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Journal of Gastric Cancer

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https://www.readbyqxmd.com/read/30276007/long-term-survival-after-repeated-local-therapy-and-salvage-chemotherapy-for-recurrent-metastases-from-gastric-cancer-a-case-report-and-literature-review
#1
Jihyun Kwon, Hye Sook Han, Hee Kyung Kim, Seung-Woo Baek, Yaewon Yang, Ki Hyeong Lee, Seung-Myoung Son, Won-Dong Kim, Dae Hoon Kim, Hyo Yung Yun
We report a rare case of long-term survival in a patient who received local therapy and salvage chemotherapy for recurrent metastases, along with a literature review. A 65-year-old male patient underwent subtotal gastrectomy for advanced gastric adenocarcinoma. Six months after gastrectomy, 2 metastatic intra-abdominal lymph node enlargements were detected, which were treated with radiotherapy. At 55 months after gastrectomy, an abdominal wall mass was detected, which was treated by surgical resection. The patient received 5-fluorouracil/leucovorin/irinotecan chemotherapy for 27 months before and after radiotherapy and docetaxel chemotherapy for 6 months after surgical resection of the abdominal wall metastasis...
September 2018: Journal of Gastric Cancer
https://www.readbyqxmd.com/read/30276006/cytoreductive-surgery-and-hyperthermic-intraperitoneal-chemotherapy-as-treatment-options-for-peritoneal-metastasis-of-advanced-gastric-cancer
#2
Dong-Wook Kim, Dong-Guk Park, Sanghyun Song, Ye Seob Jee
Purpose: This study aimed to examine the outcomes of cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) in patients with peritoneal metastasis (PM) of advanced gastric cancer (AGC). Materials and Methods: Between May 2015 and June 2017, 38 CRS and HIPEC procedures were performed in patients with PM of AGC at the Dankook University Hospital. We prospectively collected and analyzed data regarding PM grade, morbidity and mortality rates, and short-term follow-up results (median, 13...
September 2018: Journal of Gastric Cancer
https://www.readbyqxmd.com/read/30276005/safety-of-laparoscopic-radical-gastrectomy-in-gastric-cancer-patients-with-end-stage-renal-disease
#3
Hayemin Lee, Cho Hyun Park, Seung Man Park, Wook Kim, Hyung Min Chin, Jin Jo Kim, Kyo Young Song, Sung Geun Kim, Kyong Hwa Jun, Jeong Goo Kim, Han Hong Lee, Junhyun Lee, Dong Jin Kim
Purpose: The surgical outcomes of end-stage renal disease (ESRD) patients undergoing radical gastrectomy for gastric cancer were inferior compared with those of non-ESRD patients. This study aimed to evaluate the short- and long-term surgical outcomes of ESRD patients undergoing laparoscopic gastrectomy (LG) and open gastrectomy (OG) for gastric cancer. Materials and Methods: Between 2004 and 2014, 38 patients (OG: 21 patients, LG: 17 patients) with ESRD underwent gastrectomy for gastric cancer...
September 2018: Journal of Gastric Cancer
https://www.readbyqxmd.com/read/30276004/the-impact-of-preoperative-low-body-mass-index-on-postoperative-complications-and-long-term-survival-outcomes-in-gastric-cancer-patients
#4
Chang Hyun Kim, Seung-Man Park, Jin-Jo Kim
Purpose: The aim of this study was to investigate the impact of preoperative low body mass index (BMI) on both the short- and long-term outcomes in patients with gastric cancer. Materials and Methods: A total of 510 patients with gastric cancer were divided into the following 3 groups: low BMI group (≤18.5 kg/m2 , n=51), normal BMI group (18.6-24.9 kg/m2 , n=308), and high BMI group (≥25.0 kg/m2 , n=151). Results: There were significantly more stage III/IV patients in the low BMI group than in the other groups (P=0...
September 2018: Journal of Gastric Cancer
https://www.readbyqxmd.com/read/30276003/who-can-perform-adjuvant-chemotherapy-treatment-for-gastric-cancer-a-multicenter-retrospective-overview-of-the-current-status-in-korea
#5
Jae-Seok Min, Chang Min Lee, Sung Il Choi, Kyung Won Seo, Do Joong Park, Yong Hae Baik, Myoung-Won Son, Won Hyuk Choi, Sungsoo Kim, Kyung Ho Pak, Min Gyu Kim, Joong-Min Park, Sang Ho Jeong, Moon-Soo Lee, Sungsoo Park
Purpose: To investigate the current status of adjuvant chemotherapy (AC) regimens in Korea and the difference in efficacy of AC administered by surgical and medical oncologists in patients with stage II or III gastric cancers. Materials and Methods: We performed a retrospective observational study among 1,049 patients who underwent curative resection and received AC for stage II and III gastric cancers between February 2012 and December 2013 at 29 tertiary referral university hospitals in Korea...
