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Asia Pacific Allergy

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https://www.readbyqxmd.com/read/29094023/absence-of-esophageal-eosinophilia-in-a-toddler-with-severe-eosinophilic-esophagitis
#1
Wenyin Loh, Karen Michelle Wright, Fang Kuan Chiou
Eosinophilic esophagitis (EoE) is a clinicopathologic disease characterised by esophageal dysfunction and eosinophil-predominant inflammation. Diagnosing EoE in children is particularly challenging as they tend to present with nonspecific symptoms and their mucosal specimens may have less than the threshold number of eosinophils. Reluctance to subject children to multiple endoscopic procedures and anesthesia often results in treatment with a proton pump inhibitor (PPI) first to evaluate clinical response. This approach presents a problem as a diagnosis of EoE may be missed...
October 2017: Asia Pacific Allergy
https://www.readbyqxmd.com/read/29094022/evaluation-of-the-results-of-oral-food-challenges-conducted-in-specialized-and-general-hospitals
#2
Kazunori Sakai, Kemal Sasaki, Tomoko Furuta, Shiro Sugiura, Yukari Watanabe, Takae Kobayashi, Takashi Kawabe, Masashi Morishita, Kumiko Nakanishi, Komei Ito
Background: Oral food challenge (OFC) tests are conducted in both specialized institutions and general hospitals. We aimed to compare the severity of the conditions of the patients between these 2 types of institutions in order to consider the role of such institutions in society. Objective: We evaluated the results of OFC tests for hen's egg, cow's milk, and wheat that were conducted in a specialized institution (Aichi Children's Health and Medical Center [ACHMC], n = 835) and in 4 general hospitals (n = 327) in Aichi prefecture, Japan...
October 2017: Asia Pacific Allergy
https://www.readbyqxmd.com/read/29094021/the-asthma-and-chronic-obstructive-pulmonary-disease-overlap-syndrome-in-tertiary-care-setting-thailand
#3
Theerasuk Kawamatawong, Sanruethai Charoenniwassakul, Ticha Rerkpattanapipat
Background: Asthma and chronic obstructive pulmonary disease (COPD) overlap syndrome (ACOS) is an increasingly recognized clinical entity. ACOS significantly impacts on patient outcome compared to isolated asthma or COPD. However, ACOS definition and diagnosis criteria have not been well standardized. ACOS prevalence and clinical features in Thailand has never been studied. Objective: To investigate the prevalence and clinical features of ACOS compared to isolated asthma or COPD among patients with clinician-diagnosis of obstructive airway diseases...
October 2017: Asia Pacific Allergy
https://www.readbyqxmd.com/read/29094020/basophils-are-increased-and-express-increased-levels-of-interleukin-4-in-the-parotid-lesions-of-kimura-disease
#4
Manabu Nonaka, Eri Sakitani, Erika Ono, Yukie Yamamura, Yukako Seo, Noriyuki Shibata, Ruby Pawankar, Toshio Yoshihara
Background: Kimura disease (KD) is a systemic soft-tissue disease that leads to formation of painless masses in lymph nodes, with the highest predilection for the head and neck and especially the parotid gland. KD lesions are characterized by marked eosinophil infiltration, production of IgE and increased expression of T-helper type 2 (Th2) cytokines (interleukin [IL]-4, IL-5, etc.). Skewing to a Th2 inflammation is also demonstrated in the peripheral blood, with elevated eosinophils and high IgE levels...
October 2017: Asia Pacific Allergy
https://www.readbyqxmd.com/read/29094019/serum-25-hydroxyvitamin-d-inversely-associated-with-blood-eosinophils-in-patients-with-persistent-allergic-rhinitis
#5
Hai-Yan Wu, Jin-Xiang Chen, Hui-Qin Tian, Xiu-Ling Zhang, Hai-Yan Bian, Lei Cheng
Objective: The relationship between vitamin D and allergic rhinitis (AR) remains unclear. The present study investigated their association by examining serum 25-hydroxyvitamin D (25(OH)D) levels, blood eosinophils, and the expression of vitamin D receptors (VDR) on nasal mucosa in patients with AR. Methods: A total of 32 patients with persistent AR and 25 controls were enrolled in this study. Serum 25(OH)D levels were detected by enzyme-linked immunosorbent assay, and eosinophils in the peripheral blood were examined by an automated hematology system, while VDR expression on inferior turbinate mucosa was assessed by immunohistochemistry...
October 2017: Asia Pacific Allergy
https://www.readbyqxmd.com/read/29094018/comparison-of-nasal-cytokine-profiles-of-human-metapneumovirus-and-respiratory-syncytial-virus
#6
Jin-Sung Park, Young-Ho Kim, Eunmi Kwon, Zak Callaway, Takao Fujisawa, Chang-Keun Kim
Background: Human metapneumovirus (hMPV) and respiratory syncytial virus (RSV) share some epidemiological and clinical characteristics; however, few studies have examined the mechanisms by which these viruses induce airway inflammation. Objective: This study was undertaken to compare cytokine profiles in hMPV and RSV patients to investigate possible differences in inflammatory pathways. Methods: Nasopharyngeal aspirate specimens were collected from 1,008 pediatric patients hospitalized for acute lower respiratory tract infection with wheezing and 20 normal healthy controls...
