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European Journal of Preventive Cardiology

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https://www.readbyqxmd.com/read/29708037/thoracic-endovascular-aortic-repair-to-treat-uncomplicated-stanford-type-b-aortic-dissection-the-surgeon-s-dilemma-to-preventing-future-complications
#1
Piergiorgio Tozzi
Uncomplicated type B aortic dissections have traditionally been managed non-operatively with aggressive blood pressure control. However, the best medical treatment is associated with a considerable risk of disease progression to complicated dissection or aneurysmal degeneration of the affected aortic segment. Thoracic endovascular aortic repair could prevent long-term complications but, because the dissected aorta is vulnerable, it is a high-risk procedure performed in asymptomatic patient. Therefore, endovascular treatment is not a solution for all patients and it should be performed only in the subgroup prone to developing progression of the disease and future complications...
June 2018: European Journal of Preventive Cardiology
https://www.readbyqxmd.com/read/29708036/studies-on-sporadic-non-syndromic-thoracic-aortic-aneurysms-ii-alterations-of-extra-cellular-matrix-components-and-focal-adhesion-proteins
#2
Anna Chiarini, Francesco Onorati, Maddalena Marconi, Alessandra Pasquali, Cristina Patuzzo, Anna Malashicheva, Olga Irtyega, Giuseppe Faggian, Pier F Pignatti, Elisabetta Trabetti, Ubaldo Armato, Ilaria Dal Pra
Background Sporadic non-syndromic thoracic aortic aneurysms (SNSTAAs) are less well understood than familial non-syndromic or syndromic ones. Here, we focused on morphologic and molecular changes of the extracellular matrix of the tunica media of SNSTAAs. Design Single centre design. Methods Surgical media samples from seven SNSTAAs and seven controls underwent quantitative polymerase chain reaction, proteomics-bioinformatics, immunoblotting, histology and immunohistochemistry analysis. Results A down-regulation of Decorin mRNA with unchanged protein levels associated with a remarkable increase of collagen fibres...
June 2018: European Journal of Preventive Cardiology
https://www.readbyqxmd.com/read/29708035/gender-differences-in-outcomes-after-aortic-aneurysm-surgery-should-foster-further-research-to-improve-screening-and-prevention-programmes
#3
Francesco Nicolini, Antonella Vezzani, Francesco Corradi, Riccardo Gherli, Filippo Benassi, Tullio Manca, Tiziano Gherli
Background Gender-related biases in outcomes after thoracic aortic surgery are an important factor to consider in the prevention of potential complications related to aortic diseases and in the analysis of surgical results. Methods The aim of this study is to provide an up-to-date review of gender-related differences in the epidemiology, specific risk factors, outcome, and screening and prevention programmes in aortic aneurysms. Results Female patients affected by aortic disease still have worse outcomes and higher early and late mortality than men...
June 2018: European Journal of Preventive Cardiology
https://www.readbyqxmd.com/read/29708034/aortic-centres-should-represent-the-standard-of-care-for-acute-aortic-syndrome
#4
Giovanni Mariscalco, Daniele Maselli, Marco Zanobini, Aamer Ahmed, Vito D Bruno, Umberto Benedetto, Riccardo Gherli, Tiziano Gherli, Francesco Nicolini
Background Existing evidence suggests that patients affected by acute aortic syndromes (AAS) may benefit from treatment at dedicated specialized aortic centres. The purpose of the present study was to perform a meta-analysis to evaluate the impact aortic service configuration has in clinical outcomes in AAS patients. Methods The design was a quantitative and qualitative review of observational studies. We searched PubMed/ MEDLINE, EMBASE, and Cochrane Library from inception to the end of December 2017 to identify eligible articles...
June 2018: European Journal of Preventive Cardiology
https://www.readbyqxmd.com/read/29708033/the-role-of-genetic-testing-in-the-prevention-of-acute-aortic-dissection
#5
Davide Carino, Andrea Agostinelli, Alberto Molardi, Filippo Benassi, Tiziano Gherli, Francesco Nicolini
Although much has been learned about disease of the thoracic aorta, most diagnosis of thoracic aortic aneurysm (TAA) is still incidental. The importance of the genetic aspects in thoracic aortic disease is overwhelming, and today different mutations which cause TAA or alter its natural history have been discovered. Technological advance has made available testing which detects genetic mutations linked to TAA. This article analyses the genetic aspects of TAA and describes the possible role of genetic tests in the clinical setting in preventing devastating complications of TAA...
