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Nutrition & Diabetes

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https://www.readbyqxmd.com/read/28394365/olive-oil-in-the-prevention-and-management-of-type-2-diabetes-mellitus-a-systematic-review-and-meta-analysis-of-cohort-studies-and-intervention-trials
#1
L Schwingshackl, A-M Lampousi, M P Portillo, D Romaguera, G Hoffmann, H Boeing
BACKGROUND/OBJECTIVES: Olive oil (OO) as food is composed mainly of fatty acids and bioactive compounds depending from the extraction method. Both had been discussed as health promoting with still open questions. Thus, we conducted a meta-analysis to illustrate the impact of this food on type 2 diabetes (T2D) by investigating the association between OO intake and risk of T2D, and the effect of OO intake in the management of T2D. SUBJECTS/METHODS: Searches were performed in PubMed, Cochrane Library and google scholar...
April 10, 2017: Nutrition & Diabetes
https://www.readbyqxmd.com/read/28394364/human-adipose-tissue-accumulation-is-associated-with-pro-inflammatory-changes-in-subcutaneous-rather-than-visceral-adipose-tissue
#2
I Kralova Lesna, S Cejkova, A Kralova, J Fronek, M Petras, A Sekerkova, F Thieme, L Janousek, R Poledne
The importance of the involvement of adipose tissue macrophage subpopulations in obesity-related disorders is well known from different animal models, but human data are scarcer. Subcutaneous (n=44) and visceral (n=52) adipose tissues of healthy living kidney donors were obtained during living donor nephrectomy. Stromal vascular fractions were isolated and analysed by flow cytometry using CD14, CD16, CD36 and CD163 antibodies. Total macrophage numbers in subcutaneous adipose tissue increased (P=0.02) with body mass index (BMI), with a similar increase seen in the proportion of phagocytic CD14+CD16+CD36(high) macrophages (P<0...
April 10, 2017: Nutrition & Diabetes
https://www.readbyqxmd.com/read/28394363/interleukin-18-mediates-cardiac-dysfunction-induced-by-western-diet-independent-of-obesity-and-hyperglycemia-in-the-mouse
#3
S Carbone, P J H Lee, A G Mauro, E Mezzaroma, R Buzzetti, B Van Tassell, A Abbate, S Toldo
Obesity and diabetes are independent risk factors for heart failure and are associated with the consumption of diet rich in saturated fat and sugar, Western diet (WD), known to induce cardiac dysfunction in the mouse through incompletely characterized inflammatory mechanisms. We hypothesized that the detrimental cardiac effects of WD are mediated by interleukin-18 (IL-18), pro-inflammatory cytokine linked to cardiac dysfunction. C57BL/6J wild-type male mice and IL-18 knockout male mice were fed high-saturated fat and high-sugar diet for 8 weeks...
April 10, 2017: Nutrition & Diabetes
https://www.readbyqxmd.com/read/28394362/prevalence-of-vitamin-d-deficiency-and-association-with-metabolic-syndrome-in-a-qatari-population
#4
K Al-Dabhani, K K Tsilidis, N Murphy, H A Ward, P Elliott, E Riboli, M Gunter, I Tzoulaki
OBJECTIVES: Despite long hours of sunlight in Qatar and other regions of the Middle East, vitamin D deficiency has been rising. In parallel, the prevalence of metabolic syndrome has also been increasing in Qatar. Vitamin D levels have been associated with metabolic syndrome but the data are inconsistent and no studies have addressed these inter-relationships in a Middle Eastern population where the prevalence of these conditions is high. The objective is to investigate the prevalence of vitamin D deficiency and its association with metabolic syndrome and its components in the Qatar Biobank population...
April 10, 2017: Nutrition & Diabetes
https://www.readbyqxmd.com/read/28394361/effects-of-walnut-oil-on-lipid-profiles-in-hyperlipidemic-type-2-diabetic-patients-a-randomized-double-blind-placebo-controlled-trial
#5
M J Zibaeenezhad, P Farhadi, A Attar, A Mosleh, F Amirmoezi, A Azimi
BACKGROUND: The role of herbal medicine is now well documented in preventing and controlling diabetes mellitus. The main aim of this study was to evaluate the effects of walnut oil consumption on lipid profiles of hyperlipidemic patients with type 2 diabetes. METHODS: In a randomized, double-blind, placebo-controlled clinical trial, 100 hyperlipidemic type 2 diabetic patients aged 35-75 years were assigned to receive 15 cc Persian walnut oil or placebo every day for 90 days...
