journal
MENU ▼
Read by QxMD icon Read
search

Multiple Sclerosis International

journal
https://www.readbyqxmd.com/read/29721338/decision-making-in-multiple-sclerosis-patients-a-systematic-review
#1
REVIEW
Mireille Neuhaus, Pasquale Calabrese, Jean-Marie Annoni
Background: Multiple sclerosis (MS) is frequently associated with cognitive and behavioural deficits. A growing number of studies suggest an impact of MS on decision-making abilities. The aim of this systematic review was to assess if (1) performance of MS patients in decision-making tasks was consistently different from controls and (2) whether this modification was associated with cognitive dysfunction and emotional alterations. Methods: The search was conducted on Pubmed/Medline database...
2018: Multiple Sclerosis International
https://www.readbyqxmd.com/read/29682349/multiple-sclerosis-patients-with-markedly-low-intrathecal-antibody-response-in-sri-lanka
#2
S M K Gamage, I Wijeweera, S B Adikari, Katharina Fink, Jan Hillert, Anna Fogdell-Hahn, H M A Sominanda
Multiple sclerosis (MS) is a heterogeneous disease which is poorly studied in Asia, where the disease is known to be rare with significant differences in clinical and radiological presentations and intrathecal antibody response. Therefore the objective of this study was to determine clinical presentation, radiological and neurophysiological characteristics, and oligoclonal band status in Sri Lankan MS patients, following careful exclusion of patients with neuromyelitis optica spectrum disorders and other conditions mimicking multiple sclerosis...
2018: Multiple Sclerosis International
https://www.readbyqxmd.com/read/29348937/work-change-in-multiple-sclerosis-as-motivated-by-the-pursuit-of-illness-work-life-balance-a-qualitative-study
#3
Lavanya Vijayasingham, Uma Jogulu, Pascale Allotey
Individuals with multiple sclerosis have a tendency to make early decisions for work change, even in reversible, episodic, or mild disease stages. To better understand how a multiple sclerosis (MS) diagnosis influences perceptions of work and motivations for work changes, we conducted a hermeneutic phenomenology study to explore the work lives of ten individuals with MS in Malaysia. The interpretive analysis and cumulative narratives depict an overarching change in their concept of ideal work and life aspirations and how participants make preemptive work changes to manage illness-work-life futures in subjectively meaningful ways...
2017: Multiple Sclerosis International
https://www.readbyqxmd.com/read/29204297/which-environmental-factor-is-correlated-with-long-term-multiple-sclerosis-incidence-trends-ultraviolet-b-radiation-or-geomagnetic-disturbances
#4
Seyed Aidin Sajedi, Fahimeh Abdollahi
Background: Insufficient received ultraviolet B radiation (UV) is regarded as the main environmental risk factor (RF) for MS in vitamin D deficiency hypothesis. Nevertheless, geomagnetic disturbance (GMD) has also been proposed as a potential trigger for MS in GMD hypothesis. The aim of this study was to investigate which of these mentioned RF is correlated with long-term ultradecadal MS incidence. Methods: After a systematic search, long-term incidence reports of the United Kingdom (UK), Denmark, Tayside County, Nordland County, the Orkney, and Shetland Islands were selected for this retrospective time-series study...
2017: Multiple Sclerosis International
https://www.readbyqxmd.com/read/29181199/the-effects-of-aerobic-exercise-on-the-recovery-of-walking-ability-and-neuroplasticity-in-people-with-multiple-sclerosis-a-systematic-review-of-animal-and-clinical-studies
#5
REVIEW
Augustine Joshua Devasahayam, Matthew Bruce Downer, Michelle Ploughman
Introduction: Walking is of high priority for people with multiple sclerosis (PwMS). It remains unclear whether aerobic exercise can improve walking ability and upregulate neurotrophins. This review aims to consolidate evidence to develop optimal aerobic training parameters to enhance walking outcomes and neuroplasticity in PwMS. Methods: Clinical studies examining aerobic exercise for ≥3 weeks, having outcomes on walking with or without neurotrophic markers, were included...
