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Chonnam Medical Journal

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https://www.readbyqxmd.com/read/29026716/benign-recurrent-pleomorphic-adenoma-of-the-parotid-gland-with-perineural-space-invasion
#1
EDITORIAL
Luca Roncati, Antonio Maiorana
No abstract text is available yet for this article.
September 2017: Chonnam Medical Journal
https://www.readbyqxmd.com/read/29026715/the-all-or-none-law-applied-to-the-vertical-growth-phase-of-cutaneous-malignant-melanoma
#2
EDITORIAL
Luca Roncati, Benedetto Vergari, Antonio Del Gaudio
No abstract text is available yet for this article.
September 2017: Chonnam Medical Journal
https://www.readbyqxmd.com/read/29026714/inflammatory-pseudotumor-of-the-lung-a-rare-presentation-with-complete-regression-to-pharmacotherapy
#3
Jinyung Ju
No abstract text is available yet for this article.
September 2017: Chonnam Medical Journal
https://www.readbyqxmd.com/read/29026713/vitamin-c-induced-acute-kidney-injury
#4
Eun Hui Bae, Sung Sun Kim, Seong Kwon Ma, Soo Wan Kim
No abstract text is available yet for this article.
September 2017: Chonnam Medical Journal
https://www.readbyqxmd.com/read/29026712/therapy-related-acute-myeloid-leukemia-following-treatment-for-burkitt-s-lymphoma
#5
Seung-Shin Lee
No abstract text is available yet for this article.
September 2017: Chonnam Medical Journal
https://www.readbyqxmd.com/read/29026711/glycated-hemoglobin-and-all-cause-mortality-in-korean-type-2-diabetes
#6
Mi Suk An, Sun A Kim, Jun-Ho Lee, Seong-Woo Choi, Min-Ho Shin
The purpose of this study was to evaluate the association between glycated hemoglobin (HbA1c) and all-cause mortality in type 2 diabetes mellitus. We conducted a community-based prospective cohort study of 352 type 2 diabetic patients aged 30-92 who participated in a community diabetes complications screening program in Gokseng-gun, Jeollanamdo, Korea. HbA1c levels were categorized as <6.5%, 6.5-6.9%, 7.0-7.9%, 8.0-8.9% and ≥9.0%. Patients were followed up on for a mean of 6.9 years. The Cox proportional hazards model was used to evaluate the relationship between HbA1c levels and all-cause mortality...
September 2017: Chonnam Medical Journal
https://www.readbyqxmd.com/read/29026710/factors-associated-with-c-peptide-levels-after-diagnosis-in-children-with-type-1-diabetes-mellitus
#7
Jung Won Hwang, Min Sun Kim, Dae-Yeol Lee
C-peptide is the best indicator of endogenous insulin secretion in patients with diabetes. This study investigated the relationship between C-peptide levels and clinical/laboratory parameters of children with type 1 diabetes mellitus (T1DM), as measured at 6-month intervals after diagnosis. We retrospectively reviewed the data of 34 children with newly diagnosed T1DM. The study subjects were subdivided into a rapid progression group with C-peptide levels <0.6 ng/mL at 36 months (n=27; Group A) and a slow progression group with C-peptide levels >0...
September 2017: Chonnam Medical Journal
https://www.readbyqxmd.com/read/29026709/needle-aspiration-biopsy-of-seminiferous-tubules-nabst-as-a-diagnostic-method-in-korea
#8
Jay Ho Jung, Tae Ho Lee, Kyung Hwa Choi, Jae Yup Hong
To evaluate the diagnostic efficacy of needle aspiration biopsy of seminiferous tubules (NABST) and to represent the redistributed diagnostic results corresponding to testicular volumes and follicle-stimulating hormone (FSH) levels. In this retrospective study, we investigated 65 infertile men with either azoospermia or oligoasthenoteratozoospermia. Following NABST, specimens were stained with hematoxylin and eosin and classified into five histological types. With pre-procedure FSH levels and testicular volumes, we evaluated the probabilities of detecting sperms within biopsy specimens...
