Marius Papurica, Alexandru Florin Rogobete, Dorel Sandesc, Raluca Dumache, Radu Nartita, Mirela Sarandan, Alina Carmen Cradigati, Loredana Luca, Corina Vernic, Ovidiu Horea Bedreag
The critically ill polytrauma patient is a constant challenge for the trauma team due to the complexity of the complications presented. Intense inflammatory response and infections, as well as multiple organ dysfunctions, significantly increase the rate of morbidity and mortality in these patients. Moreover, due to the physiological and biochemical imbalances present in this type of patients, the bioproduction of free radicals is significantly accelerated, thus installing the oxidative stress. In the therapeutic management of such patients, multiple surgical interventions are required and therefore they are being subjected to repeated general anesthesia...
2015: Molecular Biology International