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Chonnam Medical Journal

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https://www.readbyqxmd.com/read/28184344/a-case-of-acute-tubulointerstitial-nephritis-associated-with-rifampin-therapy-presenting-as-fanconi-like-syndrome
#1
Jun Tae Park, Sik Lee, Won Kim, Sung Kwang Park, Kyung Pyo Kang
No abstract text is available yet for this article.
January 2017: Chonnam Medical Journal
https://www.readbyqxmd.com/read/28184343/clinical-application-of-the-unifying-concept-of-cutaneous-melanoma
#2
EDITORIAL
Luca Roncati, Francesco Piscioli, Teresa Pusiol
No abstract text is available yet for this article.
January 2017: Chonnam Medical Journal
https://www.readbyqxmd.com/read/28184342/association-between-serum-25-hydroxyvitamin-d-levels-and-type-2-diabetes-in-korean-adults
#3
Hyun Nam, Hye-Yeon Kim, Jin-Su Choi, Sun-Seog Kweon, Young-Hoon Lee, Hae-Sung Nam, Kyeong-Soo Park, So-Yeon Ryu, Seong-Woo Choi, Su-Hyun Oh, Sun A Kim, Min-Ho Shin
Previous studies have suggested that a vitamin D deficiency increases the risk of type 2 diabetes. This study evaluated the association between serum vitamin D levels and type 2 diabetes in Korean adults. This study included 9,014 subjects (3,600 males and 5,414 females) aged ≥50 years who participated in the Dong-gu Study. The subjects were divided into groups in whom the serum vitamin D level was severely deficient (<10 ng/mL), deficient (10 to <20 ng/mL), insufficient (20 to <30 ng/mL) and sufficient (≥30 ng/mL)...
January 2017: Chonnam Medical Journal
https://www.readbyqxmd.com/read/28184341/supraclavicular-lymph-node-excision-biopsy-in-patients-with-suspected-supraclavicular-lymph-node-metastasis-of-lung-cancer-experience-in-a-tertiary-hospital
#4
Dong Hoon Lee, Tae Mi Yoon, Joon Kyoo Lee, Sang Chul Lim
The aim of this study was to evaluate the usefulness and accuracy of supraclavicular lymph node excision biopsy in the diagnosis of suspected supraclavicular lymph node metastasis of lung cancer. A retrospective review was performed to evaluate patients with suspected supraclavicular lymph node metastasis of lung cancer who underwent supraclavicular lymph node excision biopsy from January 2011 to July 2014. Forty-six patients with suspected supraclavicular lymph node metastasis of lung cancer underwent supraclavicular lymph node excision biopsy, which diagnosed benign diseases in 6 patients and malignant diseases in 40 patients...
January 2017: Chonnam Medical Journal
https://www.readbyqxmd.com/read/28184340/biomarkers-predicting-survival-of-sepsis-patients-treated-with-continuous-renal-replacement-therapy
#5
Jeong Ho Lee, Ha Yeon Kim, Eun Hui Bae, Soo Wan Kim, Seong Kwon Ma
The present study investigated the prognostic factors predicting survival of patients with sepsis and acute kidney injury (AKI) undergoing continuous renal replacement therapy (CRRT). This retrospective observational study included 165 sepsis patients treated with CRRT. The patients were divided into two groups; the survivor group (n=73, 44.2%) vs. the nonsurvivor group (n=92, 55.8%). AKI was defined by the 2012 Kidney Disease: Improving Global Outcomes Clinical Practice Guidelines. We analyzed medical histories, clinical characteristics and laboratory findings of the enrolled patients when they started CRRT...
January 2017: Chonnam Medical Journal
https://www.readbyqxmd.com/read/28184339/correlation-between-infective-factors-and-antibiotic-resistance-in-enterococci-clinical-isolates-in-west-of-iran
#6
Mohammad Reza Arabestani, Mona Nasaj, Seyed Masoud Mousavi
The present study was done to scrutinize the possible relation between infective genes and antimicrobial resistance in Enterococcus faecalis and Enterococcus faecium. Considering the fact that the presence of recognized infective determinants among clinical isolates may promote the emergence of infections and persistence of Enterococci in hospital settings, which can lead to an increase in antimicrobial resistance. 175 E. faecalis and 67 E. faecium isolated from clinical specimens were used. The isolates were identified, and then antibiotic susceptibility testing was performed...
January 2017: Chonnam Medical Journal
https://www.readbyqxmd.com/read/28184338/the-clinical-importance-of-perforator-preservation-in-intracranial-aneurysm-surgery-an-overview-with-a-review-of-the-literature
#7
REVIEW
Sung-Pil Joo, Tae-Sun Kim
Clipping for intracranial aneurysms is done to achieve complete occlusion of the aneurysm without a remnant sac. Despite modern advancements of neurosurgical techniques, morbidity related to the clipping of intracranial aneurysms still exists. Clip occlusion of a parent artery or small hidden perforators commonly leads to permanent neurological deficits, and is a serious and unwanted complication. Thus, preserving blood flow in the branches and perforators of a parent artery is very important for successful surgery without postoperative morbidity and mortality...
