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Allergy & Rhinology

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https://www.readbyqxmd.com/read/29070277/an-ergonomic-assessment-of-operating-table-and-surgical-stool-heights-for-seated-otolaryngology-procedures
#1
Anam F Azimuddin, Erik K Weitzel, Kevin C McMains, Philip G Chen
BACKGROUND: Musculoskeletal injuries, such as neck and back pain, during a surgeon's career are common. However, studies on ergonomics are limited with regard to seated otolaryngologic procedures. Key elements of an ergonomic operating environment include the height of operating tables and surgical chairs. Surgeons benefit from proper support and positioning to prevent musculoskeletal injuries and reduce occupational risk. OBJECTIVE: The purpose of this study was to evaluate operating table and surgical seat heights, and determine whether adjustments can be made for various surgeon physiques...
October 1, 2017: Allergy & Rhinology
https://www.readbyqxmd.com/read/29070276/multiple-doses-of-icatibant-used-during-pregnancy
#2
Lauren W Kaminsky, Theodore Kelbel, Fay Ansary, Timothy Craig
BACKGROUND: Hereditary angioedema (HAE) is a life-long disease that often manifests by puberty. Treatment of attacks is essential to improve quality of life and to decrease morbidity and mortality. During pregnancy, treatment is limited because multiple treatment options, including icatibant, are not approved for use during pregnancy. OBJECTIVE: We report the outcomes of three pregnancies during which icatibant was used by a patient with HAE with normal C1-inhibitor for treatment of attacks...
October 1, 2017: Allergy & Rhinology
https://www.readbyqxmd.com/read/29070275/long-term-follow-up-of-a-patient-with-malignant-transformation-of-inverted-papilloma-into-sinonasal-undifferentiated-carcinoma
#3
Carolyn A Orgain, Terry Y Shibuya, Lester D Thompson, David B Keschner, Rohit Garg, Jivianne T Lee
INTRODUCTION: Inverted papillomas (IP) are benign sinonasal neoplasms, which account for 0.5-4% of all nasal tumors. IPs have been known to transform into squamous cell carcinoma in 5-15% of cases. Rarely, transformations to other malignancies have been reported. Here we report a unique case of malignant transformation of an IP into sinonasal undifferentiated carcinoma (SNUC). METHODS: A case report with a literature review; institutional review board exempted. The clinical presentation, radiographic features, surgical intervention, histopathologic analysis, treatment, and outcome of the case were examined...
October 1, 2017: Allergy & Rhinology
https://www.readbyqxmd.com/read/29070274/long-term-omalizumab-use-in-the-treatment-of-exercise-induced-anaphylaxis
#4
Mark R Peterson, Christopher A Coop
Reported is a case of a 39-year-old male who was diagnosed with exercise-induced anaphylaxis (EIA). He was initially treated prophylactically with fexofenadine, montelukast, and ranitidine. He also used an epinephrine autoinjector as needed. He was refractory to these medications and continued to have episodes of EIA. He was then started on a trial of omalizumab, an immunoglobulin E monoclonal antibody, and had resolution of the EIA episodes. After discontinuation of the omalizumab, the EIA episodes returned...
October 1, 2017: Allergy & Rhinology
https://www.readbyqxmd.com/read/29070273/oral-immunotherapy-in-children-with-ige-mediated-hen-s-egg-allergy-follow-ups-at-2-5-and-7-years
#5
Paolo Meglio, Paolo Gianni Giampietro, Rossella Carello, Elena Galli
BACKGROUND: The present report was a follow-up investigation at 2.5- and 7-year intervals of a previous study of 20 children with moderate-to-severe immunoglobulin E (IgE) mediated hen's egg (HE) allergy who received oral immunotherapy (OIT) with raw HE. The study design of the previous study divided the 20 subjects into two groups of 10 each: (1) group 1, the OIT group (OIT-G), and, (2) group 2, an age-matched control group (C-G). In that study, 8 of 10 of the children in the OIT-G were successfully desensitized, one child was partially desensitized, and desensitization failed in one child...
