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Medical Mycology Journal

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https://www.readbyqxmd.com/read/28855487/erratum
#1
(no author information available yet)
No abstract text is available yet for this article.
2017: Medical Mycology Journal
https://www.readbyqxmd.com/read/28855486/term-15
#2
(no author information available yet)
No abstract text is available yet for this article.
2017: Medical Mycology Journal
https://www.readbyqxmd.com/read/28855485/potential-of-next-generation-poct-in-infectious-disease-rapid-test
#3
Naoto Shimetani
Real-time test results are necessary for early diagnosis and in determining treatment orientation in medical practice. Point of Care Testing (POCT) is a testing system that provides beneficial and helpful information for diagnosis and treatment through real-time testing at the bedside. Therefore, POCT has high utility value in the field of infectious diseases as a rapid test that provides, within the consultation hours, useful information for initial treatment.Infectious disease rapid test kits are commercially available for a wide variety of prophlogistic pathogen targets, including bacterial, viral, fungal, protozoal, and other disease agents...
2017: Medical Mycology Journal
https://www.readbyqxmd.com/read/28855484/recognition-of-cryptococcus-neoformans-by-pattern-recognition-receptors-and-its-role-in-host-defense-to-this-infection
#4
Ko Sato, Kazuyoshi Kawakami
Cryptococcus neoformans is a yeast-type opportunistic fungal pathogen with a capsule structure consisting of polysaccharides, such as glucuronoxylomannan and galactoxylomannan, and infects the lungs via an air-borne route. Most healthy individuals undergo asymptomatic infection with granulomatous lesions in the lungs caused by C. neoformans. However, immunocompromised hosts with severely impaired cellular immunity, such as those with acquired immune deficiency syndrome (AIDS), often suffer from disseminated infection into the central nervous system, leading to life-threatening meningoencephalitis...
2017: Medical Mycology Journal
https://www.readbyqxmd.com/read/28855483/current-status-of-taxonomy-of-pathogenic-yeasts
#5
Takashi Sugita, Otomi Cho, Masako Takashima
Fungal taxonomy has been reconstructed on the basis of genome information, and new nomenclatural rules have been enacted from 2013. It has been proposed that Cryptococcus neoformans and Cryptococcus gattii be reclassified into two species (C. neoformans and Cryptococcus deneoformans) and five species (C. gattii, Cryptococcus bacillisporus, Cryptococcus deuterogattii, Cryptococcus tetragattii, and Cryptococcus decagattii), respectively. The genus Trichosporon has been reclassified into five genera. Trichosporon asahii, which is the causative agent of trichosporonosis, has been retained in the genus Trichosporon, while Trichosporon cutaneum has been transferred into a new genus, Cutaneotrichosporon...
2017: Medical Mycology Journal
https://www.readbyqxmd.com/read/28855482/prof-masao-ota
#6
Tomomichi Ono
Masao Ota was a Professor of Dermatology at Tokyo Imperial University. He is known to dermatologists around the world as the researcher who identified Nevus of Ota. He is also known for his research on Hansen's Disease. He was critical of the forced isolation policy and the sterilization law. He dreamt of developing chemotherapeutic measures and dedicated himself to cultivating Mycobacterium leprae. Among his accomplishments, those in the area of medical mycology are particularly remarkable. His discovery of Microsporum ferrugineum, his proposal for Trichophytia pompholyciformis, and his work on Ota-Langeron taxonomy based on the findings on fungus colonies are highly regarded and earned him the Ordre Royale de la Legion D'honneur...
2017: Medical Mycology Journal
https://www.readbyqxmd.com/read/28855481/inhibition-of-growth-of-candida-albicans-by-a-lysozyme-chitosan-conjugate-lyzox-and-its-combination-with-decanoic-acid
#7
Hiroki Kageshima, Kazumi Hayama, Miki Takahashi, Miho Abe, Tsuyoshi Yamada, Akira Saito, Shoichiro Hirano, Yoichi Murakami, Shigeru Abe
A lysozyme-chitosan conjugate preparation (LYZOX), produced from egg white lysozyme and chitosan by Maillard reaction, is a commercial product developed as a cosmetic ingredient or food additive. Effects of LYZOX on in vitro growth of Candida albicans were examined. C. albicans cells were treated with LYZOX for 3 hrs, and then washed and cultured for an additional 16 hrs in modified RPMI1640 medium. Mycelial growth of C. albicans was clearly inhibited by more than 100 μg/ml of LYZOX in a concentration-dependent manner...