September 2018: Journal of Gastric Cancer
https://www.readbyqxmd.com/read/30276002/impact-of-various-types-of-comorbidities-on-the-outcomes-of-laparoscopic-total-gastrectomy-in-patients-with-gastric-carcinoma
#6
Oh Jeong, Mi Ran Jung, Seong Yeob Ryu
Purpose: With increasing life expectancy, the presence of comorbidities has become a major concern in elderly patients who require surgery. However, little is known about the impact of different comorbidities on the outcomes of laparoscopic total gastrectomy (LTG). In this study, we investigated the impact of comorbidities on postoperative complications in patients undergoing LTG for gastric carcinoma. Materials and Methods: We retrospectively reviewed the cases of 303 consecutive patients who underwent LTG for gastric carcinoma between 2005 and 2016...
September 2018: Journal of Gastric Cancer
https://www.readbyqxmd.com/read/30276001/sarcopenia-and-post-operative-morbidity-and-mortality-in-patients-with-gastric-cancer
#7
Stephen O'Brien, Maria Twomey, Fiachra Moloney, Richard G Kavanagh, Brian W Carey, Derek Power, Michael M Maher, Owen J O'Connor, Criostoir Ó'Súilleabháin
Purpose: Surgical resection for gastric adenocarcinoma is associated with significant post-operative morbidity and mortality. The aim of this study was to assess the prognostic significance of sarcopenia in patients undergoing resection for gastric adenocarcinoma with respect to post-operative morbidity and survival. Materials and Methods: A retrospective analysis was conducted on a cohort of consecutive patients who underwent surgical resection for gastric adenocarcinoma between 2008 and 2014...
September 2018: Journal of Gastric Cancer
https://www.readbyqxmd.com/read/30276000/enhanced-recovery-after-surgery-for-gastric-cancer-patients-improves-clinical-outcomes-at-a-us-cancer-center
#8
Jacopo Desiderio, Camille L Stewart, Virginia Sun, Laleh Melstrom, Susanne Warner, Byrne Lee, Hans F Schoellhammer, Vijay Trisal, Benjamin Paz, Yuman Fong, Yanghee Woo
Purpose: Enhanced recovery after surgery (ERAS) protocols for gastric cancer patients have shown improved outcomes in Asia. However, data on gastric cancer ERAS (GC-ERAS) programs in the United States are sparse. The purpose of this study was to compare perioperative outcomes before and after implementation of an GC-ERAS protocol at a National Comprehensive Cancer Center in the United States. Materials and Methods: We reviewed medical records of patients surgically treated for gastric cancer with curative intent from January 2012 to October 2016 and compared the GC-ERAS group (November 1, 2015-October 1, 2016) with the historical control (HC) group (January 1, 2012-October 31, 2015)...
September 2018: Journal of Gastric Cancer
https://www.readbyqxmd.com/read/30275999/preoperative-nodal-18-f-fdg-avidity-rather-than-primary-tumor-avidity-determines-the-prognosis-of-patients-with-advanced-gastric-cancer
#9
Hyun Woo Kwon, Liang An, Hye Ryeong Kwon, Sungsoo Park, Sungeun Kim
Purpose: This study investigated whether the metabolic avidity of primary tumors and/or metastatic lymph nodes (LNs) measured by 18 F-fluorodeoxyglucose (18 F-FDG) positron emission tomography/computed tomography (PET/CT) was related to survival after surgery in patients with advanced gastric cancer (AGC). Materials and Methods: One hundred sixty-eight patients with AGC who underwent preoperative 18 F-FDG PET/CT and curative resection were included. The 18 F-FDG avidity of the primary gastric tumor and LNs was determined quantitatively and qualitatively...
September 2018: Journal of Gastric Cancer
https://www.readbyqxmd.com/read/30275998/surgical-treatment-of-gastroesophageal-junction-cancer
#10
REVIEW
Tadayoshi Hashimoto, Yukinori Kurokawa, Masaki Mori, Yuichiro Doki
Although the incidence of gastroesophageal junction (GEJ) adenocarcinoma has been increasing worldwide, no standardized surgical strategy for its treatment has been established. This study aimed to provide an update on the surgical treatment of GEJ adenocarcinoma by reviewing previous reports and propose recommended surgical approaches. The Siewert classification is widely used for determining which surgical procedure is used, because previous studies have shown that the pattern of lymph node (LN) metastasis depends on tumor location...
