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International Journal of Surgical Oncology

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https://www.readbyqxmd.com/read/29568650/radical-gastrectomy-still-the-cornerstone-of-curative-treatment-for-gastric-cancer-in-the-perioperative-chemotherapy-era-a-single-institute-experience-over-a-decade
#1
Harsh Kanhere, Raghav Goel, Ben Finlay, Markus Trochsler, Guy Maddern
Background and Objectives: Most gastric cancer patients now undergo perioperative chemotherapy (POCT) based on the MAGIC trial results. POCT consists of neoadjuvant chemotherapy (NACT) as well as postoperative adjuvant chemotherapy. This study assessed the applicability of perioperative chemotherapy and the impact of radical gastrectomy encompassing a detailed lymph-node resection on outcomes of gastric cancer. Methods: Medical and pathology records of all gastric carcinoma resections were reviewed from 2006 onwards...
2018: International Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29387486/treatment-outcome-of-carcinoma-vulva-ten-year-experience-from-a-tertiary-cancer-centre-in-south-india
#2
Sakthiushadevi Jeevarajan, Amudhan Duraipandian, Rajkumar Kottayasamy Seenivasagam, Subbiah Shanmugam, Rajaraman Ramamurthy
Background: Carcinoma vulva is a rare disease accounting for 1.3% of all gynaecological malignancies. The present study is a 10-year retrospective review of our experience of the surgical options, morbidity, failure pattern, and survival for invasive carcinoma vulva. Materials and Methods: Retrospective analysis of case records of 39 patients who underwent surgery for invasive vulval cancer between 2004 and 2013 in the Department of Surgical Oncology at the Government Royapettah Hospital, Chennai...
2017: International Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29234525/invasive-candida-infection-after-upper-gastrointestinal-tract-surgery-for-gastric-cancer
#3
Evgeni Brotfain, Gilbert Sebbag, Michael Friger, Boris Kirshtein, Abraham Borer, Leonid Koyfman, Dmitry Frank, Yoav Bichovsky, Jochanan G Peiser, Moti Klein
Upper gastrointestinal tract (GIT) surgical procedures are more likely to cause nosocomial Candida peritonitis than lower GIT procedures and they thus constitute an independent risk factor for mortality. Because of the severity of postsurgical fungal infections complications, intensivists and surgeons need to be extremely aware of their clinical importance in critically ill postsurgical intensive care unit (ICU) patients. We analyzed the clinical and microbiological data of 149 oncologic patients who were hospitalized in the ICU at Soroka Medical Center between January 2010 and January 2015 after undergoing upper GIT surgery for gastric cancer...
2017: International Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28798875/pancreatogastrostomy-versus-pancreatojejunostomy-an-up-to-date-meta-analysis-of-rcts
#4
REVIEW
Konstantinos Perivoliotis, Eleni Sioka, Athina Tatsioni, Ioannis Stefanidis, Elias Zintzaras, Dimitrios Zacharoulis
BACKGROUND: A meta-analysis was conducted in order to provide an up-to-date comparison of pancreatogastrostomy (PG) and pancreatojejunostomy (PJ), after pancreatoduodenectomy (PD), in terms of clinically significant postoperative pancreatic fistula (POPF) and other postoperative complications. METHODS: This meta-analysis was conducted according to the PRISMA guidelines and the Cochrane Handbook for Systematic Reviews of Interventions. A systematic literature search in MEDLINE and Cochrane Central Register of Controlled Clinical Trials was performed...
2017: International Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28798874/results-from-survey-to-assess-current-trends-in-surgical-practice-in-the-management-of-women-with-early-stage-cervical-cancer-within-the-bgcs-community-with-an-emphasis-on-routine-frozen-section-examination
#5
Kumar Gubbala, Alexandros Laios, Thulumuru Kavitha Madhuri, Pubudu Pathiraja, Krishnayan Haldar, Sean Kehoe
In the UK, more than 3,200 new cases of cervical cancer are diagnosed each year. Early stage cervical cancer (IA2-IB1) treatment comprises central surgery mainly in the form of radical hysterectomy or fertility sparing surgery including trachelectomy as well as systematic pelvic lymphadenectomy to detect metastases and adjust treatment accordingly. Given the variation in determining the lymph node (LN) status, a major prognosticator, we reviewed the current UK practice of LN assessment in women undergoing surgery for early cervical cancer...
