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Asia Pacific Allergy

Takayasu Arima, Eduardo Campos-Alberto, Hiraku Funakoshi, Yuzaburo Inoue, Minako Tomiita, Yoichi Kohno, Naoki Shimojo
This is a rare case report of systemic allergic reaction to fish allergen ingested through breast milk. Mother ate raw fish more than 3 times a week. Her consumption of fish was associated with urticaria and wheeze in an infant via breast-feeding. Fish-specific IgE antibodies were detected by skin prick test but not by in vitro IgE test. This case demonstrates that fish protein ingested by mother can cause an immediate systemic allergic reaction in offspring through breast-feeding. Although fish intake is generally recommended for prevention of allergy, one should be aware that frequent intake of fish by a lactating mother may sensitize the baby and induce an allergic reaction through breast-feeding...
October 2016: Asia Pacific Allergy
Ju Wan Kang, Jaechun Lee
Second-generation antihistamines are widely prescribed for the control of symptoms of allergic inflammation such as itchy hives, coryza, and itchy eyes. In rare circumstances, these drugs might provoke allergic inflammation. Hypersensitivity to bepotastine besilate, a second-generation antihistamine has never been reported. A 17-year-old schoolgirl, whose paroxysmal itchy hives had been controlled with bepotastine, experienced aggravation of the hives. An oral provocation test confirmed her hypersensitivity to bepotastine and cross-reactivity to levocetirizine...
October 2016: Asia Pacific Allergy
Zheng Zhu, Yanqing Xie, Weijie Guan, Yi Gao, Shu Xia, Xu Shi, Jinping Zheng
BACKGROUND: The symptoms of allergic rhinitis (AR) greatly affect the quality of life (QoL) in the patients with AR. The correlations of nasal response to leukotriene D4 (LTD4) and histamine nasal provocation with health related QoL in AR are not clear. OBJECTIVE: To evaluate the correlations of nasal response to LTD4 and histamine nasal challenge with QoL in AR. METHODS: Patients randomly underwent LTD4 and histamine nasal challenge tests, completed the rhinoconjunctivitis quality of life questionnaire (RQoLQ), and rating the symptom severity score (total symptom score 4, TSS4) in the previous week...
October 2016: Asia Pacific Allergy
Linbo Shi, Li Zou, Jinyan Gao, Huaing Xu, Xiaoyun Shi, Hongbing Chen
BACKGROUND: Imidacloprid has been commonly used as a pesticide for crop protection and acts as nicotinic acetylcholine receptor agonists. Little information about the relationship between imidacloprid and allergy is available. OBJECTIVE: This study aims to examine the effects of imidacoprid on IgE-mediated mast cell activation. METHODS: The rat basophilic leukemia cell line RBL-2H3 (RBL-2H3 cells) were treated with 10(-3) - 10(-12) mol/L imidacloprid, followed by measuring the mediator production, influx of Ca(2+) in IgE-activated RBL-2H3 cells, and the possible effects of imidacoprid on anti-dinitrophenyl IgE-induced passive cutaneous anaphylaxis (PCA)...
October 2016: Asia Pacific Allergy
Tadech Boonpiyathad, Atik Sangasapaviliya
BACKGROUND: Autologous serum skin test (ASST) and autologous plasma skin test (APST) are simple methods to diagnose autoimmune chronic urticaria. However, the association data of ASST or APST with disease severity and long-term outcome are still unclear. OBJECTIVE: The results of ASST and APST might be used to predict urticaria symptom severity and long-term outcomes among chronic spontaneous urticaria (CSU) patients. METHODS: We evaluated the prevalence of reactive ASST and APST in 128 CSU patients...
October 2016: Asia Pacific Allergy
Chikako Motomura, Hiroshi Odajima, Atsunobu Yamada, Naohiko Taba, Yoko Murakami, Sankei Nishima
BACKGROUND: Severe asthmatics are thought to have severer rhinitis than mild asthmatics. A pale nasal mucosa is a typical clinical finding in subjects with severe allergic rhinitis. OBJECTIVE: The aim of this study was to investigate whether a pale nasal mucosa affects airflow limitations in the upper and lower airways in asthmatic children. METHODS: Rhinomanometry, nasal scraping, and spirometry were performed in 54 asthmatic children (median age, 10 years)...
