence typing (MLST), and whole-genome sequencing to characterize the plasmid-mediated KPC-2-producing E...
January 2018: Annals of Laboratory Medicine
https://www.readbyqxmd.com/read/29071813/serum-macrophage-migration-inhibitory-factor-as-a-biomarker-of-active-pulmonary-tuberculosis
#16
Zhong Bo Shang, Jun Wang, Shou Gang Kuai, Yin Yin Zhang, Qin Fang Ou, Hao Pei, Li Hua Huang
BACKGROUND: Macrophage migration inhibitory factor (MIF), a pro-inflammatory cytokine with chemokine-like functions, has been shown to play a central role in several acute and chronic inflammatory diseases. However, limited information is available regarding the use of MIF as an inflammatory pathway marker in patients with tuberculosis. This study aimed to investigate the association of MIF with IFN-γ and TNF-α in active pulmonary tuberculosis (APTB) following anti-tuberculosis treatment...
January 2018: Annals of Laboratory Medicine
https://www.readbyqxmd.com/read/29071812/cell-free-dna-in-oncology-gearing-up-for-clinic
#17
REVIEW
Bryan C Ulrich, Cloud P Paweletz
In the past several years, interest in the clinical utility of cell-free DNA as a noninvasive cancer biomarker has grown rapidly. Success in the development of plasma genotyping assays and other liquid biopsy assays has widened the scope of cell-free DNA use in research and the clinic. Already approved by the US Food and Drug Administration in the narrow context of epidermal growth factor receptor-mutated non-small cell lung cancer, plasma genotyping assays are currently being investigated in a wide array of clinical settings and modalities...
January 2018: Annals of Laboratory Medicine
https://www.readbyqxmd.com/read/28841002/phenotype-of-a-patient-with-a-1p36-11-p35-3-interstitial-deletion-encompassing-the-ahdc1
#18
LETTER
Hae Yeon Park, Myungshin Kim, Woori Jang, Dae Hyun Jang
No abstract text is available yet for this article.
November 2017: Annals of Laboratory Medicine
https://www.readbyqxmd.com/read/28841001/a-case-of-antley-bixler-syndrome-with-a-novel-likely-pathogenic-variant-c-529g-c-in-the-por-gene
#19
LETTER
Jongwon Oh, Ju Sun Song, Jong Eun Park, Shin Yi Jang, Chang Seok Ki, Duk Kyung Kim
No abstract text is available yet for this article.
November 2017: Annals of Laboratory Medicine
https://www.readbyqxmd.com/read/28841000/first-case-of-echinocandin-resistant-candida-albicans-in-korea
#20
LETTER
Min Seung Park, Jong Eun Park, Dong Joon Song, Hee Jae Huh, Silvia Park, Cheol In Kang, Jong Hee Shin, Nam Yong Lee
No abstract text is available yet for this article.
November 2017: Annals of Laboratory Medicine
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