2017: Multiple Sclerosis International
https://www.readbyqxmd.com/read/29082042/dealing-with-chronic-illness-experiences-of-iranian-families-of-persons-with-multiple-sclerosis-a-qualitative-study
#6
Hossein Ebrahimi, Hadi Hasankhani, Hossein Namdar, Esmail Khodadadi, Marjaneh Fooladi
BACKGROUND: Today family members are providing care and support to each other during illness. In particular, in chronic illness, such as multiple sclerosis, the families are more involved in caring for and supporting their patients, so they use several strategies to cope with this situation. The purpose of this study was to explore the coping strategies in family caregivers of persons with multiple sclerosis in Iran. METHODS: This is a qualitative study that was conducted through 18 family caregivers of persons with multiple sclerosis...
2017: Multiple Sclerosis International
https://www.readbyqxmd.com/read/28900546/short-term-and-long-term-effects-of-an-exercise-based-patient-education-programme-in-people-with-multiple-sclerosis-a-pilot-study
#7
Christina Lutz, Stephanie Kersten, Christian T Haas
Background. Although people with Multiple Sclerosis (pwMS) benefit from physical exercise, they still show reduced physical activity and exercise behaviour. This study aimed to investigate short- and long-term effects of an exercise-based patient education programme (ePEP) that focuses on empowering pwMS to a sustainable and self-regulated exercise training management. Methods. Fourteen pwMS were randomly assigned to immediate experimental group (EG-I: n = 8) and waitlist-control group (EG-W: n = 6) and attended biweekly in a six-week ePEP...
2017: Multiple Sclerosis International
https://www.readbyqxmd.com/read/28804651/pharmacogenetic-biomarkers-to-predict-treatment-response-in-multiple-sclerosis-current-and-future-perspectives
#8
REVIEW
Patricia K Coyle
Disease-modifying therapies (DMTs) have significantly advanced the treatment of relapsing multiple sclerosis (MS), decreasing the frequency of relapses, disability, and magnetic resonance imaging lesion formation. However, patients' responses to and tolerability of DMTs vary considerably, creating an unmet need for biomarkers to identify likely responders and/or those who may have treatment-limiting adverse reactions. Most studies in MS have focused on the identification of pharmacogenetic markers, using either the candidate-gene approach, which requires prior knowledge of the genetic marker and its role in the target disease, or genome-wide association, which examines multiple genetic variants, typically single nucleotide polymorphisms (SNPs)...
2017: Multiple Sclerosis International
https://www.readbyqxmd.com/read/28536657/depression-treatment-among-adults-with-multiple-sclerosis-and-depression-in-ambulatory-care-settings-in-the-united-states
#9
Sandipan Bhattacharjee, Lisa Goldstone, Queeny Ip, Terri Warholak
Background. There is little information regarding depression treatment patterns among adults with MS and depression in ambulatory settings at national level in the United States (US). Objectives. The objectives of this study were to identify patterns and predictors of depression treatment in ambulatory settings in US among adults with MS and depression. Methods. A cross-sectional study was conducted by pooling multiple years (2005-2011) of National Ambulatory Medical Care Survey and the outpatient department of the National Hospital Ambulatory Medical Care Survey data...
2017: Multiple Sclerosis International
https://www.readbyqxmd.com/read/28203460/the-prevalence-of-anti-aquaporin-4-antibody-in-patients-with-idiopathic-inflammatory-demyelinating-diseases-presented-to-a-tertiary-hospital-in-malaysia-presentation-and-prognosis
#10
S Abdullah, W F Wong, C T Tan
Background. There have been inconsistent reports on the prevalence and pathogenicity of anti-Aquaporin 4 (AQP4) in patients presented with idiopathic inflammatory demyelinating diseases (IIDDs). Objective. To estimate the prevalence of anti-AQP4 antibody in patients with IIDDs presented to University Malaya Medical Centre in terms of patients' clinical and radiological presentations and prognoses. Methods. Retrospective data review of IIDDs patients presented from 2005 to 2015. Patients were classified into classical multiple sclerosis (CMS), opticospinal (OS) presentation, optic neuritis (ON), transverse myelitis (TM), brainstem syndrome (BS), and tumefactive MS...
