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Chonnam Medical Journal

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https://www.readbyqxmd.com/read/29854680/congenital-absence-of-the-left-atrial-appendage-an-unexpected-and-incidental-anomaly-in-a-patient-with-multiple-cerebellar-infarctions
#1
Doohyuck Lee, Dongmin Kim
No abstract text is available yet for this article.
May 2018: Chonnam Medical Journal
https://www.readbyqxmd.com/read/29854679/spontaneous-huge-subdural-spine-hematoma-in-a-patient-receiving-dual-anti-platelet-therapy-after-drug-eluting-coronary-stent-implantation
#2
Xiongyi Han, Jumin Won, Doo Sun Sim, Min Chul Kim, Yongcheol Kim, Young Joon Hong, Ju Han Kim, Youngkeun Ahn, Myung Ho Jeong
No abstract text is available yet for this article.
May 2018: Chonnam Medical Journal
https://www.readbyqxmd.com/read/29854678/endogenous-bacterial-endopthalmitis-from-long-term-use-of-a-tunneled-cuffed-hemodialysis-catheter-infection
#3
Young Rok Ham, Ki Ryang Na
No abstract text is available yet for this article.
May 2018: Chonnam Medical Journal
https://www.readbyqxmd.com/read/29854677/effects-of-bisoprolol-are-comparable-with-carvedilol-in-secondary-prevention-of-acute-myocardial-infarction-in-patients-undergoing-percutaneous-coronary-intervention
#4
Seung Jin Jun, Kyung Hwan Kim, Myung Ho Jeong, Min Chul Kim, Doo Sun Sim, Young Joon Hong, Ju Han Kim, Myeong Chan Cho, Jei Keon Chae, Hun Sik Park, Jong Sun Park, Young Keun Ahn
Although the benefits of carvedilol have been demonstrated in the era of percutaneous coronary intervention (PCI), very few studies have evaluated the efficacy of bisoprolol in the secondary prevention of acute myocardial infarction (MI) in patients treated with PCI. We hypothesized that the effect of bisoprolol would not be different from carvedilol in post-MI patients. A total of 13,813 patients who underwent PCI were treated either with carvedilol or bisoprolol at the time of discharge. They were enrolled from the Korean Acute MI Registry (KAMIR)...
May 2018: Chonnam Medical Journal
https://www.readbyqxmd.com/read/29854676/role-of-red-cell-distribution-width-in-the-relationship-between-clinical-outcomes-and-anticoagulation-response-in-patients-with-atrial-fibrillation
#5
Ki Hong Lee, Jeong Gwan Cho, Hyung Wook Park, Nam Sik Yoon, Hyung Ki Jeong, Nuri Lee
Little is known as to why elevated red cell distribution width (RDW) is associated with adverse clinical outcomes in patients with atrial fibrillation (AF). We hypothesized that RDW value might predict the intensity of anticoagulation, resulting in higher adverse events in patients with AF taking warfarin. We analyzed 657 patients with non-valuvular AF who took warfarin. The intensity of anticoagulation was assessed as mean time in the therapeutic range (TTR) and defined TTR ≥60% as an optimal intensity. The primary end-point was the composite of stroke/systemic embolism and major bleeding...
May 2018: Chonnam Medical Journal
https://www.readbyqxmd.com/read/29854675/addressing-the-side-effects-of-contemporary-antidepressant-drugs-a-comprehensive-review
#6
REVIEW
Sheng-Min Wang, Changsu Han, Won-Myoung Bahk, Soo-Jung Lee, Ashwin A Patkar, Prakash S Masand, Chi-Un Pae
Randomized trials have shown that selective serotonin reuptake inhibitors (SSRIs) and serotonin-norepinephrine reuptake inhibitors (SNRIs) have better safety profiles than classical tricyclic antidepressants (TCAs). However, an increasing number of studies, including meta-analyses, naturalistic studies, and longer-term studies suggested that SSRIs and SNRIs are no less safe than TCAs. We focused on comparing the common side effects of TCAs with those of newer generation antidepressants including SSRIs, SNRIs, mirtazapine, and bupropion...
May 2018: Chonnam Medical Journal
https://www.readbyqxmd.com/read/29854674/updates-on-cancer-epidemiology-in-korea-2018
#7
REVIEW
Sun-Seog Kweon
Cancer is a major cause of morbidity and the most common cause of death in Korea. There are currently approximately 200,000 incident cancer cases and 78,000 individuals die from cancer every year. The factors directly related to cancer incidence, including aging, smoking, obesity, and Westernized dietary habits, have been increasing during the past several decades. Since 1999, trends toward increased incidence have been observed for thyroid, breast (in women), colorectal, and prostate cancer. Currently, these trends have changed direction, and the incidence of stomach and liver cancer in both sexes, and cervical cancer in women have continually declined...
