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Environmental Health and Toxicology

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https://www.readbyqxmd.com/read/28183164/estrogenic-activity-of-zinc-pyrithione-an-in-vivo-and-in-vitro-study
#1
Seung Jun Kwack, Kyung Sik Yoon, Nam Hee Youn, Hyun Gyung Gu
Objectives: Zinc pyrithione is commonly used to prevent dandruff and seborrheic dermatitis. Many consumers are exposed daily to high doses of zinc pyrithione, causing serious concerns about its toxicity. The reproductive and developmental toxicities were previously reported in pregnant rats. However, the estrogenic activity of zinc pyrithione at varying degrees of exposure has been rarely studied. Thus, we performed an uterotrophic assay, E-screen assay, and gene expression profiling to assess the estrogenic activity of zinc pyrithione...
February 9, 2017: Environmental Health and Toxicology
https://www.readbyqxmd.com/read/28111420/a-follow-up-study-of-the-association-between-mobile-phone-use-and-symptoms-of-ill-health
#2
Yong Min Cho, Hee Jin Lim, Hoon Jang, Kyunghee Kim, Jae Wook Choi, Chol Shin, Seung Ku Lee, Jong Hwa Kwon, Nam Kim
Objectives: The duration and frequency of mobile phone calls, and their relationship with various health effects, have been investigated in our previous cross-sectional study. This two-year period follow-up study after aimed to assess the changes in these variables of same subjects. Methods: The study population comprised 532 non-patient adult subjects sampled from the Korean Genome Epidemiology Study. The subjects underwent a medical examination at a hospital in 2012/2013 and revisited the same hospital in 2014/2015 to have the same examination for the characteristics of mobile phone use performed...
December 29, 2016: Environmental Health and Toxicology
https://www.readbyqxmd.com/read/28111419/chemical-colitis-caused-by-hydrogen-peroxide-enema-in-a-child
#3
Jung Kyung Yoo, Joon Sang Lee
A 2-year-old girl, previously healthy, was brought to the Emergency Department because of cramping abdominal pain, recurrent hematochezia after an accidental hydrogen peroxide enema (35%, 5mL) by her caregiver. She was hospitalized to the pediatric department and treated with NPO, intravenous fluid and parenteral antibiotic therapy. Laboratory, radiologic, endoscopic evaluation were performed during admission period. She was discharged with fully recovered state on 10th hospital day, and this may be the first case report of acute chemical colitis by accidental hydrogen peroxide enema in children...
December 29, 2016: Environmental Health and Toxicology
https://www.readbyqxmd.com/read/28111421/combined-approaches-using-aops-and-big-data-to-find-potential-diseases-associated-with-humidifier-disinfectant
#4
Jong-Han Leem, Kyu Hyuck Chung
According to previous survey, about 2 million of people were expected to suffer from toxic effects due to humidifier disinfectant, regardless of healing or not. Extremely small group are recognized as humidifier disinfectants??victims. Up to now, previous research tried to focus on interstitial fibrosis on terminal bronchiole because it is specific finding, compared with other diseases. To figure out overall effects from humidifier disinfectants, we recommend adverse outcome pathways (AOPs) as new approach...
December 23, 2016: Environmental Health and Toxicology
https://www.readbyqxmd.com/read/28111422/humidifier-disinfectant-disaster-what-do-we-know-and-what-are-left-to-be-clarified
#5
Sungkyoon Kim, Domyung Paek
After the initial investigations of Korean CDC in 2011, more than 1,000 suspicious cases of humidifier disinfectant victims were subsequently reported up to 2015, and numbers are still increasing dramatically in 2016 in the midst of prosecutor's office investigation. In this study, we tried to summarize the current understandings of humidifier disinfectant related health effects based upon systemic review of published epidemiologic studies and toxicology investigations. Published studies of humidifier disinfectants were searched through 'pubmed' and 'toxline'?under the heading of 'humidifier disinfectant', and related reports were identified from the references and published report list of regulatory agencies including Korean National Institute of Environmental Research, US Environmental Protection Agency, and EU European Chemicals Agency...
