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Pulmonary Circulation

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https://www.readbyqxmd.com/read/29313743/express-resource-utilization-at-the-time-of-prostacyclin-initiation-in-children-in-pulmonary-arterial-hypertension-a-multicenter-analysis
#1
Stephen Hart, Gaurav Arora, Brian Feingold
No abstract text is available yet for this article.
January 1, 2018: Pulmonary Circulation
https://www.readbyqxmd.com/read/29309261/express-impaired-systemic-oxygen-extraction-in-treated-exercise-pulmonary-hypertension-a-new-engine-in-an-old-car
#2
Mariana Faria Urbina, Rudolf Oliveira, Sergio Andres Segrera, Laurie Lawler, Aaron B Waxman, David Systrom
No abstract text is available yet for this article.
January 1, 2018: Pulmonary Circulation
https://www.readbyqxmd.com/read/29309247/express-targeting-inflammation-and-immunity-in-pulmonary-arterial-hypertension-any-easier-after-the-cantos-proof-of-concept-that-anti-inflammation-cuts-cardiovascular-events
#3
https://www.readbyqxmd.com/read/29309246/express-balloon-pulmonary-angioplasty-does-it-have-a-role-in-chronic-thromboembolic-disease
#4
John Gerry Coghlan
No abstract text is available yet for this article.
January 1, 2018: Pulmonary Circulation
https://www.readbyqxmd.com/read/29309245/express-changes-in-endothelial-cytoskeleton-and-calcium-signaling-in-vascular-barrier-breakdown-a-response-of-ever-growing-complexity
#5
Alejandro Pablo Adam, Yun-Min Zheng, Yong-Xiao Wang
No abstract text is available yet for this article.
January 1, 2018: Pulmonary Circulation
https://www.readbyqxmd.com/read/29309237/express-central-line-replacement-following-infection-does-not-improve-reinfection-rates-in-pediatric-pulmonary-hypertension-patients-receiving-intravenous-prostanoid-therapy
#6
Elisa McCarthy, Michelle T Ogawa, Rachel K Hopper, Jeffrey A Feinstein, Hayley A Gans
No abstract text is available yet for this article.
January 1, 2018: Pulmonary Circulation
https://www.readbyqxmd.com/read/29308711/express-pulmonary-micro-tumor-emboli-resulting-in-paradoxical-emboli-a-case-report
#7
Louis-Vincent Morin-Thibault, Daniel Wiseman, Michelle Fortin, Christian Couture, Steeve Provencher
No abstract text is available yet for this article.
January 1, 2018: Pulmonary Circulation
https://www.readbyqxmd.com/read/29308704/express-right-atrial-mechanics-provide-useful-insight-in-pediatric-pulmonary-hypertension
#8
Kyle D Hope, Renzo J C Calderón Anyosa, Yan Wang, Andrea E Montero, Tomoyuki Sato, Brian D Hanna, Anirban Banerjee
No abstract text is available yet for this article.
January 1, 2018: Pulmonary Circulation
https://www.readbyqxmd.com/read/29384427/lessons-from-the-compass-3-study
#9
Trushil Shah, Kelly M Chin
No abstract text is available yet for this article.
January 2018: Pulmonary Circulation
https://www.readbyqxmd.com/read/29283043/endothelial-dysfunction-in-pulmonary-arterial-hypertension-an-evolving-landscape-2017-grover-conference-series
#10
Benoît Ranchoux, Lloyd D Harvey, Ramon J Ayon, Aleksandra Babicheva, Sebastien Bonnet, Stephen Y Chan, Jason X-J Yuan, Vinicio de Jesus Perez
Endothelial dysfunction is a major player in the development and progression of vascular pathology in pulmonary arterial hypertension (PAH), a disease associated with small vessel loss and obstructive vasculopathy that leads to increased pulmonary vascular resistance, subsequent right heart failure, and premature death. Over the past ten years, there has been tremendous progress in our understanding of pulmonary endothelial biology as it pertains to the genetic and molecular mechanisms that orchestrate the endothelial response to direct or indirect injury, and how their dysregulation can contribute to the pathogenesis of PAH...
January 2018: Pulmonary Circulation
https://www.readbyqxmd.com/read/29251545/multicenter-mortality-and-morbidity-associated-with-pulmonary-hypertension-in-the-pediatric-intensive-care-unit
#11
Emily Morell Balkin, Martina A Steurer, Elise A Delagnes, Matt S Zinter, Satish Rajagopal, Roberta L Keller, Jeffrey R Fineman
Despite advances in the diagnosis and management of pediatric pulmonary hypertension (PH), children with PH represent a growing inpatient population with significant morbidity and mortality. To date, no studies have described the clinical characteristics of children with PH in the pediatric intensive care unit (PICU). A retrospective multicenter cohort study of 153 centers in the Virtual PICU Systems database who submitted data between 1 January 2009 and 31 December 2015 was performed. A total of 14,880/670,098 admissions (2...
January 2018: Pulmonary Circulation
https://www.readbyqxmd.com/read/29249170/occult-catheter-rupture-causing-episodic-symptoms-in-a-patient-treated-with-epoprostenol
#12
Barbara L LeVarge, Anica C Law, Blanche Murphy
Infection, thrombosis, and catheter dislodgment are well-recognized potential complications of chronic intravenous prostanoid therapy for pulmonary arterial hypertension. As long-term outcomes of pulmonary hypertension patients improve, novel adverse events are likely to arise. We describe the sudden development of unexplained hypotension and lightheadedness in a patient receiving intravenous epoprostenol for several years, ultimately determined to be due to an unusual catheter complication, not previously described in this population...
