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Clinical Obesity

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https://www.readbyqxmd.com/read/29045079/improvements-in-health-related-quality-of-life-over-3%C3%A2-years-with-liraglutide-3-0%C3%A2-mg-compared-with-placebo-in-participants-with-overweight-or-obesity
#1
R L Kolotkin, B Gabriel Smolarz, H H Meincke, K Fujioka
Previously in the SCALE Obesity and Prediabetes trial, at 1 year, participants with obesity (or overweight with comorbidities) and prediabetes receiving liraglutide 3.0 mg experienced greater improvements in health-related quality of life (HRQoL) than those receiving placebo. The current study extends these findings by examining 3-year changes in HRQoL. HRQoL was assessed using the obesity-specific Impact of Weight on Quality of Life-Lite (IWQOL-Lite) questionnaire, as well as the Short-Form 36 v2 (SF-36) health survey...
October 16, 2017: Clinical Obesity
https://www.readbyqxmd.com/read/29024558/overweight-obesity-and-adiposity-in-survivors-of-childhood-brain-tumours-a-systematic-review-and-meta-analysis
#2
REVIEW
K-W Wang, A Fleming, D L Johnston, S M Zelcer, S R Rassekh, S Ladhani, A Socha, J Shinuda, S Jaber, S Burrow, S K Singh, L Banfield, R J de Souza, L Thabane, M C Samaan
Survivors of childhood brain tumours (SCBT) have increased cardiometabolic risks, but the determinants of these risks are unclear. This systematic review aims to compare the prevalence of overweight and obesity as well as adiposity measures between SCBT and non-cancer controls. The PubMed, EMBASE, MEDLINE, CINAHL and the Cochrane Library databases were searched. The primary outcomes were the prevalence of overweight and obesity based on body mass index. The secondary outcomes were adiposity measures including percent fat mass, waist-to-hip and waist-to-height ratios...
October 11, 2017: Clinical Obesity
https://www.readbyqxmd.com/read/28891142/network-meta-analysis-of-lorcaserin-and-oral-hypoglycaemics-for-patients-with-type-2-diabetes-mellitus-and-obesity
#3
L M Neff, M S Broder, D Beenhouwer, E Chang, E Papoyan, Z W Wang
In addition to weight loss, randomized controlled trials have shown improvement in glycaemic control in patients taking lorcaserin. The aim of this study aim was to compare adding lorcaserin or other glucose lowering medications to metformin on weight and glycaemic control. A systematic review and network meta-analysis of randomized controlled trials were conducted. Included studies (published 1990-2014) were of lorcaserin or glucose lowering medications in type 2 diabetic patients compared to placebo or different active treatments...
September 10, 2017: Clinical Obesity
https://www.readbyqxmd.com/read/28871633/evaluation-of-aintree-loss-a-community-based-multidisciplinary-weight-management-service-outcomes-and-predictors-of-engagement
#4
T Steele, R P Narayanan, M James, J James, N Mazey, J P H Wilding
Aintree LOSS is a community-based, multidisciplinary weight management programme for patients with severe and complex obesity, focusing on a flexible and individualized service with follow-up for up to 2 years. We evaluated all 2472 patients referred to the service between October 2009 and 2013. Demographic data were recorded at baseline, with the Index of Multiple Deprivation (IMD) used to measure socioeconomic deprivation. Weight was recorded at each visit. Mean body mass index at baseline was 45.6 (standard deviation 6...
September 4, 2017: Clinical Obesity
https://www.readbyqxmd.com/read/28871630/changes-in-psychosocial-health-during-a-7-week-paediatric-weight-management-program
#5
J M Tucker, K Howard, K DeLaFuente, A Cadieux, K E Yee
Youth with obesity are at increased risk of psychosocial symptoms; however, little is known regarding the impact of paediatric weight management (PWM) on psychosocial health. The aim of the study was to investigate changes in psychosocial health among children who completed a 7-week PWM program. Participants aged 5 to 16 years with a BMI ≥85th percentile completed a 7-week, family-centred PWM program focused on health behaviour education, exercise and mentored goal setting. The Paediatric Symptom Checklist (PSC) was assessed via parent report to evaluate psychosocial symptoms before and after the program, and subscales were calculated for internalizing (PSC-IS), externalizing (PSC-ES) and attention symptoms (PSC-AS)...