2017: International Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28761765/endoscopic-stenting-as-bridge-to-surgery-versus-emergency-resection-for-left-sided-malignant-colorectal-obstruction-an-updated-meta-analysis
#6
REVIEW
Niccolò Allievi, Marco Ceresoli, Paola Fugazzola, Giulia Montori, Federico Coccolini, Luca Ansaloni
INTRODUCTION: Emergency resection represents the traditional treatment for left-sided malignant obstruction. However, the placement of self-expanding metallic stents and delayed surgery has been proposed as an alternative approach. The aim of the current meta-analysis was to review the available evidence, with particular interest for the short-term outcomes, including a recent multicentre RCT. METHODS: We considered randomized controlled trials comparing stenting as a bridge to surgery and emergency surgery for the management of left-sided malignant large bowel obstruction, performing a systematic review in MEDLINE, PubMed database, and the Cochrane libraries...
2017: International Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28751990/dermal-substitutes-use-in-reconstructive-surgery-for-skin-tumors-a-single-center-experience
#7
Mariane Campagnari, Andrea S Jafelicci, Helio A Carneiro, Eduard R Brechtbühl, Eduardo Bertolli, João P Duprat Neto
Reconstructive surgery following skin tumor resection can be challenging. Treatment options after removing the tumor are skin grafting, local pedicled and axial flaps, or microsurgery for complex and extensive wounds correction. Recently, the use of dermal substitutes has been extended to reconstructive surgery in cutaneous oncology. Objectives. To report both a single-center experience using dermal substitutes in reconstructive surgery for skin malignancies and reconstructive surgery's outcomes. Methods and Results...
2017: International Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28751989/en-bloc-pancreaticoduodenectomy-for-locally-advanced-right-colon-cancers
#8
Cihan Ağalar, Aras Emre Canda, Tarkan Unek, Selman Sokmen
Locally advanced right colon cancer may invade adjacent tissue and organs. Direct invasion of the duodenum and pancreas necessitates an en bloc resection. Previously, this challenging procedure was associated with high morbidity and mortality; however, today, this procedure can be done more safely in experienced centers. The aim of this study is to report our experience on en bloc right colectomy with pancreaticoduodenectomy for locally advanced right colon cancers. Between 2000 and 2012, 5 patients underwent en bloc multivisceral resection...
2017: International Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28593056/management-options-for-advanced-low-or-intermediate-grade-gastroenteropancreatic-neuroendocrine-tumors-review-of-recent-literature
#9
REVIEW
Vladimir Neychev, Electron Kebebew
Our understanding of the biology, genetics, and natural history of neuroendocrine tumors (NETs) of the gastrointestinal tract and pancreas has improved considerably in the last several decades and the spectrum of available therapeutic options is rapidly expanding. The management of patients with metastatic low or intermediate grade NETs has been revolutionized by the development of new treatment strategies such as molecular targeting therapies with everolimus and sunitinib, somatostatin analogs, tryptophan hydroxylase inhibitors, and peptide receptor radionuclide therapy that can be used alone or as a multimodal approach with or without surgery...
2017: International Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28487771/noninvasive-encapsulated-follicular-variant-of-papillary-thyroid-cancer-clinical-lessons-from-a-community-based-endocrine-surgical-practice
#10
Allan Golding, Dana Shively, David N Bimston, R Mack Harrell
Objective. Retrospective studies have found that noninvasive encapsulated follicular variant of papillary thyroid cancer (EFVPTC) exhibits highly indolent clinical behavior. We studied the clinical features of our patients with noninvasive EFVPTC tumors culled from a community endocrine surgical practice registry over the past four years. Methods. We interrogated the Memorial Center for Integrative Endocrine Surgery (MCIES) Registry for all recorded encapsulated follicular variant of papillary cancer pathologic diagnoses...
2017: International Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28058117/the-role-of-18-f-fdg-pet-ct-in-predicting-malignant-transformation-of-plexiform-neurofibromas-in-neurofibromatosis-1
#11
REVIEW
David Tovmassian, Muzib Abdul Razak, Kevin London
Background. Malignant peripheral nerve sheath tumours (MPNSTs) are difficult to diagnose and treat and contribute to significant morbidity and mortality for patients with Neurofibromatosis-1 (NF-1). FDG-PET/CT is being increasingly used as an imaging modality to discriminate between benign and malignant plexiform neurofibromas. Objectives. To assess the value of FDG-PET/CT in differentiating between benign and malignant peripheral nerve lesions for patients with Neurofibromatosis-1. Methods. A systematic review of the literature was performed prior to application of stringent selection criteria...