October 1, 2017: Allergy & Rhinology
https://www.readbyqxmd.com/read/29070272/a-multicenter-prospective-noninterventional-study-in-a-norwegian-cohort-of-patients-with-moderate-to-severe-allergic-rhinitis-treated-with-mp-azeflu
#6
Ralph Dollner, Petter Lorentz Larsen, Sinan Dheyauldeen, Sverre Steinsvåg
BACKGROUND: Allergic Rhinitis and its Impact on Asthma guidelines recently recommended a treatment strategy for allergic rhinitis (AR) based on disease control rather than symptom severity by using a visual analog scale (VAS) to categorize control. OBJECTIVES: To evaluate the effectiveness of MP-AzeFlu (Dymista®) by using this VAS in routine clinical practice in Norway. MP-AzeFlu comprises a novel formulation that contains azelastine hydrochloride, fluticasone propionate and excipients delivered in a single spray...
October 1, 2017: Allergy & Rhinology
https://www.readbyqxmd.com/read/29070271/characterization-of-t-cell-subpopulations-in-patients-with-chronic-rhinosinusitis-with-nasal-polyposis
#7
Pascal Ickrath, Norbert Kleinsasser, Xin Ding, Christian Ginzkey, Niklas Beyersdorf, Rudolf Hagen, Thomas Kerkau, Stephan Hackenberg
BACKGROUND: There is an ongoing discussion concerning the potential origins of chronic rhinosinusitis with nasal polyposis (CRSwNP). OBJECTIVE: The aim of this study was to quantify subpopulations of T cells in peripheral blood and nasal polyps in CRSwNP to examine their influence on the etiology of this disease. METHODS: Tissue and blood samples were collected from 11 patients who underwent nasal sinus surgery, and these samples were analyzed by multicolor flow cytometry...
October 1, 2017: Allergy & Rhinology
https://www.readbyqxmd.com/read/29070270/prenatal-maternal-depression-related-to-allergic-rhinoconjunctivitis-in-the-first-5-years-of-life-in-children-of-the-eden-mother-child-cohort-study
#8
Cailiang Zhou, Gladys Ibanez, Vincent Miramont, Magali Steinecker, Nour Baiz, Soutrik Banerjee, Jocelyne Just, Isabella Annesi-Maesano, Julie Chastang
Backgroud: Evidence about the relationship between prenatal maternal depression and the development of childhood asthma and allergies in early life is scarce. We aimed to examine this relationship by using data set of EDEN mother-child cohort study. A total of 1139 children were followed-up until the age of 5 years. METHODS: Prenatal maternal depression was self-reported by using the Centre for Epidemiological Studies-Depression scale (CES-D) questionnaire and was classified into binary variable (maternal depression [CES-D score of ≥16] and no maternal depression [CES-D score of <16])...
October 1, 2017: Allergy & Rhinology
https://www.readbyqxmd.com/read/29070269/the-study-of-a-possible-correlation-between-serum-levels-of-interleukin-17-and-clinical-severity-in-patients-with-allergic-rhinitis
#9
Mai Aly Gharib Aly, Mohamed Tawfik El Tabbakh, Waheed Fawzy Heissam, Said Hamed Abbadi
INTRODUCTION: Allergic rhinitis (AR) is one of the most common allergic diseases, which affects ∼20% of the world's population. T-helper (Th) type 2 cells produce interleukin (IL) 4 and IL-13, and mediate allergic responses, and these cytokines have been extensively studied as key players in the atopic airway diseases. However, the involvement of Th17 cells and IL-17 in AR has not been clearly examined. AIM: To reevaluate AR clinical severity with serum IL-17, whether IL-17 affects the disease alone or in contribution with the atopic predisposition...
October 1, 2017: Allergy & Rhinology
https://www.readbyqxmd.com/read/29070268/evaluation-of-a-new-and-simple-classification-for-endoscopic-sinus-surgery
#10
Kengo Kanai, Mitsuhiro Okano, Takenori Haruna, Takaya Higaki, Ryotaro Omichi, Sei-Ichiro Makihara, Munechika Tsumura, Shin Kariya, Yuji Hirata, Kazunori Nishizaki
OBJECTIVE: In 2013, the Japanese Rhinologic Society proposed a simple classification for endoscopic sinus surgery (ESS). This classification consists of five procedures (type I, fenestration of the ostiomeatal complex, with uncinectomy and widening of the natural ostium; type II, single-sinus procedure, with manipulating the inside of the sinus; type III, polysinus procedure; type IV, pansinus procedure; type V, extended procedure beyond the sinus wall). The clinical relevance of this classification in chronic rhinosinusitis (CRS) and paranasal sinus cyst was evaluated...
