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Practical Radiation Oncology

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https://www.readbyqxmd.com/read/28428019/radiation-therapy-for-oropharyngeal-squamous-cell-carcinoma-executive-summary-of-an-astro-evidence-based-clinical-practice-guideline
#1
David J Sher, David J Adelstein, Gopal K Bajaj, David M Brizel, Ezra E W Cohen, Aditya Halthore, Louis B Harrison, Charles Lu, Benjamin J Moeller, Harry Quon, James W Rocco, Erich M Sturgis, Roy B Tishler, Andy Trotti, John Waldron, Avraham Eisbruch
PURPOSE: To present evidence-based guidelines for the treatment of oropharyngeal squamous cell carcinoma (OPSCC) with definitive or adjuvant radiation therapy (RT). METHODS AND MATERIALS: The American Society for Radiation Oncology convened the OPSCC Guideline Panel to perform a systematic literature review investigating the following key questions: (1) When is it appropriate to add systemic therapy to definitive RT in the treatment of OPSCC? (2) When is it appropriate to deliver postoperative RT with and without systemic therapy following primary surgery for OPSCC? (3) When is it appropriate to use induction chemotherapy in the treatment of OPSCC? (4) What are the appropriate dose, fractionation, and volume regimens with and without systemic therapy in the treatment of OPSCC? RESULTS: Patients with stage IV and stage T3 N0-1 OPSCC treated with definitive RT should receive concurrent high-dose intermittent cisplatin...
April 11, 2017: Practical Radiation Oncology
https://www.readbyqxmd.com/read/28501507/peering-over-the-chasm-diffusion-of-prostate-radiation-therapy-hypofractionation
#2
EDITORIAL
Mark K Buyyounouski
No abstract text is available yet for this article.
April 8, 2017: Practical Radiation Oncology
https://www.readbyqxmd.com/read/28433523/association-of-preresidency-peer-reviewed-publications-with-radiation-oncology-resident-choice-of-academic-versus-private-practice-career
#3
Shearwood McClelland, Charles R Thomas, Lynn D Wilson, Emma B Holliday, Jerry J Jaboin
INTRODUCTION: The decision of radiation oncology residents to pursue academic versus private practice careers plays a central role in shaping the present and future of the field, but factors that are potentially predictive of this decision are lacking. This study was performed to examine the role of several factors publicly available before residency on postresidency career choice, including preresidency peer-reviewed publications (PRPs), which have been associated with resident career choice in comparably competitive subspecialties such as neurosurgery...
April 5, 2017: Practical Radiation Oncology
https://www.readbyqxmd.com/read/28501508/military-metaphors-in-oncology-let-s-not-fight-about-this
#4
EDITORIAL
Benjamin W Corn
No abstract text is available yet for this article.
March 27, 2017: Practical Radiation Oncology
https://www.readbyqxmd.com/read/28438420/scalp-sparing-total-skin-electron-therapy-in-mycosis-fungoides-case-report-featuring-a-technique-without-lead
#5
Chirayu G Patel, George Ding, Austin Kirschner
No abstract text is available yet for this article.
March 27, 2017: Practical Radiation Oncology
https://www.readbyqxmd.com/read/28462895/irradiation-of-anatomically-defined-pelvic-subsites-and-acute-hematologic-toxicity-in-anal-cancer-patients-undergoing-chemoradiation
#6
Brent Rose, Devarati Mitra, Theodore S Hong, Kyung-Wook Jee, Andrzej Niemierko, Lorraine N Drapek, Lawrence S Blaszkowsky, Jill N Allen, Janet E Murphy, Jeffrey W Clark, David P Ryan, Jennifer Y Wo
PURPOSE: Chemoradiation for the treatment of anal cancer is known to cause significant hematologic toxicity (HT). We sought to investigate if radiation dose to specific pelvic subsites is associated with increased HT risk. METHODS AND MATERIALS: Forty-five patients with nonmetastatic anal cancer who received definitive chemoradiation with intensity modulated radiation therapy and concurrent mitomycin-C and 5-fluorouracil were studied. Total pelvic bone marrow (TBM) was divided into 3 subsites: lumbosacral bone marrow (LSBM), including the entire sacrum and L5 vertebral body; iliac bone marrow (IBM) extending from the iliac crests to the superior border of the femoral head; and lower pelvic bone marrow, including the pubic bones, ischia, acetabula, and proximal femurs...
