Y Mohammed Tausif, Dithu Thekkekkara, Thummuru Ekshita Sai, Vaishnavi Jahagirdar, H R Arjun, S K Meheronnisha, Amrita Babu, Aniruddha Banerjee
Heat-shock proteins (HSPs), also known as stress proteins, are ubiquitously present in all forms of life. They play pivotal roles in protein folding and unfolding, the formation of multiprotein complexes, the transportation and sorting of proteins into their designated subcellular compartments, the regulation of the cell cycle, and signalling processes. These HSPs encompass HSP27, HSP40, HSP70, HSP60, and HSP90, each contributing to various cellular functions. In the context of cancer, HSPs exert influence by either inhibiting or activating diverse signalling pathways, thereby impacting growth, differentiation, and cell division...
April 2024: 3 Biotech