September 2018: Journal of Gastric Cancer
https://www.readbyqxmd.com/read/29984071/erratum-is-lymph-node-size-a-reliable-factor-for-estimating-lymph-node-metastasis-in-early-gastric-cancer
#11
Dong Jin Kim, Wook Kim
[This corrects the article on p. 20 in vol. 18, PMID: 29629217.].
June 2018: Journal of Gastric Cancer
https://www.readbyqxmd.com/read/29984070/multiregion-comprehensive-genomic-profiling-of-a-gastric-mixed-neuroendocrine-nonneuroendocrine-neoplasm-with-trilineage-differentiation
#12
Faheem Farooq, Kevin Zarrabi, Keith Sweeney, Joseph Kim, Jela Bandovic, Chiraag Patel, Minsig Choi
Mixed neuroendocrine-nonneuroendocrine neoplasms (MiNENs) are a group of rare tumors previously known as mixed adenoneuroendocrine carcinomas (MANECs). The neuroendocrine component is high-grade and may consist of small-cell carcinoma or large-cell neuroendocrine carcinoma. The nonneuroendocrine component may consist of adenocarcinoma or squamous cell carcinoma. We report a unique case of a MiNEN with trilineage differentiation: large-cell neuroendocrine carcinoma, squamous cell carcinoma, and adenocarcinoma...
June 2018: Journal of Gastric Cancer
https://www.readbyqxmd.com/read/29984069/long-term-nutritional-outcomes-of-near-total-gastrectomy-in-gastric-cancer-treatment-a-comparison-with-total-gastrectomy-using-propensity-score-matching-analysis
#13
Ho Seok Seo, Yoon Ju Jung, Ji Hyun Kim, Cho Hyun Park, In Ho Kim, Han Hong Lee
Purpose: This study sought to examine whether near total gastrectomy (nTG) confers a long-term nutritional benefit when compared with total gastrectomy (TG) for the treatment of gastric cancer. Materials and Methods: Patients who underwent nTG or TG for gastric cancer were included (n=570). Using the 1:2 matched propensity score, 25 patients from the nTG group and 50 patients from the TG group were compared retrospectively for oncologic outcomes, including long-term survival and nutritional status...
June 2018: Journal of Gastric Cancer
https://www.readbyqxmd.com/read/29984068/learning-curve-of-pure-single-port-laparoscopic-distal-gastrectomy-for-gastric-cancer
#14
Boram Lee, Yoon Taek Lee, Young Suk Park, Sang-Hoon Ahn, Do Joong Park, Hyung-Ho Kim
Purpose: Despite the fact that there are several reports of single-port laparoscopic distal gastrectomy (SPDG), no analysis of its learning curve has been described in the literature. The aim of this study was to investigate the favorable factors for SPDG and to analyze the learning curve of SPDG. Materials and Methods: A total of 125 cases of SPDG performed from November 2011 to December 2015 were enrolled. All operations were performed by 2 surgeons (surgeon A and surgeon B)...
June 2018: Journal of Gastric Cancer
https://www.readbyqxmd.com/read/29984067/transition-from-conventional-to-reduced-port-laparoscopic-gastrectomy-to-treat-gastric-carcinoma-a-single-surgeon-s-experience-from-a-small-volume-center
#15
Ho Goon Kim, Dong Yi Kim, Oh Jeong
Purpose: This study aimed to evaluate the surgical outcomes and investigate the feasibility of reduced-port laparoscopic gastrectomy using learning curve analysis in a small-volume center. Materials and Methods: We reviewed 269 patients who underwent laparoscopic distal gastrectomy (LDG) for gastric carcinoma between 2012 and 2017. Among them, 159 patients underwent reduced-port laparoscopic gastrectomy. The cumulative sum technique was used for quantitative assessment of the learning curve...
