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Medical Mycology Journal

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https://www.readbyqxmd.com/read/29491343/-term-17
#1
(no author information available yet)
No abstract text is available yet for this article.
2018: Medical Mycology Journal
https://www.readbyqxmd.com/read/29491342/-reply-to-comments-on-my-article
#2
Yuichiro Tsunemi
No abstract text is available yet for this article.
2018: Medical Mycology Journal
https://www.readbyqxmd.com/read/29491341/-erratum
#3
(no author information available yet)
No abstract text is available yet for this article.
2018: Medical Mycology Journal
https://www.readbyqxmd.com/read/29491340/-inquiry-about-the-dermatopyte-test-strip
#4
Shinichi Watanabe
No abstract text is available yet for this article.
2018: Medical Mycology Journal
https://www.readbyqxmd.com/read/29491339/-histopathological-diagnosis-of-invasive-fungal-infections-in-formalin-fixed-and-paraffin-embedded-tissues-in-conjunction-with-molecular-methods
#5
COMPARATIVE STUDY
Minoru Shinozaki, Naobumi Tochigi, Sota Sadamoto, Somay Yamagata Murayama, Megumi Wakayama, Tetsuo Nemoto
The main objective of this study was to evaluate the relationship between histopathology, polymerase chain reaction (PCR), and in situ hybridization (ISH) for the identification of causative fungi in formalin-fixed and paraffin-embedded (FFPE) tissue specimens. Since pathogenic fungi in tissue specimens can be difficult to identify morphologically, PCR and ISH have been usually employed as auxiliary procedures. However, little comparison has been made on the sensitivity and specificity of PCR and ISH using FFPE specimens...
2018: Medical Mycology Journal
https://www.readbyqxmd.com/read/29491338/-national-trends-in-the-distribution-of-candida-species-causing-candidemia-in-japan-from-2003-to-2014
#6
Hiroshi Kakeya, Koichi Yamada, Yukihiro Kaneko, Katsunori Yanagihara, Kazuhiro Tateda, Shigefumi Maesaki, Yoshio Takesue, Kazunori Tomono, Jun-Ichi Kadota, Mitsuo Kaku, Yoshitsugu Miyazaki, Katsuhiko Kamei, Kazutoshi Shibuya, Yoshitiho Niki, Minoru Yoshida, Yoshihiro Sei
The Epidemiological Investigation Committee for Human Mycoses in Japan performed a retrospective epidemiological survey of candidemia and causative Candida species. Data from 2003 to 2014 were collected from 10 Japanese university hospitals. A total of 328,318 blood cultures were included. The prevalence of fungi in all cultures and in positive cultures were 0.58±0.09% and 4.46±0.66%, respectively. Among the results that were positive for Candida species (N=1,921), Candida albicans was the most common species (39...
2018: Medical Mycology Journal
https://www.readbyqxmd.com/read/29491337/-ultrastructural-patterns-of-interactions-between-murine-lung-macrophages-and-yeast-cells-of-cryptococcus-neoformans-strains-with-different-virulence
#7
Amaliya Stepanova, Natalia Vasilyeva, Masashi Yamaguchi, Hiroji Chibana, Iliya Bosak, Larisa Filippova
This article presents the ultrastructural patterns of interactions between the murine lung macrophages and cells of low- (RKPGY-881, -1165, -1178) and high-virulence (RKPGY-1090, -1095, -1106) strains of Cryptococcus neoformans at the seventh post-experimental day. It was found that if macrophages ingest living yeast cells, the latter can: 1) become completely free from polysaccharide capsules, after that their contents undergo lysis, and cell wall debris are extruded from the macrophage (first scenario); 2) become partly free from their capsules, destroy the phagosomal plasma membrane and induce destructive processes inside the macrophage causing their death (second scenario); or 3) not lose their capsules and localize inside macrophage in latent state (third scenario)...
2018: Medical Mycology Journal
https://www.readbyqxmd.com/read/29187723/-term-16
#8
(no author information available yet)
No abstract text is available yet for this article.