September 2017: Chonnam Medical Journal
https://www.readbyqxmd.com/read/29026708/identification-of-risk-factors-influencing-in-stent-restenosis-with-acute-coronary-syndrome-presentation
#9
Jae Young Cho
Although the angiographic rates of in-stent restenosis (ISR) at later months have reduced dramatically with the introduction of drug-eluting stents (DESs), some patients with ISR after implantation of DES present with acute coronary syndrome (ACS). Here, we sought to identify parameters influencing the likelihood of restenosis with ACS presentation after DES implantation. Stented patients (n=3,817) with DESs in the Korea University Anam Hospital percutaneous coronary intervention registry were reviewed retrospectively for inclusion...
September 2017: Chonnam Medical Journal
https://www.readbyqxmd.com/read/29026707/nadph-oxidase-mediates-%C3%AE-amyloid-peptide-induced-neuronal-death-in-mouse-cortical-cultures
#10
Kee-Oh Chay, Kyoung Young Nam Koong, Shinae Hwang, Jong-Keun Kim, Choon Sang Bae
β-Amyloid peptide (Aβ) is the main component of senile plaques in patients with Alzheimer's disease, and is known to be a main pathogenic factor of the disease. Recent evidence indicates that activation of NADPH oxidase (NOX) in microglia or astrocytes may be a source of Aβ-induced reactive oxygen species (ROS). We investigated the role of neuronal NOX in Aβ-induced neuronal death in mouse mixed cortical cultures. Cell death was assessed by measuring lactate dehydrogenase efflux to bathing media 24 or 48 hr after exposure to Aβ25-35, a fragment of Aβ with an equivalent neurotoxic effect...
September 2017: Chonnam Medical Journal
https://www.readbyqxmd.com/read/29026706/development-of-novel-drug-eluting-stents-for-acute-myocardial-infarction
#11
REVIEW
Doo Sun Sim, Myung Ho Jeong
Delayed arterial healing at culprit sites after drug-eluting stent (DES) placement for acute myocardial infarction (AMI) is associated with increased risk of late stent thrombosis. The Korea Acute Myocardial Infarction Registry was established in commemoration of the 50(th) anniversary of Korea Circulation Society. Between November 2005 and December 2016, more than 62,000 patients were registered from 50 primary percutaneous coronary intervention (PCI) centers in Korea. DES in AMI may be safe and effective, however, there is concern about increased stent thrombosis after DES implantation in AMI patients, requiring longer-term dual anti-platelet therapy to reduce the risk of late stent thrombosis...
September 2017: Chonnam Medical Journal
https://www.readbyqxmd.com/read/29026705/role-of-recepteur-d-origine-nantais-on-gastric-cancer-development-and-progression
#12
REVIEW
Sung Yeul Yang, Thi Thinh Nguyen, Trong Thuan Ung, Young Do Jung
Recepteur d'origine nantais (RON) is a receptor tyrosine kinase belonging to the subfamily of which c-MET is the prototype. Large epidemiologic studies have confirmed the strong association between RON and gastric cancer development. Constitutive activation of RON signaling directly correlates with tumorigenic phenotypes of gastric cancer and a poor survival rate in advanced gastric cancer patients. In this review, we focus on recent evidence of the aberrant expression and activation of RON in gastric cancer tumors and provide insights into the mechanism of RON signaling associated with gastric cancer progression and metastasis...
September 2017: Chonnam Medical Journal
https://www.readbyqxmd.com/read/29026704/therapeutic-inhibitors-against-mutated-braf-and-mek-for-the-treatment-of-metastatic-melanoma
#13
REVIEW
Sunhyo Ryu, Chakyung Youn, Ae Ran Moon, Amanda Howland, Cheryl A Armstrong, Peter I Song
Melanoma is one of the most aggressive cancers in the world and is responsible for the majority of skin cancer deaths. Recent advances in the field of immunotherapy using active, adoptive, and antigen-specific therapeutic approaches, have generated the expectation that these technologies have the potential to improve the treatment of advanced malignancies, including melanoma. Treatment options for metastatic melanoma patients have been dramatically improved by the FDA approval of new therapeutic agents including vemurafenib, dabrafenib, and sorafenib...
September 2017: Chonnam Medical Journal
https://www.readbyqxmd.com/read/28584799/transcatheter-occlusion-of-a-giant-pulmonary-arteriovenous-malformation-in-a-1-year-old-child-using-amplatzer-vascular-plugs-and-interlocking-detachable-coils
#14
https://www.readbyqxmd.com/read/28584798/bile-cast-nephropathy-associated-with-acute-hepatitis-a
#15
Jong Hwan Jung
No abstract text is available yet for this article.
