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Journal of Gastric Cancer

Dong Jin Kim, Wook Kim
[This corrects the article on p. 20 in vol. 18, PMID: 29629217.].
June 2018: Journal of Gastric Cancer
Faheem Farooq, Kevin Zarrabi, Keith Sweeney, Joseph Kim, Jela Bandovic, Chiraag Patel, Minsig Choi
Mixed neuroendocrine-nonneuroendocrine neoplasms (MiNENs) are a group of rare tumors previously known as mixed adenoneuroendocrine carcinomas (MANECs). The neuroendocrine component is high-grade and may consist of small-cell carcinoma or large-cell neuroendocrine carcinoma. The nonneuroendocrine component may consist of adenocarcinoma or squamous cell carcinoma. We report a unique case of a MiNEN with trilineage differentiation: large-cell neuroendocrine carcinoma, squamous cell carcinoma, and adenocarcinoma...
June 2018: Journal of Gastric Cancer
Ho Seok Seo, Yoon Ju Jung, Ji Hyun Kim, Cho Hyun Park, In Ho Kim, Han Hong Lee
Purpose: This study sought to examine whether near total gastrectomy (nTG) confers a long-term nutritional benefit when compared with total gastrectomy (TG) for the treatment of gastric cancer. Materials and Methods: Patients who underwent nTG or TG for gastric cancer were included (n=570). Using the 1:2 matched propensity score, 25 patients from the nTG group and 50 patients from the TG group were compared retrospectively for oncologic outcomes, including long-term survival and nutritional status...
June 2018: Journal of Gastric Cancer
Boram Lee, Yoon Taek Lee, Young Suk Park, Sang-Hoon Ahn, Do Joong Park, Hyung-Ho Kim
Purpose: Despite the fact that there are several reports of single-port laparoscopic distal gastrectomy (SPDG), no analysis of its learning curve has been described in the literature. The aim of this study was to investigate the favorable factors for SPDG and to analyze the learning curve of SPDG. Materials and Methods: A total of 125 cases of SPDG performed from November 2011 to December 2015 were enrolled. All operations were performed by 2 surgeons (surgeon A and surgeon B)...
June 2018: Journal of Gastric Cancer
Ho Goon Kim, Dong Yi Kim, Oh Jeong
Purpose: This study aimed to evaluate the surgical outcomes and investigate the feasibility of reduced-port laparoscopic gastrectomy using learning curve analysis in a small-volume center. Materials and Methods: We reviewed 269 patients who underwent laparoscopic distal gastrectomy (LDG) for gastric carcinoma between 2012 and 2017. Among them, 159 patients underwent reduced-port laparoscopic gastrectomy. The cumulative sum technique was used for quantitative assessment of the learning curve...
June 2018: Journal of Gastric Cancer
Tae-Han Kim, Seong-Ho Kong, Ji-Ho Park, Yong-Gil Son, Yeon-Ju Huh, Yun-Suhk Suh, Hyuk-Joon Lee, Han-Kwang Yang
Purpose: This study assessed the feasibility of near-infrared (NIR) imaging with indocyanine green (ICG) in investigating the completeness of laparoscopic lymph node (LN) dissection for gastric cancer. Materials and Methods: Patients scheduled for laparoscopic gastrectomy for treating gastric cancer were enrolled in the study. After intraoperative submucosal ICG injection (0.05 mg/mL), LN dissection was performed under conventional laparoscopic light. After dissection, the LN stations of interest were examined under the NIR mode to locate any extra ICG-stained (E) tissues, which were excised and sent for pathologic confirmation...
June 2018: Journal of Gastric Cancer
Seungyeob Lee, Hayemin Lee, Junhyun Lee
Purpose: Totally laparoscopic gastrectomy (TLG) for advanced gastric cancer (AGC) is a technically and oncologically challenging procedure for surgeons. This study aimed to compare the oncologic feasibility and technical safety of TLG for AGC versus early gastric cancer (EGC). Materials and Methods: Between 2011 and 2016, 535 patients (EGC, 375; AGC, 160) underwent curative TLG for gastric cancer. Clinicopathologic characteristics and surgical outcomes of both patient groups were analyzed and compared...
June 2018: Journal of Gastric Cancer
Yoon Young Choi, Eunji Jang, Won Jun Seo, Taeil Son, Hyoung-Il Kim, Hyeseon Kim, Woo Jin Hyung, Yong-Min Huh, Sung Hoon Noh, Jae-Ho Cheong
Purpose: The modification of the cancer classification system aimed to improve the classical anatomy-based tumor, node, metastasis (TNM) staging by considering tumor biology, which is associated with patient prognosis, because such information provides additional precision and flexibility. Materials and Methods: We previously developed an mRNA expression-based single patient classifier (SPC) algorithm that could predict the prognosis of patients with stage II/III gastric cancer...