May 2018: Chonnam Medical Journal
https://www.readbyqxmd.com/read/29854673/can-tissue-cilia-lengths-and-urine-cilia-proteins-be-markers-of-kidney-diseases
#8
REVIEW
Kwon Moo Park
The primary cilium is an organelle which consists of a microtubule in the core and a surrounding cilia membrane, and has long been recognized as a "vestigial organelle". However, new evidence demonstrates that the primary cilium has a notable effect on signal transduction in the cell and is associated with some genetic and non-genetic diseases. In the kidney, the primary cilium protrudes into the Bowman's space and the tubular lumen from the apical side of epithelial cells. The length of primary cilia is dynamically altered during the normal cell cycle, being shortened by retraction into the cell body at the entry of cell division and elongated at differentiation...
May 2018: Chonnam Medical Journal
https://www.readbyqxmd.com/read/29399573/de-novo-cd5-positive-primary-gastric-diffuse-large-b-cell-lymphoma-coexpressing-myc-and-bcl6-towards-a-proper-subset-of-double-hit-triple-hit-and-maybe-quadruple-hit-b-cell-lymphomas
#9
EDITORIAL
https://www.readbyqxmd.com/read/29399572/hypophosphatemic-osteomalacia-with-multiple-bone-fractures-adv-induced-fanconi-s-syndrome
#10
Jee Hyuk Kim, Heung Yong Jin, Hong Sun Baek, Kyung Ae Lee
No abstract text is available yet for this article.
January 2018: Chonnam Medical Journal
https://www.readbyqxmd.com/read/29399571/imaging-findings-of-venous-malformation-in-neck
#11
Dong Hoon Lee, Tae Mi Yoon, Joon Kyoo Lee, Sang Chul Lim
No abstract text is available yet for this article.
January 2018: Chonnam Medical Journal
https://www.readbyqxmd.com/read/29399570/recovery-of-high-degree-atrioventricular-block-in-a-patient-with-cardiac-sarcoidosis-by-corticosteroid-therapy
#12
Hyukjin Park, Jong Chun Park, Jae Yeong Cho, Hyun Ju Yoon, Kye Hun Kim, Youngkeun Ahn, Myung Ho Jeong, Jeong Gwan Cho
No abstract text is available yet for this article.
January 2018: Chonnam Medical Journal
https://www.readbyqxmd.com/read/29399569/vocal-cord-palsy-after-left-pulmonary-artery-stent-insertion
#13
Seung Min Baek, Hyun Chung, Gi Beom Kim, Mi Kyung Song, Eun Jung Bae, Chung Il Noh
No abstract text is available yet for this article.
January 2018: Chonnam Medical Journal
https://www.readbyqxmd.com/read/29399568/effects-of-atp-on-pacemaker-activity-of-interstitial-cells-of-cajal-from-the-mouse-small-intestine
#14
Il Koo Park, Jin Ho Kim, Chan Guk Park, Man Yoo Kim, Shankar Prasad Parajuli, Chan Sik Hong, Seok Choi, Jae Yeoul Jun
Purinergic receptors play an important role in regulating gastrointestinal (GI) motility. Interstitial cells of Cajal (ICCs) are pacemaker cells that regulate GI smooth muscle activity. We studied the functional roles of external adenosine 5'-triphosphate (ATP) on pacemaker activity in cultured ICCs from mouse small intestines by using the whole-cell patch clamp technique and intracellular Ca2+ ([Ca2+ ]i ) imaging. External ATP dose-dependently depolarized the resting membrane and produced tonic inward pacemaker currents, and these effects were antagonized by suramin, a purinergic P2 receptor antagonist...
January 2018: Chonnam Medical Journal
https://www.readbyqxmd.com/read/29399567/safety-and-efficacy-of-the-endeavor-resolute%C3%A2-stent-in-patients-with-multivessel-disease-the-heart-honam-endeavor-resolute-prospective-multicenter-trial
#15
Doo Sun Sim, Myung Ho Jeong, Young Joon Hong, Ju Han Kim, Youngkeun Ahn, Keun Ho Park, Sun Ho Hwang, Dong Goo Kang, Seung Uk Lee, Joon Woo Kim, Jong Pil Park, Jay Young Rhew, Sang Rok Lee, Jei Keon Chae, Kyeong Ho Yun, Seok Kyu Oh, Won You Kang, Su Hyun Kim, Jang Hyun Cho
The Endeavor Resolute® (ER) is a zotarolimus-eluting stent (ZES) with a biocompatible BioLinx polymer. This study prospectively compared the clinical outcomes of 2 versions of ZES, ER and Endeavor Sprint® (ES), in patients with multivessel disease. A total of 488 patients who underwent multivessel percutaneous coronary intervention (PCI) were divided into 2 groups the ER group (n=288) and the ES group (n=200). The primary endpoint was a composite of major adverse cardiac events (MACE) consisting of death, myocardial infarction, and target vessel revascularization after 12 months...