September 4, 2017: Clinical Obesity
https://www.readbyqxmd.com/read/28871628/response-to-stated-conclusion-about-industry-funding-is-opposite-to-what-the-paper-s-data-show-letter-regarding-selective-outcome-reporting-in-obesity-clinical-trials-a-cross-sectional-review
#6
https://www.readbyqxmd.com/read/28849619/stated-conclusion-about-industry-funding-is-opposite-to-what-the-paper-s-data-show-letter-regarding-selective-outcome-reporting-in-obesity-clinical-trials-a-cross-sectional-review
#7
https://www.readbyqxmd.com/read/28841271/who-seeks-bariatric-surgery-psychosocial-functioning-among-adolescent-candidates-other-treatment-seeking-adolescents-with-obesity-and-healthy-controls
#8
C C Call, M J Devlin, I Fennoy, J L Zitsman, B T Walsh, R Sysko
Limited data are available on the characteristics of adolescents with obesity who seek bariatric surgery. Existing data suggest that adolescent surgery candidates have a higher body mass index (BMI) than comparison adolescents with obesity, but the limited findings regarding psychosocial functioning are mixed. This study aimed to compare BMI and psychosocial functioning among adolescent bariatric surgery candidates, outpatient medical-treatment-seeking adolescents with obesity (receiving lifestyle modification), and adolescents in the normal-weight range...
August 25, 2017: Clinical Obesity
https://www.readbyqxmd.com/read/28834246/magnetic-resonance-imaging-reveals-elevated-aortic-pulse-wave-velocity-in-obese-and-overweight-adolescents
#9
J E Caterini, L Banks, G D Wells, B Cifra, C Slorach, B W McCrindle, M Seed
The aortic pulse wave velocity (PWV) measured via cardiac magnetic resonance (CMR) can be used to non-invasively assess changes in arterial stiffness and potential underlying vascular dysfunction. This technique could unmask early arterial dysfunction in overweight and obese youth at risk for cardiovascular disease. We sought to determine the association between vascular stiffness, percentage body fat, body mass index (BMI), and cardiac function in adolescents across the weight spectrum through both CMR and standard applanation tonometry (AT)-based PWV measurements...
August 23, 2017: Clinical Obesity
https://www.readbyqxmd.com/read/28834164/children-s-food-and-satiety-responsiveness-in-association-with-post-prandial-glucose-following-a-standardized-liquid-meal
#10
M A Gowey, P C Chandler-Laney
Children's responsiveness to food cues and satiety may put them at greater risk for obesity; however, little is known about the physiological mechanisms underlying children's responsiveness to food and satiety. The objective of this study was to examine the association between children's post-prandial glucose responses and maternal report of their eating behaviours. A secondary data analysis was conducted using partial correlation analyses adjusted for gender in a sample of children aged 5-10 years and their mothers (N = 28 dyads)...
August 23, 2017: Clinical Obesity
https://www.readbyqxmd.com/read/28815987/health-related-quality-of-life-in-randomized-controlled-trials-of-lorcaserin-for-obesity-management-what-mediates-improvement
#11
R L Kolotkin, R D Crosby, Z Wang
Lorcaserin, plus diet and exercise, has demonstrated significant weight loss and improved cardiometabolic parameters vs. placebo in patients with overweight/obesity in three randomized, placebo-controlled trials. We examined whether lorcaserin is also associated with greater improvements in health-related quality of life (HRQOL) and whether these improvements are wholly attributable to weight loss. Pooled data from Behavioral Modification and Lorcaserin for Overweight and Obesity Management (BLOOM), Behavioral Modification and Lorcaserin Second Study for Obesity Management (BLOSSOM) and BLOOM-Diabetes Mellitus (BLOOM-DM) trials were analysed (n = 5624)...
August 17, 2017: Clinical Obesity
https://www.readbyqxmd.com/read/28801963/a-preliminary-study-of-static-and-dynamic-balance-in-sedentary-obese-young-adults-the-relationship-between-bmi-posture-and-postural-balance
#12
J A do Nascimento, C C Silva, H H Dos Santos, J J de Almeida Ferreira, P R de Andrade
The aim of this study was to evaluate the postural control of obese young adults with normal body mass index during different static (bipedic and unipedic support) and dynamic postural conditions (gait velocity and limits of stability) in order to compare the static and dynamic balance of these individuals. A cross-sectional quantitative study was carried out to evaluate static and dynamic balance in 25 sedentary individuals. The sample was divided into two groups, 10 in the normal-weight group (24.70 ± 3...
August 11, 2017: Clinical Obesity
https://www.readbyqxmd.com/read/28801940/examining-the-association-between-depression-and-obesity-during-a-weight-management-programme
#13
N R Fuller, J Burns, A Sainsbury, S Horsfield, F da Luz, S Zhang, G Denyer, T P Markovic, I D Caterson
The prevalence of depression in those with obesity is reported to be as high as double that in individuals of normal weight. There is potentially a bi-directional relationship between obesity and depression. Some research has suggested that depression results in weight gain and obesity, and other studies have suggested that those with obesity are more likely to develop depression at a later stage. The aim of this study was to investigate the association of depression symptoms with weight change over a 12-month study...
