journal
MENU ▼
Read by QxMD icon Read
search

Brain and Behavior

journal
https://www.readbyqxmd.com/read/29777579/acute-blood-pressure-levels-and-long-term-outcome-in-ischemic-stroke
#1
Johan-Emil Bager, Clara Hjalmarsson, Karin Manhem, Bjorn Andersson
OBJECTIVES: Elevated blood pressure (BP) is common in acute ischemic stroke, but its effect on outcome is not fully understood. We aimed to investigate the association of baseline BP and BP change within the first day after stroke with stroke severity, functional outcome, and mortality. METHODS: Patients admitted to hospital with acute ischemic stroke (IS) from 15 February 2005 through 31 May 2009 were consecutively included. Acute stroke severity and functional outcome at three and twelve months were investigated using multivariate regression analysis; the association between BP and all-cause mortality at one, three, and twelve was investigated by Cox proportional hazard regression and Kaplan-Meier survival curves...
May 18, 2018: Brain and Behavior
https://www.readbyqxmd.com/read/29770601/prehospital-identification-of-factors-associated-with-death-during-one-year-follow-up-after-acute-stroke
#2
Per-Olof Hansson, Magnus Andersson Hagiwara, Peter Brink, Johan Herlitz, Birgitta Wireklint Sundström
OBJECTIVES: In acute stroke, the risk of death and neurological sequelae are obvious threats. The aim of the study was to evaluate the association between various clinical factors identified by the emergency medical service (EMS) system before arriving at hospital and the risk of death during the subsequent year among patients with a confirmed stroke. MATERIAL AND METHODS: All patients with a diagnosis of stroke as the primary diagnosis admitted to a hospital in western Sweden (1...
May 16, 2018: Brain and Behavior
https://www.readbyqxmd.com/read/29749715/altered-resting-state-hippocampal-and-caudate-functional-networks-in-patients-with-obstructive-sleep-apnea
#3
Xiaopeng Song, Bhaswati Roy, Daniel W Kang, Ravi S Aysola, Paul M Macey, Mary A Woo, Frisca L Yan-Go, Ronald M Harper, Rajesh Kumar
INTRODUCTION: Brain structural injury and metabolic deficits in the hippocampus and caudate nuclei may contribute to cognitive and emotional deficits found in obstructive sleep apnea (OSA) patients. If such contributions exist, resting-state interactions of these subcortical sites with cortical areas mediating affective symptoms and cognition should be disturbed. Our aim was to examine resting-state functional connectivity (FC) of the hippocampus and caudate to other brain areas in OSA relative to control subjects, and to relate these changes to mood and neuropsychological scores...
May 10, 2018: Brain and Behavior
https://www.readbyqxmd.com/read/29745050/aquaporin-4-knockout-mice-exhibit-increased-hypnotic-susceptibility-to-ketamine
#4
Yunluo Lv, Wangshu Dai, Ai Ge, Yi Fan, Gang Hu, Yinming Zeng
PURPOSE: This study examines anesthetic/hypnotic effects of ketamine in AQP4 knockout (KO) and wild-type (WT) mice with the particular focus on neurotransmission. MATERIALS AND METHODS: Ketamine (100 mg/kg) was intraperitoneally injected in 16 WT and 16 KO mice. The hypnotic potencies were evaluated by the loss of the righting reflex (LORR). The amino acids neurotransmitter levels in prefrontal cortex were measured by microdialysis. RESULTS: This study demonstrated that AQP4 knockout significantly shortened the latency compared with WT mice (98...
May 9, 2018: Brain and Behavior
https://www.readbyqxmd.com/read/29741225/prediction-of-vascular-abnormalities-on-ct-angiography-in-patients-with-acute-headache
#5
Imanda M E Alons, Ben F J Goudsmit, Korné Jellema, Marianne A A van Walderveen, Marieke J H Wermer, Ale Algra
OBJECTIVES: Patients with acute headache increasingly undergo CT-angiography (CTA) to evaluate underlying vascular causes. The aim of this study is to determine clinical and non-contrast CT (NCCT) criteria to select patients who might benefit from CTA. METHODS: We retrospectively included patients with acute headache who presented to the emergency department of an academic medical center and large regional teaching hospital and underwent NCCT and CTA. We identified factors that increased the probability of finding a vascular abnormality on CTA, performed multivariable regression analyses and determined discrimination with the c-statistic...
