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Journal of Natural Science, Biology, and Medicine

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https://www.readbyqxmd.com/read/28250690/aortoiliac-reconstruction-in-the-setting-of-in-stent-restenosis
#1
H S Natraj Setty, T R Raghu, B C Srinivas, C M Nagesh, Babu Reddy, Jayashree Kharge, B K Geetha, B N Krishnamurthy, Shivanand Patil, C N Manjunath
Complex iliac artery obstructions, particularly bilateral stenosis or total iliac artery occlusions, are usually treated with aortofemoral or aortobifemoral graft surgery. However, surgical treatment is associated with 3% mortality rate and significant morbidity such as intestinal ischemia, spinal cord injury, and ureteral damage. Percutaneous interventions of aortic bifurcation offer a promising alternative to surgery with potentially lower morbidity and mortality risk. We report a case of peripheral artery disease who had underwent right transfemoral iliac angioplasty with femoropopliteal bypass presented again with bilateral lower limb ischemia, who was successfully treated with stent implantation with the kissing balloon technique...
January 2017: Journal of Natural Science, Biology, and Medicine
https://www.readbyqxmd.com/read/28250689/amiodarone-induced-loculated-pleural-effusion-without-pulmonary-parenchymal-involvement-a-case-report-and-literature-review
#2
Amer Hawatmeh, Mohammad Thawabi, Ashraf Jmeian, Hamid Shaaban, Fayez Shamoon
Amiodarone is an extremely effective antiarrhythmic drug that is known to cause many adverse effects such as pulmonary, thyroid, and liver toxicities. Of these, pulmonary toxicity is most serious. Pulmonary toxicity can present as interstitial pneumonitis, organizing pneumonia, pulmonary nodules and masses, and very rarely pleural effusions. We present a case of a 73-year-old male who presented with progressive exertional dyspnea, nonproductive cough, generalized fatigue, and weakness. He was found to have multiorgan toxicity secondary to long-term treatment with high doses of amiodarone...
January 2017: Journal of Natural Science, Biology, and Medicine
https://www.readbyqxmd.com/read/28250688/profile-of-cervical-cancer-patients-attending-tertiary-care-hospitals-of-mangalore-karnataka-a-4-year-retrospective-study
#3
Aadhya Sharma, Vaman Kulkarni, Unnikrishnan Bhaskaran, Meher Singha, Saad Mujtahedi, Anshul Chatrath, Mallika Sridhar, Rekha Thapar, P Prasanna Mithra, Nithin Kumar, Ramesh Holla, B B Darshan, Avinash Kumar
OBJECTIVES: To describe the sociodemographic characteristics and clinical profile of women presenting with cervical carcinoma and to identify factors associated with the timing of presentation and prognosis. MATERIALS AND METHODS: A record-based descriptive study was carried out from 1(st) February to 31(st) March 2014 at Tertiary Care Hospitals of Mangalore. The study population included women who were diagnosed with cervical carcinoma from January 1, 2010 to December 31, 2013...
January 2017: Journal of Natural Science, Biology, and Medicine
https://www.readbyqxmd.com/read/28250687/novel-hydroxamates-potentiated-in-vitro-activity-of-fluconazole-against-candida-albicans
#4
Maneesh Paul-Satyaseela, Periasamy Hariharan, Thirunavukkarasu Bharani, Jonathan S Franklyne, Thangapazham Selvakumar, Kuppusamy Bharathimohan, Chenniappan Vinoth Kumar, Virendra Kachhadia, Shridhar Narayanan, Sridharan Rajagopal, Gopalan Balasubramanian
A set of 12 novel hydroxamate compounds (NHCs), structurally designed as inhibitors of histone deacetylase (HDAC) enzyme, were synthesized at our facility. These were adamantane derivatives with N-hydroxyacetamide as pharmacophore, and each of these compounds was tested for potentiating activity on fluconazole. The concentration of fluconazole which completely inhibited (concentration of complete inhibition [CCI]) the growth of Candida albicans ATCC 90028 and C. albicans ATCC 64550 was determined by micro-dilution method in the absence and presence of NHCs...
January 2017: Journal of Natural Science, Biology, and Medicine
https://www.readbyqxmd.com/read/28250686/prevalence-of-tuberculosis-among-children-in-north-sudan-are-we-only-seeing-the-tip-of-the-iceberg
#5
Wadie M Elmadhooun, Elmuntasir Taha Salah, Sufian K Noor, Sarra O Bushara, Ekhlas O Ahmed, Hamdan Mustafa, Amel A Sulaiman, Mohamed H Ahmed
INTRODUCTION: Tuberculosis (TB) is a significant cause of morbidity and mortality among children. The vague symptoms, the uncertain diagnostic tests and lack of adequate awareness among families all contributed in masking the actual prevalence of the disease. The objective of this study was to describe the epidemiology of childhood TB in River Nile State (RNS), North Sudan. METHODS: All registered cases of TB aged 15 years and below, at the 13 management units in RNS during 3 years, 2011-2013 were included...
