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Medical Mycology Journal

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https://www.readbyqxmd.com/read/27904074/prophylactic-effect-of-lactobacillus-pentosus-strain-s-pt84-on-candida-infection-and-gastric-inflammation-in-a-murine-gastrointestinal-candidiasis-model-errata
#1
Toshihiro Maekawa, A Sanae Ishijima, Masayuki Ida, Takayuki Izumo, Yoshiko Ono, Hiroshi Shibata, Shigeru Abe
We previously showed a prophylactic effect of Lactobacillus pentosus strain S-PT84 against oral candidiasis in mice. In the present study, we evaluated the protective effect of S-PT84 against Candida infection of the gastrointestinal tract. As the first step, we used an in vitro assay to compare the inhibitory effects of several lactobacilli (S-PT84 and Lactobacillus pentosus type strain JCM1558(T), Lactobacillus gasseri type strain JCM1131(T) and Lactobacillus casei type strain JCM1134(T)) on mycelial growth of Candida albicans...
2016: Medical Mycology Journal
https://www.readbyqxmd.com/read/27904064/term-12
#2
(no author information available yet)
No abstract text is available yet for this article.
2016: Medical Mycology Journal
https://www.readbyqxmd.com/read/27904063/onychomycosis
#3
Tomotaka Sato
No abstract text is available yet for this article.
2016: Medical Mycology Journal
https://www.readbyqxmd.com/read/27904062/promising-therapies-for-fungal-infection-based-on-the-study-to-elucidate-mechanisms-to-cope-with-stress-in-candida-species
#4
Kazuyuki Hirai, Tatsuya Inukai, Hironobu Nakayama
In recent years, the incidence of fungal infections has been increasing, particularly among patients with immune systems compromised by human immunodeficiency virus infection, organ transplantation, and/or chemotherapy for cancer. Current therapies for treating systemic fungal infection have limited effectiveness and have created problems of adverse reactions and drug resistance. These issues therefore motivate us to develop novel antifungals. Elucidation of stress response mechanisms and virulence factors in pathogenic fungi is required in developing an effective antifungal strategy...
2016: Medical Mycology Journal
https://www.readbyqxmd.com/read/27904061/diagnosis-and-treatment-of-mucormycosis-in-patients-with-hematological-malignancies
#5
Yuki Asano-Mori
The risk of invasive fungal infections (IFIs) is extremely high in patients with hematological malignancies due to the prolonged and profound neutropenia and immunosuppression after chemotherapy and hematopoietic stem cell transplantation. There has been increasing interest in mucormycosis despite its relatively uncommon occurrence, because occasional breakthrough infections have been observed under anti-aspergillus prophylaxis. The aggressive nature of mucormycosis easily leads to high mortality because of delays in diagnosis and incorrect treatment decisions, which are due in part to lack of adjunctive diagnostic tools and having similar clinical and radiological features with aspergillosis...
2016: Medical Mycology Journal
https://www.readbyqxmd.com/read/27904060/causative-agents-of-aspergillosis-including-cryptic-aspergillus-species-and-a-fumigatus
#6
Takahito Toyotome
Aspergillosis is an important deep mycosis. The causative agents are Aspergillus fumigatus, Aspergillus flavus, Aspergillus niger, and Aspergillus terreus, of which A. fumigatus is the most prevalent. Cryptic Aspergillus spp., which morphologically resemble representative species of each Aspergillus section, also cause aspergillosis. Most of the cryptic species reveal different susceptibility patterns and/or different secondary metabolite profiles, also called exometabolome in this manuscript, from those representative species...
2016: Medical Mycology Journal
https://www.readbyqxmd.com/read/27904059/comparison-of-characteristics-of-two-topical-therapeutic-agents-for-onychomycosis
#7
Tsuyoshi Shimamura, Akiko Miyamae, Ami Imai, Kozue Hirayanagi, Tomoyuki Iwanaga, Nobuo Kubota, Kazutoshi Shibuya
Two topical therapeutic agents were approved in Japan from 2015 to 2016, adding new options for onychomycosis therapy in the clinical field. In order to confirm the differences of formulation properties and nail pharmacokinetics between 5% luliconazole solution and 10% efinaconazole solution, drug concentration and antifungal activity in the nail were measured after topical treatment using human nail plates. In the in vitro permeation study, concentration of each drug was measured in the transversely sliced nail after single treatment with the two topical therapeutic agents...
