Rut Bryl, Magdalena Kulus, Artur Bryja, Dominika Domagała, Paul Mozdziak, Paweł Antosik, Dorota Bukowska, Maciej Zabel, Piotr Dzięgiel, Bartosz Kempisty
Heart failure (HF) is an end-stage of many cardiac diseases and one of the main causes of death worldwide. The current management of this disease remains suboptimal. The adult mammalian heart was considered a post-mitotic organ. However, several reports suggest that it may possess modest regenerative potential. Adult cardiac progenitor cells (CPCs), the main players in the cardiac regeneration, constitute, as it may seem, a heterogenous group of cells, which remain quiescent in physiological conditions and become activated after an injury, contributing to cardiomyocytes renewal...
March 5, 2024: Cell & Bioscience