May 9, 2018: Brain and Behavior
https://www.readbyqxmd.com/read/29740975/similarities-between-the-responses-to-ant-dbs-and-prior-vns-in-refractory-epilepsy
#6
Toni Kulju, Joonas Haapasalo, Kai Lehtimäki, Sirpa Rainesalo, Jukka Peltola
OBJECTIVES: Neurostimulation has offered new treatment options in refractory epilepsy, first with vagus nerve stimulation (VNS) and more recently with deep brain stimulation (DBS). There is a lack of previous detailed data assessing the relationship between VNS and ANT-DBS. The aim of this study was to investigate the potential correlation between therapeutic responses to VNS and ANT-DBS. MATERIALS AND METHODS: A total of 11 patients with previous VNS therapy underwent ANT-DBS implantation...
May 8, 2018: Brain and Behavior
https://www.readbyqxmd.com/read/29733529/sensor-based-gait-analysis-in-atypical-parkinsonian-disorders
#7
Cecilia Raccagni, Heiko Gaßner, Sabine Eschlboeck, Sylvia Boesch, Florian Krismer, Klaus Seppi, Werner Poewe, Bjoern M Eskofier, Juergen Winkler, Gregor Wenning, Jochen Klucken
BACKGROUND AND OBJECTIVES: Gait impairment and reduced mobility are typical features of idiopathic Parkinson's disease (iPD) and atypical parkinsonian disorders (APD). Quantitative gait assessment may have value in the diagnostic workup of parkinsonian patients and as endpoint in clinical trials. The study aimed to identify quantitative gait parameter differences in iPD and APD patients using sensor-based gait analysis and to correlate gait parameters with clinical rating scales. SUBJECTS AND METHODS: Patients with iPD and APD including Parkinson variant multiple system atrophy and progressive supranuclear palsy matched for age, gender, and Hoehn and Yahr (≤3) were recruited at two Movement Disorder Units and assessed using standardized clinical rating scales (MDS-UPDRS-3, UMSARS, PSP-RS)...
May 7, 2018: Brain and Behavior
https://www.readbyqxmd.com/read/29733522/ceruloplasmin-in-parkinson-s-disease-and-the-nonmotor-symptoms
#8
Xuemei Zhao, Ziqiang Shao, Yu Zhang, Fang Liu, Zhibo Liu, Zunjing Liu
OBJECTIVES: To investigate the relationship between ceruloplasmin (CP) and Parkinson's disease (PD), and the correlation between CP level and the time difference between nonmotor symptoms and motor symptoms and the diagnosis were also mentioned. MATERIALS AND METHODS: Sixty-six patients diagnosed with PD for the first time were included in the study. They were divided into CP reduction group (31 cases) and CP normal group (35 cases) according to their CP level. The estimated time difference between nonmotor symptoms and motor symptoms and the diagnosis were recorded respectively...
May 7, 2018: Brain and Behavior
https://www.readbyqxmd.com/read/29729087/liver-injury-after-pulsed-methylprednisolone-therapy-in-multiple-sclerosis-patients
#9
Viviana Nociti, Marco Biolato, Chiara De Fino, Assunta Bianco, Francesco Antonio Losavio, Matteo Lucchini, Giuseppe Marrone, Antonio Grieco, Massimiliano Mirabella
OBJECTIVES: High-dose pulsed methylprednisolone-related liver injury cases have been reported in the literature, but a prospective study in patients with multiple sclerosis (MS) has never been performed. The aim of this study was to evaluate the prevalence and severity of liver injury in patients with MS after pulsed methylprednisolone therapy. METHODS: We performed a prospective observational single-center study on patients with MS treated with i.v. methylprednisolone 1,000 mg/day for 5 days...
May 4, 2018: Brain and Behavior
https://www.readbyqxmd.com/read/29761025/the-dissociations-of-visual-processing-of-hole-and-no-hole-stimuli-an-functional-magnetic-resonance-imaging-study
#10
Qianli Meng, Yan Huang, Ding Cui, Lixia He, Lin Chen, Yuanye Ma, Xudong Zhao
Introduction: "Where to begin" is a fundamental question of vision. A "Global-first" topological approach proposed that the first step in object representation was to extract topological properties, especially whether the object had a hole or not. Numerous psychophysical studies found that the hole (closure) could be rapidly recognized by visual system as a primitive property. However, neuroimaging studies showed that the temporal lobe (IT), which lied at a late stage of ventral pathway, was involved as a dedicated region...