January 2018: Chonnam Medical Journal
https://www.readbyqxmd.com/read/29399566/predictive-value-of-procalcitonin-for-infection-and-survival-in-adult-cardiogenic-shock-patients-treated-with-extracorporeal-membrane-oxygenation
#16
Do Wan Kim, Hwa Jin Cho, Gwan Sic Kim, Sang Yun Song, Kook Joo Na, Sang Gi Oh, Bong Suk Oh, In Seok Jeong
Procalcitonin (PCT) is a predictive marker for the occurrence of bacterial infection and the decision to terminate antibiotic treatment in critically ill patients. An unusual increase in PCT, regardless of infection, has been observed during extracorporeal membrane oxygenation (ECMO) support. We evaluated trends and the predictive value of PCT levels in adult cardiogenic shock during treatment with ECMO. We reviewed the clinical records of 38 adult cardiogenic shock patients undergoing veno-arterial ECMO support between January 2014 and December 2016...
January 2018: Chonnam Medical Journal
https://www.readbyqxmd.com/read/29399565/clinical-outcomes-of-elderly-patients-with-non-st-segment-elevation-myocardial-infarction-undergoing-coronary-artery-bypass-surgery
#17
Woo Jin Kim, Myung Ho Jeong, Dong Goo Kang, Seung Uk Lee, Sang Ki Cho, Youngkeun Ahn, Young Jo Kim, Chong Jin Kim, Myeong Chan Cho
The aim of this study is to investigate the clinical outcomes of the elderly patients with Non ST-segment elevation myocardial infarction (NSTEMI) undergoing coronary artery bypass surgery (CABG) compared to non-elderly patients. Patients with NSTEMI and undergoing CABG (n=451) who were registered in the Korea Acute Myocardial Infarction Registry between December 2003 and August 2012 were divided into two groups.; the non-elderly group (<75 years, n=327) and the elderly group (≥75 years, n=124). In-hospital mortality was higher in the elderly group (4...
January 2018: Chonnam Medical Journal
https://www.readbyqxmd.com/read/29399564/the-benefits-of-resection-for-gastric-carcinoma-patients-with-non-curative-factors
#18
Jae Hyuk Lee, Ho Gun Kim, Seong Yeob Ryu, Dong Yi Kim
The benefits of resection for gastric carcinoma patients with non-curative factors remain controversial. Thus, we evaluated the survival benefits of resection in these gastric carcinoma patients. We reviewed the hospital records of 467 gastric carcinoma patients with non-curative factors who had resection (n=305) and compared their clinicopathological findings with individuals (n=162) who underwent bypass or exploration from 1996 to 2010. The 3-year survival rate of patients who had resection was higher than was that of patients who did not (13...
January 2018: Chonnam Medical Journal
https://www.readbyqxmd.com/read/29399563/detection-of-familial-hypercholesterolemia-using-next-generation-sequencing-in-two-population-based-cohorts
#19
Hee Nam Kim, Sun-Seog Kweon, Min-Ho Shin
We aimed to evaluate the prevalence of familial hypercholesterolaemia (FH) in a subject with hypercholesterolaemia from two population-based cohorts in South Korea. A total of 283 subjects with total cholesterol levels of 290 mg/dL (7.5 mmol/L) or higher were selected from the Namwon and Dong-gu Studies. We used next generation sequencing (NGS) to detect mutations in low-density lipoprotein receptors (LDLR), apolipoprotein B (APOB) and proprotein convertase subtilisin/kexin type 9 (PCSK9) genes. We have confirmed 17 different mutations of the LDLR, APOB and PCSK9 in 23 subjects (8...
January 2018: Chonnam Medical Journal
https://www.readbyqxmd.com/read/29399562/antidiabetic-drug-metformin-protects-neuronal-cells-against-quinolinic-acid-induced-excitotoxicity-by-decreasing-intracellular-calcium
#20
Sujeong Jang, Sah-Hoon Park
The antidiabetic drug metformin has been found to have beneficial effects in various neurological disorders; however, the molecular mechanisms underlying these effects remain unclear. Here we report that metformin protects neuronal cells from quinolinic acid (QUIN)-induced excitotoxicity. For this, we pretreated N18D3 neuronal cells with metformin prior to QUIN for 24 h. We found that pretreating the cells with metformin significantly improved cell survival rate in a concentration-dependent manner and reduced apoptotic cell death, as revealed by a MTT assay and DAPI staining, respectively...
January 2018: Chonnam Medical Journal
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