2016: Medical Mycology Journal
https://www.readbyqxmd.com/read/27904058/two-cases-of-chromomycosis-identified-by-molecular-phylogenetic-analysis
#8
Takayo Mitomo, Yukiko Ushigome, Tomoo Fukuda, Yoko Kano, Tetsuo Shiohara
Chromomycosis is an infection caused by dematiaceous fungi. These fungi belong to several genera with varied clinical presentations and parasitic forms. The disease is roughly classified into three types: chromoblastomycosis, black-grain mycetoma, and phaeohyphomycosis. While there are many kinds of dematiaceous fungi, the major etiologic agent is Fonsecaea pedrosoi, which to date has accounted for 90% of chromoblastomycosis cases. The genus Fonsecaea has recently been assessed via rRNA ITS sequence analysis, and species have been classified into F...
2016: Medical Mycology Journal
https://www.readbyqxmd.com/read/27904057/potential-of-ravuconazole-and-its-prodrugs-as-the-new-oraltherapeutics-for-onychomycosis
#9
Hideyo Yamaguchi
Onychomycosis is a fungal infection of the nail apparatus caused by dermatophytes, Candida and non-dermatophytic molds. It is highly prevalent in the general population worldwide and also responsible for significant morbidity and complications and does not usually cure itself. Thus, the condition needs to be treated in view of physical and psychological problems produced. Currently, oral medications using terbinafine are the most effective therapy, but it has relatively limited therapeutic success, particularly for long-term management...
2016: Medical Mycology Journal
https://www.readbyqxmd.com/read/27904056/prophylactic-effect-of-lactobacillus-pentosus-strain-s-pt84-on-candida-infection-and-gastric-inflammation-in-a-murine-gastrointestinal-candidiasis-model
#10
Toshihiro Maekawa, A Sanae Ishijima, Masayuki Ida, Takayuki Izumo, Yoshiko Ono, Hiroshi Shibata, Shigeru Abe
We previously showed a prophylactic effect of Lactobacillus pentosus strain S-PT84 against oral candidiasis in mice. In the present study, we evaluated the protective effect of S-PT84 against Candida infection of the gastrointestinal tract. As the first step, we used an in vitro assay to compare the inhibitory effects of several lactobacilli (S-PT84 and Lactobacillus pentosus type strain JCM1558(T), Lactobacillus gasseri type strain JCM1131(T) and Lactobacillus casei type strain JCM1134(T)) on mycelial growth of Candida albicans...
2016: Medical Mycology Journal
https://www.readbyqxmd.com/read/27904055/the-first-isolation-of-aspergillus-allahabadii-from-a-cormorant-with-pulmonary-aspergillosis
#11
Sue Yee Lim, Rui Kano, Kenji Ooya, Shunta Kimura, Tokuma Yanai, Atsuhiko Hasegawa, Hiroshi Kamata
In this study, we report the first isolation of Aspergillus allahabadii from a Japanese cormorant with pulmonary aspergillosis. We performed molecular identification and antifungal susceptibility testing with the E-test. A 7-month-old male cormorant died because of uric acid deposition secondary to dehydration. Whitish nodular lesions were present on the caudal thoracic air sac in the right thoracic cavity. Histopathology revealed multifocal pyogranulomatous necrotic lesions with numerous fungal hyphae in the thoracic air sac...
2016: Medical Mycology Journal
https://www.readbyqxmd.com/read/27904054/epidemiology-of-dermatophytoses-in-crete-greece
#12
Sofia Maraki, Viktoria Eirini Mavromanolaki
Dermatophytoses are among the most frequently diagnosed skin infections worldwide. However, the distribution of pathogenic species and the predominating anatomical sites of infection vary with geographical location and change over time. The aim of this study was to determine the epidemiological and aetiological factors of dermatophytoses in Crete, Greece over the last 5-year period (2011-2015) and their incidence in relation to the gender and the age of the patients. We compared our findings with those previously reported from the same area and from other parts of the world...
2016: Medical Mycology Journal
https://www.readbyqxmd.com/read/27904053/executive-summary-of-japanese-domestic-guidelines-for-management-of-deep-seated-mycosis-2014
#13
Shigeru Kohno, Kazuo Tamura, Yoshihito Niki, Koichi Izumikawa, Shinichi Oka, Kenji Ogawa, Junichi Kadota, Katsuhiko Kamei, Yoshinobu Kanda, Tetsuya Kiuchi, Kazutoshi Shibuya, Syunji Takakura, Toru Takata, Yoshio Takesue, Katsuji Teruya, Issei Tokimatsu, Takahiro Fukuda, Shigefumi Maesaki, Koichi Makimura, Hiroshige Mikamo, Kotaro Mitsutake, Yoshitsugu Miyazaki, Masaaki Mori, Akira Yasuoka, Keiko Yano, Noboru Yamanaka, Minoru Yoshida
No abstract text is available yet for this article.