June 2018: Journal of Gastric Cancer
https://www.readbyqxmd.com/read/29984066/assessment-of-the-completeness-of-lymph-node-dissection-using-near-infrared-imaging-with-indocyanine-green-in-laparoscopic-gastrectomy-for-gastric-cancer
#16
Tae-Han Kim, Seong-Ho Kong, Ji-Ho Park, Yong-Gil Son, Yeon-Ju Huh, Yun-Suhk Suh, Hyuk-Joon Lee, Han-Kwang Yang
Purpose: This study assessed the feasibility of near-infrared (NIR) imaging with indocyanine green (ICG) in investigating the completeness of laparoscopic lymph node (LN) dissection for gastric cancer. Materials and Methods: Patients scheduled for laparoscopic gastrectomy for treating gastric cancer were enrolled in the study. After intraoperative submucosal ICG injection (0.05 mg/mL), LN dissection was performed under conventional laparoscopic light. After dissection, the LN stations of interest were examined under the NIR mode to locate any extra ICG-stained (E) tissues, which were excised and sent for pathologic confirmation...
June 2018: Journal of Gastric Cancer
https://www.readbyqxmd.com/read/29984065/feasibility-and-safety-of-totally-laparoscopic-radical-gastrectomy-for-advanced-gastric-cancer-comparison-with-early-gastric-cancer
#17
Seungyeob Lee, Hayemin Lee, Junhyun Lee
Purpose: Totally laparoscopic gastrectomy (TLG) for advanced gastric cancer (AGC) is a technically and oncologically challenging procedure for surgeons. This study aimed to compare the oncologic feasibility and technical safety of TLG for AGC versus early gastric cancer (EGC). Materials and Methods: Between 2011 and 2016, 535 patients (EGC, 375; AGC, 160) underwent curative TLG for gastric cancer. Clinicopathologic characteristics and surgical outcomes of both patient groups were analyzed and compared...
June 2018: Journal of Gastric Cancer
https://www.readbyqxmd.com/read/29984064/modification-of-the-tnm-staging-system-for-stage-ii-iii-gastric-cancer-based-on-a-prognostic-single-patient-classifier-algorithm
#18
Yoon Young Choi, Eunji Jang, Won Jun Seo, Taeil Son, Hyoung-Il Kim, Hyeseon Kim, Woo Jin Hyung, Yong-Min Huh, Sung Hoon Noh, Jae-Ho Cheong
Purpose: The modification of the cancer classification system aimed to improve the classical anatomy-based tumor, node, metastasis (TNM) staging by considering tumor biology, which is associated with patient prognosis, because such information provides additional precision and flexibility. Materials and Methods: We previously developed an mRNA expression-based single patient classifier (SPC) algorithm that could predict the prognosis of patients with stage II/III gastric cancer...
June 2018: Journal of Gastric Cancer
https://www.readbyqxmd.com/read/29984063/pancreatic-compression-during-lymph-node-dissection-in-laparoscopic-gastrectomy-possible-cause-of-pancreatic-leakage
#19
Satoshi Ida, Naoki Hiki, Takeaki Ishizawa, Yugo Kuriki, Mako Kamiya, Yasuteru Urano, Takuro Nakamura, Yasuo Tsuda, Yosuke Kano, Koshi Kumagai, Souya Nunobe, Manabu Ohashi, Takeshi Sano
Purpose: Postoperative pancreatic fistula is a serious and fatal complication of gastrectomy for gastric cancer. Blunt trauma to the parenchyma of the pancreas can result from an assistant's forceps compressing and retracting the pancreas, which in turn may result in pancreatic juice leakage. However, no published studies have focused on blunt trauma to the pancreas during laparoscopic surgery. Our aim was to investigate the relationship between compression of the pancreas and pancreatic juice leakage in a swine model...
June 2018: Journal of Gastric Cancer
https://www.readbyqxmd.com/read/29984062/feasibility-and-effects-of-a-postoperative-recovery-exercise-program-developed-specifically-for-gastric-cancer-patients-prep-gc-undergoing-minimally-invasive-gastrectomy
#20
In Cho, Younsun Son, Sejong Song, Yoon Jung Bae, Youn Nam Kim, Hyoung-Il Kim, Dae Taek Lee, Woo Jin Hyung
Purpose: Exercise intervention after surgery has been found to improve physical fitness and quality of life (QOL). The purpose of this study was to investigate the feasibility and effects of a postoperative recovery exercise program developed specifically for gastric cancer patients (PREP-GC) undergoing minimally invasive gastrectomy. Materials and Methods: Twenty-four patients treated surgically for early gastric cancer were enrolled in the PREP-GC. The exercise program comprised sessions of In-hospital Exercise (1 week), Home Exercise (1 week), and Fitness Improvement Exercise (8 weeks)...
June 2018: Journal of Gastric Cancer
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