October 1, 2017: Allergy & Rhinology
https://www.readbyqxmd.com/read/29070267/barosinusitis-comprehensive-review-and-proposed-new-classification-system
#11
Reza Vaezeafshar, Alkis J Psaltis, Vidya K Rao, David Zarabanda, Zara M Patel, Jayakar V Nayak
BACKGROUND: Barosinusitis, or sinus barotrauma, may arise from changes in ambient pressure that are not compensated by force equalization mechanisms within the paranasal sinuses. Barosinusitis is most commonly seen with barometric changes during flight or diving. Understanding and better classifying the pathophysiology, clinical presentation, and management of barosinusitis are essential to improve patient care. OBJECTIVES: To perform a comprehensive review of the available literature regarding sinus barotrauma...
October 1, 2017: Allergy & Rhinology
https://www.readbyqxmd.com/read/28583236/complete-response-of-skull-base-inverted-papilloma-to-chemotherapy-case-report
#12
Edward C Kuan, John W Frederick, Miguel F Palma Diaz, Dean W Lim, Jeffrey D Suh
BACKGROUND: Inverted papilloma (IP) is the most common benign sinonasal neoplasm. Endoscopic techniques, improved understanding of pathophysiology, and novel surgical approaches have allowed rhinologists to treat IPs more effectively, with surgery being the mainstay of therapy. Frontal sinus IP poses a challenge for surgical therapy due to complex anatomy and potentially difficult surgical access. OBJECTIVES: We reported a unique case of a massive frontal sinus IP that presented with intracranial and orbital extension, with near resolution after chemotherapy...
June 1, 2017: Allergy & Rhinology
https://www.readbyqxmd.com/read/28583235/type-1-kounis-syndrome-in-a-patient-with-idiopathic-anaphylaxis
#13
Monica Sandhu, Jason Casselman, Brian Peppers, Haig Tcheurekdjian, Robert W Hostoffer
Anaphylactic insults that cause cardiovascular signs and symptoms have been defined as Kounis syndrome, which has been associated with specific triggered anaphylactic reactions. Kounis syndrome has not been described in patients with no evidence of coronary artery disease (type I Kounis) in a scenario of idiopathic anaphylaxis. We reported a case of a 65-year-old white woman with no evidence of coronary artery disease who experienced two myocardial infarctions on separate occasions attributable to idiopathic anaphylaxis...
June 1, 2017: Allergy & Rhinology
https://www.readbyqxmd.com/read/28583234/bilateral-silent-sinus-syndrome-a-rare-case-and-review-of-literature
#14
Michal Trope, Joseph S Schwartz, Bobby A Tajudeen, David W Kennedy
OBJECTIVE: In this report, we presented a rare case of bilateral silent sinus syndrome (SSS) in an otherwise healthy 57-year-old man treated with functional endoscopic sinus surgery (FESS). A systematic review of the literature regarding bilateral SSS was performed. CASE REPORT: A 57-year-old man with well-controlled allergic rhinitis in the absence of previous surgery or trauma presented with bilateral SSS, which was successfully managed with bilateral FESS. METHODS: A medical literature data base search of the terms "silent sinus syndrome" "maxillary atelectasis," "imploding antrum syndrome," and "bilateral silent sinus syndrome" was performed...
June 1, 2017: Allergy & Rhinology
https://www.readbyqxmd.com/read/28583233/myxofibrosarcoma-of-the-maxillary-sinus
#15
Anni Wong, Richard Chan Woo Park, Neena M Mirani, Jean Anderson Eloy
BACKGROUND: Myxofibrosarcoma (MFS) is a common sarcoma in the extremities of older individuals but is extremely uncommon in the head and neck region. Diagnosis may be challenging but is critical to the management of the patient. We discuss the radiographic and histopathologic characteristics of this destructive tumor. The distinguishing features of MFS and its differential diagnosis are reviewed to familiarize the managing otolaryngologist with this rare entity. METHODS: A 61-year-old woman presents with a 6-week history of severe left facial pain and left eye pain...