June 2018: European Journal of Preventive Cardiology
https://www.readbyqxmd.com/read/29708032/studies-on-sporadic-non-syndromic-thoracic-aortic-aneurysms-1-deregulation-of-jagged-notch-1-homeostasis-and-selection-of-synthetic-secretor-phenotype-smooth-muscle-cells
#6
Anna Chiarini, Francesco Onorati, Maddalena Marconi, Alessandra Pasquali, Cristina Patuzzo, Anna Malashichev, Olga Irtyega, Giuseppe Faggian, Pier F Pignatti, Elisabetta Trabetti, Ubaldo Armato, Ilaria Dal Pra
Background Sporadic non-syndromic thoracic aortic aneurysms (SNSTAAs) are less well understood than familial non-syndromic or syndromic ones. The study aimed at defining the peculiar morphologic and molecular changes occurring in the media layer of SNSTAAs. Design This study was based on a single centre design. Methods Media layer samples taken from seven carefully selected SNSTAAs and seven reference patients (controls) were investigated via quantitative polymerase chain reaction, proteomics-bioinformatics, immunoblotting, quantitative histology, and immunohistochemistry/immunofluorescence...
June 2018: European Journal of Preventive Cardiology
https://www.readbyqxmd.com/read/29708031/the-use-of-remowell-oxygenator-integrated-device-in-the-prevention-of-the-complications-related-to-aortic-valve-surgery-in-the-elderly-patient-preliminary-results
#7
Alberto Molardi, Maria V Di Chicco, Davide Carino, Matteo Goldoni, Matteo Ricci, Bruno Borrello, Florida Gripshi, Tiziano Gherli, Francesco Nicolini
Background The effects of fat microembolization due to cardiopulmonary bypass are well known in cardiac surgery. Our aim is to evaluate the use of the RemoweLL device (Eurosets, Medolla, Italy) during elective aortic valve replacement in elderly patients (>70 years old) to rate its biochemical and clinical effects. The RemoweLL device is an oxygenator-integrated reservoir which combines two strategies for fat emboli and leucocytes removal: filtration and supernatant elimination. Methods Forty-four elderly patients were enrolled and assigned randomly to a Group A (standard device) and a Group B (RemoweLL)...
June 2018: European Journal of Preventive Cardiology
https://www.readbyqxmd.com/read/29741419/editor-s-presentation
#8
Massimo F Piepoli
No abstract text is available yet for this article.
May 2018: European Journal of Preventive Cardiology
https://www.readbyqxmd.com/read/29701535/editor-s-presentation
#9
Massimo F Piepoli
No abstract text is available yet for this article.
May 2018: European Journal of Preventive Cardiology
https://www.readbyqxmd.com/read/29553289/long-term-effect-of-exercise-training-in-patients-after-transcatheter-aortic-valve-implantation-follow-up-of-the-sport-tavi-randomised-pilot-study
#10
Axel Pressler, Leonie Förschner, Jana Hummel, Bernhard Haller, Jeffrey W Christle, Martin Halle
Background Increased exercise capacity favourably influences clinical outcomes after transcatheter aortic valve implantation. In our SPORT:TAVI randomised pilot trial, eight weeks of endurance and resistance training (training group, TG) shortly after transcatheter aortic valve implantation resulted in significantly improved exercise capacity, muscular strength and quality of life compared to usual care (UC). However, the long-term clinical benefits of such an intervention are unknown. Design A randomised controlled trial...
May 2018: European Journal of Preventive Cardiology
https://www.readbyqxmd.com/read/29517367/validation-of-the-2016-uspstf-recommendations-for-primary-cardiovascular-prevention-in-a-large-contemporary-cohort
#11
Yochai Schonmann, Oz Bleich, Andre Matalon, Hanny Yeshua
Aims The aim of this study was to evaluate the performance of the US Preventive Services Task Force (USPSTF) cholesterol recommendations in a contemporary non-US cohort. Methods and results This is a historical cohort analysis of electronic records from Israel's largest health provider. All patients in the Tel Aviv district eligible for primary cardiovascular prevention were followed between January 2005 and December 2015. Risk was estimated by the pooled cohort equations. Statin eligibility was determined by USPSTF and American College of Cardiology and American Heart Association (ACC/AHA) recommendations...
May 2018: European Journal of Preventive Cardiology
https://www.readbyqxmd.com/read/29517366/mechanisms-of-coronary-ischaemia-in-women-are-we-any-closer-to-deciphering-the-code
#12
Adam J Nelson, Ross Roberts-Thomson, Stephen J Nicholls
No abstract text is available yet for this article.