December 4, 2016: Environmental Health and Toxicology
https://www.readbyqxmd.com/read/27608716/humidifier-disinfectant-lung-injury-how-do-we-approach-the-issues
#6
Jihyun Emma Choi PhD, Sang-Bum Hong Md PhD, Kyung-Hyun Do Md PhD, Hwa Jung Kim Md PhD, Seockhoon Chung Md PhD, Eun Lee Md PhD, Jihyun Choi, Soo-Jong Hong
A large portion of the Korean population has been exposed to toxic humidifier disinfectants, and considering that the majority of the victims are infants, the magnitude of the damage is expected to be considerably larger than what has currently been revealed. The current victims are voicing problems caused by various diseases, including but not limited to lung, upper respiratory tract, cardiovascular, kidney, musculoskeletal, eye, and skin diseases, etc. However, there has been difficulty in gaining validation for these health problems and identifying causal relationships due to lack of evidence proving that toxic humidifier disinfectant is the specific causes of extrapulmonary diseases such as allergic rhinitis...
August 29, 2016: Environmental Health and Toxicology
https://www.readbyqxmd.com/read/27608718/relationship-between-residential-district-and-health-related-quality-of-life-in-chungnam-industrial-complex-area
#7
Hee Chan Kim, Sangchul Roh
Objectives: This study aimed to evaluate the relationship between residential district of people, such as power plant, steel-mill and petrochemical industries, and health-related quality of life. Methods: Using a cross-sectional study design, we randomly recruited paticipants for our study from industrial areas(thermoelectric power plant, steel-mill, petrochemical industry) and rural areas. Logistic regression analysis was used to identify the relationships between EQ-5D scores and living region, while controlling for sociodemographic characteristics...
August 26, 2016: Environmental Health and Toxicology
https://www.readbyqxmd.com/read/27608717/a-study-of-risk-factors-associated-with-depression-and-suicidal-ideation-in-a-rural-population
#8
Yosub Joo, Sangchul Roh
Objectives: This study aimed to evaluate the risk factors associated with depression and suicidal ideation in a rural population. Methods: A survey was conducted with 543 farmers from Chungcheongnam province using the Center for Epidemiologic Studies Depression Scale (CES-D) for depression, Lubben Social Network Scale (LSNS) for social support, Swedish Q16 for neurotoxicity symptoms and Park, Kim, and Chon's survey tool for farmer's syndrome. Results: After adjusting for socioeconomic factors using logistic regression analysis, poor self-rated health, low social support and neurotoxicity were positively associated with the risk of depression (OR=9...
August 26, 2016: Environmental Health and Toxicology
https://www.readbyqxmd.com/read/27503469/decreased-absorption-of-midazolam-in-the-stomach-due-to-low-ph-induced-by-co-administration-of-banha-sasim-tang
#9
Jun Hyeon Jo, Sun Joo Kim, Woong-Shik Nam, Eunji Sung, Sangkyu Lee
Objectives: Banha-sasim-tang (BST), which consists of seven different herbs, is one of the most popular herbal formulae for treating gastrointestinal disorders in Eastern Asia. The commonly used herbal medicine is often co-administered with other therapeutic drugs, which raises the possibility of herb-drug interactions and may modify the clinical safety profile of therapeutic drugs. Methods: We investigated the potential herb-drug interactions between BST extract and midazolam (MDZ) in mice...
August 9, 2016: Environmental Health and Toxicology
https://www.readbyqxmd.com/read/27488921/humidfier-disinfectant-case-and-legislative-challenges-of-the-20th-congress
#10
Taehyun Park
A relief system applicable to the damages incurred by the humidifier disinfectants should be revised. It needs to create an institutional environment for the establishment of a risk management system inside corpotate. To this end, intruducing a set of legal systems, including punitive damages, must be reviewed. Also a law should be enacted to impose criminal penalties on the corporate deliberately killing or injuring a person by making reckless decisions. Finally, the government shall change the regulatory framework in a manner that validate that whether the safety check by the corpotrate having or capable of having informations on the products and their composing substances is adequate and sufficient or not...