March 23, 2017: Practical Radiation Oncology
https://www.readbyqxmd.com/read/28462897/radiation-oncology-resident-palliative-education
#7
Monica Krishnan, Margarita Racsa, Joshua Jones, Eva Chittenden, Kristen G Schaefer, Alex Spektor, Andrea Enzinger, Randy Wei, Tracy Balboni
PURPOSE: Although palliative care is recognized as integral to oncology care, limited data exist regarding the extent to which palliative care training is incorporated into radiation oncology residency training in the United States. We aim to characterize US radiation oncology residents' perceived palliative care educational needs and experience to guide future palliative oncology educational interventions. METHODS AND MATERIALS: An 8-person expert panel developed a survey to assess resident perceptions of generalist palliative care education within radiation oncology residency...
March 14, 2017: Practical Radiation Oncology
https://www.readbyqxmd.com/read/28442242/dosimetric-analysis-of-liver-toxicity-after-liver-metastasis-stereotactic-body-radiation-therapy
#8
Aisling Barry, Andrew McPartlin, Patricia Lindsay, Lisa Wang, James Brierley, John Kim, Jolie Ringash, Rebecca Wong, Rob Dinniwell, Tim Craig, Laura A Dawson
PURPOSE: The aim of this study is to describe the incidence and type of liver toxicity seen following liver metastases stereotactic body radiation therapy (SBRT) and the corresponding clinical and dosimetric factors associated with toxicity. METHODS AND MATERIALS: Between 2002 and 2009, 81 evaluable patients with liver metastases were treated on 2 prospective studies assessing SBRT, with prescription doses based on the effective liver volume irradiated evaluated...
March 9, 2017: Practical Radiation Oncology
https://www.readbyqxmd.com/read/28428017/outcomes-and-toxicity-following-high-dose-radiation-therapy-in-15-fractions-for-non-small-cell-lung-cancer
#9
Penny Fang, Cameron W Swanick, Todd A Pezzi, Zhongxing Liao, James Welsh, Steven H Lin, Daniel R Gomez
PURPOSE: Accelerated hypofractionated radiation therapy (AHRT) is increasingly used for select lung cancer patients. We evaluated clinical outcomes and predictors of pulmonary/esophageal toxicity in patients treated with ≥52.5 Gy in 15 fractions. METHODS AND MATERIALS: We evaluated 229 patients treated with radiation therapy doses ≥52.5 Gy in 15 fractions for non-small cell lung cancer from January 2009 through January 2016. Toxicity was scored using Common Terminology Criteria for Adverse Events, v4...
March 9, 2017: Practical Radiation Oncology
https://www.readbyqxmd.com/read/28433522/metaphors-for-human-diseases
#10
LETTER
Giulio J D'Angio
No abstract text is available yet for this article.
March 6, 2017: Practical Radiation Oncology
https://www.readbyqxmd.com/read/28377141/patterns-of-lymph-node-positivity-on-11-c-acetate-pet-imaging-in-correlation-to-the-rtog-pelvic-radiation-field-for-prostate-cancer
#11
Chris McClinton, Maryam Niroumand, Sumit Sood, Veer Shah, Jacqueline Hill, Reginald W Dusing, Xinglei Shen
PURPOSE: (11)C-acetate positron emission tomography (PET) imaging allows for the detection of occult metastatic disease that may otherwise go undetected with standard imaging for prostate cancer (PCa). The aim of this study was to evaluate lymph node coverage of the standard Radiation Therapy Oncology Group (RTOG) whole pelvic radiation therapy (WPRT) field in patients found to have node-positive PCa determined by (11)C-acetate PET imaging. METHODS AND MATERIALS: A retrospective analysis was conducted on 125 PCa patients who underwent (11)C-acetate PET scans at our institution between 2007 and 2014...