2017: Medical Mycology Journal
https://www.readbyqxmd.com/read/28855480/diagnosis-and-treatment-of-mucormycosis-in-patients-withhematological-malignancies%C3%AF-translated-article%C3%AF
#8
Yuki Asano-Mori
The risk of invasive fungal infections (IFIs) is extremely high in patients with hematological malignancies due to the prolonged and profound neutropenia and immunosuppression after chemotherapy and hematopoietic stem cell transplantation. There has been increasing interest in mucormycosis despite its relatively uncommon occurrence, because occasional breakthrough infections have been observed under anti-Aspergillus prophylaxis. The aggressive nature of mucormycosis easily leads to high mortality because of delays in diagnosis and incorrect treatment decisions, which are due in part to lack of adjunctive diagnostic tools and having similar clinical and radiological features with invasive aspergillosis...
2017: Medical Mycology Journal
https://www.readbyqxmd.com/read/28855479/epidemiology-of-zygomycosis-analysis-of-national-data-from-pathological-autopsy-cases-in-japan
#9
Yuhko Suzuki, Hikaru Kume, Tomiteru Togano, Hitoshi Ohto
BACKGROUND AND METHODS: To identify recent trends in the frequency of zygomycosis in autopsy cases, we conducted epidemiological analysis every four years from 1989 to 2009 using national data reported in the "Annual of Pathological Autopsy Cases in Japan." RESULTS: 153,615 cases were autopsied, of which 6622 (4.3%) were found to have had mycosis. Among these, there were 243 cases (3.7%) of zygomycosis, which was the fourth most predominant causative agent of mycoses among the monopathogen mycoses...
2017: Medical Mycology Journal
https://www.readbyqxmd.com/read/28855478/first-isolation-of-arthroderma-fulvum-in-japan
#10
Teru Fukutomi, Rui Kano, Hiroshi Kamata
Morphology and molecular characteristics of Microsporum gypseum clinical isolates obtained from the fur of a normal rabbit (n=1) and the soil from 10 different rabbit hutches in six elementary schools (n=10) were examined. Isolates were also identified by sequence analysis of the internal transcribed spacer (ITS) region. All 11 isolates demonstrated homology with the Arthroderma fulvum ITS sequence. Furthermore, PCR analysis for the presence of mating type genes detected positivity for MAT1-1 (n=10) and MAT1-2 (n=1)...
2017: Medical Mycology Journal
https://www.readbyqxmd.com/read/28855477/the-current-status-of-feline-sporotrichosis-in-malaysia
#11
Han Hock Siew
Feline sporotrichosis has been reported in Malaysia since the 1990's. Since then, studies have revealed that clinical clade D, Sporothrix schenckii sensu stricto, of a single clonal strain is the most common cause of this disease in Malaysia. The prevalence of a single clonal strain from a clinical clade was never before reported in Asia in a specific geographical niche. This raises the possibility of a process of purifying selection and subsequent clonal proliferation. While agricultural practices may serve as the selective pressure, direct causality has yet to be established...
2017: Medical Mycology Journal
https://www.readbyqxmd.com/read/28566668/term-14
#12
(no author information available yet)
No abstract text is available yet for this article.
2017: Medical Mycology Journal
https://www.readbyqxmd.com/read/28566667/dermatophyte-antigen-kit
#13
Yuichiro Tsunemi
The dermatophyte antigen kit uses monoclonal antibodies that react with polysaccharides present in the dermatophyte cell wall to detect dermatophyte antigens in specimens based on the principle of immunochromatography. Clinical studies showed that the kit was very useful in the diagnosis of tinea unguium but not tinea pedis. The kit was therefore further developed as an in vitro diagnostic tool for tinea unguium and was approved by the Pharmaceuticals and Medical Devices Agency of Japan. The kit's extraction solution can extract antigens from nail specimens quickly and efficiently...
2017: Medical Mycology Journal
https://www.readbyqxmd.com/read/28566666/treatment-and-prevention-of-oral-candidiasis-in-elderly-patients
#14
Hideo Sakaguchi
The incidence of oral candidiasis has increased in the elderly in recent years. Although the increase of the elderly population plays a big role in this rise of oral candidiasis, the broader recognition that elderly people have higher infection rates for oral candidiasis is considered to be also an important factor. Oral candidiasis can be categorized into three types. Pseudomembranous oral candidiasis is characterized by the appearance of white moss, erythematous oral candidiasis by the eruption of erythema, and hyperplastic oral candidiasis by mucosal hyperplasia...