January 2017: Journal of Natural Science, Biology, and Medicine
https://www.readbyqxmd.com/read/28250685/evaluation-of-ischemia-modified-albumin-oxidative-stress-and-antioxidant-status-in-acute-ischemic-stroke-patients
#6
Itishri Jena, Sarthak Ranjan Nayak, Sudeshna Behera, Bratati Singh, Subhashree Ray, Diptimayee Jena, Santosh Singh, Subrat Kumar Sahoo
BACKGROUND: Oxidative stress is characterized by increased production of reactive oxygen species resulting in the generation of lipid peroxides such as malondialdehyde (MDA). The studies have shown that ischemia-modified albumin (IMA), which has widely been studied as a marker of ischemia, also increases as result of oxidative stress. Hence, the current study was done to evaluate the serum MDA, IMA along with serum uric acid, and albumin, which are important metabolic antioxidants. MATERIALS AND METHODS: Fifty patients with acute ischemic stroke were taken as cases and compared with 50 age- and sex-matched controls...
January 2017: Journal of Natural Science, Biology, and Medicine
https://www.readbyqxmd.com/read/28250684/acute-st-segment-elevation-myocardial-infarction-the-prognostic-importance-of-lead-augmented-vector-right-and-leads-v7-v9
#7
Veeresh Patil Hebbal, Huliyurdurga Srinivasasetty Natraj Setty, Cholenahalli Manjunath Sathvik, Vikram Patil, Sarthak Sahoo, Cholenahalli Nanjappa Manjunath
BACKGROUND: Acute myocardial infarction (MI) is associated with high mortality and among survivors have high morbidity. Electrocardiogram (ECG), a cost-effective and easily available, has traditionally been used not only just for diagnosis of MI but also for culprit vessel recognition and for prognostication. However, the role of lead augmented vector right (aVR) and leads V7-V9 in acute MI are often neglected in clinical practice. We studied the role of lead aVR and leads V7-V9 in ST-elevation MI (STEMI) patients...
January 2017: Journal of Natural Science, Biology, and Medicine
https://www.readbyqxmd.com/read/28250683/evaluation-of-oxidative-stress-in-chronic-periodontitis-patients-following-systemic-antioxidant-supplementation-a-clinical-and-biochemical-study
#8
Manasa Ambati, Koduganti Rekha Rani, Panthula Veerendranath Reddy, Jammula Suryaprasanna, Rajashree Dasari, Himabindu Gireddy
CONTEXT: Oxidative stress is associated with the pathogenesis of many systemic diseases including chronic periodontitis. Periodontal pathogen activated neutrophils liberate the reactive oxygen species (ROS), which causes the destruction of periodontal tissues. Antioxidants modulate the ROS production and inhibit the tissue destruction. AIM: We aimed to evaluate the oxidative stress marker malondialdehyde (MDA) in chronic periodontitis patients following scaling and root planing (SRP) after systemic lycopene supplementation...
January 2017: Journal of Natural Science, Biology, and Medicine
https://www.readbyqxmd.com/read/28250682/evaluation-of-bone-mineral-density-among-type-2-diabetes-mellitus-patients-in-south-karnataka
#9
Athulya G Asokan, Jayakumar Jaganathan, Rajeev Philip, Rino Roopak Soman, Shibu Thomas Sebastian, Fawaz Pullishery
BACKGROUND: Diabetes is one of the world's biggest health problems and the disease affects almost all organ systems. The relationship between type 2 diabetes mellitus (T2DM) and bone mineral density (BMD) has been controversial. Early identification of reduction in bone mass in a diabetic patient may be helpful in preventing the bone loss and future fracture risks. OBJECTIVE: The aim is to study the effect of T2DM on BMD among patients in South Karnataka. MATERIALS AND METHODS: A cross-sectional study was conducted on 150 patients between 40 and 70 years of age which included 75 diabetic and 75 nondiabetic subjects...