2017: Multiple Sclerosis International
https://www.readbyqxmd.com/read/28116161/the-effect-of-maximal-strength-training-on-strength-walking-and-balance-in-people-with-multiple-sclerosis-a-pilot-study
#11
Herb I Karpatkin, Evan T Cohen, Sarah Klein, David Park, Charles Wright, Michael Zervas
There is little literature examining the use of maximal strength training (MST) in people with multiple sclerosis (pwMS). This pretest-posttest study examined the effects of a MST program on strength, walking, balance, and fatigue in a sample of pwMS. Seven pwMS (median EDSS 3.0, IQR 1.5) participated in a MST program twice weekly for eight weeks. Strength was assessed with 1-repetition maximum (1RM) on each leg. Walking and balance were measured with the 6-Minute Walk Test (6MWT) and Berg Balance Scale (BBS), respectively...
2016: Multiple Sclerosis International
https://www.readbyqxmd.com/read/28116160/free-light-chains-and-intrathecal-b-cells-activity-in-multiple-sclerosis-a-prospective-study-and-meta-analysis
#12
Gabriella Passerini, Gloria Dalla Costa, Francesca Sangalli, Lucia Moiola, Bruno Colombo, Massimo Locatelli, Giancarlo Comi, Roberto Furlan, Vittorio Martinelli
Background. The presence of CSF oligoclonal bands (OBs) is an independent prognostic factor for multiple sclerosis (MS), but the difficulties in the standardization of the test and the interlaboratory variation in reporting have contributed to its limited use in the diagnosis of the disease. Standard nephelometric assays to measure free light chains (FLC) levels have been recently developed and the test may improve the detection of intrathecal B cells activity. Methods. The presence of OBs, kappa and lambda FLC levels, and standard indices of intrathecal inflammation were assessed in 100 consecutive patients, including patients with MS, clinically isolated syndromes (CIS), other inflammatory diseases of the CNS, and other noninflammatory diseases...
2016: Multiple Sclerosis International
https://www.readbyqxmd.com/read/28078140/pregnancy-and-the-use-of-disease-modifying-therapies-in-patients-with-multiple-sclerosis-benefits-versus-risks
#13
REVIEW
Raed Alroughani, Ayse Altintas, Mohammed Al Jumah, Mohammadali Sahraian, Issa Alsharoqi, Abdurahman AlTahan, Abdulkader Daif, Maurice Dahdaleh, Dirk Deleu, Oscar Fernandez, Nikolaos Grigoriadis, Jihad Inshasi, Rana Karabudak, Karim Taha, Natalia Totolyan, Bassem I Yamout, Magd Zakaria, Saeed Bohlega
The burden of multiple sclerosis (MS) in women of childbearing potential is increasing, with peak incidence around the age of 30 years, increasing incidence and prevalence, and growing female : male ratio. Guidelines recommend early use of disease-modifying therapies (DMTs), which are contraindicated or recommended with considerable caution, during pregnancy/breastfeeding. Many physicians are reluctant to prescribe them for a woman who is/is planning to be pregnant. Interferons are not absolutely contraindicated during pregnancy, since interferon- β appears to lack serious adverse effects in pregnancy, despite a warning in its labelling concerning risk of spontaneous abortion...
2016: Multiple Sclerosis International
https://www.readbyqxmd.com/read/28042485/effects-on-balance-and-walking-with-the-coduse-balance-exercise-program-in-people-with-multiple-sclerosis-a-multicenter-randomized-controlled-trial
#14
Anette Forsberg, Lena von Koch, Ylva Nilsagård
Background. Balance and walking impairments are frequent in people with multiple sclerosis (MS). Objective. The aim was to investigate the effects of a group-based balance exercise program targeting core stability, dual tasking, and sensory strategies (CoDuSe) on balance, postural sway, walking, perceived walking limitations, and balance confidence. Design. A single-blinded randomized multicenter trial. No intervention was given to controls. Participants. People with MS able to walk 100 meters but unable to maintain tandem stance ≥30 seconds...