May 2018: European Journal of Preventive Cardiology
https://www.readbyqxmd.com/read/29517365/a-reference-equation-for-maximal-aerobic-power-for-treadmill-and-cycle-ergometer-exercise-testing-analysis-from-the-friend-registry
#13
Christina G de Souza E Silva, Leonard A Kaminsky, Ross Arena, Jeffrey W Christle, Claudio Gil S Araújo, Ricardo M Lima, Euan A Ashley, Jonathan Myers
Background Maximal oxygen uptake (VO2 max) is a powerful predictor of health outcomes. Valid and portable reference values are integral to interpreting measured VO2 max; however, available reference standards lack validation and are specific to exercise mode. This study was undertaken to develop and validate a single equation for normal standards for VO2 max for the treadmill or cycle ergometer in men and women. Methods Healthy individuals ( N = 10,881; 67.8% men, 20-85 years) who performed a maximal cardiopulmonary exercise test on either a treadmill or a cycle ergometer were studied...
May 2018: European Journal of Preventive Cardiology
https://www.readbyqxmd.com/read/29517276/is-promoting-six-hours-of-standing-an-appropriate-public-health-message
#14
Aviroop Biswas, Peter M Smith, David A Alter
No abstract text is available yet for this article.
May 2018: European Journal of Preventive Cardiology
https://www.readbyqxmd.com/read/29498291/the-prognostic-strength-of-gas-analysis-measurement-during-maximal-exercise-testing
#15
Luc Vanhees
No abstract text is available yet for this article.
May 2018: European Journal of Preventive Cardiology
https://www.readbyqxmd.com/read/29493281/-stand-up-for-a-healthy-lifestyle
#16
Birna Bjarnason-Wehrens, Hans-Georg Predel
No abstract text is available yet for this article.
May 2018: European Journal of Preventive Cardiology
https://www.readbyqxmd.com/read/29488810/relative-peak-exercise-oxygen-pulse-is-related-to-sudden-cardiac-death-cardiovascular-and-all-cause-mortality-in-middle-aged-men
#17
Jari A Laukkanen, Claudio Gil S Araújo, Sudhir Kurl, Hassan Khan, Sae Y Jae, Marco Guazzi, Setor K Kunutsor
Background Preliminary evidence suggests that peak exercise oxygen pulse - peak oxygen uptake/heart rate-, a variable obtained during maximal cardiopulmonary exercise testing and a surrogate of stroke volume, is a predictor of mortality. We aimed to assess the associations of peak exercise oxygen pulse with sudden cardiac death, fatal coronary heart disease and cardiovascular disease and all-cause mortality. Design A prospective study. Methods Peak exercise oxygen pulse was assessed in a maximal cycling test at baseline in 2227 middle-aged men of the Kuopio Ischaemic Heart Disease cohort study using expired gas variables and electrocardiograms...
May 2018: European Journal of Preventive Cardiology
https://www.readbyqxmd.com/read/29488809/acute-stress-disorder-and-c-reactive-protein-in-patients-with-acute-myocardial-infarction
#18
Petar M Seferović, Milika Ašanin, Arsen D Ristić
No abstract text is available yet for this article.
May 2018: European Journal of Preventive Cardiology
https://www.readbyqxmd.com/read/29486588/the-expert-vision-of-exercise-training-in-cardiovascular-disease-patients-a-routine-practical-and-reasonable-technique
#19
Ugo Corrà
No abstract text is available yet for this article.
May 2018: European Journal of Preventive Cardiology
https://www.readbyqxmd.com/read/29486587/do-clinicians-prescribe-exercise-similarly-in-patients-with-different-cardiovascular-diseases-findings-from-the-eapc-expert-working-group-survey
#20
Dominique Hansen, Gustavo Rovelo Ruiz, Patrick Doherty, Marie-Christine Iliou, Tom Vromen, Sally Hinton, Ines Frederix, Matthias Wilhelm, Jean-Paul Schmid, Ana Abreu, Marco Ambrosetti, Esteban Garcia-Porrero, Karin Coninx, Paul Dendale
Background Although disease-specific exercise guidelines for cardiovascular disease (CVD) are widely available, it remains uncertain whether these different exercise guidelines are integrated properly for patients with different CVDs. The aim of this study was to assess the inter-clinician variance in exercise prescription for patients with various CVDs and to compare these prescriptions with recommendations from the EXercise Prescription in Everyday practice and Rehabilitative Training (EXPERT) tool, a digital decision support system for integrated state-of-the-art exercise prescription in CVD...
May 2018: European Journal of Preventive Cardiology
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