October 2016: Asia Pacific Allergy
Hae Ji Jang, Seonyeong Hwang, Youngmee Ahn, Dae Hyun Lim, Min Sohn, Jeong Hee Kim
BACKGROUND: Atopic dermatitis (AD) may cause emotional distress and impairs the quality of life (QoL) in children and their families. OBJECTIVE: We examined family QoL of children with AD and explored associated factors such as disease severity and psychosocial factors among parents of children with AD. METHODS: Study participants were 78 children (1 month to 16 years old) diagnosed with AD and their parents visiting an outpatient clinic of the Department of Pediatrics in Inha University Hospital...
October 2016: Asia Pacific Allergy
Tetsuhiro Sakihara, Shiro Sugiura, Komei Ito
BACKGROUND: IgE-mediated cow's milk allergy (CMA) is one of the most common food allergies in infants. It is still controversial whether the early introduction of cow's milk formula (CMF) prevents the development of CMA. OBJECTIVE: We aimed to evaluate the duration and frequency of CMF ingestion as compere with exclusive breast-fed for preventing CMA in high-risk infants. METHODS: We enrolled the patients diagnosed with hen's egg allergy by an oral food challenge...
October 2016: Asia Pacific Allergy
Sung-Yoon Kang, Gun-Woo Kim, Woo-Jung Song, Yoon-Seok Chang, Sang-Heon Cho
Chronic cough is a significant medical condition with high prevalence and a strong negative impact on the quality of life. Cough hypersensitivity is thought to underlie chronic cough, with several environmental and host factors interacting to cause neuronal sensitization and chronicity. Comorbid conditions affecting cough reflex pathways, such as upper airway diseases, asthma, and gastroesophageal reflux, play important roles in chronic cough. However, their prevalence may vary in patients living in different geographical regions or with different ethnicities...
October 2016: Asia Pacific Allergy
Yoon-Seok Chang
No abstract text is available yet for this article.
October 2016: Asia Pacific Allergy
Jie Shen Fok, Anita Christine Kral, John Hayball, William B Smith
Marking nut Semecarpus anacardium, so-called because it contains a pigment that has been used in the past to mark fabrics, is a known cause of contact hypersensitivity. It may be ingested as an ingredient of some traditional Hindi foods. We describe the first reported case of anaphylaxis to marking nut.
July 2016: Asia Pacific Allergy
Young Kim, Hong-Yeul Lee, Kang-Mo Gu, Joo-Young Lee, Sang-Won Yoon, Tae-Yeon Park, Jae-Chol Choi, Jae-Yeol Kim, In-Won Park, Jong-Wook Shin, Byoung-Whui Choi, Jae-Woo Jung
Allergic bronchopulmonary aspergillosis (ABPA) is a pulmonary disease with small prevalence. Exposure to aspergillus mold causes immunologic hypersensitivity and may cause ranges of symptoms from minimal to detrimental outcomes. Diagnosing and treating the disease before the development of bronchiectasis may save the patient from poor outcomes. This report presents a case of recurrent ABPA without any symptom of asthma, which impeded the correct diagnosis even after numerous hospitalizations.
July 2016: Asia Pacific Allergy
Theerasuk Kawamatawong, Sitthisak Siripongpun, Ticha Rerkpattanapipat
BACKGROUND: Asthma in the elderly is severe and associated with poor treatment outcome. Although atopy has an important role in pathogenesis, its role in the elderly is unclear, partly due to immune senescence. OBJECTIVE: We aimed to examine the associations of Th2-mediated inflammation with asthma severity in the elderly. METHODS: Consecutive asthmatics older than 60 years without severe exacerbation within 8 weeks were enrolled. Atopic status was determined by positive serum specific IgE or skin prick test to common aeroallergens...