January 2017: Chonnam Medical Journal
https://www.readbyqxmd.com/read/28184337/atoh1-as-a-coordinator-of-sensory-hair-cell-development-and-regeneration-in-the-cochlea
#8
Sungsu Lee, Han-Seong Jeong, Hyong-Ho Cho
Cochlear sensory hair cells (HCs) are crucial for hearing as mechanoreceptors of the auditory systems. Clarification of transcriptional regulation for the cochlear sensory HC development is crucial for the improvement of cell replacement therapies for hearing loss. Transcription factor Atoh1 is the key player during HC development and regeneration. In this review, we will focus on Atoh1 and its related signaling pathways (Notch, fibroblast growth factor, and Wnt/β-catenin signaling) involved in the development of cochlear sensory HCs...
January 2017: Chonnam Medical Journal
https://www.readbyqxmd.com/read/28184336/versatile-functions-of-caveolin-1-in-aging-related-diseases
#9
REVIEW
Kim Cuc Thi Nguyen, Kyung A Cho
Caveolin-1 (Cav-1) is a trans-membrane protein that is a major component of the caveolae structure on the plasma membrane. Cav-1 is involved in the regulation of various cellular processes, including cell growth, differentiation, endocytosis, and in particular it has been implied in cellular senescence. Here we review current knowledge about Cav-1 in cellular signaling and discuss the role of Cav-1 in aging-related diseases.
January 2017: Chonnam Medical Journal
https://www.readbyqxmd.com/read/28184335/drug-and-gene-eluting-stents-for-preventing-coronary-restenosis
#10
REVIEW
Kamali Manickavasagam Lekshmi, Hui-Lian Che, Chong-Su Cho, In-Kyu Park
Coronary artery disease (CAD) has been reported to be a major cause of death worldwide. Current treatment methods include atherectomy, coronary angioplasty (as a percutaneous coronary intervention), and coronary artery bypass. Among them, the insertion of stents into the coronary artery is one of the commonly used methods for CAD, although the formation of in-stent restenosis (ISR) is a major drawback, demanding improvement in stent technology. Stents can be improved using the delivery of DNA, siRNA, and miRNA rather than anti-inflammatory/anti-thrombotic drugs...
January 2017: Chonnam Medical Journal
https://www.readbyqxmd.com/read/28184334/mixed-states-in-bipolar-disorder-etiology-pathogenesis-and-treatment
#11
REVIEW
Ather Muneer
Many bipolar disorder patients exhibit mixed affective states, which portend a generally more severe illness course and treatment resistance. In the previous renditions of Diagnostic and Statistical Manual mixed states were narrowly defined in the context of bipolar I disorder, but with the advent of DSM-5 the term "mixed episode" was dropped and replaced by "mixed features" specifier which could be broadly applied to manic, hypomanic and depressive episodes in both the bipolar spectrum and major depressive disorders...
January 2017: Chonnam Medical Journal
https://www.readbyqxmd.com/read/27689034/a-case-of-acute-pyelonephritis-in-bilateral-renal-malrotation
#12
Ha Yeon Kim, Seung Jin Lee, Eun Hui Bae, Seong Kwon Ma, Soo Wan Kim
No abstract text is available yet for this article.
September 2016: Chonnam Medical Journal
https://www.readbyqxmd.com/read/27689033/extreme-metabolic-alkalosis-caused-by-gastrostomy-tube-malposition-treated-using-conventional-hemodialysis
#13
Eun Hui Bae, Seong Kwon Ma, Soo Wan Kim
No abstract text is available yet for this article.
September 2016: Chonnam Medical Journal
https://www.readbyqxmd.com/read/27689032/association-between-vitamin-d-status-and-risk-of-peripheral-arterial-disease-the-dong-gu-study
#14
Su-Hyun Oh, Sun-Seog Kweon, Jin-Su Choi, Jung-Ae Rhee, Young-Hoon Lee, Hae-Sung Nam, Seul-Ki Jeong, Kyeong-Soo Park, So-Yeon Ryu, Seong-Woo Choi, Min-Ho Shin
Low levels of vitamin D have been associated with increased cardiovascular disease risk. However, few studies have evaluated the association between vitamin D status and peripheral arterial disease (PAD). We therefore aimed to investigate whether low 25-hydroxyvitamin D (25(OH)D) levels were associated with increased risk of PAD in the Korean population. This cross-sectional study was conducted among 8,960 subjects aged 50 years or older without known myocardial infarction or stroke. PAD was defined by an ankle brachial blood pressure index <0...