2017: Medical Mycology Journal
https://www.readbyqxmd.com/read/29187722/-the-plasma-1%C3%A2-3-%C3%AE-d-glucan-assay-a-japanese-contribution-to-the-diagnosis-of-invasive-fungal-infection
#9
Taminori Obayashi
 In 1985, a (1→3)-β-D-glucan assay based on the discovery of a (1→3)-β-D-glucan-sensitive coagulation factor in the horseshoe crab amebocytes was developed in Japan, as a test aid in the diagnosis of invasive fungal infections. After many clinical trials, it has now been incorporated in practice guidelines both in Japan and abroad for the diagnosis and management of invasive fungal infection, and is now available worldwide. In Japan, however, two commercial kits that differ widely in sensitivity to (1→3)-β-D-glucan are used; namely, the colorimetric and the turbidimetric assays...
2017: Medical Mycology Journal
https://www.readbyqxmd.com/read/29187721/-survival-strategies-of-aspergillus-in-the-human-body
#10
Masato Tashiro, Koichi Izumikawa
 The human body is a hostile environment for Aspergillus species, which originally live outside the human body. There are lots of elimination mechanisms against Aspergillus inhaled into the human body, such as high body temperature, soluble lung components, mucociliary clearance mechanism, or responses of phagocytes. Aspergillus fumigatus, which is the primary causative agent of human infections among the human pathogenic species of Aspergillus, defend itself from the hostile human body environment by various mechanisms, such as thermotolerance, mycotoxin production, and characteristic morphological features...
2017: Medical Mycology Journal
https://www.readbyqxmd.com/read/29187720/-histopathological-diagnosis-of-fungal-sinusitis-and-variety-of-its-etiologic-fungus
#11
Masatomo Kimura
 Fungal sinusitis is divided into two categories depending on mucosal invasion by fungus, i.e., invasive and noninvasive. Invasive fungal sinusitis is further divided into acute and chronic disease based on time course. Noninvasive fungal sinusitis includes chronic noninvasive sinusitis (fungal ball type) and allergic fungal sinusitis. Chronic noninvasive sinusitis is the most predominant fungal sinusitis in Japan, followed by allergic fungal sinusitis. Invasive fungal sinusitis is rare. Hyphal tissue invasion is seen in invasive fungal sinusitis...
2017: Medical Mycology Journal
https://www.readbyqxmd.com/read/29187719/-small-animal-aspergillosis-and-cryptococcosis-in-japan
#12
Rui Kano
 Canine and feline upper respiratory tract (URT) infection due to Aspergillus spp. is considered an emerging disease, with the number of reported cases continuing to rise in Japan. Aspergillus fumigatus has been the most frequently reported etiologic agent of sino-orbital aspergillosis in dogs and cats; the other Aspergillus species, Aspergillus felis, Aspergillus fischeri, Aspergillus udagawae, Aspergillus viridinutans, and A. fumigatus, have also been implicated in feline cases. The minimum inhibitory concentrations (MICs) of antifungal drugs are elevated for these cryptic species compared with A...
2017: Medical Mycology Journal
https://www.readbyqxmd.com/read/29187718/-affinity-of-luliconazole-for-human-nail-derived-keratin
#13
Masayuki Hasuko, Ryo Shiomi, Yoshinori Takahashi, Kazuhiko Motoba, Hirofumi Hirano, Ryoji Tsuboi, Katsuhiro Inagaki
 Affinity of Luliconazole (LLCZ), an antifungal drug used for topical treatment of onychomycosis in Japan, to nail keratin was demonstrated. Efinaconazole (EFCZ) was used as a reference drug. Drugs at fixed concentrations were added to 4 ml of buffer solution containing 40 mg of nail keratin powder prepared from healthy volunteers or from tinea unguium patients. The mixtures were shaken at 37℃, and adsorption and desorption rates of the drug in nail keratin were measured. Theoretical analysis using the Freundlich adsorption isotherm was applied to eliminate effects of testing conditions on the results...
2017: Medical Mycology Journal
https://www.readbyqxmd.com/read/29187717/-a-case-of-liver-dysfunction-requiring-hospital-admission-after-taking-oral-itraconazole-for-the-treatment-of-kerion-celsi
#14
Eri Ikeda, Soko Watanabe, Mizuki Sawada, Junya Ninomiya, Itaru Dekio, Sumiko Ishizaki, Mariko Fujibayashi, Masaru Tanaka, Takashi Harada
  67-year-old female patient developed drug-induced liver dysfunction after taking oral itraconazole (ITCZ) for the treatment of kerion celsi. Red papules appeared on the temporal area of the patient one month prior to her visit to our clinic. The patient presented with a nodule with yellow crust, erosion, infiltration, and hair loss on the area. Diagnosis of kerion celsi caused by Trichophyton rubrum was made from clinical, pathological, and mycological findings. Laboratory data showed normal liver function, and the patient was not taking any other medication, thus, daily oral ITCZ 100 mg was started...