May 2018: Brain and Behavior
https://www.readbyqxmd.com/read/29761024/relationships-between-activity-and-well-being-in-people-with-parkinson-s-disease
#11
Felicitas Ehlen, Katharina Schindlbeck, Lisa Nobis, André Maier, Fabian Klostermann
Objectives: The complex symptomatology of Parkinson' disease (PD) usually goes along with reduced physical activity. Previous studies have indicated positive effects of activating therapies on patients' well-being. This study, therefore, examined how activity in daily life is related to patients' subjective condition. Materials and Methods: Twenty-one PD patients rated their condition every two hours during two routine days and documented the duration and type of their activities (based on the PRISCUS-Physical Activity Questionnaire) during the respective time intervals...
May 2018: Brain and Behavior
https://www.readbyqxmd.com/read/29761023/comparing-outcome-and-recanalization-results-in-patients-with-anterior-circulation-stroke-following-endovascular-treatment-with-and-without-a-treatment-with-rt-pa-a-single-center-study
#12
Mohamed Al-Khaled, Toralf Brüning, Carina Gottwald, Florian Roessler, Georg Royl, Thomas Eckey
Objectives: Endovascular treatment (ET), in addition to a therapy with intravenous recombinant tissue plasminogen activator IV rt-PA in patients with acute ischemic stroke, has been found to improve outcome. However, data about ET in patients who have not received therapy with rt-PA due to contraindications for IV rt-PA are sparse. Comparison of ET with IV rt-PA versus ET alone in patients with stroke is done using a proximal intracranial arterial occlusion (internal carotid artery, middle cerebral artery (M1-Segment))...
May 2018: Brain and Behavior
https://www.readbyqxmd.com/read/29761022/ketogenic-diet-effects-on-52-children-with-pharmacoresistant-epileptic-encephalopathy-a-clinical-prospective-study
#13
Qiong Wu, Hua Wang, Yu Ying Fan, Jun Mei Zhang, Xue Yan Liu, Xiu Ying Fang, Feng Hua Yang, Qing Jun Cao, Ying Qi
Objective: To evaluate the clinical impact of ketogenic diet (KD) on children with pharmacoresistant epileptic encephalopathy. Methods: In all, 52 children with pharmacoresistant epileptic encephalopathy that diagnosed in our hospital from July 2012 to June 2015 were selected, including West syndrome 38 cases, Lennox-Gastaut Syndrome 7 cases, Doose Syndrome 1 case, and Dravet syndrome 6 cases, and the effect, compliance, adverse reactions, electroencephalogram (EEG), and cognitive function were analyzed...
May 2018: Brain and Behavior
https://www.readbyqxmd.com/read/29761021/human-inpc-therapy-leads-to-improvement-in-functional-neurologic-outcomes-in-a-pig-ischemic-stroke-model
#14
Vivian W Lau, Simon R Platt, Harrison E Grace, Emily W Baker, Franklin D West
Introduction: Stroke is the leading cause of disability in the United States but current therapies are limited with no regenerative potential. Previous translational failures have highlighted the need for large animal models of ischemic stroke and for improved assessments of functional outcomes. The aims of this study were first, to create a post-stroke functional outcome assessment scale in a porcine model of middle cerebral artery occlusion (MCAO) and second, to use this scale to determine the effect of human-induced-pluripotent-cell-derived neural progenitor cells (iNPCs) on functional outcome in this large animal stroke model...
May 2018: Brain and Behavior
https://www.readbyqxmd.com/read/29761020/tested-and-reported-executive-problems-in-children-and-youth-epilepsy
#15
Erik Hessen, Kristin Å Alfstad, Halvor Torgersen, Morten I Lossius
Objectives: Executive problems in children and youth with epilepsy influence their ability to handle important aspects of daily life activities. The present study sought to explore factors associated with executive problems for patients with epilepsy in this age group. Methods: The cohort consisted of 97 consecutive patients at the National Centre for Epilepsy in Norway, aged 10-19 years, with focal or genetic generalized epilepsy. All underwent tests of executive functions (D-KEFS), the Behavior Rating Inventory for Executive Function (BRIEF), and screening for psychiatric symptoms, using the Strengths and Difficulties Questionnaire (SDQ)...