September 2016: Chonnam Medical Journal
https://www.readbyqxmd.com/read/27689031/diagnosis-and-management-of-pediatric-and-adolescent-varicocele-a-survey-of-pediatric-urologists-in-korea
#15
Tae Ho Lee, Jay Ho Jung, Young Kwon Hong
The aim of this study was to evaluate current practice patterns on diagnosis and management of pediatric varicoceles. Questionnaires of approaches to diagnosis and management of pediatric varicoceles were sent electronically to pediatric urologists. Of the 70 questionnaires e-mailed, 37 (53%) responded to the survey. 10 respondents (27%) chose to operate on varicoceles, whereas 9 (24%) chose to observe, and 18 (49%) chose to decide upon treatment depending on the clinical situation. The most important indication for varicocelectomy was a decrease in ipsilateral testicular size (n=29, 78%) followed by testicular or scrotal pain (n=4, 11%) and varicocele grade (n=4, 11%)...
September 2016: Chonnam Medical Journal
https://www.readbyqxmd.com/read/27689030/peroxisome-proliferator-activated-receptor-%C3%AE-gene-expression-and-its-association-with-oxidative-stress-in-patients-with-metabolic-syndrome
#16
Mehdi Hatami, Massoud Saidijam, Reza Yadegarzari, Shiva Borzuei, Alireza Soltanian, Marzieh Safi Arian, Mohammad Taghi Goodarzi
Regulation of the peroxisome proliferator-activated receptor-γ (PPAR-γ) gene plays an important role in controlling the metabolism of lipids and inflammatory processes. Therefore, it can be associated with the pathogenesis of metabolic syndrome (MetS). The purpose of this study was to determine the expression of this gene in peripheral blood mononuclear cells (PBMC) in patients with metabolic syndrome. Using real-time polymerase chain reaction (PCR), mRNA expression of PPAR-γ was found in PBMC from 37 subjects with MetS and 30 healthy controls...
September 2016: Chonnam Medical Journal
https://www.readbyqxmd.com/read/27689029/clinical-usefulness-of-spectral-domain-optical-coherence-tomography-in-glaucoma-and-naion
#17
REVIEW
Tae Hee Lee, Hwan Heo, Sang Woo Park
The development of optical coherence tomography (OCT) has changed the clinical management of ophthalmic diseases by furthering the understanding of pathogenesis, as well as improving the monitoring of their progression and assisting in quantifying the response to treatment modalities in ophthalmic diseases. Initially, the two-dimensional configuration of the optic nerve head (ONH) and the thickness of the retinal nerve fiber layer (RNFL) were the main OCT structural parameters used in clinical management of optic nerve diseases...
September 2016: Chonnam Medical Journal
https://www.readbyqxmd.com/read/27689028/cutaneous-melanoma-in-asians
#18
REVIEW
Sang Yub Kim, Sook Jung Yun
Malignant melanoma is a rare disease in Asians but potentially the most aggressive form of skin cancer worldwide. It can occur in any melanocyte-containing anatomic site. Four main cutaneous melanoma subtypes are recognized: lentigo maligna melanoma, superficial spreading melanoma, acral lentiginous melanoma (ALM), and nodular melanoma. Generally, excessive exposure to ultraviolet (UV) radiation increases the risk of melanoma. The exception is ALM, which is the most common melanoma subtype in Asians and is not associated with UV radiation...
September 2016: Chonnam Medical Journal
https://www.readbyqxmd.com/read/27689027/targeted-cancer-therapy-using-engineered-salmonella-typhimurium
#19
REVIEW
Jin Hai Zheng, Jung-Joon Min
Obligate or facultative anaerobic bacteria such as Bifidobacterium, Clostridium, Salmonella, or Escherichia coli specifically colonize and proliferate inside tumor tissues and inhibit tumor growth. Among them, attenuated Salmonella typhimurium (S. typhimurium) has been widely studied in animal cancer models and Phase I clinical trials in human patients. S. typhimurium genes are easily manipulated; thus diverse attenuated strains of S. typhimurium have been designed and engineered as tumor-targeting therapeutics or drug delivery vehicles that show both an excellent safety profile and therapeutic efficacy in mouse models...
September 2016: Chonnam Medical Journal
https://www.readbyqxmd.com/read/27689026/second-generation-antipsychotics-in-the-treatment-of-major-depressive-disorder-an-update
#20
REVIEW
Sheng-Min Wang, Changsu Han, Soo-Jung Lee, Tae-Youn Jun, Ashwin A Patkar, Prakash S Masand, Chi-Un Pae
Less than one third of patients who suffer from major depressive disorder (MDD) report remission following antidepressant treatments requiring more diverse treatment approaches. Augmentation of second generation antipsychotics (SGAs) has been increasingly recognized as an important treatment option. The authors have previously provided a comprehensive review of SGAs for the treatment of MDD in 2013. Since then, numerous additional clinical trials have been conducted to investigate diverse issues regarding the utility of SGAs in MDD...
September 2016: Chonnam Medical Journal
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