2017: Medical Mycology Journal
https://www.readbyqxmd.com/read/28566665/treatment-of-tinea-pedis-in-elderly-patients-using-external-preparations
#15
Michiteru Otani
Infection rate of tinea pedis is high in the elderly, wherein treatment by a dermatologist should be considered to prevent infecting their family members. About 90 percent of cases with tinea pedis is treated only using external preparations. In treating the elderly with tinea pedis using external preparation, we should take into consideration that the elderly have thinner and weaker skin compared to younger people. There are many kinds of dosage form (cream, ointments, lotion, spray, and so on) for external preparations to treat tinea pedis...
2017: Medical Mycology Journal
https://www.readbyqxmd.com/read/28566664/remarkable-works-and-cases-in-the-history-of-medical-mycology-in-japan
#16
Katsutaro Nishimoto
Several pathogenic fungi and cases related to Japanese medical mycologists were reviewed. Trichosporon inkin (as Sarcinomyces inkin) was reported as a pathogen of scrotal lesion by Oho in 1921, and Trichosporon asahii was isolated from generalized keratotic lesions in 1922 by Akagi in Japan. They were once included in Trichophyton beigelii, but then based on revision using DNA molecular technology, were returned to their original names.Microsporum ferrugineum was reported by Ota as a causative dermatophyte of tinea capitis in Japan and surrounding areas...
2017: Medical Mycology Journal
https://www.readbyqxmd.com/read/28566663/promising-therapies-for-fungal-infection-based-on-the-study-to-elucidate-mechanisms-to-cope-with-stress-in-candida-species-translated-article
#17
Kazuyuki Hirai, Tatsuya Inukai, Hironobu Nakayama
In recent years, the incidence of fungal infections has been increasing, particularly among patients with immune systems compromised by human immunodeficiency virus infection, organ transplantation, and/or chemotherapy for cancer. Current therapies for treating systemic fungal infection have limited effectiveness and have created problems of adverse reactions and drug resistance. These issues therefore motivate us to develop novel antifungals. Elucidation of stress response mechanisms and virulence factors in pathogenic fungi is required in developing an effective antifungal strategy...
2017: Medical Mycology Journal
https://www.readbyqxmd.com/read/28566662/practical-management-of-deep-cutaneous-fungal-infections
#18
Tomotaka Sato
Understanding deep cutaneous fungal infection requires not only reading many case reports and checking the typical clinical images of skin lesions, but also managing the patients properly to prevent misdiagnosis. Herein, I review my recent experiences with eight typical cases of deep cutaneous infections (including protothecosis and nocardiosis) in Japan. It is very important to do the four management processes; namely, KOH direct microscopic examination, skin biopsy, fungal culture, and microscopic examination of the histopathological specimen of PAS and Grocott staining...
2017: Medical Mycology Journal
https://www.readbyqxmd.com/read/28566661/azole-resistant-aspergillus-fumigatus-containing-a-34-bp-tandem-repeat-in-cyp51a-promoter-is-isolated-from-the-environment-in-japan
#19
Kenji Onishi, Bolu Muhammad Sarumoh, Daisuke Hagiwara, Akira Watanabe, Katsuhiko Kamei, Takahito Toyotome
Azole-resistant strains of Aspergillus fumigatus containing a tandem repeat in the cyp51A promoter and amino acid substitution(s) have been isolated in the environment worldwide; however, this type of resistant strain had never been isolated from the environment in Japan. Our previous study indicated that an azole-resistant A. fumigatus strain OKH50 containing a 34-bp tandem repeat in cyp51A promoter with L98H substitution in Cyp51A was isolated from a patient in Obihiro of Hokkaido, Japan. In this study, we collected azole-resistant Aspergillus spp...
2017: Medical Mycology Journal
https://www.readbyqxmd.com/read/28566660/a-giant-dermatophyte-abscess-caused-by-trichophyton-rubrum-in-an-immunocompromised-patient
#20
Maiko Toyoki, Midori Hase, Yusuke Hirasawa, Takashi Umeyama, Yoshitsugu Miyazaki, Rui Kano, Takashi Sugita, Masataro Hiruma, Yuzo Kodama, Shigaku Ikeda
A 73-year-old male who had been receiving immunosuppressive drugs for 15 years developed a nodule on the left buttock region. The nodule slowly grew into a 15-cm fluctuant multilocular subcutaneous cyst. Serum beta-D-glucan levels were high, and the yellow purulent fluid obtained from the cyst was positive for Trichophyton rubrum. Granuloma formation in the cyst wall and large abscesses in the central cystic area were found, and septated hyphae were observed in both tissues. The cyst was surgically removed, and followed by itraconazole treatment...
2017: Medical Mycology Journal
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