2016: International Journal of Surgical Oncology
https://www.readbyqxmd.com/read/27803813/preoperative-radiation-therapy-followed-by-reexcision-may-improve-local-control-and-progression-free-survival-in-unplanned-excisions-of-soft-tissue-sarcomas-of-the-extremity-and-chest-wall
#12
COMPARATIVE STUDY
Hina Saeed, David M King, Candice A Johnstone, John A Charlson, Donald A Hackbarth, John C Neilson, Manpreet Bedi
Background. The management for unplanned excision (UE) of soft tissue sarcomas (STS) has not been established. In this study, we compare outcomes of UE versus planned excision (PE) and determine an optimal treatment for UE in STS. Methods. From 2000 to 2014 a review was performed on all patients treated with localized STS. Clinical outcomes including local recurrence-free survival (LRFS), progression-free survival (PFS), and overall survival (OS) were evaluated using the Kaplan-Meier estimate. Univariate (UVA) and multivariate (MVA) analyses were performed to determine prognostic variables...
2016: International Journal of Surgical Oncology
https://www.readbyqxmd.com/read/27747102/neoadjuvant-therapy-in-differentiated-thyroid-cancer
#13
REVIEW
Rajan P Dang, Daniel McFarland, Valerie H Le, Nadia Camille, Brett A Miles, Marita S Teng, Eric M Genden, Krzysztof J Misiukiewicz
Objectives. Invasion of differentiated thyroid cancer (DTC) into surrounding structures can lead to morbid procedures such as laryngectomy and tracheal resection. In these patients, there is a potential role for neoadjuvant therapy. Methods. We identified three studies involving the treatment of DTC with neoadjuvant chemotherapy: two from Slovenia and one from Japan. Results. These studies demonstrate that in selected situations, neoadjuvant chemotherapy can have a good response and allow for a more complete surgical resection, the treatment of DTC...
2016: International Journal of Surgical Oncology
https://www.readbyqxmd.com/read/27190644/liposarcoma-of-the-spermatic-cord-impact-of-final-surgical-intervention-an-institutional-experience
#14
R Bachmann, J Rolinger, P Girotti, H G Kopp, K Heissner, B Amend, A Königsrainer, R Ladurner
BACKGROUND: Paratesticular liposarcomas are almost always mistakenly diagnosed as inguinal hernias subsequently followed by inadequate operation. METHODS: 14 consecutive patients with paratesticular liposarcoma were retrospectively reviewed. Preoperative management was evaluated. Disease-free and overall survival were determined. RESULTS: In 11 patients primary and in 3 patients recurrent liposarcoma of the spermatic cord were diagnosed. Regarding primary treatment in primary surgical intervention resection was radical (R0) in 7 of 14 (50%) patients, marginal (R1) in 6 (43%) patients, and incomplete with macroscopic residual tumour (R2) in 1 (7%) patient...
2016: International Journal of Surgical Oncology
https://www.readbyqxmd.com/read/27110398/current-practice-of-therapeutic-mammaplasty-a-survey-of-oncoplastic-breast-surgeons-in-england
#15
Shweta Aggarwal, Sekhar Marla, Donald Nyanhongo, Sita Kotecha, Narendra Nath Basu
INTRODUCTION: Therapeutic mammaplasty (TM) is a useful technique in the armamentarium of the oncoplastic breast surgeon (OBS). There is limited guidance on patient selection, technique, coding, and management of involved margins. The practices of OBS in England remain unknown. METHODS: Questionnaires were sent to all OBS involved with the Training Interface Group. We assessed the number of TM cases performed per surgeon, criteria for patient selection, pedicle preference, contralateral symmetrisation, use of routine preoperative MRI, management of involved margins, and clinical coding...
