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Asia Pacific Allergy

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https://www.readbyqxmd.com/read/28154807/hypersensitivity-to-ticagrelor-and-low-response-to-clopidogrel-a-case-report
#1
Jing Dai, Shuzheng Lyu, Changjiang Ge
Ticagrelor is widely used to treat acute coronary syndrome. Hypersensitivity reaction of ticagrelor is rarely recognized. A low response to clopidogrel, which occurs in up to 23% of patients, is an independent risk factor for stent thrombosis. Management of patients with a low response to clopidogrel and ticagrelor hypersensitivity who are undergoing antithrombotic therapy remains to be a challenge. Herein, we report a patient with low response to clopidogrel and ticagrelor hypersensitivity, who was successfully managed using aspirin and warfarin...
January 2017: Asia Pacific Allergy
https://www.readbyqxmd.com/read/28154806/anaphylaxis-caused-by-honey-a-case-report
#2
Rita Aguiar, Fátima Cabral Duarte, Ana Mendes, Borja Bartolomé, Manuel Pereira Barbosa
Honey allergy is a very rare, but serious health condition. In this study, we presented 1 patient who had anaphylaxis after the honey allergological investigation with skin prick-prick test with honey. Honey as a food has been associated to allergic reactions and as the increased consumption of honey in health food may increase the incidence of honey-related allergic reactions.
January 2017: Asia Pacific Allergy
https://www.readbyqxmd.com/read/28154805/the-impact-of-age-on-pru-p-3-ige-production-in-italy
#3
Giorgio Ciprandi, Mara De Amici, Maria Luisa Di Martino, Fiorella Barocci, Paola Comite
BACKGROUND: Pollen allergy may be frequently associated with fruit-vegetables: the so-called pollen food syndrome. Pru p 3 is the most relevant peach allergen. Previously, it has been reported that serum specific IgE level to Pru p 3 depends on age in a limited geographic area. OBJECTIVE: This study aimed to to test the hypothesis about the differences of Pru p 3 sensitization across Italy, mainly concerning the impact of age. METHODS: The current study was retrospective and multicentre, involving 2 labs in Northern Italy (709 subjects), 1 in Genoa (1,040 subjects), and 1 in Southern Italy (2,188 subjects)...
January 2017: Asia Pacific Allergy
https://www.readbyqxmd.com/read/28154804/administration-of-the-adrenaline-auto-injector-at-the-nursery-kindergarten-school-in-western-japan
#4
Seigo Korematsu, Michiko Fujitaka, Mika Ogata, Masafumi Zaitsu, Chikako Motomura, Kazuyo Kuzume, Yuchiro Toku, Masanori Ikeda, Hiroshi Odajima
BACKGROUND: In view of the increasing prevalence of food allergies, there has been an associated increase in frequency of situations requiring an emergency response for anaphylaxis at the home, childcare facilities and educational institutions. OBJECTIVE: To clarify the situation of adrenaline auto-injector administration in nursery/kindergarten/school, we carried out a questionnaire survey on pediatric physicians in Western Japan. METHODS: In 2015, self-reported questionnaires were mailed to 421 physicians who are members of the West Japan Research Society Pediatric Clinical Allergy and Shikoku Research Society Pediatric Clinical Allergy...
January 2017: Asia Pacific Allergy
https://www.readbyqxmd.com/read/28154803/involvement-of-cross-reactive-carbohydrate-determinants-specific-ige-in-pollen-allergy-testing
#5
Hidenori Yokoi, Hiroshi Yoshitake, Yuma Matsumoto, Michitsugu Kawada, Yoshiki Takato, Kiyomi Shinagawa, Hiroyuki Sakurai, Koichiro Saito
BACKGROUND: Specific IgE antibodies against the low-molecular-weight carbohydrate antigen that does not bridge IgE molecules on mast cells are not associated with clinical symptoms. Cross reactivity can be determined in allergen-specific IgE detection assays when the carbohydrate structures between pollen allergens and plant derived food allergens are similar; in such cases, false positive results for grain or legume allergens can be reported for pollen allergic patients who are not sensitized to those allergens...