May 2017: Chonnam Medical Journal
https://www.readbyqxmd.com/read/28584797/panax-ginseng-induces-toxic-hepatitis-and-acute-kidney-injury
#16
Jeong Ho Lee, Jung Hwan Yoon, Sung Sun Kim, Seong Kwon Ma, Soo Wan Kim, Eun Hui Bae
No abstract text is available yet for this article.
May 2017: Chonnam Medical Journal
https://www.readbyqxmd.com/read/28584796/microrna-29-family-suppresses-the-invasion-of-ht1080-human-fibrosarcoma-cells-by-regulating-matrix-metalloproteinase-2-expression
#17
Jin Hee Kim, Songhee Jeon, Boo Ahn Shin
Matrix metalloproteinase 2 (MMP2) is a potent protumorigenic, proangiogenic, and prometastatic enzyme that is overexpressed in metastatic cancer. Although there have been various studies on the MMP2 gene, further studies of regulatory factors are required to achieve inhibition of MMP2 enzyme activities. MicroRNAs (miRNAs) play key roles in tumor metastasis. However, the specific functions of miRNAs in metastasis are unclear. In this study, we assessed the function of the microRNA-29 family (miR-29s) in HT1080 human fibrosarcoma cells and examined the regulatory mechanisms of these miRNAs on MMP2 activation...
May 2017: Chonnam Medical Journal
https://www.readbyqxmd.com/read/28584795/carotid-atherosclerosis-and-electrocardiographic-left-ventricular-hypertrophy-in-the-general-population-the-namwon-study
#18
Nam-Ho Kim, Min-Ho Shin, Sun-Seog Kweon, Jum Suk Ko, Young-Hoon Lee
This study aimed to investigate the relationship between carotid atherosclerosis and left ventricular hypertrophy on electrocardiogram (ECG-LVH) on adults living in the community. A total of 9,266 adults who participated in the Namwon Study were included in this analysis. Carotid atherosclerosis, including intima-media thickness (IMT) and plaques, were assessed using high-resolution B-mode ultrasound. ECG-LVH was determined using the Sokolow-Lyon voltage (SokV) and Cornell voltage (CorV) criteria. The prevalence of ECG-LVH was 12...
May 2017: Chonnam Medical Journal
https://www.readbyqxmd.com/read/28584794/correlations-between-high-platelet-reactivity-extent-of-coronary-artery-disease-and-periprocedural-myonecrosis-in-patients-with-acute-coronary-syndrome
#19
Kyeong Ho Yun, Jum Suk Ko, Jeong Mi Lee, Sang Jae Rhee
The purpose of the present study was to evaluate the correlations between high platelet reactivity (HPR) and the extent of coronary atherosclerosis and periprocedural myonecrosis in patients with acute coronary syndrome (ACS) who underwent percutaneous coronary intervention (PCI). A total of 485 patients who underwent PCI for ACS was studied. HPR was defined as ≥230 platelet reactivity units (PRU) in point-of-care P2Y12 tested by the VerifyNow assay. The incidence of multi-vessel disease (MVD) was higher in patients with HPR than those with no HPR (56...
May 2017: Chonnam Medical Journal
https://www.readbyqxmd.com/read/28584793/clinical-significance-of-p53-protein-expression-beta-catenin-expression-and-her2-expression-for-epstein-barr-virus-associated-gastric-cancer
#20
Dong Won Baek, Byung Woog Kang, Soyoon Hwang, Jong Gwang Kim, An Na Seo, Han Ik Bae, Oh Kyoung Kwon, Seung Soo Lee, Ho Young Chung, Wansik Yu
This study assessed the expression of the p53 protein, beta-catenin, and HER2 and their prognostic implications in patients with EBV-associated gastric cancer (EBVaGC). After reviewing 1318 consecutive cases of surgically resected or endoscopic submucosal dissected gastric cancers, 117 patients were identified as EBV-positive using EBV-encoded RNA in-situ hybridization. The immunohistochemistry results were interpreted as follows: strong p53 nuclear expression in at least 50% of tumor nuclei was interpreted as a positive result, strong beta-catenin expression in at least 10% of cytoplasmic nuclei was interpreted as a positive result, and moderate or strong complete or basolateral membrane staining in 10% of tumor cells was interpreted as a positive result for HER2...
May 2017: Chonnam Medical Journal
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