May 2018: Brain and Behavior
https://www.readbyqxmd.com/read/29761019/assessment-of-sleep-quality-using-cardiopulmonary-coupling-analysis-in-patients-with-parkinson-s-disease
#16
Lindi Chen, Chunyan Liu, Zhinan Ye, Binda Wang, Songbin He
Objectives: To assess the sleep quality of patients with Parkinson's disease (PD) and evaluate the effect of cardiopulmonary coupling (CPC) analysis on sleep quality and its correlation with subjective complaints in patients with PD. Methods: Our study included 42 patients with PD and 30 healthy controls. CPC analysis and the Pittsburgh Sleep Quality Index (PSQI) were used to evaluate the sleep quality of subjects. Results: High-frequency coupling (HFC) and sleep efficiency were significantly lower in the PD than in the control group, whereas very low-frequency coupling (VLFC) and sleep latency were significantly higher in the PD than in the control group...
May 2018: Brain and Behavior
https://www.readbyqxmd.com/read/29761018/behavioral-and-neurophysiological-abnormalities-during-cued-continuous-performance-tasks-in-patients-with-mild-traumatic-brain-injury
#17
Weixiang Zhao, Ruhong Wu, Suhong Wang, Haihui Qi, Yitao Qian, Suinuan Wang
Objective: This study's aim was to investigate the features and neural mechanisms of sustained attention in patients with mild traumatic brain injury (mTBI) by comparing and analyzing neuropsychological, behavioral, event-related potentials, and event-related desynchronization and synchronization between mTBI patients and healthy controls. Methods: Twenty mTBI patients with mTBI and 20 healthy controls underwent the Mini-Mental State Examination (MMSE) and a cued continuous performance task (AX-CPT)...
May 2018: Brain and Behavior
https://www.readbyqxmd.com/read/29761017/eleven-years-experience-with-intrathecal-baclofen-complications-risk-factors
#18
Elke Pucks-Faes, Gabriel Hitzenberger, Heinrich Matzak, Elena Fava, Giulio Verrienti, Ilse Laimer, Josef Fritz, Leopold Saltuari
Objective: Treatment with intrathecal baclofen (ITB) is commonly used in patients with severe spasticity. However, complications may occur after implantation of the ITB-device, albeit mainly procedure- and device-related problems. The aim of the study was to assess surgical- as well as catheter- and pump-related complications and define their risk factors. Methods: We retrospectively evaluated all patients with an implanted ITB-device who were treated at the Department of Neurology, Hochzirl Hospital, Zirl, Austria, between 2006 and 2016...
May 2018: Brain and Behavior
https://www.readbyqxmd.com/read/29761016/the-effects-of-cognitive-behavioral-therapy-on-resting-state-functional-brain-network-in-drug-naive-patients-with-obsessive-compulsive-disorder
#19
Ping Li, Xiangyun Yang, Andrew J Greenshaw, Sufang Li, Jia Luo, Haiying Han, Jing Liu, Zhaoxi Zhong, Zhihua Guo, Hongfang Xiong, Shumin Yao, Yunhui Chen, Jing Sun, Zhanjiang Li
Objectives: Although cognitive behavioral therapy (CBT) is an effective treatment for obsessive-compulsive disorder (OCD), the treatment mechanisms remain poorly understood. This study aimed to investigate the effects of CBT on changes in the intrinsic whole-brain functional network of OCD patients. Materials and Methods: Twenty drug-naive and noncomorbid OCD patients were recruited, and resting-state functional magnetic resonance imaging was performed before and after 12 weeks of CBT...
May 2018: Brain and Behavior
https://www.readbyqxmd.com/read/29761015/the-influence-of-thc-cbd-oromucosal-spray-on-driving-ability-in-patients-with-multiple-sclerosis-related-spasticity
#20
Elisabeth G Celius, Carlos Vila
Background: Driving ability is a key function for the majority of patients with multiple sclerosis (MS) to help maintain daily interactions. Both physical and cognitive disability, as well as treatments, may affect the ability to drive. Spasticity is a common symptom associated with MS, and it may affect driving performance either directly or via the medications used to treat it. In this article, we review the evidence relating the antispasticity medicine, Δ9 -tetrahydrocannabinol:cannabidiol (THC:CBD) oromucosal spray (Sativex® ), and its potential impact on driving performance...
May 2018: Brain and Behavior
journal
journal
43782
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"