January 2017: Journal of Natural Science, Biology, and Medicine
https://www.readbyqxmd.com/read/28250681/dynamic-hip-screw-versus-proximal-femur-locking-compression-plate-in-intertrochanteric-femur-fractures-ao-31a1-and-31a2-a-prospective-randomized-study
#10
Prabhat Agrawal, Sahil Gaba, Saubhik Das, Ranjit Singh, Arvind Kumar, Gajanand Yadav
INTRODUCTION: Intertrochanteric fractures are common in elderly population and pose a significant financial burden to the society. Anatomically contoured proximal femur locking compression plate (PFLCP) is the latest addition in the surgeons' armamentarium to deal with these fractures. It creates an angular stable construct, which will theoretically lessen the risk of failure by screw cut-out and varus collapse, the common mode of DHS failure. We compared DHS with PFLCP in AO type 31A1 and 31A2 intertrochanteric fractures...
January 2017: Journal of Natural Science, Biology, and Medicine
https://www.readbyqxmd.com/read/28250680/vestibular-stimulation-for-management-of-premenstrual-syndrome
#11
Minu Johny, Sai Sailesh Kumar, Archana Rajagopalan, Joseph Kurien Mukkadan
OBJECTIVES: The present study was undertaken to observe the effectiveness of vestibular stimulation in the management of premenstrual syndrome (PMS). MATERIALS AND METHODS: The present study was an experimental study; twenty female participants of age group 18-30 years were recruited in the present study. Conventional swing was used to administer vestibular stimulation. Variables were recorded before and after vestibular stimulation and compared. RESULTS: Depression and stress scores are significantly decreased after 2 months of intervention...
January 2017: Journal of Natural Science, Biology, and Medicine
https://www.readbyqxmd.com/read/28250679/eclectic-mixed-model-method-for-upper-extremity-functional-recovery-in-stroke-rehabilitation-a-pilot-study
#12
K Vijaya Kumar, Abraham M Joshua, Rakshith Kedambadi, P Prasanna Mithra
BACKGROUND: Eclectic treatment method is a flexible approach that uses techniques drawn from various schools of thought involving several treatment methods and allows the therapist to adapt to each client's individual needs. Wider application for eclectic approach is however limited in stroke rehabilitation. AIM: The objective is to find out whether eclectic approach improves upper extremity (UE) functional recovery in acute stroke rehabilitation. METHODOLOGY: Twenty-five postacute unilateral supratentorial stroke subjects recruited from tertiary care hospitals recovered with Stage 2-5 in Brunnstorm stage of UE motor recovery (BRS-UE) underwent 45 min of eclectic approach for UE every day involving seven different treatment methods (5 min for each method) for 6 days consecutively...
January 2017: Journal of Natural Science, Biology, and Medicine
https://www.readbyqxmd.com/read/28250678/spirometry-findings-among-drug-users-in-the-indonesian-national-narcotics-and-illicit-drug-bureau-rehabilitation-center
#13
Erlang Samoedro, Faisal Yunus, Budhi Antariksa, Fariz Nurwidya
BACKGROUND: The increasing prevalence of drug user in Indonesia is affecting the health sectors. The lungs health were affected by the use of the illicit drug. However, lung function among drug users is still unclear. METHODS: This descriptive-analytic study involves 144 drug users who met the inclusion criteria. Chest X-ray was performed to identify the subject with pulmonary tuberculosis to exclude from the study. Subjects were then undergone spirometry test and interviewed using questionnaires...
January 2017: Journal of Natural Science, Biology, and Medicine
https://www.readbyqxmd.com/read/28250677/assessment-of-changes-in-insulin-requirement-in-patients-of-type-2-diabetes-mellitus-on-maintenance-hemodialysis
#14
M J Sudha, Halma S Salam, S Viveka, A L Udupa
BACKGROUND: Hemodialysis improves insulin sensitivity. Currently, there is no recommendation for the adjustment of insulin dose on dialysis day and nondialysis day in diabetic patients. This study was undertaken to determine the variations in insulin requirement based on blood glucose levels on dialysis days and nondialysis days in type 2 diabetic patients with chronic kidney disease on maintenance hemodialysis. METHODOLOGY: Twenty-eight diabetic patients on hemodialysis were recruited into the study after obtaining written informed consent and approval from Azeezia Ethics Committee...
January 2017: Journal of Natural Science, Biology, and Medicine
https://www.readbyqxmd.com/read/28250676/high-rates-of-diabetes-reversal-in-newly-diagnosed-asian-indian-young-adults-with-type-2-diabetes-mellitus-with-intensive-lifestyle-therapy
#15
Vijaya Sarathi, Anish Kolly, H B Chaithanya, C S Dwarakanath
AIMS: There are variable reports on the reversibility of type 2 diabetes mellitus (type 2 DM) with higher rates among younger patients with short duration of diabetes. Hence, we studied the reversibility of diabetes among young adults with newly diagnosed type 2 DM. METHODS: This prospective study included 32 patients with newly diagnosed type 2 DM. All type 2 DM patients were initially treated with intensive lifestyle therapy (ILT) (low-calorie diet [1500 kcal/day] and brisk walking for 1 h/day])...