October 2017: Asia Pacific Allergy
https://www.readbyqxmd.com/read/29094017/frequency-and-effect-of-type-1-hypersensitivity-in-patients-from-india-with-chronic-obstructive-pulmonary-disease-and-associated-upper-airways-symptoms
#7
Avi Kumar, Shekhar Kunal, Ashok Shah
Background: Chronic obstructive pulmonary disease (COPD) is now recognized as a systemic disorder with many comorbidities. Atopy in patients with COPD and upper airways symptoms has not been characterized. Objective: We investigated the occurrence and impact of aeroallergen sensitisation in patients with COPD and upper airways symptoms. Methods: All 41 subjects with COPD diagnosed as per Global Initiative for Chronic Obstructive Lung Disease guidelines, underwent spirometry with reversibility, computed tomography of the paranasal sinuses (CT-PNS), skin prick test (SPT) against common aeroallergens and responded to St...
October 2017: Asia Pacific Allergy
https://www.readbyqxmd.com/read/29094016/an-epidemic-of-thunderstorm-asthma-in-melbourne-2016-asthma-rhinitis-and-other-previous-allergies
#8
Kanishka B Rangamuwa, Alan C Young, Francis Thien
Background: On 21st November 2016, Melbourne experienced an epidemic of 'thunderstorm asthma.' Although previously described in the literature, risk factors and natural history remain incompletely understood. Objective: Our aim was to follow up those presenting to the 3 Emergency Departments (EDs) in our health service during the epidemic, and assess their history for previous asthma, rhinitis, and allergies. Methods: ED notes of all respiratory presentations within 48 hours of the thunderstorm event were reviewed and patients with acute asthma included...
October 2017: Asia Pacific Allergy
https://www.readbyqxmd.com/read/29094015/respiratory-allergies-in-the-elderly-findings-from-the-korean-longitudinal-study-on-health-and-aging-phase-i-study-2005-2006
#9
REVIEW
Woo-Jung Song, Yoon-Seok Chang
Population aging is a global issue, but is estimated to be more rapid and dramatic in Asian countries. In the past, allergy might have been a minor concern in the elderly (usually defined as ≥65 years). However, recent series of epidemiologic studies indicate that allergic diseases are more prevalent than expected in the aged population. Furthermore, they pose significant impact on quality of life and socioeconomic costs. The burden may also increase in the elderly, due to frequent comorbidities and treatment-related complications...
October 2017: Asia Pacific Allergy
https://www.readbyqxmd.com/read/29094014/autumn-leaves-about-aging-and-allergy
#10
EDITORIAL
Yoon-Seok Chang
No abstract text is available yet for this article.
October 2017: Asia Pacific Allergy
https://www.readbyqxmd.com/read/28765824/is-nonhomogeneous-expression-of-tissue-mast-cells-or-allergen-specific-iges-bound-to-tissue-mast-cells-possible
#11
Murat Türk, Sakine Nazik Bahçecioğlu, İnsu Yılmaz
Skin prick tests (SPTs) are widely used to demonstrate an IgE-mediated hypersensitivity reaction to a specific allergen. However, local allergic conditions cannot be diagnosed with SPTs. Local specific IgE production was only presented before in mucosal tissues. We present a patient with house dust mite sensitization that had variable SPTs results in different body regions.
July 2017: Asia Pacific Allergy
https://www.readbyqxmd.com/read/28765823/past-present-and-future-of-pharmacovigilance-in-korea
#12
REVIEW
Dong Yoon Kang, Kyung-Min Ahn, Hye-Ryun Kang, Sang-Heon Cho
As an essential part of patient safety, pharmacovigilance is of worldwide interest and should expand its scope and focus on new emerging issues. South Korea has been making continuous efforts in the field of pharmacovigilance for the last 3 decades since voluntary adverse drug reaction (ADR) reporting system was first launched in 1988. Korea joined the World Health Organization Program for International Drug Monitoring in 1992, and the activities of Pharmacovigilance Research Network, Korean Society for Pharmacoepidemiology and Risk Management, and Regional Pharmacovigilance Center (RPVC) have contributed to the remarkable progress in the pharmacovigilance area and global status...
July 2017: Asia Pacific Allergy
https://www.readbyqxmd.com/read/28765822/is-euxyl-k400-patch-testing-useful-in-the-general-population
#13
Ariel Callero, Eva Perez-Rodriguez, Felipe Heras-Mendaza, Juan Antonio Martinez-Tadeo, Jose Carlos Garcia-Robaina, Luis Conde-Salazar
No abstract text is available yet for this article.