2017: Medical Mycology Journal
https://www.readbyqxmd.com/read/29187716/-possible-involvement-of-surface-antigen-protein-2-in-the-morphological-transition-and-biofilm-formation-of-candida-albicans
#15
Kazuko Okamoto-Shibayama, Yuichiro Kikuchi, Eitoyo Kokubu, Kazuyuki Ishihara
Surface antigen protein 2 (Csa2) is a member of the Candida albicans Common in Fungal Extracellular Membranes (CFEM) protein superfamily. We previously established its role in iron acquisition in C. albicans. However, the other roles of Csa2 remain unknown. Here, we compared growth, morphological transition, and biofilm formation among wild-type, Csa2-mutant, and complemented strains of C. albicans. Deletion of the Csa2 gene resulted in smaller and reduced colony growth, significant attenuation of the dimorphic transition under serum-inducing conditions, and reduced biofilm formation; complementation restored these levels to those of the wild-type...
2017: Medical Mycology Journal
https://www.readbyqxmd.com/read/29187715/-a-silkworm-infection-model-to-evaluate-antifungal-drugs-for-cryptococcosis
#16
Yasuhiko Matsumoto, Masaki Ishii, Kiminori Shimizu, Susumu Kawamoto, Kazuhisa Sekimizu
The development of effective drugs against fungal diseases involves performing infection experiments in animals to evaluate candidate therapeutic compounds. Cryptococcus neoformans is a pathogenic fungus that causes deep mycosis, resulting in respiratory illness and meningitis. Here we describe a silkworm system established to evaluate the safety and efficacy of therapeutic drugs against infection by Cryptococcus neoformans and the advantages of this system over other animal models. The silkworm assay system has two major advantages: 1) silkworms are less expensive to rear and their use is less problematic than that of mammals in terms of animal welfare, and 2) in vivo screenings for identifying candidate drugs can be easily performed using a large number of silkworms...
2017: Medical Mycology Journal
https://www.readbyqxmd.com/read/29187714/-preparation-and-biological-characterization-of-limulus-factor-g-activating-substance-of-aspergillus-spp
#17
Yuichiro Kurone, Ken-Ichi Ishibashi, Daisuke Yamanaka, Noriko N Miura, Yoshiyuki Adachi, Naohito Ohno
Aspergillus is a medically important fungal genus that causes a life-threatening infection known as aspergillosis in immunocompromised patients. β-1,3-Glucan is detected in the plasma of patients with aspergillosis and appears to be useful for the diagnosis of aspergillosis. In this study, we cultured Aspergillus spp. in a chemically defined liquid medium and prepared an Aspergillus water-soluble fraction (ASWS) from the culture supernatants. ASWS was found to be primarily composed of polysaccharides and proteins...
2017: Medical Mycology Journal
https://www.readbyqxmd.com/read/28855487/erratum
#18
(no author information available yet)
No abstract text is available yet for this article.
2017: Medical Mycology Journal
https://www.readbyqxmd.com/read/28855486/term-15
#19
(no author information available yet)
No abstract text is available yet for this article.
2017: Medical Mycology Journal
https://www.readbyqxmd.com/read/28855485/potential-of-next-generation-poct-in-infectious-disease-rapid-test
#20
REVIEW
Naoto Shimetani
Real-time test results are necessary for early diagnosis and in determining treatment orientation in medical practice. Point of Care Testing (POCT) is a testing system that provides beneficial and helpful information for diagnosis and treatment through real-time testing at the bedside. Therefore, POCT has high utility value in the field of infectious diseases as a rapid test that provides, within the consultation hours, useful information for initial treatment.Infectious disease rapid test kits are commercially available for a wide variety of prophlogistic pathogen targets, including bacterial, viral, fungal, protozoal, and other disease agents...
2017: Medical Mycology Journal
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