January 2018: Pulmonary Circulation
https://www.readbyqxmd.com/read/29206084/identity-crisis-in-pulmonary-arterial-hypertension
#13
G Ruffenach, S Bonnet, S Rousseaux, S Khochbin, S Provencher, F Perros
Pulmonary arterial hypertension (PAH) shares many hallmarks with cancer. Cancer cells acquire their hallmarks by a pathological Darwinian evolution process built on the so-called cancer cell "identity crisis." Here we demonstrate that PAH shares the most striking features of the cancer identity crisis: the ectopic expression of normally silent tissue-specific genes.
January 2018: Pulmonary Circulation
https://www.readbyqxmd.com/read/29199910/impact-of-four-times-daily-dosing-of-oral-treprostinil-on-tolerability-and-daily-dose-achieved-in-pulmonary-hypertension
#14
James C Coons, Cheryl Bunner, David C Ishizawar, Michael G Risbano, Belinda Rivera-Lebron, Michael A Mathier, Stephen Y Chan, Marc A Simon
Oral treprostinil (TRE) is a prostacylin that is approved for the treatment of patients with pulmonary arterial hypertension (PAH). Dosing is approved for two or three times daily (t.i.d.); however, adverse effects, including gastrointestinal-related symptoms, may limit the ability to reach optimal doses. We report our experience with a four times daily (q.i.d.) regimen of oral TRE for goal-directed therapy of PAH. We describe three patients that were transitioned from infusion or inhaled TRE to oral TRE with initial t...
January 2018: Pulmonary Circulation
https://www.readbyqxmd.com/read/29199903/more-than-a-biomarker-the-systemic-consequences-of-heparan-sulfate-fragments-released-during-endothelial-surface-layer-degradation-2017-grover-conference-series
#15
Kaori Oshima, Sarah M Haeger, Joseph A Hippensteel, Paco S Herson, Eric P Schmidt
Advances in tissue fixation and imaging techniques have yielded increasing appreciation for the glycosaminoglycan-rich endothelial glycocalyx and its in vivo manifestation, the endothelial surface layer (ESL). Pathological loss of the ESL during critical illness promotes local endothelial dysfunction and, consequently, organ injury. Glycosaminoglycan fragments, such as heparan sulfate, are released into the plasma of animals and humans after ESL degradation and have thus served as a biomarker of endothelial injury...
January 2018: Pulmonary Circulation
https://www.readbyqxmd.com/read/29199900/a-prescribed-walking-regimen-plus-arginine-supplementation-improves-function-and-quality-of-life-for-patients-with-pulmonary-arterial-hypertension-a-pilot-study
#16
Mary Beth Brown, Attie Kempf, Catherine M Collins, Gary M Long, Matthew Owens, Shikha Gupta, Yaron Hellman, Vincent Wong, Mark Farber, Tim Lahm
Current evidence suggests that exercise training is beneficial in pulmonary arterial hypertension (PAH). Unfortunately, the standard supervised, hospital-based programs limit patient accessibility to this important intervention. Our proof-of-concept study aimed to provide insight into the usefulness of a prescribed walking regimen along with arginine supplementation to improve outcomes for patients with PAH. Twelve PAH patients (all women) in New York Heart Association (NYHA) functional class (FC) II (n = 7) or III (n = 5) and in stable condition for ≥ 3 months were enrolled...
January 2018: Pulmonary Circulation
https://www.readbyqxmd.com/read/29099661/first-in-child-use-of-the-oral-soluble-guanylate-cyclase-stimulator-riociguat-in-pulmonary-arterial-hypertension
#17
Till Spreemann, Harald Bertram, Christoph M Happel, Rainer Kozlik-Feldmann, Georg Hansmann
Riociguat has been approved for use in adults with pulmonary arterial hypertension (PAH) or chronic thromboembolic pulmonary hypertension. No clinical data on its therapeutic use in children with PAH are currently available. We report the case of a now four-year-old boy who initially presented at the age of 10 months with suprasystemic pulmonary hypertension (PH) and right ventricular (RV) failure, vomiting, peripheral cyanosis, and failure to thrive. Cardiac catheterization revealed severe PAH. At radiologic suspicion of interstitial lung disease, repeated CT scan and an open lung biopsy were performed but could not clarify the entity of PAH...
January 2018: Pulmonary Circulation
https://www.readbyqxmd.com/read/29168664/pulmonary-arterial-hypertension-and-acute-respiratory-distress-syndrome-in-a-patient-with-adult-onset-stills-disease
#18
Grant H Lowther, Jason Chertoff, Jessica Cope, Hassan Alnuaimat, Ali Ataya
Adult-onset Still's disease (AOSD) is an inflammatory disorder characterized by recurrent fevers, arthralgia, leukocytosis, and a salmon-colored rash. Diagnosis is made based on the Yamaguchi criteria. Various cardiac and pulmonary manifestations have been described in association with AOSD, including acute respiratory distress syndrome (ARDS) and pulmonary arterial hypertension (PAH). We describe the first case of both PAH and ARDS in a patient with AOSD who, despite aggressive therapy, declined rapidly and ultimately died...
October 2017: Pulmonary Circulation
https://www.readbyqxmd.com/read/29168663/macro-and-micro-heterogeneity-of-lung-endothelial-cells-they-may-not-be-smooth-but-they-got-the-moves
#19
Mohamad Taha, Virgilio J Cadete, Duncan J Stewart
No abstract text is available yet for this article.
October 2017: Pulmonary Circulation
https://www.readbyqxmd.com/read/29040048/pulmonary-vascular-research-institute-world-congress-2017-scientific-abstracts
#20
(no author information available yet)
No abstract text is available yet for this article.
October 2017: Pulmonary Circulation
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