June 1, 2017: Allergy & Rhinology
https://www.readbyqxmd.com/read/28583232/effect-of-topical-beclomethasone-on-inflammatory-markers-in-adults-with-eosinophilic-esophagitis-a-pilot-study
#16
Neeti Bhardwaj, Faoud Ishmael, Erik Lehman, Deborah Bethards, Francesca Ruggiero, Gisoo Ghaffari
BACKGROUND: Topical corticosteroids have proven efficacy in the treatment of eosinophilic esophagitis (EoE) and are considered the cornerstone of therapy. OBJECTIVE: To evaluate the effect of topical beclomethasone dipropionate (BDP) therapy on clinical outcomes, esophageal eosinophilia, and other markers of inflammation in patients with EoE. METHODS: Nine subjects with a biopsy-proven diagnosis of EoE were enrolled. In a cross-over design, the subjects were randomly assigned to a sequence of BDP and placebo...
June 1, 2017: Allergy & Rhinology
https://www.readbyqxmd.com/read/28583231/utility-of-intraoperative-flexible-endoscopy-in-frontal-sinus-surgery
#17
Eric T Carniol, Alejandro Vázquez, Tapan D Patel, James K Liu, Jean Anderson Eloy
BACKGROUND: Surgical management of the frontal sinus can be challenging. Extensive frontal sinus pneumatization may form a far lateral or supraorbital recess that can be difficult to reach by conventional endoscopic surgical techniques, requiring extended approaches such as the Draf III (or endoscopic modified Lothrop) procedure. Rigid endoscopes may not allow visualization of these lateral limits to ensure full evacuation of the disease process. METHODS: Here we describe the utility of intraoperative flexible endoscopy in two patients with far lateral frontal sinus disease...
June 1, 2017: Allergy & Rhinology
https://www.readbyqxmd.com/read/28583230/differential-expression-of-micrornas-and-their-possible-roles-in-patients-with-chronic-idiopathic-urticaria-and-active-hives
#18
Ching-Kow E Lin, John S Kaptein, Javed Sheikh
BACKGROUND: Chronic idiopathic urticaria (CIU) is a complicated skin disease with unknown pathophysiology. MicroRNAs (miRNA) have been shown to be active in cellular regulation. The goal of this pilot study was to examine whether miRNAs may be involved in the regulation of CIU or as biomarkers for CIU. METHODS: Four groups of three patients each were selected: patients with either active hives or no hives and with positive or negative chronic urticaria (CU) index results...
June 1, 2017: Allergy & Rhinology
https://www.readbyqxmd.com/read/28583229/landmarks-for-rapid-localization-of-the-sphenopalatine-foramen-a-radiographic-morphometric-analysis
#19
Anne K Maxwell, Henry P Barham, Anne E Getz, Todd T Kingdom, Vijay R Ramakrishnan
BACKGROUND: Transnasal endoscopic sphenopalatine artery ligation is becoming the procedure of choice for surgical management of intractable posterior epistaxis. Landmarks for localization of the sphenopalatine foramen can assist in rapid surgical exposure of the sphenopalatine artery. OBJECTIVE: This study examined distances from easily identified endoscopic surgical landmarks to the sphenopalatine foramen. METHODS: By using computed tomography of the sinus to study radiologic anatomy in 50 adults, distances were measured between five simple endoscopic landmarks and the sphenopalatine foramen...
June 1, 2017: Allergy & Rhinology
https://www.readbyqxmd.com/read/28583228/diagnosing-environmental-allergies-comparison-of-skin-prick-intradermal-and-serum-specific-immunoglobulin-e-testing
#20
Denisa Ferastraoaru, Maria Shtessel, Elizabeth Lobell, Golda Hudes, David Rosenstreich, Gabriele de Vos
BACKGROUND: Allergists commonly perform intradermal skin testing (IDST) after negative skin-prick testing (SPT) to comprehensively diagnose environmental allergic sensitization. However, with the availability of modern methods to detect serum-specific immunoglobulin E (ssIgE), it is unclear if ssIgE testing could substitute for IDST. OBJECTIVE: To determine the efficacy of ssIgE testing and IDST when added to SPT in diagnosing environmental allergic sensitizations...
June 1, 2017: Allergy & Rhinology
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