January 2017: Asia Pacific Allergy
https://www.readbyqxmd.com/read/28154802/the-transition-of-sputum-inflammatory-cell-profiles-is-variable-in-stable-asthma-patients
#6
Bomi Shin, Hyouk-Soo Kwon, So Young Park, Tae-Bum Kim, Hee-Bom Moon, You Sook Cho
BACKGROUND: The sputum inflammatory cell profile is an important indicator for classifying asthma phenotypes. OBJECTIVE: To investigate if sputum inflammatory cell profile remains stable and there are different characteristics between groups that show different profile over time in stable asthmatic patients. METHODS: A total of 149 asthmatic patients, who were clinically stable at the time of sputum examination and had undergone sputum analysis twice, were subjected to a detailed review...
January 2017: Asia Pacific Allergy
https://www.readbyqxmd.com/read/28154801/pranlukast-reduces-asthma-exacerbations-during-autumn-especially-in-1-to-5-year-old-boys
#7
Yoshinori Morita, Eduardo Campos Alberto, Shuichi Suzuki, Yoshinori Sato, Akira Hoshioka, Hiroki Abe, Kimiyuki Saito, Toshikazu Tsubaki, Mana Haraki, Akiko Sawa, Yoshio Nakayama, Hiroyuki Kojima, Midori Shigeta, Fumiya Yamaide, Yoichi Kohno, Naoki Shimojo
BACKGROUND: Leukotriene receptor antagonists have been used to prevent virus-induced asthma exacerbations in autumn. Its efficacy, however, might differ with age and sex. OBJECTIVE: This study aimed to investigate whether pranlukast added to usual asthma therapy in Japanese children during autumn, season associated with the peak of asthma, reduces asthma exacerbations. It was also evaluated the effect of age and sex on pranlukast's efficacy. METHODS: A total of 121 asthmatic children aged 1 to 14 years were randomly assigned to receive regular pranlukast or not according to sex, and were divided in 2 age groups, 1-5 years and 6-14 years...
January 2017: Asia Pacific Allergy
https://www.readbyqxmd.com/read/28154800/eosinophilic-esophagitis-current-understanding-and-evolving-concepts
#8
REVIEW
Hamish Philpott, Barry Kweh, Francis Thien
Eosinophilic esophagitis (EoE) is now considered to represent a form of food allergy and this is demonstrated by a response to elimination diet in many patients. A critical additional factor may be an inherent impairment in epithelial barrier integrity, possibly worsened by reflux of gastric contents and improved with proton pump inhibitor (PPI) use. Key clinic challenges are posed by the absence of reliable allergy tests to guide elimination diet, and the subsequent need for invasive endoscopic assessment following empirical food challenge, meaning that corticosteroids will remain the mainstay of therapy for many...
January 2017: Asia Pacific Allergy
https://www.readbyqxmd.com/read/28154799/asia-pacific-allergy-6-years-old
#9
EDITORIAL
Yoon-Seok Chang
No abstract text is available yet for this article.
January 2017: Asia Pacific Allergy
https://www.readbyqxmd.com/read/27803887/immediate-systemic-allergic-reaction-in-an-infant-to-fish-allergen-ingested-through-breast-milk
#10
Takayasu Arima, Eduardo Campos-Alberto, Hiraku Funakoshi, Yuzaburo Inoue, Minako Tomiita, Yoichi Kohno, Naoki Shimojo
This is a rare case report of systemic allergic reaction to fish allergen ingested through breast milk. Mother ate raw fish more than 3 times a week. Her consumption of fish was associated with urticaria and wheeze in an infant via breast-feeding. Fish-specific IgE antibodies were detected by skin prick test but not by in vitro IgE test. This case demonstrates that fish protein ingested by mother can cause an immediate systemic allergic reaction in offspring through breast-feeding. Although fish intake is generally recommended for prevention of allergy, one should be aware that frequent intake of fish by a lactating mother may sensitize the baby and induce an allergic reaction through breast-feeding...