2016: Multiple Sclerosis International
https://www.readbyqxmd.com/read/27563466/evasep-a-noninterventional-study-describing-the-perception-of-neurologists-patients-and-caregivers-on-caregivers-role-in-the-support-of-patients-suffering-from-multiple-sclerosis-treated-with-subcutaneous-interferon-beta-1a
#15
Cécile Donzé, Bruno Lenne, Anne-Sophie Jean Deleglise, Christian Kempf, Yasmine Bellili, Patrick Hautecoeur
Background. The perception of the role of caregivers for people with multiple sclerosis (MS) is important but poorly studied, particularly in patients with low levels of disability. Objectives. To describe the perceptions of the role of caregivers from the perspective of the caregiver, the patient, and neurologists. Methods. This observational study was conducted in France on patients with relapsing remitting MS treated with subcutaneous (SC) interferon-β-1a (IFN-β-1a) for more than 24 months. Results. Caregiver, patients, and neurologists all considered providing moral support and fighting against the disease as the most important role of the care provider...
2016: Multiple Sclerosis International
https://www.readbyqxmd.com/read/27529034/retracted-consensus-guidelines-for-csf-and-blood-biobanking-for-cns-biomarker-studies
#16
Multiple Sclerosis International
[This retracts the article DOI: 10.1155/2011/246412.].
2016: Multiple Sclerosis International
https://www.readbyqxmd.com/read/27504201/healthy-aging-from-the-perspectives-of-683-older-people-with-multiple-sclerosis
#17
Elizabeth M Wallack, Hailey D Wiseman, Michelle Ploughman
Purpose. The aim of this study was to determine what factors most greatly contributed to healthy aging with multiple sclerosis (MS) from the perspective of a large sample of older people with MS. Design and Methods. Participants (n = 683; >55 years of age with symptoms >20 years) provided answers to an open-ended question regarding healthy aging and were categorized into three groups, 55-64 (young), 65-74 (middle), and 75 and over (oldest old). Sociodemographic actors were compared using ANOVA. Two independent raters used the framework method of analyzing qualitative data...
2016: Multiple Sclerosis International
https://www.readbyqxmd.com/read/27382489/the-incidence-of-euphoria-in-multiple-sclerosis-artefact-of-measure
#18
Amy Duncan, Susan Malcolm-Smith, Ozayr Ameen, Mark Solms
Background. A subgroup of MS patients present with "euphoria." Classical authors describe this symptom as the predominant mood state of these patients, while contemporary authors regard it as rare. Objective. This study aimed to address these discrepancies and investigate the contributions made by varying operational definitions and measurement instruments. Methods. One hundred MS patients and 100 matched controls completed the classical interview of Cottrell and Wilson and the modern Neuropsychiatric Inventory in a once-off interview...
2016: Multiple Sclerosis International
https://www.readbyqxmd.com/read/27200190/the-efficacy-of-functional-electrical-stimulation-of-the-abdominal-muscles-in-the-treatment-of-chronic-constipation-in-patients-with-multiple-sclerosis-a-pilot-study
#19
Christine Singleton, Abdel Magid Bakheit, Carla Peace
Chronic constipation in patients with multiple sclerosis (MS) is common and the current methods of treatment are ineffective in some patients. Anecdotal observations suggest that functional electrical stimulation (FES) of the abdominal muscles may be effective in the management of constipation in these patients. Patients and Methods. In this exploratory investigation we studied the effects of FES on the whole gut transit time (WGTT) and the colonic transit time (CTT). In addition, we evaluated the treatment effect on the patients' constipation-related quality of life and on the use of laxatives and the use of manual bowel evacuation...
2016: Multiple Sclerosis International
https://www.readbyqxmd.com/read/26966579/management-of-multiple-sclerosis-in-the-breastfeeding-mother
#20
REVIEW
Saneea Almas, Jesse Vance, Teresa Baker, Thomas Hale
Multiple Sclerosis (MS) is an autoimmune neurological disease characterized by inflammation of the brain and spinal cord. Relapsing-Remitting MS is characterized by acute attacks followed by remission. Treatment is aimed at halting these attacks; therapy may last for months to years. Because MS disproportionately affects females and commonly begins during the childbearing years, clinicians treat pregnant or nursing MS patients. The intent of this review is to perform an in-depth analysis into the safety of drugs used in breastfeeding women with MS...
2016: Multiple Sclerosis International
journal
journal
43705
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"