March 6, 2017: Practical Radiation Oncology
https://www.readbyqxmd.com/read/28377138/daily-ct-guidance-improves-target-coverage-during-definitive-radiation-therapy-for-gastric-malt-lymphoma
#12
He Wang, Sarah A Milgrom, Bouthaina S Dabaja, Grace L Smith, Mary Martel, Chelsea C Pinnix
PURPOSE: Radiation therapy (RT) for gastric mucosa-associated lymphoid tissue (MALT) lymphoma is challenging because of variation in the stomach's position, size, and shape. We investigated the interfractional changes in stomach location, consequent dosimetric effects, and impact of daily computed tomography image guidance RT (CT-IGRT). METHODS AND MATERIALS: Twelve patients treated for gastric MALT lymphoma with intensity modulated radiation therapy, using a breath-hold technique and restriction of oral intake, were studied retrospectively...
March 6, 2017: Practical Radiation Oncology
https://www.readbyqxmd.com/read/28433524/an-analysis-of-knowledge-based-planning-for-stereotactic-body-radiation-therapy-of-the-spine
#13
Joseph J Foy, Robin Marsh, Randall K Ten Haken, Kelly C Younge, Matthew Schipper, Yilun Sun, Dawn Owen, Martha M Matuszak
PURPOSE: Planning for spine stereotactic body radiation therapy (SBRT) is time consuming, and differences in planner experience and technique result in discrepancies in plan quality between facilities. Here, knowledge-based planning is analyzed to determine if it may be effective in improving the quality and efficiency of spine SBRT planning. MATERIALS AND METHODS: Thirty-eight spine SBRT cases were collected from the University of Michigan database and inverse planned to deliver 3 10-Gy fractions to the planning target volume (PTV)...
March 2, 2017: Practical Radiation Oncology
https://www.readbyqxmd.com/read/28377137/hazards-and-incidents-detection-and-learning-in-radiation-medicine-a-comparison-of-2-educational-interventions
#14
Robert Thompson, Yilan Lu, Marc Potvin, Jordan Holmes, Lisa Di Prospero, Brian Keller, Ewa Szumacher, Brian Liszewski, Pamela Catton, Meredith Giuliani, Bethany Pitcher, Melania Pintilie, Jean-Pierre Bissonnette
PURPOSE: Interprofessional, educational live simulations were compared with group discussion-based exercises in terms of their ability to improve radiation medicine trainees' ability to detect hazards and incidents and understand behaviors that may prevent them. METHODS AND MATERIALS: Trainees and recent graduates of radiation therapy, medical physics, and radiation oncology programs were recruited and randomized to either a simulation-based or group discussion-based training intervention...
February 27, 2017: Practical Radiation Oncology
https://www.readbyqxmd.com/read/28477798/hippocampal-sparing-and-target-volume-coverage-in-treating-3-to-10-brain-metastases-a-comparison-of-gamma-knife-single-isocenter-vmat-cyberknife-and-tomotherapy-stereotactic-radiosurgery
#15
Isabella Zhang, Jeff Antone, Jenny Li, Shyamali Saha, Adam C Riegel, Lili Vijeh, Joe Lauritano, Mihaela Marrero, Sussan Salas, Michael Schulder, Heather Zinkin, Anuj Goenka, Jonathan Knisely
PURPOSE: Our purpose was to evaluate hippocampal doses and target volume coverage with and without hippocampal sparing when treating multiple brain metastases using various stereotactic radiosurgery (SRS) platforms. METHODS AND MATERIALS: We selected 10 consecutive patients with 14 separate treatments who had been treated in our department for 3 to 10 brain metastases and added hippocampal avoidance contours. All 14 treatments were planned with GammaPlan for Gamma Knife, Eclipse for single isocenter volumetric modulated arc therapy (VMAT), TomoTherapy Treatment Planning System (TPS) for TomoTherapy, and MultiPlan for CyberKnife...