April 10, 2017: Nutrition & Diabetes
https://www.readbyqxmd.com/read/28394360/differential-sympathetic-outflow-to-adipose-depots-is-required-for-visceral-fat-loss-in-response-to-calorie-restriction
#6
L M Sipe, C Yang, J Ephrem, E Garren, J Hirsh, C D Deppmann
The sympathetic nervous system (SNS) regulates energy homeostasis in part by governing fatty acid liberation from adipose tissue. We first examined whether SNS activity toward discrete adipose depots changes in response to a weight loss diet in mice. We found that SNS activity toward each adipose depot is unique in timing, pattern of activation, and habituation with the most dramatic contrast between visceral and subcutaneous adipose depots. Sympathetic drive toward visceral epididymal adipose is more than doubled early in weight loss and then suppressed later in the diet when weight loss plateaued...
April 10, 2017: Nutrition & Diabetes
https://www.readbyqxmd.com/read/28394359/the-role-of-sex-and-body-weight-on-the-metabolic-effects-of-high-fat-diet-in-c57bl-6n-mice
#7
C Ingvorsen, N A Karp, C J Lelliott
BACKGROUND: Metabolic disorders are commonly investigated using knockout and transgenic mouse models on the C57BL/6N genetic background due to its genetic susceptibility to the deleterious metabolic effects of high-fat diet (HFD). There is growing awareness of the need to consider sex in disease progression, but limited attention has been paid to sexual dimorphism in mouse models and its impact in metabolic phenotypes. We assessed the effect of HFD and the impact of sex on metabolic variables in this strain...
April 10, 2017: Nutrition & Diabetes
https://www.readbyqxmd.com/read/28319109/the-broad-study-a-randomised-controlled-trial-using-a-whole-food-plant-based-diet-in-the-community-for-obesity-ischaemic-heart-disease-or-diabetes
#8
N Wright, L Wilson, M Smith, B Duncan, P McHugh
BACKGROUND/OBJECTIVE: There is little randomised evidence using a whole food plant-based (WFPB) diet as intervention for elevated body mass index (BMI) or dyslipidaemia. We investigated the effectiveness of a community-based dietary programme. Primary end points: BMI and cholesterol at 6 months (subsequently extended). SUBJECTS: Ages 35-70, from one general practice in Gisborne, New Zealand. Diagnosed with obesity or overweight and at least one of type 2 diabetes, ischaemic heart disease, hypertension or hypercholesterolaemia...
March 20, 2017: Nutrition & Diabetes
https://www.readbyqxmd.com/read/28319108/evaluation-of-serum-zonulin-for-use-as-an-early-predictor-for-gestational-diabetes
#9
K Mokkala, K Tertti, T Rönnemaa, T Vahlberg, K Laitinen
Diet has an important role in regulating intestinal permeability and subsequently the risk for metabolic disorders. In this observational study, we examined whether serum intestinal permeability marker zonulin, could be used as a predictor for gestational diabetes mellitus (GDM). Serum zonulin concentration was measured in early pregnancy in overweight or obese pregnant women (n=88) at risk for developing GDM. Serum zonulin was associated with higher odds of GDM (adjusted OR for 1 ng ml(-1) increase in zonulin: 1...
March 20, 2017: Nutrition & Diabetes
https://www.readbyqxmd.com/read/28319107/long-term-weight-change-slope-weight-fluctuation-and-risk-of-type-2-diabetes-mellitus-in-middle-aged-japanese-men-and-women-findings-of-aichi-workers-cohort-study
#10
Y Zhang, H Yatsuya, Y Li, C Chiang, Y Hirakawa, N Kawazoe, K Tamakoshi, H Toyoshima, A Aoyama
OBJECTIVE: This study aims to investigate the association of long-term weight-change slopes, weight fluctuation and the risk of type 2 diabetes mellitus (T2DM) in middle-aged Japanese men and women. METHODS: A total of 4234 participants of Aichi Workers' Cohort Study who were aged 35-66 years and free of diabetes in 2002 were followed through 2014. Past body weights at the ages of 20, 25, 30, 40 years, and 5 years before baseline as well as measured body weight at baseline were regressed on the ages...