2016: Medical Mycology Journal
https://www.readbyqxmd.com/read/27904052/recent-advances-in-the-diagnosis-of-pneumocystis-pneumonia
#14
Yinggai Song, Yi Ren, Xiaowen Wang, Ruoyu Li
Pneumocystis jirovecii is a prototypical opportunistic pathogen, causing an asymptomatic or mild infection in normal hosts and fulminating pneumonia (Pneumocystis pneumonia, PCP) in immunocompromised hosts. PCP is a leading cause of morbidity and mortality in immunocompromised patients such as AIDS patients. Microscopic detection of cysts and trophic forms of P. jirovecii in respiratory secretions is simple and useful but may underestimate the P. jirovecii infection. Conventional polymerase chain reaction (PCR) and nested PCR increase the sensitivity and specificity to identify PCP and provide an approach to discriminate PCP from pulmonary P...
2016: Medical Mycology Journal
https://www.readbyqxmd.com/read/27581781/term-11
#15
(no author information available yet)
No abstract text is available yet for this article.
2016: Medical Mycology Journal
https://www.readbyqxmd.com/read/27581780/candidemia-in-cancer-patients-focus-mainly-on-hematological-malignancyand-hematopoietic-stem-cell-transplantation
#16
Keiji Okinaka
Although many new antifungals have become commercially available since 2000, candidemia remains an important public health issue because of its poor prognosis. Some studies have suggested that early antifungal therapy is associated with decreased mortality; however, it is difficult to promptly diagnose candidemia because of the poor sensitivity of blood cultures. Thus, prophylaxis against Candida infection is recommended in patient groups in whom the risk of infection is high, such as allogeneic hematopoietic stem cell transplant recipients or those undergoing intensive remission-induction chemotherapy for acute leukemia...
2016: Medical Mycology Journal
https://www.readbyqxmd.com/read/27581779/mycological-education-for-dermatologists
#17
Katsutaro Nishimoto
Mycotic infections remain important in dermatological clinics. Therefore the mycological training curriculum needs to be reorganized starting from the beginning of dermatological education, including routine examination procedures, such as potassium hydroxide examination, culture of pathogenic fungi, histopathology, treatment guidelines, and the recent advances in medical mycology.Several mycological institutes will be selected and announced in the journal to provide support for mycological examinations and to publish important cases treated in clinics...
2016: Medical Mycology Journal
https://www.readbyqxmd.com/read/27581778/the-current-status-of-drug-resistant-aspergillus
#18
Masato Tashiro, Koichi Izumikawa
Aspergillus spp. are important fungi because of the high mortality associated with aspergillosis. However, we have only three classes of anti-aspergillus drugs available; and only two drugs, itraconazole (ITCZ) and voriconazole (VRCZ), are available as oral agents in Japan. If azole-resistant Aspergillus causes chronic aspergillosis, we cannot treat such patients with oral azoles on an outpatient basis. As is the case with foreign countries, we found the existence of azole-resistant Aspergillus fumigatus in clinical settings in Japan...
2016: Medical Mycology Journal
https://www.readbyqxmd.com/read/27581777/treatment-outcomes-for-malassezia-folliculitis-in-thedermatology-department-of-a-university-hospital-in-japan
#19
Chikako Suzuki, Midori Hase, Harunari Shimoyama, Yoshihiro Sei
Topical or systemic antifungal therapy was administered to patients diagnosed with Malassezia folliculitis during the 5-year period between March 2007 and October 2013. The diagnosis of Malassezia folliculitis was established on the basis of characteristic clinical features and direct microscopic findings (10 or more yeast-like fungi per follicle). Treatment consisted of topical application of 2% ketoconazole cream or 100 mg oral itraconazole based on symptom severity and patients' preferences. Treatment was given until papules flattened, and flat papules were examined to determine whether the patient's clinical condition had "improved" and the treatment had been "effective"...
2016: Medical Mycology Journal
https://www.readbyqxmd.com/read/27581776/a-case-of-tinea-corporis-due-to-trichophyton-tonsurans-that-manifested-as-impetigo
#20
Harunari Shimoyama, Chikako Nakashima, Midori Hase, Yoshihiro Sei
A 41-year-old man visited our dermatology clinic because an eruption, which was resistant to steroid ointment treatment, had appeared on his right forearm. An oval, soybean-sized erythematous infiltrated lesion with scales and crusts was located in the central part of the extensor surface of the right forearm and showed partial erosion with attached yellow crusts. The lesion had an impetigo-like appearance. Fungal elements were confirmed from the scales by KOH examination and the fungus was identified as Trichophyton tonsurans by fungal culture and molecular method...
2016: Medical Mycology Journal
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