August 1, 2016: Environmental Health and Toxicology
https://www.readbyqxmd.com/read/26987962/spatial-assessment-of-soil-contamination-by-heavy-metals-from-informal-e-waste-recycling-site-in-agbogbloshie-ghana
#11
Vincent Kyere, Klaus Greve, Sampson Atiemo
Objectives: This study examined the spatial distribution and the extent of soil contamination by heavy metals resulting from the primitive, unconventional informal e-waste recycling in the Agbogbloshie e-waste processing site (AEPS) in Ghana. Method: 132 soil samples were collected at 100 m interval with the aid of a handheld GPS. Observing all procedural and quality assurance measures, the samples were analyzed for barium (Ba), cadmium (Cd), cobalt (Co), chromium (Cr), copper (Cu), mercury (Hg), nickel (Ni), lead (Pb) and zinc (Zn) heavy metals using an X - Ray fluorescence...
March 17, 2016: Environmental Health and Toxicology
https://www.readbyqxmd.com/read/28118702/act-on-the-registration-and-evaluation-of-chemicals-k-reach-and-replacement-reduction-or-refinement-best-practices
#12
REVIEW
Soojin Ha, Troy Seidle, Kyung-Min Lim
OBJECTIVES: Korea's Act on the Registration and Evaluation of Chemicals (K-REACH) was enacted for the protection of human health and the environment in 2015. Considering that about 2000 new substances are introduced annually across the globe, the extent of animal testing requirement could be overwhelming unless regulators and companies work proactively to institute and enforce global best practices to replace, reduce or refine animal use. In this review, the way to reduce the animal use for K-REACH is discussed...
2016: Environmental Health and Toxicology
https://www.readbyqxmd.com/read/28118701/a-study-on-the-factors-affecting-the-follow-up-participation-in-birth-cohorts
#13
Bohyun Park, Eun Jeung Choi, Eunhee Ha, Jong Hyuk Choi, Yangho Kim, Yun-Chul Hong, Mina Ha, Hyesook Park
OBJECTIVES: A stable follow-up participation rate is a very important factor for validity in a cohort study. This study analyzed the factors that affect the participation rate at one hospital-based birth cohort in South Korean. METHODS: The participants were recruited from the Mothers' and Children's Environmental Health study between 2006 and 2010. The analysis targeted 1751 mothers who participated in a birth cohort. We conducted analyses of general characteristics during pregnancy and those of infants at birth that affect the participation rate of the 6-month follow-up survey...
2016: Environmental Health and Toxicology
https://www.readbyqxmd.com/read/27923269/what-must-be-done-to-prevent-another-humidifier-disinfectant-disaster
#14
Jong-Hyeon Lee
The humidifier disinfectant disaster (HDD) was not a simple poisoning accident by biocides, but a singular disaster in history created by chemicals in household products. This disaster was a result of the failure of a system for the management of chemical and product safety. Since the management authority for chemical usage safety is different from those for chemical safety in products, many blind areas for chemical safety management in products still remain. The 'Act on the Registration and Evaluation, etc...