July 2016: Asia Pacific Allergy
Mi-Yeong Kim, Suh-Young Lee, Eun-Jung Jo, Seung-Eun Lee, Min-Gyu Kang, Woo-Jung Song, Sae-Hoon Kim, Sang-Heon Cho, Kyung-Up Min, Ki-Hwan Ahn, Yoon-Seok Chang
BACKGROUND: Asthma patients may experience acute episodic exacerbation. The guidelines recommend that written action plan should be given to asthma patients. However, no one can predict when and where acute exacerbation will happen. As people carry smart phone almost anytime and anywhere, smartphone application could be a useful tool in asthma care. We evaluated the feasibility of the ubiquitous healthcare system of asthma care using a smartphone application (snuCare) based on the self-management guideline or action plan...
July 2016: Asia Pacific Allergy
Lisha Li, Kai Guan
BACKGROUND: Although many patients with allergic rhinitis have symptoms due to sensitization to more than one kind of allergens, and mixed allergen extracts are widely used for immunotherapy, there are few published trials. OBJECTIVE: Our study aimed to evaluate the effect of multiple-allergen immunotherapy on improving the symptoms and quality of life of allergic rhinitis patients. METHODS: We performed a 1-year single-center observation study of subcutaneous immunotherapy using house dust mite extract (n = 12), weed pollen extract (n = 21), or mixed house dust mite/weed pollen extract (n = 11) in 44 allergic rhinitis patients...
July 2016: Asia Pacific Allergy
So-Hee Lee, Heung-Woo Park, Sang-Heon Cho, Sun-Sin Kim
BACKGROUND: Single premedication with antihistamines for radiocontrast media (RCM) hypersensitivity is frequently used in real world at the emergent situation although its efficacy is not proven. OBJECTIVE: To evaluate the effect of intravenous antihistamines as a premedication in general population who had experience of mild adverse reactions to iodinated RCM. METHODS: A retrospective observational study on 14,785 subjects who had RCM-enhanced computed tomography scans between January 2014 and December 2015 in Seoul National University Hospital Gangnam Healthcare Center, Seoul, South Korea...
July 2016: Asia Pacific Allergy
Hong Hui Wong, Jaslyn Jie Lin Lee, Lynette Pei-Chi Shek, Bee Wah Lee, Anne Goh, Oon Hoe Teoh, Peter D Gluckman, Keith M Godfrey, Seang Mei Saw, Kenneth Kwek, Yap Seng Chong, Hugo Ps Van Bever
BACKGROUND: Studies have reported that early febrile episodes and febrile episodes with infections are associated with a decreased risk of developing atopy. OBJECTIVE: To examine further the association between presence of and number of febrile episodes are with atopy and atopic diseases and if there was a difference between all fevers and fever after vaccination. METHODS: We studied 448 infants in a Singapore mother-offspring cohort study (Growing Up in Singapore Towards Healthy Outcomes) which had complete data for the exposures and outcomes of interest...
July 2016: Asia Pacific Allergy
Luciana Kase Tanno, Moises Calderon, Pascal Demoly
BACKGROUND: The new International Classification of Diseases (ICD)-11 "Allergic and hypersensitivity conditions" section has been constructed as a result of a detailed and careful action plan based on scientific evidences for the necessity of changes and collaboration with the World Health Organization (WHO) ICD-11 revision governance. All the efforts are being acknowledged by the Joint Allergy Academies. OBJECTIVE: Considering the new classification model addressed to the allergic and hypersensitivity conditions and following the ICD WHO agenda, we believe it is the appropriate time to start supporting the validation process in collaboration with the WHO ICD governance...
July 2016: Asia Pacific Allergy
Ayfer Yukselen
Allergen-specific immunotherapy (AIT) is the only curative way that can change the immunologic response to allergens and thus can modify the natural progression of allergic diseases. There are some important criteria which contributes significantly on efficacy of AIT, such as the allergen extract used for treatment, the dose and protocol, patient selection in addition to the severity and control of asthma. The initiation of AIT in allergic asthma should be considered in intermittent, mild and moderate cases which coexisting with other allergic diseases such as allergic rhinitis, and in case of unacceptable adverse effects of medications...
July 2016: Asia Pacific Allergy
Yoon-Seok Chang
No abstract text is available yet for this article.
July 2016: Asia Pacific Allergy
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