March 20, 2017: Nutrition & Diabetes
https://www.readbyqxmd.com/read/28319106/a-systematic-review-on-the-impact-of-diabetes-mellitus-on-the-ocular-surface
#11
REVIEW
K Co Shih, K S-L Lam, L Tong
Diabetes mellitus is associated with extensive morbidity and mortality in any human community. It is well understood that the burden of diabetes is attributed to chronic progressive damage in major end-organs, but it is underappreciated that the most superficial and transparent organ affected by diabetes is the cornea. Different corneal components (epithelium, nerves, immune cells and endothelium) underpin specific systemic complications of diabetes. Just as diabetic retinopathy is a marker of more generalized microvascular disease, corneal nerve changes can predict peripheral and autonomic neuropathy, providing a window of opportunity for early treatment...
March 20, 2017: Nutrition & Diabetes
https://www.readbyqxmd.com/read/28319105/link-of-dietary-patterns-with-metabolic-syndrome-analysis-of-the-national-health-and-nutrition-examination-survey
#12
M Mazidi, S Pennathur, F Afshinnia
BACKGROUND: Population-based interventions aimed at halting the increasing prevalence of metabolic syndrome (MetS) require thorough understanding of dietary interplays. Objective is to identify the independent dietary nutrients associated with MetS and its components using dietary pattern identification and the single-nutrient approaches in The United States. METHODS: This is a cross-sectional observation. Participants are selected from the National Health and Nutrition Examination Survey (NHANES) with available dietary intake, biochemical and anthropometrical data from 2001 to 2012...
March 20, 2017: Nutrition & Diabetes
https://www.readbyqxmd.com/read/28319104/diabetes-consequences-in-the-fetus-liver-of-the-non-obese-diabetic-mice
#13
M B Aires, A C V Dos Santos, M S Kubrusly, A C de Lima Luna, L A C D'Albuquerque, D A Maria
DM type 1 (T1D) incidence is increasing around 3% every year and represents risks for maternal and fetal health. The objective of this study was to explore the effects of diabetes on fetus liver cells in non-obese diabetic (NOD) mice. Hyperglycemic NOD (HNOD), normoglycemic NOD (NNOD) and BALB/c females were used for mating, and the fetus livers were collected at 19.5 gestation day (gd). HNOD group had reduced fetal weight (989.5±68.32 vs 1290±57.39 mg BALB/c, P<0.05) at 19.5 gd and higher glycemia (516...
March 20, 2017: Nutrition & Diabetes
https://www.readbyqxmd.com/read/28319103/microglia-activation-due-to-obesity-programs-metabolic-failure-leading-to-type-two-diabetes
#14
REVIEW
R Maldonado-Ruiz, L Montalvo-Martínez, L Fuentes-Mera, A Camacho
Obesity is an energy metabolism disorder that increases susceptibility to the development of metabolic diseases. Recently, it has been described that obese subjects have a phenotype of chronic inflammation in organs that are metabolically relevant for glucose homeostasis and energy. Altered expression of immune system molecules such as interleukins IL-1, IL-6, IL-18, tumor necrosis factor alpha (TNF-α), serum amyloid A (SAA), and plasminogen activator inhibitor-1 (PAI-1), among others, has been associated with the development of chronic inflammation in obesity...
March 20, 2017: Nutrition & Diabetes
https://www.readbyqxmd.com/read/28319102/malnutrition-and-non-communicable-diseases-among-bangladeshi-women-an-urban-rural-comparison
#15
M S Zahangir, M M Hasan, A Richardson, S Tabassum
BACKGROUND/OBJECTIVES: This study aims at examining the urban-rural differentials in the effects of socioeconomic predictors on underweight and obesity of ever-married women in Bangladesh. The effect of malnutrition and other risk factors on non-communicable diseases is also examined. SUBJECTS/METHODS: The information regarding nutritional status, socioeconomic and demographic background, and non-communicable diseases of ever-married women was extracted from the nationally representative, cross-sectional Bangladesh Demographic and Health Survey (BDHS 2011) data set...