October 2016: Asia Pacific Allergy
https://www.readbyqxmd.com/read/27803886/bepotastine-induced-urticaria-cross-reactive-with-other-antihistamines
#11
Ju Wan Kang, Jaechun Lee
Second-generation antihistamines are widely prescribed for the control of symptoms of allergic inflammation such as itchy hives, coryza, and itchy eyes. In rare circumstances, these drugs might provoke allergic inflammation. Hypersensitivity to bepotastine besilate, a second-generation antihistamine has never been reported. A 17-year-old schoolgirl, whose paroxysmal itchy hives had been controlled with bepotastine, experienced aggravation of the hives. An oral provocation test confirmed her hypersensitivity to bepotastine and cross-reactivity to levocetirizine...
October 2016: Asia Pacific Allergy
https://www.readbyqxmd.com/read/27803885/correlations-of-nasal-responses-to-leukotriene-d4-and-histamine-nasal-provocation-with-quality-of-life-in-allergic-rhinitis
#12
Zheng Zhu, Yanqing Xie, Weijie Guan, Yi Gao, Shu Xia, Xu Shi, Jinping Zheng
BACKGROUND: The symptoms of allergic rhinitis (AR) greatly affect the quality of life (QoL) in the patients with AR. The correlations of nasal response to leukotriene D4 (LTD4) and histamine nasal provocation with health related QoL in AR are not clear. OBJECTIVE: To evaluate the correlations of nasal response to LTD4 and histamine nasal challenge with QoL in AR. METHODS: Patients randomly underwent LTD4 and histamine nasal challenge tests, completed the rhinoconjunctivitis quality of life questionnaire (RQoLQ), and rating the symptom severity score (total symptom score 4, TSS4) in the previous week...
October 2016: Asia Pacific Allergy
https://www.readbyqxmd.com/read/27803884/imidacloprid-inhibits-ige-mediated-rbl-2h3-cell-degranulation-and-passive-cutaneous-anaphylaxis
#13
Linbo Shi, Li Zou, Jinyan Gao, Huaing Xu, Xiaoyun Shi, Hongbing Chen
BACKGROUND: Imidacloprid has been commonly used as a pesticide for crop protection and acts as nicotinic acetylcholine receptor agonists. Little information about the relationship between imidacloprid and allergy is available. OBJECTIVE: This study aims to examine the effects of imidacoprid on IgE-mediated mast cell activation. METHODS: The rat basophilic leukemia cell line RBL-2H3 (RBL-2H3 cells) were treated with 10(-3) - 10(-12) mol/L imidacloprid, followed by measuring the mediator production, influx of Ca(2+) in IgE-activated RBL-2H3 cells, and the possible effects of imidacoprid on anti-dinitrophenyl IgE-induced passive cutaneous anaphylaxis (PCA)...
October 2016: Asia Pacific Allergy
https://www.readbyqxmd.com/read/27803883/autologous-serum-and-plasma-skin-test-to-predict-2-year-outcome-in-chronic-spontaneous-urticaria
#14
Tadech Boonpiyathad, Atik Sangasapaviliya
BACKGROUND: Autologous serum skin test (ASST) and autologous plasma skin test (APST) are simple methods to diagnose autoimmune chronic urticaria. However, the association data of ASST or APST with disease severity and long-term outcome are still unclear. OBJECTIVE: The results of ASST and APST might be used to predict urticaria symptom severity and long-term outcomes among chronic spontaneous urticaria (CSU) patients. METHODS: We evaluated the prevalence of reactive ASST and APST in 128 CSU patients...