2016: International Journal of Surgical Oncology
https://www.readbyqxmd.com/read/27034826/a-structured-assessment-to-decrease-the-amount-of-inconclusive-endometrial-biopsies-in-women-with-postmenopausal-bleeding
#16
M C Breijer, N C M Visser, N van Hanegem, A A van der Wurff, B C Opmeer, H C van Doorn, B W J Mol, J M A Pijnenborg, A Timmermans
OBJECTIVE: To determine whether structured assessment of outpatient endometrial biopsies decreases the number of inconclusive samples. DESIGN: Retrospective cohort study. SETTING: Single hospital pathology laboratory. POPULATION: Endometrial biopsy samples of 66 women with postmenopausal bleeding, collected during the usual diagnostic work-up and assessed as insufficient for a reliable histological diagnosis. METHODS: Endometrial biopsy samples were requested from the pathology laboratories...
2016: International Journal of Surgical Oncology
https://www.readbyqxmd.com/read/27006828/prognostic-relevance-of-the-peritoneal-surface-disease-severity-score-compared-to-the-peritoneal-cancer-index-for-colorectal-peritoneal-carcinomatosis
#17
COMPARATIVE STUDY
Jia Lin Ng, Whee Sze Ong, Claramae Shulyn Chia, Grace Hwei Ching Tan, Khee-Chee Soo, Melissa Ching Ching Teo
BACKGROUND: Peritoneal Carcinomatosis Index (PCI) is a widely established scoring system that describes disease burden in isolated colorectal peritoneal carcinomatosis (CPC). Its significance may be diminished with complete cytoreduction. We explore the utility of the recently described Peritoneal Surface Disease Severity Score (PSDSS) and compare its prognostic value against PCI. METHODS: The endpoints were overall survival (OS), progression-free survival (PFS), and survival less than 18 months (18 MS)...
2016: International Journal of Surgical Oncology
https://www.readbyqxmd.com/read/26989509/a-review-of-the-literature-on-extrarenal-retroperitoneal-angiomyolipoma
#18
REVIEW
Anthony Kodzo-Grey Venyo
BACKGROUND: Extrarenal retroperitoneal angiomyolipomas are rare. AIM: To review the literature. RESULTS: Angiomyolipomas, previously classified as hamartomas, are now classified as benign tumours. Thirty cases of primary retroperitoneal angiomyolipomas have been reported. Diagnosis of the disease upon is based radiological and pathological findings of triphasic features of (a) fat and (b) blood vessels and myoid tissue. Immunohistochemistry tends to be positive for HMB45, MART1, HHF35, calponin, NKI-C3, and CD117...
2016: International Journal of Surgical Oncology
https://www.readbyqxmd.com/read/26955484/neoadjuvant-chemotherapy-in-locally-advanced-and-borderline-resectable-nonsquamous-sinonasal-tumors-esthesioneuroblastoma-and-sinonasal-tumor-with-neuroendocrine-differentiation
#19
Vijay M Patil, Amit Joshi, Vanita Noronha, Vibhor Sharma, Saurabh Zanwar, Sachin Dhumal, Shubhada Kane, Prathamesh Pai, Anil D'Cruz, Pankaj Chaturvedi, Atanu Bhattacharjee, Kumar Prabhash
INTRODUCTION: Sinonasal tumors are chemotherapy responsive which frequently present in advanced stages making NACT a promising option for improving resection and local control in borderline resectable and locally advanced tumours. Here we reviewed the results of 25 such cases treated with NACT. MATERIALS AND METHODS: Sinonasal tumor patients treated with NACT were selected for this analysis. These patients received NACT with platinum and etoposide for 2 cycles. Patients who responded and were amenable for gross total resection underwent surgical resection and adjuvant CTRT...
2016: International Journal of Surgical Oncology
https://www.readbyqxmd.com/read/26425367/influence-of-individual-surgeon-volume-on-oncological-outcome-of-colorectal-cancer-surgery
#20
Marleen Buurma, Hidde M Kroon, Marlies S Reimers, Peter A Neijenhuis
BACKGROUND: Surgery performed by a high-volume surgeon improves short-term outcomes. However, not much is known about long-term effects. Therefore we performed the current study to evaluate the impact of high-volume colorectal surgeons on survival. METHODS: We conducted a retrospective analysis of our prospectively collected colorectal cancer database between 2004 and 2011. Patients were divided into two groups: operated on by a high-volume surgeon (>25 cases/year) or by a low-volume surgeon (<25 cases/year)...
2015: International Journal of Surgical Oncology
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