March 20, 2017: Nutrition & Diabetes
https://www.readbyqxmd.com/read/28287631/negative-association-between-acrylamide-exposure-and-body-composition-in-adults-nhanes-2003-2004
#16
P-L Chu, L-Y Lin, P-C Chen, T-C Su, C-Y Lin
BACKGROUND/OBJECTIVES: Acrylamide is present in mainstream cigarette smoke and in some food prepared at high temperature. Animal studies have shown that acrylamide exposure reduces body weight. Prenatal exposure to acrylamide also has been linked to reduced birth weight in human. Whether acrylamide exposure is associated with altered body compositions in adults is not clear. SUBJECTS/METHODS: We selected 3623 subjects (aged ⩾20 years) from a National Health and Nutrition Examination Survey (NHANES) in 2003-2004 to determine the relationship among hemoglobin adducts of acrylamide (HbAA), hemoglobin adducts of glycidamide (HbGA) and body composition (body measures, bioelectrical impedance analysis (BIA), dual energy x-ray absorptiometry (DXA))...
March 13, 2017: Nutrition & Diabetes
https://www.readbyqxmd.com/read/28287630/overweight-and-obesity-in-mexican-children-and-adolescents-during-the-last-25-years
#17
S Hernández-Cordero, L Cuevas-Nasu, M C Morán-Ruán, I Méndez-Gómez Humarán, M A Ávila-Arcos, J A Rivera-Dommarco
BACKGROUND/OBJECTIVE: The objective of the study was to provide current estimates of the prevalence and trends of overweight and obesity (OW+OB) in Mexican children and adolescents. SUBJECTS/METHODS: Body mass index objectively measured was analyzed for 37 147 children and adolescents aged 0-19 years obtained in 2012 as part of the National Health and Nutrition Survey (ENSANUT-2012), a nationally representative sample of the Mexican population. In addition, data from previous National Nutrition Surveys obtained in 1988, 1999 and 2006 were compared with analyze trends over a 24-year period (1988-2012) for children <5 years of age and adolescents and over a 13-year period (1999-2012) for school-age children...
March 13, 2017: Nutrition & Diabetes
https://www.readbyqxmd.com/read/28287629/metabolic-disturbances-due-to-a-high-fat-diet-in-a-non-insulin-resistant-animal-model
#18
L Ramalho, M N da Jornada, L C Antunes, M P Hidalgo
OBJECTIVE: Shift workers have metabolic changes more often than day workers. It is also known that night workers prefer foods high in saturated fat. Such data suggest that shift workers are prone to cardiovascular disease. Therefore, the objective of this study was to propose an animal model to test the effect of high-fat diet (HFD) based on shift workers' diet. METHODS: This is an experimental study with 20 Wistar rats. Ten rats were allocated to the control group (CG) and were fed standard diet...
March 13, 2017: Nutrition & Diabetes
https://www.readbyqxmd.com/read/28287628/prevalence-of-hypovitaminosis-d-and-associated-factors-in-obese-spanish-children
#19
T Durá-Travé, F Gallinas-Victoriano, M J Chueca-Guindulain, S Berrade-Zubiri
BACKGROUND/OBJECTIVES: Vitamin D deficiency may contribute to endocrine health and disease (diabetes, autoimmune thyroid diseases, polycystic ovarian syndrome, etc.). The aim of this study was to determine the prevalence and specific factors for hypovitaminosis D among children stratified by body mass index (BMI) in Northern Spain. SUBJECTS/METHODS: A cross-sectional clinical (sex, age, season of study visit, place of residence and BMI) and blood testing (calcium, phosphorous, calcidiol and parathyroid hormone (PTH)) were accomplished in 546 Caucasian individuals (aged 3...
March 13, 2017: Nutrition & Diabetes
https://www.readbyqxmd.com/read/28287627/plasma-free-amino-acid-profiles-are-predictors-of-cancer-and-diabetes-development
#20
REVIEW
X Bi, C J Henry
Type 2 diabetes (T2D) and cancers are two major causes of morbidity and mortality worldwide. Nowadays, there is convincing evidence of positive associations between T2D and the incidence or prognosis of a wide spectrum of cancers, for example, breast, colon, liver and pancreas. Many observational studies suggest that certain medications used to treat hyperglycemia (or T2D) may affect cancer cells directly or indirectly. The potential mechanisms of the direct T2D cancer links have been hypothesized to be hyperinsulinemia, hyperglycemia and chronic inflammation; however, the metabolic pathways that lead to T2D and cancers still remain elusive...
March 13, 2017: Nutrition & Diabetes
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