May 2017: Practical Radiation Oncology
https://www.readbyqxmd.com/read/28395915/local-failure-and-acute-radiodermatological-toxicity-in-patients-undergoing-radiation-therapy-with-and-without-postmastectomy-chest-wall-bolus-is-bolus-ever-necessary
#16
Stephen Abel, Paul Renz, Mark Trombetta, Michael Cowher, E Day Werts, Thomas B Julian, Rodney Wegner
PURPOSE: Postmastectomy chest wall radiation therapy has historically used bolus to increase dose at the skin surface. Despite the theoretical benefits of bolus, the clinical implications of locoregional tumor control, cosmesis, and the incidence of radiodermatitis are less well characterized. We hypothesized that treatment in the presence or absence of bolus results in equivalent chest wall recurrence rates, but its presence results in more severe acute dermatologic toxicity. METHODS AND MATERIALS: Locally advanced breast cancer patients undergoing chest wall radiation therapy were retrospectively reviewed from 2005 to 2015 (n = 106; 53 with bolus, 53 without)...
May 2017: Practical Radiation Oncology
https://www.readbyqxmd.com/read/28363492/commentary-on-accelerated-partial-breast-irradiation-consensus-statement-update-of-an-astro-evidence-based-consensus-statement
#17
LETTER
William Small, Tarita O Thomas, Michael Alvarado, Michael Baum, Max Bulsara, Roberto Diaz, Eric Donnelly, Sheldon Feldman, Stephen Grobmyer, Richard Hoefer, David Joseph, Song Kang, Christine Laronga, Andrea McKee, Barry Rosen, Jeffrey Tobias, Valery Uhl, Jayant S Vaidya, Frederik Wenz, Dennis Holmes
No abstract text is available yet for this article.
May 2017: Practical Radiation Oncology
https://www.readbyqxmd.com/read/28343896/assessment-of-hepatic-function-decline-after-stereotactic-body-radiation-therapy-for-primary-liver-cancer
#18
Diego A S Toesca, Evan C Osmundson, Rie von Eyben, Jenny L Shaffer, Albert C Koong, Daniel T Chang
PURPOSE: This study aims to determine how the albumin-bilirubin (ALBI) score compares with the Child-Pugh (CP) score for assessing liver function following stereotactic body radiation therapy (SBRT). METHODS AND MATERIALS: In total, 60 patients, 40 with hepatocellular carcinoma (HCC) and 20 with cholangiocarcinoma (CCA), were treated with SBRT. Liver function panels were obtained before and at 1, 3, 6, and 12 months after SBRT. Laboratory values were censored after locoregional recurrence, further liver-directed therapies, or liver transplant...
May 2017: Practical Radiation Oncology
https://www.readbyqxmd.com/read/28277261/building-a-palliative-radiation-oncology-program-from-bedside-to-b-e-d
#19
Mark J Stavas, Jonathan D Pagan, Sumeeta Varma, Benjamin Li, Lisa A Kachnic
A growing body of evidence supports the integration of palliative care with standard cancer treatments. In these situations, patients often experience a better quality of life, better quality of care, decreased cost, and, in some cases, improved survival with the addition of palliative care services to traditional treatment pathways. In this manuscript, we explore the integration of radiation oncology at palliative care. First, we discuss the impetus for change at Vanderbilt University and the inception of Vanderbilt's inpatient Palliative Radiation Oncology Service at Vanderbilt...
May 2017: Practical Radiation Oncology
https://www.readbyqxmd.com/read/28196607/development-of-a-model-web-based-system-to-support-a-statewide-quality-consortium-in-radiation-oncology
#20
Jean M Moran, Mary Feng, Lisa A Benedetti, Robin Marsh, Kent A Griffith, Martha M Matuszak, Michael Hess, Matthew McMullen, Jennifer H Fisher, Teamour Nurushev, Margaret Grubb, Stephen Gardner, Daniel Nielsen, Reshma Jagsi, James A Hayman, Lori J Pierce
PURPOSE: A database in which patient data are compiled allows analytic opportunities for continuous improvements in treatment quality and comparative effectiveness research. We describe the development of a novel, web-based system that supports the collection of complex radiation treatment planning information from centers that use diverse techniques, software, and hardware for radiation oncology care in a statewide quality collaborative, the Michigan Radiation Oncology Quality Consortium (MROQC)...
May 2017: Practical Radiation Oncology
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