August 11, 2017: Clinical Obesity
https://www.readbyqxmd.com/read/28877558/social-status-and-energy-intake-a-randomized-controlled-experiment
#14
G Pavela, D W Lewis, J A Dawson, M Cardel, D B Allison
While the inverse association between socioeconomic status (SES) and obesity in high gross domestic product countries is well established using observational data, the extent to which the association is due to a true causal effect of SES and, if so, the mechanisms of this effect remain incompletely known. To assess the influence of social status on obesity via energy intake, we randomized individuals to a higher or lower social status and observed subsequent energy intake. College students between the ages of 18 and 25 were randomized to social status and were operationalized as being a leader or follower in a partner activity as purportedly determined by a (bogus) test of leadership ability...
October 2017: Clinical Obesity
https://www.readbyqxmd.com/read/28877557/can-we-reconcile-the-obesity-paradox-with-recent-cardiovascular-outcome-trials-in-diabetes
#15
A Jamieson, N Finer
No abstract text is available yet for this article.
October 2017: Clinical Obesity
https://www.readbyqxmd.com/read/28744976/patient-experiences-of-adjusting-to-life-in-the-first-2%C3%A2-years-after-bariatric-surgery-a-qualitative-study
#16
Y Graham, C Hayes, P K Small, K Mahawar, J Ling
There is currently little research into the experiences of those who have undergone bariatric surgery, or how surgery affects their lives and social interactions. Adopting a constructivist grounded theory methodological approach with a constant comparative analytical framework, semi-structured interviews were carried out with 18 participants (11 female, 7 male) who had undergone permanent bariatric surgical procedures 5-24 months prior to interview. Findings revealed that participants regarded social encounters after bariatric surgery as underpinned by risk...
October 2017: Clinical Obesity
https://www.readbyqxmd.com/read/28707388/the-associations-of-large-for-gestational-age-and-infant-feeding-practices-with-children-s-body-mass-index-z-score-trajectories-the-early-childhood-longitudinal-study-birth-cohort
#17
M Salahuddin, A Pérez, N Ranjit, D M Hoelscher, S H Kelder
Very few studies have examined if high birth weight and infant feeding practices have implications for the trajectory of body mass index (BMI) growth across the early childhood period. The goal of this study was to assess if large-for-gestational-age (LGA) and infant feeding practices (exclusive breastfeeding for 6 months, and early introduction of complementary food prior to 4 months) are associated with BMI z-score trajectories over the early childhood period. Group-based trajectory modelling (GBTM) methods were employed to describe and classify developmental BMI z-score trajectories (the outcome of interest) in children from 9 months to 4 years of age (n = 4497) born to prenatal non-smoking mothers in the Early Childhood Longitudinal Study, Birth Cohort (2001-2005)...
October 2017: Clinical Obesity
https://www.readbyqxmd.com/read/28703480/walking-in-the-shoes-of-caregivers-of-children-with-obesity-supporting-caregivers-in-paediatric-weight-management
#18
I S Zenlea, B Thompson, D Fierheller, J Green, C Ulloa, A Wills, E Mansfield
To incorporate the perspectives and experiences of family caregivers of children with obesity, the KidFit Health and Wellness Clinic, a paediatric weight management programme, embedded feedback opportunities into various stages of programme development. Caregivers were eligible to participate if their children had completed initial 4-week group-based pilot programming or were currently receiving treatment in 10 or 12 week group-based programming. Data were collected through feedback session discussions, audio-recorded, transcribed verbatim and analysed thematically...
October 2017: Clinical Obesity
https://www.readbyqxmd.com/read/28695722/a-systematic-review-of-reviews-exploring-the-relationship-between-obesity-weight-loss-and-health-related-quality-of-life
#19
REVIEW
R L Kolotkin, J R Andersen
This is the first systematic review of reviews to assess the effect of obesity and weight loss on health-related quality of life (HRQoL). We identified 12 meta-analyses/systematic reviews published between January 2001 and July 2016. They addressed the following themes: (i) the relationship between weight/body mass index and HRQoL (baseline/pre-intervention; n = 2). (ii) HRQoL after weight loss (varied interventions and/or study design; n = 2). (iii) HRQoL after weight loss (randomized controlled trials only; n = 2)...
October 2017: Clinical Obesity
https://www.readbyqxmd.com/read/28695579/exploring-the-evidence-base-for-tier-3-weight-management-interventions-for-adults-a-systematic-review
#20
REVIEW
T J Brown, C O'Malley, J Blackshaw, V Coulton, A Tedstone, C Summerbell, L J Ells
Specialist weight management services provide a treatment option for severe obesity. The objective of the study is to review the characteristics, impact and practice implications of specialist weight management services for adults in the UK. Systematic review: EMBASE, MEDLINE and PsycINFO were searched from January 2005 to March 2016 with supplementary searches. Adults with a body mass index of ≥40 kg m(-2) , or ≥35 kg m(-2) with comorbidity or ≥30 kg m(-2) with type 2 diabetes and any study of multicomponent interventions, in any UK or Ireland setting, delivered by a specialist multidisciplinary team are the inclusion criteria...
October 2017: Clinical Obesity
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