June 2018: Journal of Gastric Cancer
Satoshi Ida, Naoki Hiki, Takeaki Ishizawa, Yugo Kuriki, Mako Kamiya, Yasuteru Urano, Takuro Nakamura, Yasuo Tsuda, Yosuke Kano, Koshi Kumagai, Souya Nunobe, Manabu Ohashi, Takeshi Sano
Purpose: Postoperative pancreatic fistula is a serious and fatal complication of gastrectomy for gastric cancer. Blunt trauma to the parenchyma of the pancreas can result from an assistant's forceps compressing and retracting the pancreas, which in turn may result in pancreatic juice leakage. However, no published studies have focused on blunt trauma to the pancreas during laparoscopic surgery. Our aim was to investigate the relationship between compression of the pancreas and pancreatic juice leakage in a swine model...
June 2018: Journal of Gastric Cancer
In Cho, Younsun Son, Sejong Song, Yoon Jung Bae, Youn Nam Kim, Hyoung-Il Kim, Dae Taek Lee, Woo Jin Hyung
Purpose: Exercise intervention after surgery has been found to improve physical fitness and quality of life (QOL). The purpose of this study was to investigate the feasibility and effects of a postoperative recovery exercise program developed specifically for gastric cancer patients (PREP-GC) undergoing minimally invasive gastrectomy. Materials and Methods: Twenty-four patients treated surgically for early gastric cancer were enrolled in the PREP-GC. The exercise program comprised sessions of In-hospital Exercise (1 week), Home Exercise (1 week), and Fitness Improvement Exercise (8 weeks)...
June 2018: Journal of Gastric Cancer
Dong Jin Kim, Wook Kim
Purpose: This study aimed to investigate the outcomes of laparoscopic gastrectomy in very elderly patients with gastric cancer, who have outlived the average lifespan of the Korean population (men: ≥77 years, women: ≥84 years). Materials and Methods: Between 2004 and 2015, 836 patients with gastric cancer underwent a laparoscopic gastrectomy. They were divided into the elderly group (EldG) and non-elderly group (nEldG). Propensity score matching for covariates of sex, tumor depth, node status, and extent of resection was performed...
June 2018: Journal of Gastric Cancer
Ho Seok Seo, Yoon Ju Jung, Cho Hyun Park, Kyo Young Song, Eun Sun Jung
Immunoglobulin G4-related disease (IgG4-RD) is an immune-mediated fibro-inflammatory disorder characterized by specific pathological findings and elevated serum IgG4 level. IgG4-RD in the stomach is rare, and occasionally diagnosed as gastric subepithelial tumor (SET) by endoscopy or computed tomography scan. Two female patients in the age group of 40-50 years were diagnosed with 4 cm sized gastric SET. One underwent laparoscopic gastric wedge resection. Another one had a history of subtotal gastrectomy for early gastric cancer and idiopathic thrombocytopenic purpura with oral steroids administration...
March 2018: Journal of Gastric Cancer
Ji Yeong An, Su Mi Kim, Soohyun Ahn, Min-Gew Choi, Jun-Ho Lee, Tae Sung Sohn, Jae-Moon Bae, Sung Kim
Purpose: We evaluated the learning curve and short-term surgical outcomes of robot-assisted distal gastrectomy (RADG) performed by a single surgeon experienced in open, but not laparoscopic, gastrectomy. We aimed to verify the feasibility of performing RADG without extensive laparoscopic experience. Materials and Methods: Between July 2012 and December 2016, 60 RADG procedures were performed by a single surgeon using the da Vinci® Surgical System (Intuitive Surgical)...
March 2018: Journal of Gastric Cancer
Jie-Hyun Kim, Sung Soo Kim, Jeong Hoon Lee, Da Hyun Jung, Dae Young Cheung, Woo-Chul Chung, Soo-Heon Park
Purpose: Early detection of gastric cancer is important to improve prognosis. Early detection enables local treatment, such as endoscopic submucosal dissection (ESD). Therefore, we investigated whether early detection of gastric cancer could reduce healthcare costs by comparison according to stage and treatment modalities. Materials and Methods: Medical care costs were investigated according to tumor stage and initial treatment modality in 1,188 patients newly diagnosed with gastric cancer at 7 medical institutions from December 2011 to June 2012...