July 2017: Asia Pacific Allergy
https://www.readbyqxmd.com/read/28765821/increased-antioxidant-activity-after-exposure-of-ozone-in-murine-asthma-model
#14
Yang Ki Kim, So My Koo, Kiup Kim, Soo-Taek Uh, Ahnsoo Jang, Choon-Sik Park
BACKGROUND: Ozone is well known as an important component of ambient air pollutants. Ozone can aggravate respiratory symptoms in patients with bronchial asthma, but, not in healthy person. We hypothesized asthma itself may show different response to ozone compared to nonasthma. OBJECTIVE: This study was performed to evaluate the differences of response to ozone between normal and asthmatic mice model in terms of status of oxidant injury and antioxidant activity...
July 2017: Asia Pacific Allergy
https://www.readbyqxmd.com/read/28765820/self-report-prevalence-and-associated-factors-to-drug-hypersensitivity-in-mexican-young-adults
#15
Martín Bedolla-Barajas, Cecilia Puente-Fernández, Miriam V Flores-Merino, Jaime Morales-Romero, Ma Victoria Domínguez-García
BACKGROUND: Drug hypersensitivity is defined as any unfavorable reaction that occurs after the administration of any drug. It may or may not be mediated by the involvement of the immune system. Epidemiological data related to drug hypersensitivity reactions in our country are scarce. OBJECTIVE: To determine the prevalence of drug hypersensitivity in a group of young adults, as well as to identify associated factors. METHODS: A structured questionnaire was applied to young people aged 18 to 25 years...
July 2017: Asia Pacific Allergy
https://www.readbyqxmd.com/read/28765819/a-review-of-42-asthmatic-children-with-allergic-bronchopulmonary-aspergillosis
#16
Ashok Shah, Shekhar Kunal
BACKGROUND: Allergic bronchopulmonary aspergillosis (ABPA) in children with asthma, not associated with cystic fibrosis, is yet to receive the recognition it deserves. OBJECTIVE: To highlight the presentation of ABPA in children with asthma. METHODS: This retrospective review documents the occurrence of pediatric ABPA over a period of 31 years in one unit. Children with asthma, eosinophilia and infiltrates on chest radiograph were screened for ABPA...
July 2017: Asia Pacific Allergy
https://www.readbyqxmd.com/read/28765818/characteristics-of-airborne-pollen-in-incheon-and-seoul-2015-2016
#17
Hye Ju So, Soon Jeong Moon, Seon Yeong Hwang, Jeong Hee Kim, Hae Ji Jang, Jung Heum Jo, Tae Jung Sung, Dae Hyun Lim
BACKGROUND: Pollen allergens are one of the main contributors to the development and/or aggravation of allergic rhinitis, allergic conjunctivitis, and asthma. OBJECTIVE: An examination of the airborne pollen in residential areas should be conducted to aid the diagnosis and treatment of allergic diseases. METHODS: Airborne pollen samples were collected from 2 sites in Incheon and 2 in Seoul from 2015 to 2016. RESULTS: The highest monthly concentration of airborne pollen was observed in May and September each year...
July 2017: Asia Pacific Allergy
https://www.readbyqxmd.com/read/28765817/allergen-specific-intralymphatic-immunotherapy-in-human-and-animal-studies
#18
REVIEW
Seon Tae Kim, So Hyun Park, Sang Min Lee, Sang Pyo Lee
Clinical trials of intralymphatic immunotherapy (ILIT) have been performed to overcome the limitations of long-term therapy and the local or systemic hypersensitivity reactions in conventional allergen-specific immunotherapy, including subcutaneous or sublingual immunotherapy. Additionally, several animal studies of ILIT have been conducted in the form of translational or veterinary research. We conducted a literature review to examine the treatment efficacy and adverse effects of ILIT.
July 2017: Asia Pacific Allergy
https://www.readbyqxmd.com/read/28765816/classification-of-chronic-rhinosinusitis-according-to-a-nasal-polyp-and-tissue-eosinophilia-limitation-of-current-classification-system-for-asian-population
#19
REVIEW
Sung-Woo Cho, Dae Woo Kim, Jeong-Whun Kim, Chul Hee Lee, Chae-Seo Rhee
Chronic rhinosinusitis (CRS) can be classified according to the presence of a nasal polyp (NP): CRS with NP (CRSwNP) and CRS without NP (CRSsNP). CRSwNP has characteristics with high infiltration of tissue eosinophilia with a burst of Th2 inflammatory cytokine. However recent findings in Eastern Asia countries suggest that CRSwNP can be divided according to the presence of tissue eosinophilia. Thus, CRSwNP can be classified into eosinophilic and noneosinophilic. Eosinophilic CRSwNP seems to have different immunological and clinical feature compared to noneosinophilic CRSwNP...
July 2017: Asia Pacific Allergy
https://www.readbyqxmd.com/read/28765815/aerobiology-in-asian-airway-allergic-diseases
#20
EDITORIAL
Bernard Yu-Hor Thong
No abstract text is available yet for this article.
July 2017: Asia Pacific Allergy
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