January 2017: Journal of Natural Science, Biology, and Medicine
https://www.readbyqxmd.com/read/28250675/determination-of-the-frequency-of-the-most-immunogenic-rhesus-antigens-among-saudi-donors-in-king-abdulaziz-medical-city-riyadh
#16
Mohieldin Elsayid, Faris Saeed Al Qahtani, Abdulaziz Mohammed Al Qarni, Faisal Almajed, Faisal Al Saqri, Shoeb Qureshi
BACKGROUND: The Rhesus (Rh) blood group system is one of the most polymorphic and immunogenic systems known in humans, because of its immunogenicity along with ABO grouping, RhD antigen testing was made mandatory before issuing a compatible blood. At present, there are five major antigens, i.e., D, C, E, c, and e in Rh blood group system. AIMS: The aim of this study is to provide essential data about the distribution of the major Rh antigens and the most common phenotype among the Saudi population...
January 2017: Journal of Natural Science, Biology, and Medicine
https://www.readbyqxmd.com/read/28250674/incidence-bacteriology-and-clinical-outcome-of-ventilator-associated-pneumonia-at-tertiary-care-hospital
#17
Harsha V Patil, Virendra C Patil
BACKGROUND: Ventilator-associated pneumonia (VAP) is the most frequent Intensive Care Unit acquired infection. AIMS: The aim is to determine the incidence, bacteriology and factors affecting VAP and to determine the multi-drug resistant (MDR) pathogens. SETTINGS AND DESIGN: This was a prospective observational study conducted over a period of 1 year from April 1, 2011, to March 31, 2012. MATERIALS AND METHODS: The patients fulfilling criteria of VAP were included in this study...
January 2017: Journal of Natural Science, Biology, and Medicine
https://www.readbyqxmd.com/read/28250673/a-study-on-posttraumatic-experience-of-road-traffic-accident-afflicted-maxillofacial-trauma-patient-at-tertiary-hospital
#18
Santosh Kumar Yadav, Suraksha Shrestha
OBJECTIVES: Patients are usually left in a vulnerable state after an accident. Because of this, they long for a good encounter when they are brought to the hospital. Physical impairment and psychological morbidities are some of the complications that can occur to them. Traditionally, surgeons tend to pay little attention to a patient's emotional and psychological perspective. The aim of this study was to understand the experience of oral and maxillofacial trauma patients due to road traffic accident right from immediate after the accident till the end of definitive treatment...
January 2017: Journal of Natural Science, Biology, and Medicine
https://www.readbyqxmd.com/read/28250672/utility-of-cytokine-adhesion-molecule-and-acute-phase-proteins-in-early-diagnosis-of-neonatal-sepsis
#19
M A Fattah, Al Fadhil A Omer, S Asaif, R Manlulu, T Karar, A Ahmed, A Aljada, Ayman M Saleh, Shoeb Qureshi, A Nasr
BACKGROUND AND AIM: Neonatal infection, including bacterial sepsis, is a major health care issue with an annual global mortality in excess of one million lives. Therefore, this study aimed to evaluate the potential diagnostic value of C-reactive protein (CRP), E-selectin, procalcitonin (PCT), interleukins-6 (IL-6), and tumor necrosis factor-α (TNF-α) both independently and in combination for the diagnosis of neonatal sepsis in its earliest stages. MATERIALS AND METHODS: A total of 320 subjects were included in this study...
January 2017: Journal of Natural Science, Biology, and Medicine
https://www.readbyqxmd.com/read/28250671/generic-versus-branded-medicines-an-observational-study-among-patients-with-chronic-diseases-attending-a-public-hospital-outpatient-department
#20
Manisha Das, Supriyo Choudhury, Somnath Maity, Avijit Hazra, Tirthankar Pradhan, Aishee Pal, Ranendra Kumar Roy
BACKGROUND: The concept of generic prescription is widely accepted in various parts of the world. Nevertheless, it has failed to gain popularity in India due to factors such as nonavailability and distrust on the product quality. However, since 2012, the Government of West Bengal, India, has initiated exclusive generic drug outlets called "fair price medicine shop" (FPMS) inside the government hospital premises in a "public-private-partnership" model. This study was undertaken to evaluate the experience and attitude of patients who were consuming generic drugs purchased from these FPMS...
January 2017: Journal of Natural Science, Biology, and Medicine
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