March 2018: Journal of Gastric Cancer
Bang Wool Eom, Sohee Kim, Ja Yeon Kim, Hong Man Yoon, Mi-Jung Kim, Byung-Ho Nam, Young-Woo Kim, Young-Iee Park, Sook Ryun Park, Keun Won Ryu
Purpose: It has been reported that the survival of patients with locally advanced gastric cancer (LAGC) is better in East Asia countries than in developed western countries; however, the prognosis of LAGC remains poor. This study aimed to evaluate the effects of perioperative chemotherapy on the long-term survival of East Asia patients with LAGC. Materials and Methods: From October 2006 through August 2008, 43 patients with LAGC received perioperative S-1 combined with weekly docetaxel in a phase II study (neoadjuvant group)...
March 2018: Journal of Gastric Cancer
Yoontaek Lee, Sa-Hong Min, Ki Bum Park, Young Suk Park, Ji-Won Kim, Sang-Hoon Ahn, Jin Won Kim, Do Joong Park, Keun-Wook Lee, Hyung-Ho Kim
Purpose: Generally, adjuvant chemotherapy (AC) should be initiated as soon as possible after surgery to eradicate microscopic cancer cells. In this study, we investigated the effect of early AC on the survival of stage II/III gastric cancer patients. Materials and Methods: Four hundred sixty patients who received AC (S-1 or XELOX) for pathologic stage II/III gastric cancer at Seoul National University Bundang Hospital between January 2008 and December 2014 were included...
March 2018: Journal of Gastric Cancer
Sung Ho Jang, Young Jae Jung, Min Gyu Kim, Sung Joon Kwon
Purpose: Postoperative adjuvant chemotherapy is usually prescribed to improve the survival of patients with advanced gastric cancer who undergo curative surgery. This study was designed to determine the impact that the degree of compliance with chemotherapy has on the prognosis of patients with gastric cancer. Materials and Methods: Among 252 patients with stage III gastric cancer who underwent curative surgery between July 2004 and December 2014, 85 patients were postoperatively treated with S-1, the oral fluoropyrimidine derivative, 23 received no chemotherapy, and 144 received other regimens...
March 2018: Journal of Gastric Cancer
Gum Mo Jung, Seung Hyun Lee, Dae Seong Myung, Wan Sik Lee, Young Eun Joo, Mi Ran Jung, Seong Yeob Ryu, Young Kyu Park, Sung Bum Cho
Purpose: The endoscopic management of a fully covered self-expandable metal stent (SEMS) has been suggested for the primary treatment of patients with anastomotic leaks after total gastrectomy. Embedded stents due to tissue ingrowth and migration are the main obstacles in endoscopic stent management. Materials and Methods: The effectiveness and safety of endoscopic management were evaluated for anastomotic leaks when using a benign fully covered SEMS with an anchoring thread and thick silicone covering the membrane to prevent stent embedding and migration...
March 2018: Journal of Gastric Cancer
Ji Yeong An, Jae Seok Min, Young Joon Lee, Sang Ho Jeong, Hoon Hur, Sang Uk Han, Woo Jin Hyung, Gyu Seok Cho, Gui Ae Jeong, Oh Jeong, Young Kyu Park, Mi Ran Jung, Ji Yeon Park, Young Woo Kim, Hong Man Yoon, Bang Wool Eom, Keun Won Ryu
Purpose: We investigated complications after laparoscopic sentinel basin dissection (SBD) for patients with gastric cancer who were enrolled in a quality control study, prior to the phase III trial of sentinel lymph node navigation surgery (SNNS). Materials and Methods: We analyzed prospective data from a Korean multicenter prerequisite quality control trial of laparoscopic SBD for gastric cancer and assessed procedure-related and surgical complications. All complications were classified according to the Clavien-Dindo Classification (CDC) system and were compared with the results of the previously published SNNS trial...
March 2018: Journal of Gastric Cancer
Dong Jin Kim, Wook Kim
Purpose: Pre-operative lymph node (LN) size is a valuable parameter for determining treatment strategy for gastric cancer. However, a correlation between LN size and metastasis has not been established. Materials and Methods: Thirty-six LN-positive (LNP) and matched 36 LN-negative (LNN) patients were included, and pathology slides of the LNs of these patients were reviewed. All the LNs were measured along the long-axis (LA) and short-axis (SA), manually. Results: Average retrieved LNs were 37...
March 2018: Journal of Gastric Cancer
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