October 2016: Asia Pacific Allergy
https://www.readbyqxmd.com/read/27803882/pale-nasal-mucosa-affects-airflow-limitations-in-upper-and-lower-airways-in-asthmatic-children
#15
Chikako Motomura, Hiroshi Odajima, Atsunobu Yamada, Naohiko Taba, Yoko Murakami, Sankei Nishima
BACKGROUND: Severe asthmatics are thought to have severer rhinitis than mild asthmatics. A pale nasal mucosa is a typical clinical finding in subjects with severe allergic rhinitis. OBJECTIVE: The aim of this study was to investigate whether a pale nasal mucosa affects airflow limitations in the upper and lower airways in asthmatic children. METHODS: Rhinomanometry, nasal scraping, and spirometry were performed in 54 asthmatic children (median age, 10 years)...
October 2016: Asia Pacific Allergy
https://www.readbyqxmd.com/read/27803881/family-quality-of-life-among-families-of-children-with-atopic-dermatitis
#16
Hae Ji Jang, Seonyeong Hwang, Youngmee Ahn, Dae Hyun Lim, Min Sohn, Jeong Hee Kim
BACKGROUND: Atopic dermatitis (AD) may cause emotional distress and impairs the quality of life (QoL) in children and their families. OBJECTIVE: We examined family QoL of children with AD and explored associated factors such as disease severity and psychosocial factors among parents of children with AD. METHODS: Study participants were 78 children (1 month to 16 years old) diagnosed with AD and their parents visiting an outpatient clinic of the Department of Pediatrics in Inha University Hospital...
October 2016: Asia Pacific Allergy
https://www.readbyqxmd.com/read/27803880/the-ingestion-of-cow-s-milk-formula-in-the-first-3-months-of-life-prevents-the-development-of-cow-s-milk-allergy
#17
Tetsuhiro Sakihara, Shiro Sugiura, Komei Ito
BACKGROUND: IgE-mediated cow's milk allergy (CMA) is one of the most common food allergies in infants. It is still controversial whether the early introduction of cow's milk formula (CMF) prevents the development of CMA. OBJECTIVE: We aimed to evaluate the duration and frequency of CMF ingestion as compere with exclusive breast-fed for preventing CMA in high-risk infants. METHODS: We enrolled the patients diagnosed with hen's egg allergy by an oral food challenge...
October 2016: Asia Pacific Allergy
https://www.readbyqxmd.com/read/27803879/chronic-cough-in-korean-adults-a-literature-review-on-common-comorbidity
#18
REVIEW
Sung-Yoon Kang, Gun-Woo Kim, Woo-Jung Song, Yoon-Seok Chang, Sang-Heon Cho
Chronic cough is a significant medical condition with high prevalence and a strong negative impact on the quality of life. Cough hypersensitivity is thought to underlie chronic cough, with several environmental and host factors interacting to cause neuronal sensitization and chronicity. Comorbid conditions affecting cough reflex pathways, such as upper airway diseases, asthma, and gastroesophageal reflux, play important roles in chronic cough. However, their prevalence may vary in patients living in different geographical regions or with different ethnicities...
October 2016: Asia Pacific Allergy
https://www.readbyqxmd.com/read/27803878/greetings-from-asia-pacific-allergy
#19
EDITORIAL
Yoon-Seok Chang
No abstract text is available yet for this article.
October 2016: Asia Pacific Allergy
https://www.readbyqxmd.com/read/27489793/marking-nut-anaphylaxis
#20
Jie Shen Fok, Anita Christine Kral, John Hayball, William B Smith
Marking nut Semecarpus anacardium, so-called because it contains a pigment that has been used in the past to mark fabrics, is a known cause of contact hypersensitivity. It may be ingested as an ingredient of some traditional Hindi foods. We describe the first reported case of anaphylaxis to marking nut.
July 2016: Asia Pacific Allergy
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