2016: Environmental Health and Toxicology
https://www.readbyqxmd.com/read/27788568/a-cross-sectional-study-of-the-association-between-mobile-phone-use-and-symptoms-of-ill-health
#15
Yong Min Cho, Hee Jin Lim, Hoon Jang, Kyunghee Kim, Jae Wook Choi, Chol Shin, Seung Ku Lee, Jong Hwa Kwon, Nam Kim
OBJECTIVES: This study analyzed the associations between mobile phone call frequency and duration with non-specific symptoms. METHODS: This study was conducted with a population group including 532 non-patient adults established by the Korean Genome and Epidemiology Study. The pattern of phone call using a mobile phone was investigated through face-to-face interview. Structured methods applied to quantitatively assess health effects are Headache Impact Test-6 (HIT-6), Psychosocial Well-being Index-Short Form, Beck Depression Inventory, Korean-Instrumental Activities of Daily Living, Perceived Stress Scale (PSS), Pittsburgh Sleep Quality Index, and 12-item Short Form Health Survey where a higher score represents a higher greater health effect...
2016: Environmental Health and Toxicology
https://www.readbyqxmd.com/read/27756122/a-call-for-action-from-workers-local-residents-and-consumers-a-safe-society-from-toxic-chemicals
#16
Shinbum Kim, Sanghyuk Im, Youngeun Choi, Soomi Park, Jaesoon Hyun, Kyung Seok Lee, Sunimm Lee, Sung-Nan Lee, Jeongri Seo, Ju Hee Kim, Hyunsun Na, Minsun Kim
No abstract text is available yet for this article.
2016: Environmental Health and Toxicology
https://www.readbyqxmd.com/read/27669754/evaluation-of-metal-contamination-and-phytoremediation-potential-of-aquatic-macrophytes-of-east-kolkata-wetlands-india
#17
Amina Khatun, Sandipan Pal, Aloke Kumar Mukherjee, Palas Samanta, Subinoy Mondal, Debraj Kole, Priyanka Chandra, Apurba Ratan Ghosh
OBJECTIVES: The present study analyzes metal contamination in sediment of the East Kolkata Wetlands, a Ramsar site, which is receiving a huge amount of domestic and industrial wastewater from surrounding areas. The subsequent uptake and accumulation of metals in different macrophytes are also examined in regard to their phytoremediation potential. METHODS: Metals like cadmium (Cd), copper (Cu), manganese (Mn), and lead (Pb) were estimated in sediment, water and different parts of the macrophytes Colocasia esculenta and Scirpus articulatus...
2016: Environmental Health and Toxicology
https://www.readbyqxmd.com/read/27431912/major-concerns-regarding-lung-injury-and-related-health-conditions-caused-by-the-use-of-humidifier-disinfectant
#18
Donguk Park
A total of 221 patients were evaluated to be humidifier disinfectant associated with lung injury (HDLI) through two rounds of programs through April 2015. The humidifier disinfectant (HD) brands most often associated with HDLI were found to be Oxy (n=151, 68 %) and Cefu (n=26, 17 %). Polyhexamethylene guanidine used for disinfectant for four types of HD brands including Oxy was found to be associated with the highest number of HDLI cases (n=188). Further programs are operating to identify various health effects including lung injury which may be associated with the use of HD...
2016: Environmental Health and Toxicology
https://www.readbyqxmd.com/read/27384221/an-analysis-of-a-humidifier-disinfectant-case-from-a-toxicological-perspective
#19
Kawangsik Park
An analysis of patients and fatalities due to exposure to polyhexamethylene guanidine (PHMG) shows that PHMG causes mainly lung diseases such as pulmonary fibrosis. However, no research on the other organs has been conducted on this matter yet. So, an in-depth discussion on toxicological techniques is needed to determine whether or not PHMG is toxic to organs other than just the lungs. For the test of target organ toxicity by PHMG exposure, a toxicokinetic study must first be conducted. However, measurement method for PHMG injected into the body has not yet been established because it is not easy to analyze polymer PHMG, so related base studies on analytical technique for PHMG including radio-labeling chemistry must come first...
2016: Environmental Health and Toxicology
https://www.readbyqxmd.com/read/27291945/the-humidifier-disinfectant-scandal-the-need-for-vigorous-government-oversight-of-chemicals-and-household-products-to-secure-public-safety
#20
(no author information available yet)
No abstract text is available yet for this article.
2016: Environmental Health and Toxicology
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